Bbre012566.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus breviceps
Gene Symbol
-
Assembly
GCA_014825925.1
Location
CM026182.1:371140-375492[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.0099 0.73 10.2 0.0 1 20 57 76 57 78 0.95
2 19 0.17 13 6.3 2.3 1 20 95 114 95 116 0.95
3 19 0.00011 0.0084 16.3 3.0 2 23 150 171 149 171 0.94
4 19 0.00016 0.012 15.9 2.2 1 23 175 197 175 197 0.97
5 19 0.00015 0.011 15.9 0.6 3 23 205 225 204 225 0.97
6 19 2.6e-05 0.002 18.3 3.6 2 23 232 253 231 253 0.96
7 19 0.098 7.3 7.1 2.5 1 19 262 284 262 286 0.73
8 19 0.15 11 6.5 0.2 3 23 292 311 291 311 0.95
9 19 0.41 30 5.1 2.3 3 13 319 329 318 332 0.89
10 19 0.038 2.8 8.4 2.4 1 23 419 441 419 441 0.97
11 19 3.6e-06 0.00027 21.0 1.1 3 23 452 473 451 473 0.96
12 19 0.00013 0.0094 16.2 4.9 1 23 479 501 479 501 0.98
13 19 0.031 2.3 8.7 0.4 1 23 505 527 505 527 0.97
14 19 3.9e-06 0.00029 20.9 1.5 3 23 535 555 533 555 0.97
15 19 1.1e-05 0.00084 19.5 0.2 1 23 561 583 561 583 0.98
16 19 0.07 5.2 7.6 0.9 1 23 589 611 589 611 0.97
17 19 3.4e-07 2.5e-05 24.3 0.1 2 23 618 639 617 639 0.97
18 19 5.8e-07 4.3e-05 23.6 0.6 1 23 645 667 645 667 0.97
19 19 1.1e-07 8e-06 25.9 1.9 1 23 673 695 673 695 0.99

Sequence Information

Coding Sequence
ATGATTGAGAAAAAGAAAACAGATTTAGCTTTGAAGATAAAACCGAAAAGCGTGAAGACGATACCAGCCAAACGGAATCAGTCTCGCACCGCTAAATCGTCCAACGAGGAAGCTCGATCGTTTGTGAACAAAGTGATCGATAACTCTCACGTCGTCCAGGAAGCATCGTATCGATGCGAGTCCTGTGACGAGGAGTTCGACACGGAGGCTGCTCTGTTGGTACACAGAACCGAGCAGTCGATCCTTCGAACTCGGGAAGCATTGAAAAAAGCTGAAAAGAAATACACGTGTGACGCGTGCTGCGAAAGTTTCACGAAGAAGGTACAACTGTTCAAGCATCGAGGTCGATGCAAAAAGTCGACGATAGCTGAGAGCAAACAGCATAAAGCGAAGGAcaaaacgataaaaacgaaacgaaaggaaccGAATGTTTCTACTGGTCCGATCGAGTGCAATGTGTGTCATAAAGtttttaagaagaagaaatatctaaATGTTCATAAAACATTGCATGGAGCGCCTCATATTTGTCACGTATGTGGTGCCAAATTGACTTCTGAATATTATTTGAAGATTCACATTAGGAGACACAATAAAGAATTCACTGAATTTTGCGAGGTGTGTAATAAGGGATTTTACTTAAAGGCAACGTTGAAAACGCACATGAGTGTGCATAGTAATGATAAACCATGCATTTGTGAGGTTTGTCACAAGTCTTTCGGTAATAGAGTTTATTTGAGAAGTCACATGAAGATTCACAGTCAGCCTGAAAATAGGAGGAAGTACAGATGCGAAATTTGTGGGTTCGAGACTTTCTACAGTTACTGTTATAAGGAACATCTGTGGACGCATACGGGAGAAAGTCAGGTGGCTTGTGAGGTTTGCGGTAAATTGATCAGGAGACAGTATATGAAGATTCATATTAGAATACACACTGGTGAGAAGCCGGAGATCTGTGAATTTTGCGGGAAAGCATTTAGTTCGAGGAAGTGTCAGGAGATCAGCATGGAGGAAGCGAAAATAGAGCAGATAGAAACGCTCGAGGATATGGAACTGGTCAAATACCAGAATGACGTTTGCACGGTCGAAGAGTTCGAACAGATCAGTCATCAAGAGATAGTAACGGACACGTTAGAAGAAAGTAACGACACGGAGATGAAACTGATtctagaagaagaaaaagaagaagaagaaacaggaAACGTTAACATagattataacaataaatacgAGAGCAGAAAATGCTCGGTCATTTATGAATGCGACGTCTGTAACAAAAAAATGCGTAAAAAGCTTCAATTTCTAAAACATAGGCAGGACCATGAAAGGAATTACGAAGAAACTGGTGGTCATTGCGAGGAATGTGATAAAAGTTTCGCGGATGaagagaaattgaagaaacacATGATCAAAGTGCACCAAAAGGAGAAACCTTTTCAATGTGTTCTCTGTAATAAATGCTTCAAAACGGAAGAATTCTTAAAGACACACCTGAAGCAACACAACAAACGTTTCACGTGCGATATCTGCGGTATCTCGAAGGTGTCTGGCTATGATCTTCgtttacataaaaagaaacataacgAGGAATATGTGACGCACTGTGAAATCTGCGGCAAAGGCTTCTACACGAATCAAACCCTGGAAAGACACTTACTCACACATACCGGGGAGAAACCATTTGTTTGCAAGGTATGCAACACCCCTTACGCGAGTGCTGCGTATCTGAATACGCACATGAAGTCTCACGGCGAACGAGAGAAACACAAGtgcaatatttgtaatttcgaaAGTTACTGGAAGGCGGCTCTAAAGGTGCACCTTAAGATACACACTGGAGAGAACCTGATCACCTGTGAGATATGCGGGAAATCAGTCTCGAGTAAAGCTTATCTGCAGATCCATATGCGTATACATTCTGGCGAGAAACCACACATTTGCGAAATATGTGGCAAGGCCTTCAGCGTTCGAAAATATCTGATTGTACATTTGAGAACGCATACAGGTGAAAGACCGTATGAATGTAAGGTATGTCAGAAAAGGTTCACGCAGCAGGGTTCACTGAATTCACATATGAAGTCGCATAACGAAAGGAAGTGA
Protein Sequence
MIEKKKTDLALKIKPKSVKTIPAKRNQSRTAKSSNEEARSFVNKVIDNSHVVQEASYRCESCDEEFDTEAALLVHRTEQSILRTREALKKAEKKYTCDACCESFTKKVQLFKHRGRCKKSTIAESKQHKAKDKTIKTKRKEPNVSTGPIECNVCHKVFKKKKYLNVHKTLHGAPHICHVCGAKLTSEYYLKIHIRRHNKEFTEFCEVCNKGFYLKATLKTHMSVHSNDKPCICEVCHKSFGNRVYLRSHMKIHSQPENRRKYRCEICGFETFYSYCYKEHLWTHTGESQVACEVCGKLIRRQYMKIHIRIHTGEKPEICEFCGKAFSSRKCQEISMEEAKIEQIETLEDMELVKYQNDVCTVEEFEQISHQEIVTDTLEESNDTEMKLILEEEKEEEETGNVNIDYNNKYESRKCSVIYECDVCNKKMRKKLQFLKHRQDHERNYEETGGHCEECDKSFADEEKLKKHMIKVHQKEKPFQCVLCNKCFKTEEFLKTHLKQHNKRFTCDICGISKVSGYDLRLHKKKHNEEYVTHCEICGKGFYTNQTLERHLLTHTGEKPFVCKVCNTPYASAAYLNTHMKSHGEREKHKCNICNFESYWKAALKVHLKIHTGENLITCEICGKSVSSKAYLQIHMRIHSGEKPHICEICGKAFSVRKYLIVHLRTHTGERPYECKVCQKRFTQQGSLNSHMKSHNERK