Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000117.1:2228521-2234978[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.049 3.7 8.4 0.2 1 23 1301 1324 1301 1324 0.94

2 13 7.9 6.1e+02 1.4 0.2 1 23 1486 1508 1486 1508 0.91

3 13 0.00018 0.014 16.0 2.7 2 23 1511 1532 1511 1532 0.97

4 13 6.8e-05 0.0052 17.3 0.2 3 23 1540 1560 1538 1560 0.98

5 13 5.7e-07 4.3e-05 23.9 4.1 2 23 1567 1588 1566 1588 0.97

6 13 5.1 3.9e+02 2.0 0.4 5 23 1601 1619 1598 1619 0.95

7 13 1.3 1e+02 3.8 5.4 3 23 1626 1647 1624 1647 0.93

8 13 0.14 11 6.9 0.2 2 23 1658 1678 1657 1678 0.96

9 13 5.4e-05 0.0042 17.7 0.4 1 19 1684 1702 1684 1706 0.95

10 13 1.6e-05 0.0012 19.4 0.5 1 23 1714 1736 1714 1736 0.98

11 13 0.0001 0.0078 16.8 7.6 1 23 1742 1764 1742 1765 0.96

12 13 0.0002 0.015 15.9 5.9 1 23 1770 1792 1770 1792 0.98

13 13 0.028 2.2 9.1 8.2 1 23 1798 1820 1798 1821 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.049	3.7	8.4	0.2	1	23	1301	1324	1301	1324	0.94
2	13	7.9	6.1e+02	1.4	0.2	1	23	1486	1508	1486	1508	0.91
3	13	0.00018	0.014	16.0	2.7	2	23	1511	1532	1511	1532	0.97
4	13	6.8e-05	0.0052	17.3	0.2	3	23	1540	1560	1538	1560	0.98
5	13	5.7e-07	4.3e-05	23.9	4.1	2	23	1567	1588	1566	1588	0.97
6	13	5.1	3.9e+02	2.0	0.4	5	23	1601	1619	1598	1619	0.95
7	13	1.3	1e+02	3.8	5.4	3	23	1626	1647	1624	1647	0.93
8	13	0.14	11	6.9	0.2	2	23	1658	1678	1657	1678	0.96
9	13	5.4e-05	0.0042	17.7	0.4	1	19	1684	1702	1684	1706	0.95
10	13	1.6e-05	0.0012	19.4	0.5	1	23	1714	1736	1714	1736	0.98
11	13	0.0001	0.0078	16.8	7.6	1	23	1742	1764	1742	1765	0.96
12	13	0.0002	0.015	15.9	5.9	1	23	1770	1792	1770	1792	0.98
13	13	0.028	2.2	9.1	8.2	1	23	1798	1820	1798	1821	0.95

