Basic Information

Insect: Drosophila niveifrons
Gene Symbol: -
Assembly: GCA_035046325.1
Location: JAWNOC010000046.1:16243979-16250074[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.073 4.8 7.8 0.2 1 23 1398 1421 1398 1421 0.94

2 13 8.2 5.3e+02 1.3 0.2 1 23 1586 1608 1586 1608 0.91

3 13 0.00018 0.012 16.0 2.7 2 23 1611 1632 1611 1632 0.97

4 13 7.1e-05 0.0046 17.3 0.2 3 23 1640 1660 1638 1660 0.98

5 13 5.9e-07 3.8e-05 23.8 4.1 2 23 1667 1688 1666 1688 0.97

6 13 5.6 3.6e+02 1.9 0.4 5 23 1701 1719 1699 1719 0.96

7 13 1.4 90 3.8 5.4 3 23 1726 1747 1724 1747 0.93

8 13 0.15 9.6 6.8 0.2 2 23 1758 1778 1757 1778 0.96

9 13 5.7e-05 0.0037 17.6 0.4 1 19 1784 1802 1784 1806 0.95

10 13 2.7e-05 0.0017 18.6 1.4 1 23 1814 1836 1814 1836 0.98

11 13 0.00011 0.0069 16.7 7.6 1 23 1842 1864 1842 1865 0.96

12 13 0.00026 0.017 15.5 6.1 1 23 1870 1892 1870 1892 0.98

13 13 0.029 1.9 9.0 8.2 1 23 1898 1920 1898 1921 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.073	4.8	7.8	0.2	1	23	1398	1421	1398	1421	0.94
2	13	8.2	5.3e+02	1.3	0.2	1	23	1586	1608	1586	1608	0.91
3	13	0.00018	0.012	16.0	2.7	2	23	1611	1632	1611	1632	0.97
4	13	7.1e-05	0.0046	17.3	0.2	3	23	1640	1660	1638	1660	0.98
5	13	5.9e-07	3.8e-05	23.8	4.1	2	23	1667	1688	1666	1688	0.97
6	13	5.6	3.6e+02	1.9	0.4	5	23	1701	1719	1699	1719	0.96
7	13	1.4	90	3.8	5.4	3	23	1726	1747	1724	1747	0.93
8	13	0.15	9.6	6.8	0.2	2	23	1758	1778	1757	1778	0.96
9	13	5.7e-05	0.0037	17.6	0.4	1	19	1784	1802	1784	1806	0.95
10	13	2.7e-05	0.0017	18.6	1.4	1	23	1814	1836	1814	1836	0.98
11	13	0.00011	0.0069	16.7	7.6	1	23	1842	1864	1842	1865	0.96
12	13	0.00026	0.017	15.5	6.1	1	23	1870	1892	1870	1892	0.98
13	13	0.029	1.9	9.0	8.2	1	23	1898	1920	1898	1921	0.95

Sequence Information

Coding Sequence: atggtgGACAACAGCGTGCAGTGTCCCGTGTGCACTTTGTACCTGCATGCGGGCATGAATCTCTCGGATCATTTGGAGACACATCCCAAGGAGCAGGTGATCAAGGCATTAGTGCAAATGACAATCGTTGGCAACAGCCCCATGGGCAGCACtctggcagcggcagctgcactCGCCACTGCCGGCAgtggtggcagcagcagcagcaacaccagtcAGCAGCAGACAGCGGTGGCATCGTCAGACGGTTCCGCCTCCTCGGCAGCGCTCGATGCTGATGTGAAACCAGCTGTGGCACcaatagcagcaacaccagTGCCACCAACAGCTGTAGTGGCAGTAGCACCAACAACAGTAGCACCTGCAATGCAATctgtagcaacagcagcaacagcattaaaATCAACAGCACCGAAAGCTGCGTCATTgttggcaaatgcaattgccagcaccagcagcagcagcagtagcagcaacagctcctctagcagcaacagtaacaataacaaattgagCAATCCACCGATAAAGGCAGTCAAAAGCGCGCCACCCTCGACTGAGGCGTCAGCCACCACATCTAGCAACACACCCACCATAAACAACGTGGCCGCCGCCTATCCGCCATCGTTGACTTCTGACTATCGCTACgatcagcaacatcagcagcagcaaccacaacaacagcaggcccaacagcagcagcatcaacaggcGACGCCAACAGCAACGCTTCATGGGTTTCCACGTGGTGCAACCACAATGTTGGTGATACCACAGGCTGCagcacagcatcagcatcactTCCTGGCCACGCAGCCCGCACATTTTgcccatcaacagcagcaacagcagcagtcaccTATGAAGTACACGTATGCAACCACGACGCTGCCACCACCCCCACCACCGCTACAGCTTTTCGCACAGCAGCCGACGACGTCACAGTCGCATCAGAAGCCACCGCCCGCTTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCACAAccaaaacaagcaacaacaacaacaacaccagcagcagcatcaacagcaaccgcagcagcagcaacaacaacatataaGCGTACAACATAATGTAAACCTTGCACCACCGAGTGGGAAGCACAGCAAAGCCCACACGGAGATCTTTCTGAATCctccgccaccaccaccgccacagTCCGCAACGATGCCGTCTTCATCGTCGAATTCCTGCGCCTCCTCCAGACTGCAGCATCCACAACAGCACCAACATCAACACCAGCAATCCCTTCAAATTGGGAACAGCAGTATTGTTGCTATCAACTGCTCCAGCGTTGCGTCGAACCTAATGCCAACATCATCGAGTGGACGAGCCAGCAGTCGCCAATCGACCAATTCGCCATTTGGTGCACTGCTTAATGCAGCAGCGCAAGCTGCCAGCTCATCGCCCGCCTCTTCCAGCGCTTCGGTGTTGCGTTACGCTGAGTCGCCGGTTGCTCACTATTTGGAGCGAGAGAATGGTGACTTTATTGTGCAGGAGACGCCCAAGCACATTGTCGAATGCGTCGAGAAAGATGACGGCGAGTTTTCAGTGATTGAGAGGATCTATCAGTCGCCACCCAGCGTCTTGCACAtacacgatgatgatgaagaagagGAGGATCAGAGCTGGGCAAACAGCGAGGATGAAGATGTCAAGGTGGCACATAATCATGTCGAGGATGGCGACGATGAACGAGAGGACAGTCGCAGCCGAGTTGGTGGCATTAAAACGACAACGAGAAAGTCACGCAAAACAAAATCCGGCAATAGAAACCACAAACGTGCGTCTAAACATCAGTTGGCTGccgaagaggaggaagagttCATGAGTGTGGGCAGCAGTGAGAACGAGgagctggaggaggaggatcagcagcatcaccatcaccaccatcatcaGCAATCGCcatcttcagctgctgctcaggTGGCGTTATCTTCACCGCCACAGCTTTGCACGGCACCATCGACGAGCAGCGGAACCTCTTCAGGGTCCTCCGGCATTGTCAATTCTACATCCAGCGGCACCGTAAAGTCCAAGAAGAATCGTGTTACTGTGCTAAGCGATGTGCCGCTCAATATGAACGAATATTTGGATCTAGTAGGCAACATTGTGGCTTCAAGTCGCATTGGTGCCTCGCGTCCATTTGTCGCTGTTGCGCCCCTCCCGCTGGTCAAGGTGGAAAAGGAGGAGCCGCTGGATGAATACGACAGTGTGCCGAGTGAGATGCAATCGATGGAACAGAAGCCCAGCTTGGAGAATGCCGctggcagcagtagcagcagcaacagcagtagcaacaatgGACACGGCACCACCAGCGTCATACGCATGGCGAGCACaagcaccagcagcagtagtagcAATGTTCCGGCCGATGATCTCACACAGCCGCCGCCAATGAAGGTCGAGGTGGAGCCAACGATGCTGTTGCCGCAACGTTTCTCGGCACCGGCACAGCAGCGTGGTCCCAAAAAGTTAGTCATCAAACCAAAGGccacaacaacggcaacggcgaccACAACGttggcggcagcagcgacggctacggcgacagcgacgaaAAAGACTGATAATAACAacgctgccagcagcagcagcagaagtagcAACTGTGTCGAATCTCTCAGCATATCAAAAACATCGGCAGAATTGGTACAGATCAAGAGTGAGACTTTGGAACAACCATCCACATCGAGTGGTGGTGGCAGCATCTTAGAGAAGCATCTGACTACCAGCTACAGTGGGCAACAATCACGTAAACACTCTGCAGTCAACGATGACGATGCACGCGTCCTTCTCGAGTTTGCCAACTCAAAACAGTTGCCCctggcaagtggcagcaatCCCACCACATTTGTGGTGAATGCAGCAAGCTTTGCGTCCGCCGGATCTGTGTTTGCCAGCAACacgcagcagccacagcagaaGCCCGGTGAAGAGTACATACTGCCTGATGATAACAAAGTGGAAGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCCTCCactcagcaacagcagcagcaacaacatcaacagcatcacCAGCAACCGCATCATCAACATGCAGCTGCGACAGTGCAGGCAACGCATTCGTCATTGCAGCAGACACAGCCGCCAAATTTTAATGACTTCAACTTTTTGTACCaccaaaatgcaacaacaacaacggcagcgacTTCGTCCAGCTTTGTACCCTTTGgtctgcagcaacagcaacatcagcagccacCACATGGCTCAAGTGATGCGACCAATGCAGCAACGCTCGCCTCATCCTCCAGCAACTCATCAGCAATGGATCACGACTCGTCCATGAACGCATCGTTCCGCGTAGCAAAAACACAGTCATCGCTAAATGGCTGGTatcaaccacagcagcaacagcaacaggcgcatcatcatcatcaccagcagcagcagcaacaacaacagcagcagcagccacagccaacaACATCTCAGAATGTGGAGCAGTcaagcaattttattgctgcttTAGCGGCTGTCGATTGTTGCAGTGTGGCGATGGACAGTGATGCAAGCGATGCAAAGTATTTGGATCTGGACACATGCAAGCGGGAACAAttaagcaatagcaacagtcACTTGCCCTCTGCCTCAGCATCCACATCGACAACATCATCCtcatttgcagctgctgccacagaGAGCAGCCTTGTTGGTGGTTTGGGTTTGAATATACGCACGGATGAGAAGATGCCGGCGAAAGGAGAAATTTCCGAGCAGGAGAGCAATTGCGACATTGAGAACTCTTGGAGTCAATCGATGTATGGCGACATATCACAGCGGTACTTTAGAAGCCAATTTGCGGATGGTTACAATCAACAGCTGACCGATTGGCGTCAGCAGGACTATTATCCTGCGCAGGATCTCAgtggccagcagcaacagcgggaGCACAAAAGatttgattttaatgcCGTGGCTTCCGAGTATGTGCAGCCGGATGAGCTGGACGCTTCCTCGAGCTCGGCACGCAGCAATCAATTGCTAGATGCACAGCCCACTACCTCGACGTCGTCATCGGCTTTGCTGGCTGGTCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAGGCAGAGGCAGTTGCAGCCGCCCTGCAGCGGAAGGGTCAACGTCGCAAGATCTACAGGTGTCCACACTGTGTGGCCATCTTCGAGAAGCTCAAGGAGCGCAACGCTCATATGATTGGAGAGCACAACTATGTACGGCAGAACCGTCGACTCATCTGCACCCAGGCCATGGTTAATGGTGCTATGCTGGCACAGCCCCAGGCTGAACACCAAGAGCaagcccagcagcagcagcagcaactgttgatGCAGCCAGGTGGCAGCAATAGCGATGCTCTTCATGAAGATTCCAAGGATGGTATTGTAAAGATCAAGCAGGAGCACTGCCAGGACAAACCAGATTCAACTGACCAGCAGATGCTCGAGCAATTGGAGATGCCAGATGTTAAAGATGCTGGTCTATTAGGTGTTAATGGTGAGAGCGCTCGCGATGCGGACGTAAAGCCTTCCACGACCGTAACGGATCTGAAGCCGACCATGCCACCGCTGAGTATGACAACACCAGCTGCCAAATTGGCAGCTATTTATCGCATGCTCATTTCCTACAATGAGTCGAAGCTTGGTCAGGACCATCATAACCTCAGCGAGCTGGAGCAAAAGGCCATGGAGAAATCCATATTTCTATGCTACGTGTGCCGCACCGATTTCCCCTCGGTGAAGCTGTACGATGCCCACTTAACTGAGCATCCCGCCGAATGCTTTACGTGTGGGAAAAAATTCTATCGTTGGAAGAATTTCTCATTGCATCTGAAGCGTCATCTTGGCTGGAAGGAATTCGGTTGCTATGTCTGCGATAAGAAATTTGTGGTGCGCAGTGCTCTTGTGGAGCATATGCGCATGCATACTGGCCAAACTCCCTTGAAGTGCAAAATATGCGGCAAAAAGTTCAAACGTTATTCCAACTTGACTCAACATCGAAAGCGTCATACCAAAATGACAGTACGGAAAAAGGAATATGTGTGTCATTGTGGTGAGGTCTTGCCATCAAAGGCACGCTTCTTGTGGCATAAAGAAACGCACGACTTGAAACCAAAATGCTGTCCTTATTGCTGTGATCGTTTTGTGCACGCCAATTCGTTGCGTCGTCACATTCGTCTGGCCCATTCGGACAAATTTGATTATGCTGAGCCCATGGAATGCCCCAtgtgcaaacaaatatttgcgaaaACGTCCATTAAGGCACACATGGCAACGCACTCAACGGATCCACAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACACTCGTGGGTGCACGCCAATCGCACTGCCAAACCGTTCAAGTGCGAGCACTGTCCCAAGGCCTTTGTACGCGAACTGGACTTTAAGAATCACATGAATGCGCACAAACAGATCAAGCCCTACACATGTGAGTATTGTGGTTGTAAGTTCATAcgaaaatacaattatatgAGGCATCGGCGAGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAGACTTTCCATCGGCACTACTATTTGATAGAGCATCGACGAATTCACACGGGAGAGCGGCCTTTCCATTGCACCATCTGCGGTAAAAGCTCCACCACGAAGACCAATCACAATAAGCATCTGAAGATACATCATTCGCGAGATCCCTTTACCGTGGAGGTCTAA
Protein Sequence: MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNSPMGSTLAAAAALATAGSGGSSSSNTSQQQTAVASSDGSASSAALDADVKPAVAPIAATPVPPTAVVAVAPTTVAPAMQSVATAATALKSTAPKAASLLANAIASTSSSSSSSNSSSSSNSNNNKLSNPPIKAVKSAPPSTEASATTSSNTPTINNVAAAYPPSLTSDYRYDQQHQQQQPQQQQAQQQQHQQATPTATLHGFPRGATTMLVIPQAAAQHQHHFLATQPAHFAHQQQQQQQSPMKYTYATTTLPPPPPPLQLFAQQPTTSQSHQKPPPAYGAAISQIRSQHNQNKQQQQQHQQQHQQQPQQQQQQHISVQHNVNLAPPSGKHSKAHTEIFLNPPPPPPPQSATMPSSSSNSCASSRLQHPQQHQHQHQQSLQIGNSSIVAINCSSVASNLMPTSSSGRASSRQSTNSPFGALLNAAAQAASSSPASSSASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEDQSWANSEDEDVKVAHNHVEDGDDEREDSRSRVGGIKTTTRKSRKTKSGNRNHKRASKHQLAAEEEEEFMSVGSSENEELEEEDQQHHHHHHHQQSPSSAAAQVALSSPPQLCTAPSTSSGTSSGSSGIVNSTSSGTVKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGASRPFVAVAPLPLVKVEKEEPLDEYDSVPSEMQSMEQKPSLENAAGSSSSSNSSSNNGHGTTSVIRMASTSTSSSSSNVPADDLTQPPPMKVEVEPTMLLPQRFSAPAQQRGPKKLVIKPKATTTATATTTLAAAATATATATKKTDNNNAASSSSRSSNCVESLSISKTSAELVQIKSETLEQPSTSSGGGSILEKHLTTSYSGQQSRKHSAVNDDDARVLLEFANSKQLPLASGSNPTTFVVNAASFASAGSVFASNTQQPQQKPGEEYILPDDNKVEVDEIVISSSSSFASSTQQQQQQQHQQHHQQPHHQHAAATVQATHSSLQQTQPPNFNDFNFLYHQNATTTTAATSSSFVPFGLQQQQHQQPPHGSSDATNAATLASSSSNSSAMDHDSSMNASFRVAKTQSSLNGWYQPQQQQQQAHHHHHQQQQQQQQQQQPQPTTSQNVEQSSNFIAALAAVDCCSVAMDSDASDAKYLDLDTCKREQLSNSNSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRSQFADGYNQQLTDWRQQDYYPAQDLSGQQQQREHKRFDFNAVASEYVQPDELDASSSSARSNQLLDAQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALQRKGQRRKIYRCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQAMVNGAMLAQPQAEHQEQAQQQQQQLLMQPGGSNSDALHEDSKDGIVKIKQEHCQDKPDSTDQQMLEQLEMPDVKDAGLLGVNGESARDADVKPSTTVTDLKPTMPPLSMTTPAAKLAAIYRMLISYNESKLGQDHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEHCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKTFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00537699;
90% Identity: iTF_00553917; iTF_00472574;
80% Identity: -