Drel012964.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila rellima
Gene Symbol
-
Assembly
GCA_035043635.1
Location
JAWNMV010000811.1:7562572-7568544[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.049 3.4 8.4 0.2 1 23 1304 1327 1304 1327 0.94
2 13 7.9 5.5e+02 1.4 0.2 1 23 1492 1514 1492 1514 0.91
3 13 0.00018 0.012 16.0 2.7 2 23 1517 1538 1517 1538 0.97
4 13 6.8e-05 0.0047 17.3 0.2 3 23 1546 1566 1544 1566 0.98
5 13 5.6e-07 3.9e-05 23.9 4.1 2 23 1573 1594 1572 1594 0.97
6 13 5 3.5e+02 2.0 0.4 5 23 1607 1625 1604 1625 0.95
7 13 1.3 92 3.8 5.4 3 23 1632 1653 1630 1653 0.93
8 13 0.14 9.8 6.9 0.2 2 23 1664 1684 1663 1684 0.96
9 13 5.4e-05 0.0038 17.7 0.4 1 19 1690 1708 1690 1712 0.95
10 13 1.5e-05 0.0011 19.4 0.5 1 23 1720 1742 1720 1742 0.98
11 13 0.0001 0.0071 16.8 7.6 1 23 1748 1770 1748 1771 0.96
12 13 0.0002 0.014 15.9 5.9 1 23 1776 1798 1776 1798 0.98
13 13 0.028 1.9 9.1 8.2 1 23 1804 1826 1804 1827 0.95

Sequence Information

Coding Sequence
ATGGTTGATAGTGTGCAGTGTCCCGTGTGCACTTTGTACCTGCACGCGGGGATGAATCTCTCTGACCATTTGGAGACACATCCTAAGGAGCAAGTCATCAAAGCCCTGGTGCAAATGACAATTGTCGGCAATAATGCAATGGGCGGCGCCCTGGCGGCAGCTGCACTCTCCACTGGCGGCAGCGGTTCATCATCAGATGGCGCCTCCTCCTTATCACCGCCAGATGCTGATGTGAAACCAGCTGTGGCAGCACCAGTAGGTGTAGCTgaagcagcaacggcagcagcagcaccagtcccagcaccaccaccaccaataacaacaacagcaacagcaacaacaacattaaaatcaaCAGCACCCAAAGCTGCATCATTGCTGTTAAACGCAAGCatcaacaacaccagcagcagcaacagcagaactTGCAgtatcagcaacagcaacagtaacagtaacagtaatagcaacagcaacaataacaaattgagCAATCCACCGATTAAGGCAGTTAAAAGCGCGCCACCCTCGACTGAGGCGTCAGCCACCACATCCACCACACCCACCATAAGCAGCGTGGCCGCTGCCTATCCGCCATCGCTGACATCCGACTATCGCTAcgatcagcagcaacagcagcagcagcaacaacaggcgaCGCCAACGGCAACGCTTCATGGCTTTCCACGCGGAGCTACCACAATGCTGGTAATACCACATacaccacagcagcagcatcagcagcagcatcatttCCTGGCCACTCAACAGCCTGGTCATTTTGcccatcagcaacagcaacaacagtcggCTATGAAGTACACGTATGCAACATCGTTGCctccgccaccgccgcctcTGCAGCTGTTTGCACAGCAGCCAACAACGTCGCAGTCGCATCAGAAGCCACCGCCCGCCTATGGTGCCGCCATCAGTCAAATTCGATCTCAGCACAACCAAAACAAGCATCATCAACCACAAGAGCATGTAACCGTACAACATAATGTTAACCTAGCACCACCGAGTGGGAAGCACAGCAAAGCACATACGGAGATCTTTCTGAatccaccgccaccaccaccgccacagACCGCGATACCGTCTTCGTCGACCTCCCCGTccgccgcctcctcctcctcaagactgcaacatccacaacaaaaccaacaatcCCTTGCAGCCGGCAGTAGCTATGCAGGAGCCAACTGCTCCAGTCTGATGTCAGCGACAAATGGACGAGGCAGCAGTCGCCAGTCGACCAATTCGCCATTTGGTGCACTGCTTAATGCGGCGGCGCAAGCTGCCAGCTCCTCGTCCACCTCCTCCAGCGCATCTGTGCTGCGTTACGCCGAATCACCGGTTGCCCACTATTTGGAGCGGGACAATGGAGACTTTATTGTCCAAGAGACGCCCAAACATATTGTCGAATGCGTCGAGAAAGATGATGGCGAATTCTCAGTGATTGAGCGTATCTATCAGTCGCCACCCAGCGTGTTGCACATACACGACGATGACGAAGAAGAGGAGGATCATAGcTGGGCAAACAGCGATGATGAGGATCACGCCAAGACACATAACCATGTGGAGGATGGCGATGATGAGCGTGAGGACAGCCGCAGCAGAGTTGGCCTAAAGACAACAACGAAAAAGTCGCGTAAAACAAAATCGAGTGGGAGAATGCACAAACGTGCGTCGTCTAAGCATCGGATGGTTACCACGGAGGATGAGGAAGAGTTCATGAGTGTGGGCAGCAGTGAAAACGAGGAACAGGCAGAGGAGCAACCACACTTGTCCGGTGGGGCAGGTGCACAGGTGACACCGCCGTCTTCGCCGCAACTTTGCACGGCGCCTTCAACGAGCAGTGGAGCGGCTGCAGCAGTTTCTGGCAATGTCAATTCCATGTCCAGCGGTTCCATTAAGTCCAAAAAGAATCGTGTTACAGTCCTGAGTGATGTGCCGCTAAATATGAATGAGTATCTGGATCTAGTCGGCAATATTGTGGCTTCAAGTCGCATTGGTGCGGCTCGACCATTTGCTGCGGTGGCGCCCATTCCGTTGGTCAAGGTGGAAAAGGAGGAACCACTGGACGAATATGACAGCGTGCAAAGCGAGATTCAATCCATGGAGCAAAAGCCAAGCCTAGAACATGCCAGTGGCGGCAGCAGtagtaacagcagcagcaatggacACGGCACCACCAGCGTCATACGCATGGCCAGCACAAGCAGCAACACCACTGTTCCGTCTGAGGATCTCACACAGCCGCCAGCTATGAAAGTCGAGGTGGAGCCAACAGTACTGTTGCCACAACGCTTCTCAGCGCCGGCGCAGCAGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGCCACagcaacggcgacggcgactgcaacgacgacgacgaaaaAGACTGATAACAATGCTGCCAGCAgtagaaacaacaactgctcCGAATCTCTCAGCATATCAAAAGCGTCTGCAGATTTGGTGCAGATCAAGAGCGAAAATGTAGAACCATCCACCTCGAGTGGCAGCATCCTAGAGAAGCATCTAACCACCAACTATACTGGGCAACAAGCGCGCAAGCATTCAACAGTCAATGACGACGATGCCCGTGTCTTGTTGGAATTTGCCAACTCGAAGCAATTGCCGACAGCAGGCAGTAGCAATCCCACGACATTTGTTGTGAATGCGGCCAGTTTCGCATCGGCGGGATCTGTGTTCGCCAACAGCTTGCAGAATCAGCCAACCAAGCCGGGTGAAGAGTACATTCTGCCTGATGATAGCAAAGTGGAAATAGATGAAATTGTGATATCCTCCTCGTCTTCCTTTGCCTCCTCCACGCAGcaagcgcagcagcagccgcatcaGCATCCACCGGCAACTGCTCCAGCTGTTCAACCCACTTTGCAGCATGTACAGCCGCCTACCTTTAATGACTTTAACTTTCTATACCACcaaaatacaacaacgacaacgactgCTTCCAATTTTGCACCATTCGGtcttcagcaacagcagcagcaacaacaacaacatcacggCTCAAGTGAAGCCACGAATGCAGCGACGCTTGCCTCGTCCTGCAGTAACTCGTCAGCTTTGGATCACGAATCCTCCATAAATGCAACGTTCCGTGTGGCCAAGACACAGTCATCTCCGAGTGCATGGTatcagccacaacagcagcagcaacagcagccacaagcGAACACCACTCCGAATGTGGAACAGTCGAGCAATTTTATTGCAGCCTTGGCAGCCGTCGAATGCTGCAGTGCGGCGATGGACAGTGACGCGAGTGATGCCAAGTACTTGGATCTGGATGCATGTAAGCGGGAGCAGTTgagcaatagcagcagccaCTTGCCATCTGCCTCAGCATCGACGTCCACAACATCGTCTTCGTTTGCTGCTGCGGCCACAGAGAGCAGTCTCGTTGGTGGTCTGGGACTAAACATTCGCACTGATGAAAAGATGCCTGCGAAGGGTGAAATTTCCGAGCAGGAGAGCAACTGCGACATTGAGAACTCCTGGAGTCAGTCGATGTATGGGGACATATCACAGCGGTACTTTAGAAACCAATTCGCGGATGGCTACAATCACCAGTTGACCGATTGGCGCCAGGACTATTATCCTGCGCAGGATCTTAGTGGTCAGCATGAGCACCGCGAGCACAAACGATTTGATTTCAACGCGGTAGCCTCTGATTACGCGCAGCCGGGTGAGCTGGACGCCTCCTCGAGCTCTGCCAGAAGCAATCAATTGCTGGATGTGCAGCCTACCACGTCCACGTCGTCATTGGCTTTGCTGGCTGGCCCACCAATAGCCTCGACATCCAGAGCTGCCGCCGAAGCGGAGGCTGTCGCTGCCGCATTGCAACGAAAGCCCGCGCGTCGCAAGATCTACAAGTGTCCACATTGCGTGGCCATTTTCGAAAAGCTAAAGGAGCGCAATGCACATATGATTGGAGAGCACAACTATGTGCGCCAGAATCGGCGACTCATCTGTACGCAGGCGTTGGTTGATGCCGCCATGCTATCACAGCCGCAGgttcaacaacaactacaacaacaacagcagcagcaggagcaattgttgctgcaggCAGGTGGAAGCATTAGCGAAGCCTTGCACGAAGATTCCAAGGATGGCATTGTCAAGATCAAGCAGGAGCACTGTCACGACAAGCCCGATTCATCCGAGCAGTTGCTTGATCATTTAGATCTGCCGGATGTGAAAGATGCAGGCTTATTAGACGTTAACGTAGAGAATGGACGTGATGCAGACGTGAAACCCGCTACCAACGCAACTGATGTGAAGCCGACTATCGCGCCTTTGGCTATGACAACACCTGCTGCCAAATTGGCGGCGATTTATCGCATGCTTATTGCCTATAATGAGTCGAAGCTCGGACAGGATCATCACAACCTCAGCGAGCTGGAGCAAAAGGCCATGGAGAAATCCATATTTCTGTGCTACGTCTGTCGCACCGATTTCCCCTCTGTCAAACTGTACGATGCACATCTGACTGAACATCCCGCCGAGTGCTTCACCTGTGGCAAGAAATTTTATCGCTGGAAAAACTTTTCACTGCATCTGAAACGTCATCTTGGCTGGAAGGAATTCGGTTGCTATGTCTGCGATAAGAAATTCGTTGTGCGCAGTGCCCTTGTCGAGCATATGCGAATGCACACTGGCCAAACTCCGTTGAAGTGCAAGATATGCGGCAAAAAGTTCAAGCGTTATTCCAACTTGACTCAGCATCGGAAGCGCCACACCAAAATGACGGTGCGAAAGAAGGAATATGTGTGTCACTGCGGCGAGGTGTTGCCCTCCAAGGCGCGATTCCTGTGGCATAAGGAAACGCACGATTTGAAGCCCAAGTGCTGTCCATATTGTTGCGATCGTTTTGTCCACGCCAATTCACTGCGCCGACACATCCGACTGGCGCATTCGGACAAGTTTGATTATGCTGAGCCCATGGAATGTCCCATGTGCAAGCAGATCTTTGCCAAAACGTCCATCAAGGCACACATGGCCACTCACTCGACGGATCCGCAATACGATTGCGCCATCTGCAACAAGAGCTTCTCCACAAAATGGAATCTCAAGATACATTCATGGGTGCATGCAAATCGCACAGCCAAACCGTTCAAGTGCGAGTATTGCCCCAAGGCCTTTGTACGCGAGCTGGACTTCAAGAACCACATGAATGCGCACAAACAGATTAAGCCGTATACCTGCGAGTACTGTGGTTGCAAATTCATACGCAAGTACAACTACATGCGACATCGGCGAGAGCATCATGGCAACAAGAAGTTCACCTGCGATCAGTGCGACAAATCTTTTCATCGTCACTATTATCTGATTGAGCATCGGCGAATTCACACTGGGGAACGGCCCTTCCACTGCACCATCTGCGGCAAGAGCTCGACCACGAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGTGATCCCTTCACCGTGGAGGTCTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNNAMGGALAAAALSTGGSGSSSDGASSLSPPDADVKPAVAAPVGVAEAATAAAAPVPAPPPPITTTATATTTLKSTAPKAASLLLNASINNTSSSNSRTCSISNSNSNSNSNSNSNNNKLSNPPIKAVKSAPPSTEASATTSTTPTISSVAAAYPPSLTSDYRYDQQQQQQQQQQATPTATLHGFPRGATTMLVIPHTPQQQHQQQHHFLATQQPGHFAHQQQQQQSAMKYTYATSLPPPPPPLQLFAQQPTTSQSHQKPPPAYGAAISQIRSQHNQNKHHQPQEHVTVQHNVNLAPPSGKHSKAHTEIFLNPPPPPPPQTAIPSSSTSPSAASSSSRLQHPQQNQQSLAAGSSYAGANCSSLMSATNGRGSSRQSTNSPFGALLNAAAQAASSSSTSSSASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEEEEDHSWANSDDEDHAKTHNHVEDGDDEREDSRSRVGLKTTTKKSRKTKSSGRMHKRASSKHRMVTTEDEEEFMSVGSSENEEQAEEQPHLSGGAGAQVTPPSSPQLCTAPSTSSGAAAAVSGNVNSMSSGSIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDEYDSVQSEIQSMEQKPSLEHASGGSSSNSSSNGHGTTSVIRMASTSSNTTVPSEDLTQPPAMKVEVEPTVLLPQRFSAPAQQRGPKKLVIKPKATATATATATTTTKKTDNNAASSRNNNCSESLSISKASADLVQIKSENVEPSTSSGSILEKHLTTNYTGQQARKHSTVNDDDARVLLEFANSKQLPTAGSSNPTTFVVNAASFASAGSVFANSLQNQPTKPGEEYILPDDSKVEIDEIVISSSSSFASSTQQAQQQPHQHPPATAPAVQPTLQHVQPPTFNDFNFLYHQNTTTTTTASNFAPFGLQQQQQQQQQHHGSSEATNAATLASSCSNSSALDHESSINATFRVAKTQSSPSAWYQPQQQQQQQPQANTTPNVEQSSNFIAALAAVECCSAAMDSDASDAKYLDLDACKREQLSNSSSHLPSASASTSTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRNQFADGYNHQLTDWRQDYYPAQDLSGQHEHREHKRFDFNAVASDYAQPGELDASSSSARSNQLLDVQPTTSTSSLALLAGPPIASTSRAAAEAEAVAAALQRKPARRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVDAAMLSQPQVQQQLQQQQQQQEQLLLQAGGSISEALHEDSKDGIVKIKQEHCHDKPDSSEQLLDHLDLPDVKDAGLLDVNVENGRDADVKPATNATDVKPTIAPLAMTTPAAKLAAIYRMLIAYNESKLGQDHHNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMTVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00537699;
90% Identity
-
80% Identity
-