Sequence Information

Coding Sequence: ATGGTTGACAGtgtgcagtgccccgtgtgcACCTTGTACTTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACCCATCCCAAGGAACAAGTGATCAAAGCCCTGGTGCAAATGACAATCGCTGGCAACAATGCATTGGGCGGCGCCCTGGTGGCAGCTGCACTCTCCACTGCCGGCAGTGGTGCATCATCAGACAGCGCCGCCTCCTCCTCTTCCCCAGCAGCGCCAGATTCAGATGTGAAACcagttgtggcagcaacagcaacagtagctacagcagcagcaccaacgcCACCATCACCACCACAGccaccaataacaacagcaacattaaaGTCAACTGCACCCAAGGCAGCATCATTGCTGGGAAAtacaagtaacaacaacaacagcagtaacagtagcaacagtaacaataacaaattgagCAATCCACCGATTAAGGCAGTTAAAAGCGCGCCAACCTCGACTGAGGCGTCAGCCACCACATCCAACACACCCACCATAAGCAGCGCAGCCGCTGCCTATCCTCCATCGTTGACATCCGACTATCGCTAtgatcagcagcaacagcagccacaacaacagcagcaacagcaacaggcgaCGCCAACGGCAACGCTTCATGGCTTTCCACGTGGAGCAACCACAATGCTAGTGATACCACatgcaccacaacaacagcagcatcattTCCTGGCCACCCAACCACCGCCTGGTCATTTTAcccatcagcagcaacagcaccagcaaaCACAGTCGGCTTTGAAATACACGTATGCAACTACgttgccaccaccaccgccgcctcTGCAGCTCTTTGCACAGCAGCCGACGACTTCGCAGTCACATCAGAAGCCACCGCCCGCCTATGGCGCAGCCATCAGTCAAATTCGATCTCAGCACAACcaaaacaagcaacagcagcaacaacaacatataacCCTGCAACATAACGTTAACCAAGCACCACCGAGTGGGAAGCACAGCAAAACCCTTACGGAGATTTTTCTGAATCCACCGCCTCCACCACCGCCACAGTCGACCTCCTCTGCACCCGCATCCTCCTCCTCAAGACTGCAACATccacaacagcatcagcaatcCCTTACAGCCGGCAGCAGCTACACTCCAGCTAGTTGTTCCAGCTCCTCATCGAGCCTGTTGTCATCGACAAGCGGACGAGCCAGCAGTCGTCAAACGACAAATTCGCCATTTGGTGCACTGCTTAATGCGGCGGCACAAGCTGCCAGTTCCTCGCCCGCCTCCACTAGCGCATCTGTGTTGCGTTACGCCGAATCGCCGGTTGCCCACTATCTGGAGCGGGATAATGGTGACTTCATTGTCCAAGAAACGCCCAAACACATTGTGGAGTGTGTCGAGAAAGATGATGGAGAGTTCTCGGTCATTGAGCGCATCTATCAGTCGCCACCCAGCGTGTTGCACATACACGACGATGACGAAGATGAGGAGGAACAAAGCTGGGCAAACAGCGAAGATGAGGATCACGCAAAGGCGGATAATAATGTGGAGGATGGCGATGACGAGCGTGAGGACAGTATCAGCAGAGTTGGCCTTAAGACAACAACGAAAAAGTCGCGTAAAACCAAATCGAGTGGCAGAATGCACAAACGCGCGTCTAAACATCAGATAACCACTACGGAGGATGAGGAAGAGTTCATGAGTCTGGGCAGCAGTGAGAACGAAGATCAGGCAGAGGAAGAACTGCAGTCTTTAGGTGATGCACAGGTGGCATCACCAACTCCTCCACAACTTTCCACGGCGCCTTCTACGAGCAATGGGGCAGCTGCGGCTGCAGTAGCTGCTGGCAATGTCAGCTCCACGTCGAGCGGTACCATCAAGTCGAAAAAGAATCGCGTTACAGTTCTGAGCGATGTGCCGCTTAATATGAATGAGTATCTGGATCTGGTGGGCAACATTGTGGCATCCAGTCGCATTGGGGCAGCTCGTCCATTTGCCGCTGTGGCACCCATCCCCTTGGTCAAGGTGGAAAAGGAGGAACCGCTGGACGAGTATGACAGCGTTCAGAACGAGATGCAATCTGTGGAACAAAAGCCCAGCCTAGAACATGCCAGTggcagcagtagcagtagtagcagcagcagtagcagcaatgGACATGGCACCACCAGCGTCATTCGGATGGCCAGCACAAGCAGTAGTACCAATGTTCCGCCCGAGGATCTCACACAGCCGCCGCCAATGAAAGTTGAGGTAGAGCCAAcgatgttgttgccacaacgCTTCTCAGCACCGGCTCAGCAGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACAGCAACGGCGACtgcaacgacgacgacgacgactttGAAAAAGACTGATAATAATGCTGCCGGCGTCAGCGTCAGAAGCAACAACTGCGCTGAATCTCTTAGCATATCAAAGGCATCTGCAGAACTGGTGCAGGTCAAGAGCGAAAATGTGGAACCGTCCACATCGAGTGGTAGCATTCTAGAGAAGCATCTGACCACCAGCTATATTGGTCAACAAGCACGCAAACACTCCACAgtcaatgatgatgatgctcgTGTGTTGCTTGAATTTGCCAACTCGAAACAAATACCATTggcaggcagcagcagcaatcccACAACATTTGTGGTGAATGCGGCCAGTTTTGCATCGGCAGGATCCGTATTTGCCAGCAACATGCAGAAGCCAATCAAACCGGGTGACGAGTACATTTTGCCAGATGATAACAAAGTGGAAATTGATGAAATTGTGATATCCTCTTCGTCTTCCTTTGCCTCCTCCACGCAGCAaccgccgcagcagcagcagcagcatcaacaccATCATCAGGCAACTTTGGCAGTTCAAGCCCAGCACTCGACGTTACAACAGACACAGCCACCTACGTTTAATGACTTTAACTTTCTGTACCAccaaaatgcaacagcaacaacgacaccGACGGCTTCCAGCTTTACGCCGTTCGGTcttcagcaacagcagcaacaacaacaacacggtTCTAGCGAAGCCACAAACGCAGCGACACTCGCCTCGTCCTCGAGTAACTCGTCAGCATTGGATCACGACTCCTCCATGAATGCAACGTTCCGCGTGGCCAAACCGCAGTCATCACTGAATGCCTGGTATCAGccacagcatcaacagcaacaggaacaacagcaTCCACAGCCAACAACCTCCCAGAACGTGGAACAGTCGAGCAATTTTATTGCAGCATTGGCAGCCGTCGATTGTTGCAGTGTGGCGATGGACAGTGATGCAAGTGATGCCAAGTACTTGGATTTGGATGCATGCAAACGGGAACAGTTgagcaatagcagcagccaTTTGCCCTCTGCTTCGGCATCCACGTCCACAACATCCTCTTCATTTGCTGCTGCAGCCACAGAAAGCAGCCTCGTTGGTGGCCTGGGATTGAACATTCGGACGGATGAGAAGATGCCTGCCAAAGGGGAAATATCCGAGCAGGAGAGCAACTGCGACATTGAGAACTCCTGGAGTCAATCGATGTATGGAGACATATCACAGCGGTACTTTAGAAACCAGTTCGCGGATGGTTACAACAATCAACAGCTGACCGATTGGCGTCAGGACTATTATCCTGCGCAGGATCTCAGTggtcagcagcaacagcgagaGCACAAACGTTTTGACTTTAATGCGGTCGCCTCCGAGTACGCGCAGCCAGGTGAACTGGACGCCTCTTCGGGCTCTGCAAGGAGCAATCATTTGCTAGATGTGCAACCCACCACGTCCACGTCGTCTTCGGCTTTGCTGGCTGGCCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAAGCGGAGGCAGTCGCTGCAGCGTTGCAACGAAAACCCGCACGTCGAAAGATCTACAAGTGCCCACACTGTGTGGCCATCTTTGAGAAGCTAAAGGAGCGCAACGCACACATGATTGGAGAGCACAACTATGTGCGGCAGAATCGCCGACTCATTTGTACGCAAGCATTGGTCAATGCTGCCATGTTAGCACAGCCGCAGgttcaacaacagcagcagcaacaacaacaacaactgttgctgcagccAGGTGGAAGCATTAGCGAAGCTTTGCAGGAAGATTCCAAGGATGGCATTGTAAAGATCAAACAGGAGCAGTGCCAGGACAAGCCCGATTCATCGGAGCAGCTGCTTGATCACTTGGAGCTGCCGGATGTGAAAGATGCAGTCTTGTTAGACGTTAACGCTGAGAACCGACCTGATGCGGACGTGAAACCTTCCACCAACGTGGCTGATCTGAAGCCGACCCTGGCGCCCTTGGCAATGACCACACCGGCTGCCAAGTTGGCAGCTATTTATCGGATGCTTATTGCCTATAATGAATCAAAGCTTGGACAGGAGCATCACAACCTCAGCGAGCTGGAGCAAAAGGCCATGGAGAAGTCCATATTTCTATGCTACGTCTGTCGCACCGATTTCCCCTCTGTTAAGCTTTACGATGCACATCTCACAGAGCATCCCGCCGAATGCTTCACCTGTGGCAAGAAATTCTATCGCTGGAAAAACTTCTCACTGCATCTGAAACGTCATCTTGGCTGGAAGGAGTTCGGCTGCTATGTCTGCGATAAGAAATTCGTTGTGCGCAGTGCCCTCGTCGAGCACATGCGCATGCATACTGGCCAAACCCCGTTGAAGTGTAAGATATGCGGCAAAAAGTTCAAGCGTTACTCCAACTTGACTCAGCATCGGAAGCGTCACACCAAAATGACGGTGCGGAAAAAGGAATATGTGTGTCACTGTGGCGAGGTGTTGCCGTCGAAGGCTCGTTTCCTGTGGCATAAGGAAACGCACGATTTGAAGCCCAAGTGCTGTCCGTACTGCTGCGATCGTTTTGTGCATGCCAATTCACTGCGACGTCATATTAGGCTGGCACATTCGGACAAGTTTGACTATGCTGAGCCCATGGAATGCCCCATGTGCAAGCAGATTTTTGCCAAAACGTCCATCAAGGCACACATGGCAACGCACTCGACGGATCCGCAATATGATTGCGCCATCTGCAACAAGAGCTTCTCCACAAAATGGAATCTTAAGATACATTCGTGGGTGCACGCCAATCGCACCGCCAAACCGTTCAAGTGCGAGTATTGCCCCAAGGCCTTTGTACGCGAACTGGACTTTAAGAACCACATGAATGCGCACAAACAGATAAAGCCCTATACCTGCGAGTATTGTGGTTGCAAGTTCATACGTAAATACAATTACATGCGGCATCGACGGGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAATCTTTCCATCGACACTACTATCTGATTGAGCATCGTCGCATTCACACTGGCGAACGGCCTTTCCACTGTACCATCTGCGGCAAGAGTTCGACCACAAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGAGATCCCTTCACGGTGGAGGTCTAA
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIAGNNALGGALVAAALSTAGSGASSDSAASSSSPAAPDSDVKPVVAATATVATAAAPTPPSPPQPPITTATLKSTAPKAASLLGNTSNNNNSSNSSNSNNNKLSNPPIKAVKSAPTSTEASATTSNTPTISSAAAAYPPSLTSDYRYDQQQQQPQQQQQQQQATPTATLHGFPRGATTMLVIPHAPQQQQHHFLATQPPPGHFTHQQQQHQQTQSALKYTYATTLPPPPPPLQLFAQQPTTSQSHQKPPPAYGAAISQIRSQHNQNKQQQQQQHITLQHNVNQAPPSGKHSKTLTEIFLNPPPPPPPQSTSSAPASSSSRLQHPQQHQQSLTAGSSYTPASCSSSSSSLLSSTSGRASSRQTTNSPFGALLNAAAQAASSSPASTSASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEDEEEQSWANSEDEDHAKADNNVEDGDDEREDSISRVGLKTTTKKSRKTKSSGRMHKRASKHQITTTEDEEEFMSLGSSENEDQAEEELQSLGDAQVASPTPPQLSTAPSTSNGAAAAAVAAGNVSSTSSGTIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDEYDSVQNEMQSVEQKPSLEHASGSSSSSSSSSSSNGHGTTSVIRMASTSSSTNVPPEDLTQPPPMKVEVEPTMLLPQRFSAPAQQRGPKKLVIKPKATATATATTTTTTLKKTDNNAAGVSVRSNNCAESLSISKASAELVQVKSENVEPSTSSGSILEKHLTTSYIGQQARKHSTVNDDDARVLLEFANSKQIPLAGSSSNPTTFVVNAASFASAGSVFASNMQKPIKPGDEYILPDDNKVEIDEIVISSSSSFASSTQQPPQQQQQHQHHHQATLAVQAQHSTLQQTQPPTFNDFNFLYHQNATATTTPTASSFTPFGLQQQQQQQQHGSSEATNAATLASSSSNSSALDHDSSMNATFRVAKPQSSLNAWYQPQHQQQQEQQHPQPTTSQNVEQSSNFIAALAAVDCCSVAMDSDASDAKYLDLDACKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFADGYNNQQLTDWRQDYYPAQDLSGQQQQREHKRFDFNAVASEYAQPGELDASSGSARSNHLLDVQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNAAMLAQPQVQQQQQQQQQQLLLQPGGSISEALQEDSKDGIVKIKQEQCQDKPDSSEQLLDHLELPDVKDAVLLDVNAENRPDADVKPSTNVADLKPTLAPLAMTTPAAKLAAIYRMLIAYNESKLGQEHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537699;
90% Identity: iTF_00583886; iTF_00608633;
80% Identity: -