Dust011290.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila ustulata
Gene Symbol
-
Assembly
GCA_035047365.1
Location
JAWNPT010000094.1:17147017-17153503[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.065 4.4 8.0 0.2 1 23 1346 1369 1346 1369 0.94
2 13 8.2 5.5e+02 1.4 0.2 1 23 1532 1554 1532 1554 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1557 1578 1557 1578 0.97
4 13 7.1e-05 0.0048 17.3 0.2 3 23 1586 1606 1584 1606 0.98
5 13 5.9e-07 4e-05 23.9 4.1 2 23 1613 1634 1612 1634 0.97
6 13 5.6 3.8e+02 1.9 0.4 5 23 1647 1665 1645 1665 0.96
7 13 1.4 93 3.8 5.4 3 23 1672 1693 1670 1693 0.93
8 13 0.15 9.9 6.9 0.2 2 23 1704 1724 1703 1724 0.96
9 13 5.6e-05 0.0038 17.6 0.4 1 19 1730 1748 1730 1752 0.95
10 13 2.6e-05 0.0018 18.7 1.4 1 23 1760 1782 1760 1782 0.98
11 13 0.00011 0.0071 16.8 7.6 1 23 1788 1810 1788 1811 0.96
12 13 0.00026 0.017 15.6 6.1 1 23 1816 1838 1816 1838 0.98
13 13 0.029 2 9.1 8.2 1 23 1844 1866 1844 1867 0.95

Sequence Information

Coding Sequence
atggtGGACAACAGCGTGCAGTGTCCCGTGTGCACTTTGTACCTGCATGCGGGCATGAATCTCTCGGATCATTTGGAGACGCATCCCAAGGAGCAGGTGATCAAGGCGCTGGTGCAAATGACAATCGTTGGCAACAACCCCATGGGCTGCTCgctggcggcggcagctgcgcTTGCCACTGCCGGCAGTGGCAAACAAACAGCGGTGGCAGCGTCAGACGTTGCcgcttcctcctcctcctcctcctcgtcatCTTCCGCAAAAGCGGCCGATGCTGACGTGAAACCAGCTgtggcaacaacgacagcgatacccacaacaccagcagcagcagcaactgcaacgcaAACAGCcccagcgacagcaacagcagcagcagcaaatacattcaaatcaacagcagccaaagcTGCCCCATTGCTGGGCAATGCGAACGCCAacacaagcagcaacagcaacaataacaaattgagCAATCCACCGATTAAGGCAGTCAAAAGCGCGCCACCCTCGACTGAGGCATCAGCCAGCACATCCAACAACACACCCACCATAAGCAGCGTGGCCGCCGCCTATCCGCCCTCCTTGACATCCGACTATCGCTacgatcagcagcagcaacagcagcagccccaacaacaacagcagcagcagcaacaacaggcgaCGCCAACAGGAGCAACACTTCATGGCTTTCCACGTGGTGCTACCACAATGCTGGTGATACCGCAGGCTGGGCAACAGCATCAGTTTCTGGCAACGCAGCCCGCTCACTttgcccagcagcaacagtcgcccATGAAGTACACGTATGCCACCGCCACGCTGCCaccgccgccaccaccgcTACAGCTCTTTACACAGCAGCTGACGACAGCGCTGTCGCATCAAAAGCCACCGCCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCACAACCaaaacaagcagcaacaacagcagcaacagcatccacaacaacagcaacagcaaccacagcagcaacagccacataTAAGCGTACAACATAATGTTAATCTAGCACCACCGAATGGCAAGCACAGCAAAGCCCACACGGAGATCTTTCTGAATCCTCCGCCACCACCACCGACGATGCCGTCGTCATCTtccacatcatcatcaacgaCCTCCTGCGCCTCCAGACTGCAaccacaacatcaacaacaacatcctcACCAGCAATCGCTTCCAGCCAGCAGTAGCTTTGCAGCCACCAACTGCTCCAGCGGCCAAGCGTCGAGTGCCAGTCGAGGCAGCAGTCGCCAGTCGACCAATTCACCATTTGGTGCACTGTTGAATGCAGCAGCGCAGGCTGCCAGCTCATCGCCCGCCTCCTCCAGCGCCTCGGTGCTGCGCTATGCCGAATCGCCTGTGGCGCACTATCTGGAGCGGGAGAATGGTGACTTTATAGTGCAAGAGACGCCCAAGCACATTGTCGAGTGCGTGGAGAAGGATGACGGCGAGTTCTCGGTGATTGAACGCATCTATCAGTCACCGCCTAGCGTCCTGCATATacacgacgacgatgatgaggaGGATCAGAgCTGGGCAAACAGTGAAGATGAAGATCACGTCAAGGTGGAGCATAATCATGTCGAGGATGGCGACGATGAACGCGAGGACAGTCGCAGCCGAGTTGGCCTCAAAACAACAACGCGAAAGTCACGCAAAACCAAACCGGGCAATCGAATGCACAAACGTGCCTCCAAGCATCAGTTGGCCgtcgaggaggaggaagagtTCATGAGCGTGGGCAGCAGCGACAATGAAGATGTGGAAGAAGACGAGGAGCATCATCATCACAATCATCAGCAGTCGCCATCGGCTGCTGTGCAGGTCGCGTTGTCTTCGTCGCCACAGCTTTGCACGGCACCGTCGACGAGCAGCGGAGCCGCGTCGTCCGCCTTCGCTGGCATTACGAATGCCACGTCCAGCAGCACCGTCAAGTCCAAAAAGAACCGCGTCACAGTCCTTAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATTTGGTGGGCAATATTGTGGCTTCGAGTCGCATTGGTGCCACGCGTCCATTTGCCGCCGTTGCGCCCATTCCGCTGGTCAAGGTCGAGAAGGAGGAGCCGCTGGACGAATACGACAGCGTGCCGAGCGGCGAGTTGCCAGTGATGGAACAGAAGCCCAGCTTGGAGAATGccgccggcagcagcagcagtaacagcagcagcaatggacACGGCGCAACCAGCGTCATACGCATGGCCACCACCAGCTCCGCCAATGCCAATGTTCCGGCCGAGGATCTCACACAGCCGCCGCCCATGAAGGTCGAGGTGGAGCCAACGATGCTGTTGCCGCAACGCTTCTCGGCGCCAGCCCAGCAACGTGGTCCCAAGAAATTAGTCATCAAACCAAAGGCCACAGCatcggcaacggcaacgacagcagcgacggcgacgaaaAAGACTGATAACAACTGCGCCGAATCTCTCAGCATATCAAAAACATCGGCCGAACTGGTGCAAATCAAAAGCGAGACCGTCGAACCGTCCACCTCGAGTGGCGGCAGCATCCTCGAGAAGCATCTGACCACCAGTTATGCGGGGCAACAATCAGCGCGCAAACACTCCACAgtcaacgacgacgatgcgCGCGTCCTGCTCGAGTTTGCCAACTCCAAACAGTTACCActggcaagtggcagcaaTCCCACCACGTTTGTGGTGAATGCCGCAAGCTTTGCCTCGGCCGGATCCGTGTTTGCCAGCaactcgcagcagcagcagcaacagaagccgGGTGACGAGTACATACTGCCTGATGACAACAAAGTGGAAGTGGATGAAATTGTGATATCCTCGTCGTCTTCCTTTGCCTCCGCCacacagcagccgcaacagcagcaccaccagcatcaacagcaacaacatcaacagcagcatcatcaacaacatgcAACTGCTGCGACAGTGCAGGCAGCGAACTCAACATTGCAGCAGACACAGCCACCAAACTTCAATGATTTCAACTTTCTGTATCAtcaaaatgcaacaacaacaacggcagcaacatccTCCAGCTTTGCGCCTTTCGGCctgcagcaacatcatcagcagccaCAACACGGTTCCAGCGAAGCAACCAATGCAGCAACGCTCGCCTCATCCTCCAGCAACTCGTCAGCCATGGATCACGAGTCATCCATGAATGCATCGTTCCGAGTGGCCAAATCGCAGTCAACGTTGAGTGCGTGGTatcaaccacagcagcaacaacaacagcagcagcatcatcttcaccaacaacagcagcaaccgcagCCAACAACTTCTCAGAATGTGGAGCAATCAAGTAATTTTATTGCTGCCTTGGCGGCTGTCGATTGTTGCAGTGTCGCGATGGACAGCGATGCGAGCGATGCCAAGTATTTGGATCTGGACACATGCAAGCGGGAGCAGttgagcaacagcagcagtcatTTGCCCTCGGCATCGGCATCTACATCGACAACATCATCCTCATTTGCAGCGGCTGCCACAGAGAGCAGTCTAGTTGGTGGTCTGGGCTTGAATATACGCACCGACGAGAAGATGCCCGCCAAGGGAGAAATTTCCGAGCAGGAGAGCAACTGCGACATTGAAAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGATACTTTAGAAGCCAGTTTGCGGATGGTTACAATCAACAGCTGTCCGAATGGCGTCAGGACTATTATCCGGTGCAGGATCTTAgtggccagcaacagcagcagcagcgtgagCACAAACGATTTGATTTCAATGCGGTGGCATCCGAGTATGCGCAGCCGGGTGAACTGGACGCCTCCTCGAGCTCGGCGCGTAGCAATCAATTGCTGGATGCACAGCCCACCACCTCGACGTCGTCATCGGCTTTGCTGGCTGGTCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAAGCAGAGGCCGTTGCAGCTGCATTGCAGCGCAAGGGTCAACGCCGCAAGATCTACAGGTGTCCACACTGTGTGGCCATTTTCGAGAAGCTCAAGGATCGCAATGCCCATATGATTGGCGAGCATAACTATGTGCGCCAGAACCGTCGACTCATCTGCACCCAGGCATTGGTTAATGGTGCTATACTGGCACAGCCCCAGGTTCTACAaccaccgcagcagcagcaagaattGTTGCTGCAACCAGGCGGCAGCAATAGCGAAGTTGTGCATGAAGATTCCAAGGATGGCATTGTTAAGATCAAACAGGAGCACTGTCAGGACAAGCCTGATTCAACGGATCAGCAGCTGCTCGTGCATTTGGAACTGCCCGATGTAAAAGATGCCGGTTTATTGGCCGTCAATGGTGAAAACGCTAGCGATGCAGACGTGAAGCCATCAACGAACGTGACGACGGATCTGAAGCCCACCATAACGCCGCTGAGCATGACAACACCGGCTGCCAAATTGGCGGCTATTTATCGCATGCTCATTTCCTACAACGAGTCAAAGCTGGGCCAGGACCATCATAATCTCAGCGAACTGGAGCAGAAGGCAATGGAGAAATCCATATTTCTGTGCTACGTGTGTCGCACCGACTTTCCCTCGGTGAAGTTGTACGATGCCCATTTAACTGAGCATCCCGCCGAATGCTTTACCTGCGGCAAGAAATTCTATCGCTGGAAGAACTTCTCACTGCATCTAAAACGTCACCTTGGCTGGAAGGAGTTCGGTTGCTATGTCTGCGATAAGAAATTCGTGGTGCGCAGTGCTCTCGTGGAGCATATGCGCATGCATACGGGCCAAACTCCCTTGAAGTGCAAGATATGCGGCAAAAAGTTCAAACGCTACTCCAACTTGACTCAGCATCGGAAGCGTCACACCAAAATGACCGTACGTAAAAAGGAGTATGTGTGTCATTGCGGCGAGGTGTTGCCATCAAAGGCACGCTTCCTATGGCACAAGGAAACGCACGACTTGAAGCCCAAATGCTGTCCGTACTGCTGTGATCGTTTTGTGCACGCCAATTCATTGCGTCGACACATTCGGCTGGCCCATTCGGACAAGTTCGATTACGCCGAACCCATGGAATGTCCCATGTgcaagcaaatatttgcgaaAACGTCCATTAAGGCGCACATGGCGACGCATTCAACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCACGCCAATCGCACTGCCAAACCGTTCAAGTGCGAACACTGTCCCAAGGCGTTTGTACGCGAACTGGACTTTAAGAATCACATGAATGCGCACAAACAGATCAAACCGTACACATGTGAGTATTGTGGTTGTAAGTTCATACGCAAATACAATTATATGCGGCATCGGCGAGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAGACTTTCCATCGGCACTACTATTTGATTGAGCATCGACGAATTCACACGGGCGAGCGACCTTTCCACTGCACCATCTGCGGCAAAAGCTCCACCACGAAGACCAATCACAATAAGCATCTGAAGATACATCATTCGCGTGATCCCTTTACCGTGGAGGTCTAA
Protein Sequence
MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNNPMGCSLAAAAALATAGSGKQTAVAASDVAASSSSSSSSSSAKAADADVKPAVATTTAIPTTPAAAATATQTAPATATAAAANTFKSTAAKAAPLLGNANANTSSNSNNNKLSNPPIKAVKSAPPSTEASASTSNNTPTISSVAAAYPPSLTSDYRYDQQQQQQQPQQQQQQQQQQATPTGATLHGFPRGATTMLVIPQAGQQHQFLATQPAHFAQQQQSPMKYTYATATLPPPPPPLQLFTQQLTTALSHQKPPPAYGAAISQIRSQHNQNKQQQQQQQHPQQQQQQPQQQQPHISVQHNVNLAPPNGKHSKAHTEIFLNPPPPPPTMPSSSSTSSSTTSCASRLQPQHQQQHPHQQSLPASSSFAATNCSSGQASSASRGSSRQSTNSPFGALLNAAAQAASSSPASSSASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDDEEDQSWANSEDEDHVKVEHNHVEDGDDEREDSRSRVGLKTTTRKSRKTKPGNRMHKRASKHQLAVEEEEEFMSVGSSDNEDVEEDEEHHHHNHQQSPSAAVQVALSSSPQLCTAPSTSSGAASSAFAGITNATSSSTVKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGATRPFAAVAPIPLVKVEKEEPLDEYDSVPSGELPVMEQKPSLENAAGSSSSNSSSNGHGATSVIRMATTSSANANVPAEDLTQPPPMKVEVEPTMLLPQRFSAPAQQRGPKKLVIKPKATASATATTAATATKKTDNNCAESLSISKTSAELVQIKSETVEPSTSSGGSILEKHLTTSYAGQQSARKHSTVNDDDARVLLEFANSKQLPLASGSNPTTFVVNAASFASAGSVFASNSQQQQQQKPGDEYILPDDNKVEVDEIVISSSSSFASATQQPQQQHHQHQQQQHQQQHHQQHATAATVQAANSTLQQTQPPNFNDFNFLYHQNATTTTAATSSSFAPFGLQQHHQQPQHGSSEATNAATLASSSSNSSAMDHESSMNASFRVAKSQSTLSAWYQPQQQQQQQQHHLHQQQQQPQPTTSQNVEQSSNFIAALAAVDCCSVAMDSDASDAKYLDLDTCKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRSQFADGYNQQLSEWRQDYYPVQDLSGQQQQQQREHKRFDFNAVASEYAQPGELDASSSSARSNQLLDAQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKGQRRKIYRCPHCVAIFEKLKDRNAHMIGEHNYVRQNRRLICTQALVNGAILAQPQVLQPPQQQQELLLQPGGSNSEVVHEDSKDGIVKIKQEHCQDKPDSTDQQLLVHLELPDVKDAGLLAVNGENASDADVKPSTNVTTDLKPTITPLSMTTPAAKLAAIYRMLISYNESKLGQDHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKTFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00537699;
90% Identity
iTF_00509314;
80% Identity
-