Drub002328.1
Basic Information
- Insect
- Drosophila rubida
- Gene Symbol
- -
- Assembly
- GCA_035046165.1
- Location
- JAWNOF010000012.1:18999922-19005904[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.071 4.2 7.8 0.2 1 23 1358 1381 1358 1381 0.94 2 13 8 4.7e+02 1.4 0.2 1 23 1543 1565 1543 1565 0.91 3 13 0.00018 0.011 16.0 2.7 2 23 1568 1589 1568 1589 0.97 4 13 6.9e-05 0.0041 17.3 0.2 3 23 1597 1617 1595 1617 0.98 5 13 5.7e-07 3.4e-05 23.8 4.1 2 23 1624 1645 1623 1645 0.97 6 13 5.4 3.2e+02 1.9 0.4 5 23 1658 1676 1656 1676 0.96 7 13 1.3 79 3.8 5.4 3 23 1683 1704 1681 1704 0.93 8 13 0.14 8.5 6.9 0.2 2 23 1715 1735 1714 1735 0.96 9 13 5.5e-05 0.0032 17.6 0.4 1 19 1741 1759 1741 1763 0.95 10 13 1.6e-05 0.00093 19.3 0.5 1 23 1771 1793 1771 1793 0.98 11 13 0.0001 0.0061 16.8 7.6 1 23 1799 1821 1799 1822 0.96 12 13 0.0002 0.012 15.8 5.9 1 23 1827 1849 1827 1849 0.98 13 13 0.028 1.7 9.1 8.2 1 23 1855 1877 1855 1878 0.95
Sequence Information
- Coding Sequence
- atggTGGACAACAGTGTGCAGTGCCCGGTGTGCACCTTGTACCTGCATGCGGGCATGAATCTCTCCGATCATTTGGAGACACATCCCAAGGAGCAGGTGATCAAGGCATTGGTGCAAATGACAATCGTTGGCAACAACCCCATGGGCTGCAGcctggcggcagcagctgcactcgCCACTGCCGGCAGTGGCAGTCAAACTGCGGCGGCATCGTTGGACGGTGCCGCCTCCTCGACAGCGCCCGAAGCTGATGTGAAACCAGCTGTGgcagcaccaccagctgccccaacaccaccagcaccagcacctgCAACGCagacatcagcagcagcagcagcaacgacagcgaacgccacagctacaacaacaccaaGCACATTAAAATCAGCAGCACCAAAAGCTGCGTCATTGCtgggaaatgcaaatgccaacgCAAACatcaatagcagcagcagctccggcTCTAGTAGCAACAGCggctccagcagcaacagtaacaataacaaattgagCAATCCACCGATTAAGGCAGTCAAAAGCGCGCCACCGTCGACTGAGGCGTCAGCCACCACATCCAACACACCCACCATAAGCAGCGTGGCCGCCGCCTATCCGCCATCGTTGACACCCGACTGTCGCTacgatcagcagcagcagcagcagcagcaacaacatcaagcacagcaacaggcgacgccagcagcaacacttcATGGCTTTCCACGTGGTGCAACCACAATGTTGGTGATACCACAGGCTAcacagcatcaacatcatttCCTGGCCACGCATACTGCTCATTTTacccatcagcagcagcagcagcaacaacagtcgccTATGAAGTACACGTATGCGACTACGTTGCCACCACCACCTCCGCCACTACAGCTTTTTGCACAGCAGCCGACGTCAACGCAGTCGCATCAAAAGCCACCACCAGCCTATGGCGCAGCCATCAGTCAAATTCGATCTCAGCACAACCAAAacaagcatcagcagcaacaccaccagcagcagcagcatcaacaacagcaaccggcgcagcagcagcagcagcagcaacatatAACCGTACAACATAATGTAAACCTAGCACCACCGAGTGGGAAGCACAGCAAAGCCCACACGGAGATCTTTCTGAATCctccgccaccaccgccgccacaGTCCACGACGATGCCGTCTTCAGCGAGCTCATGTACATCCAGACTGCAgcattcacaacaacaacagcatcagcaccagcatcaacatcagcaatCGCttccagccagcagcagctatgCAGCGCCCACTTGCTCGAGTGCTGCGTCGACCCTGATGGCAGCATCTAGTAGTGGACGAGGCAGCAGTCGCCAGTCGACCAATTCGCCATTTGGTGCACTGCTTAATGCAGCAGCGCAGGCTGCCAGCTCGTCCCCCGCCACTTCCAGCGCCTCAGTGCTGCGCTATGCTGAATCGCCAGTTGCCCACTACCTGGAGCGAGAGAATGGCGATTTTATTGTGCAGGAGACGCCCAAGCATATTGTTGAATGCGTCGAGAAAGATGACGGCGAGTTCTCAGTGATTGAGCGCATCTACCAGTCGCCCCCTAGCGTTTTGCACatacacgacgacgacgaggaagaGGATCTCAGCTGGGCAAACAGCGACGATGAAGATCACGTCAAGTTGACGCACAATCATGTCGAGGATGGCGACGATGAGCGTGAGGACAGCCGCAGTAGAGTTGGCCTtaaaacgacaacaagaaaGTCGCGCAAAACAAAGTCCGGCAGCAGAACACACAAACGTGCGTCCAAGCATCAGTTAGCCGCCGAGGAGGAAGAAGAGTTCATGAGCGTGGGCAGCAGTGAGAACGatgaggaggaagaggaggaagAACAGCACCACcagccgtcgtcgtcagctACAGTGCAAGTGGCGCTGTCTTCGCCGCCGCAACTTTGCACGGCACCATCGACGAGCAGTGGCGCCGCTTCGGTATCCTCTGGCAGTGCCAATGCCTCATCCAGCGGCACCGTCAAGTCCAAAAAGAATCGCATTACAGTGCTGAGCGATGTGCCGCTCAATATGAACGAGTATTTGGATCTGGTGGGCAACATTGTGGCTTCTAGTCGCATTGGTGCCACACGTCCATTTGCCGCTGTCGCACCCATTCCGTTGGTCAAGGTGGAAAAGGAGGAGCCGCTAGACGAATACGATAGCGTGCCGAGCGAGATGCCATCGATAGAGCAGAAGCCCAGCTTGGAGAAtgccgctgccagcagcagtagtagcagcaacagcagcagcaatggacACGGCACCACCAGCGTCATTCGTATGgccagcacgagcagcagtaCCAATGTTCCGGCCGAGGACCTCACCCAGCCGCCGCCAATGAAAGTCGAGGTGGAGCCAACGATGCTGTTGCCGCAACGTTTCTCGGCGCCGGCCCAGCAGCGTGGTCCTAAGAAATTAGTCATCAAACCAAAGGCTtcagcaacggcgacggcatccacatcgacggcgacggcgacagcgacgaaaAAGACTGATAATAATAACGCTgccagcaacaggagcagcaactgcaccGAATCTCTCAGCATATCAAAAACATCGGCCGAACTGGTGCAGGTCAAGAGCGAGACTGTGGAACCGTCCACGTCGGGTAGCAGCATCCTCGAGAAGCATCTCACCACCAGCTATGCCGGCCAGCAATCATCGCGCAAGCACTCCACAGTTAATGATGACGATGCGCGCGTCCTTCTCGAGTTTGCCAACTCCAAACAGTTGCCACTGGCAAGCGGCAGCAATCCCACGACGTTTGTGGTGAATGCGGCAAGTTTCGCATCGGCAGGTTCCGTGTTTGCcagcaacatgcaacagcagcagccaattaAGCCGGGTGACGAGTACATACTGCCCGATGACAGCAAAGTGGAAGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCctccacacagcagcaaccacatcaacagcagcatcagcagcaacaccatcaGTCGTCTGCTGGGGCTGTGCAAGCAGCGCACTCGACACTGCAGCCGCCGAACTTCAATGATTTCAACTTTCTATACCACCAAAATGCAGCAACATCGGCTCCGACTTCCTCCAGCTTTGCGCCCTTCGgtctgcagcaacagcagcagcacggcaCCAGCGAAGCGACCAATGCAGCAACTCTCGCCTCATCCTCCAGCAACTCATCAGCAATGGATCTGGAGTCGTCCATGAATGCATTGTTCCGCATGGCCAAGCCTCAGTCTTCGTTGAGTGGATGGTatcaaccacagcagcaacaacaacaacagcagcagcatcatcatcatcaccaagcacagcaacaacagcagcagcaacctcaGCCAACCACTTCTCAGAATGCGGAGCAGCAGTCaagcaattttattgctgctttggctgctgtcgaTTGCTGCAGCGTGGCGATGGACAGCGATGCGAGTGATGCAAAGTATTTGGATCTGGATACATGCAAGCGGGAACAGTTGAGCAATAGCAGCAGTCATTTGCCCTCAGCGTCAGCGtccacatcaacaacatcgtCCTCGTTTGCTGCGGCCGCCACAGAGAGCAGTCTTGTGGGCGGTCTGGGTTTGAATATCCGGACTGATGAAAAAATGCCTGCCAAGGGTGAAATTTCCGAGCAGGAGAGCAACTGTGACATTGAGAACTCCTGGAGTCAATCGATGTACTTTAGAAGCCAGTTTGCGGAAGGTTACCGGGTGGTGACCGATTGGCGTCAGGACTACTATCCGGCGGAGGATCTCAgtggtcagcagcagcagcgtgagcaCAAGCGATTTGATTTCAATGCGGTGGCATCCGATCATGCGCAGCCGGGTGAGATCGacagctcctccagctcggCGCGTAGCAATCAATTGCTGGATGCACAGCCCACCACCTCGACGTCGTCTTCGGCATTGCTGGCTGGTCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAGGCAGaggctgttgcagctgcattgcaGCGAAAGGGTCAACGGCGTAAGATCTATAGGTGTCCACACTGCGTGGCCATCTTCGAGAAGCTGAAGGAGCGCAATGCCCACATGATTGGAGAGCACAACTATGTGCGCCAGAATCGTCGGCTGATCTGCGCACAGGCGGTGGTCAATGGTGTTATGCTGGCACAGCCGCAGGCTTCAGAGCCACaacaaacgcagcagcagctgttgctgcaggcGGGTGGCAGCAATAACGATGCTCTGCATGAAGACTCCAAGGATGGCATTGTAAAGATCAAGCAGGAGCACTGTCAGGACAAACCCGATTCGTcggagcagcagttgctcgTCCAGTTGGAGCTTCCCGATGTGAAAGATTCCGGCTTGTTGGCGGTCAACAGTGAGAGCGCTAACGATGCAGACGTGAAGCCATCCACGACAGTGACTGATGTGAAGCCGACTATGGCGCCACTCAGTATGACAACACCTGCTGCCAAATTGGCGGCTATTTATCGCATGCTCATTTCCTACAACGAGTCGAAGCTTGGACAGGACCATCACAACCTCAGCGAGCTGGAACAAAAGGCCATGGAGAAATCCATATTTCTGTGCTACGTTTGTCGCACCGACTTTCCCTCGGTGAAGCTGTACGATGCCCATTTAACTGAGCATCCCGCCGAATGTTTCACCTGTGGCAAGAAGTTCTATCGCTGGAAGAATTTCTCACTGCATCTGAAGCGTCATCTAGGCTGGAAGGAGTTCGGCTGCTATGTGTGCGATAAGAAATTTGTGGTGCGCAGTGCTCTCGTCGAACATATGCGCATGCACACGGGCCAAACTCCCCTGAAGTGCAAGATATGCGGCAAAAAGTTCAAACGGTACTCCAACTTGACTCAACATCGGAAGCGTCACACCAAAATGACAGTGCGGAAAAAGGAGTACGTGTGTCATTGCGGCGAGGTGCTGCCATCGAAGGCACGCTTCCTGTGGCACAAGGAGACGCACGATCTAAAGCCCAAATGCTGTCCGTATTGCTGTGATCGTTTTGTACACGCCAATTCACTACGTCGCCACATTCGTCTGGCCCATTCGGACAAGTTTGATTACGCCGAGCCTATGGAGTGTCCCATGTGCAAGCAGATATTTGCGAAAACGTCCATCAAGGCGCACATGGCGACGCACTCAACGGACCCACAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCACGCCAATCGCACTGCCAAACCGTTCAAGTGCGAGTACTGTCCCAAGGCTTTTGTGCGCGAACTGGACTTTAAGAATCACATGAATGCGCACAAGCAGATCAAGCCCTACACATGTGAGTATTGTGGTTGTAAGTTCATACGCAAGTACAATTACATGCGGCATCGGCGGGAGCACCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAATCTTTCCATCGGCACTACTATTTGATTGAGCATCGGCGAATCCACACGGGCGAGCGGCCTTTCCACTGCACCATCTGCGGCAAAAGCTCCACCACGAAGACCAATCACAATAAGCATCTGAAGATACACCATTCGCGCGATCCCTTTACCGTGGAGGTCTAA
- Protein Sequence
- MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNNPMGCSLAAAAALATAGSGSQTAAASLDGAASSTAPEADVKPAVAAPPAAPTPPAPAPATQTSAAAAATTANATATTTPSTLKSAAPKAASLLGNANANANINSSSSSGSSSNSGSSSNSNNNKLSNPPIKAVKSAPPSTEASATTSNTPTISSVAAAYPPSLTPDCRYDQQQQQQQQQHQAQQQATPAATLHGFPRGATTMLVIPQATQHQHHFLATHTAHFTHQQQQQQQQSPMKYTYATTLPPPPPPLQLFAQQPTSTQSHQKPPPAYGAAISQIRSQHNQNKHQQQHHQQQQHQQQQPAQQQQQQQHITVQHNVNLAPPSGKHSKAHTEIFLNPPPPPPPQSTTMPSSASSCTSRLQHSQQQQHQHQHQHQQSLPASSSYAAPTCSSAASTLMAASSSGRGSSRQSTNSPFGALLNAAAQAASSSPATSSASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEDLSWANSDDEDHVKLTHNHVEDGDDEREDSRSRVGLKTTTRKSRKTKSGSRTHKRASKHQLAAEEEEEFMSVGSSENDEEEEEEEQHHQPSSSATVQVALSSPPQLCTAPSTSSGAASVSSGSANASSSGTVKSKKNRITVLSDVPLNMNEYLDLVGNIVASSRIGATRPFAAVAPIPLVKVEKEEPLDEYDSVPSEMPSIEQKPSLENAAASSSSSSNSSSNGHGTTSVIRMASTSSSTNVPAEDLTQPPPMKVEVEPTMLLPQRFSAPAQQRGPKKLVIKPKASATATASTSTATATATKKTDNNNAASNRSSNCTESLSISKTSAELVQVKSETVEPSTSGSSILEKHLTTSYAGQQSSRKHSTVNDDDARVLLEFANSKQLPLASGSNPTTFVVNAASFASAGSVFASNMQQQQPIKPGDEYILPDDSKVEVDEIVISSSSSFASSTQQQPHQQQHQQQHHQSSAGAVQAAHSTLQPPNFNDFNFLYHQNAATSAPTSSSFAPFGLQQQQQHGTSEATNAATLASSSSNSSAMDLESSMNALFRMAKPQSSLSGWYQPQQQQQQQQQHHHHHQAQQQQQQQPQPTTSQNAEQQSSNFIAALAAVDCCSVAMDSDASDAKYLDLDTCKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYFRSQFAEGYRVVTDWRQDYYPAEDLSGQQQQREHKRFDFNAVASDHAQPGEIDSSSSSARSNQLLDAQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKGQRRKIYRCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICAQAVVNGVMLAQPQASEPQQTQQQLLLQAGGSNNDALHEDSKDGIVKIKQEHCQDKPDSSEQQLLVQLELPDVKDSGLLAVNSESANDADVKPSTTVTDVKPTMAPLSMTTPAAKLAAIYRMLISYNESKLGQDHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00537699;
- 90% Identity
- -
- 80% Identity
- -