Spal013151.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Scaptomyza pallida
Gene Symbol
su(Hw)
Assembly
GCA_018152965.1
Location
JAECXP010000260.1:333984-337060[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00062 0.046 14.2 2.2 1 20 232 251 232 253 0.94
2 12 2.6e-06 0.00019 21.7 0.4 3 23 304 325 302 325 0.93
3 12 0.0088 0.65 10.6 0.1 1 23 331 353 331 353 0.97
4 12 7e-07 5.2e-05 23.5 2.5 1 21 360 380 360 381 0.95
5 12 6.9e-06 0.00051 20.4 0.8 2 23 393 414 392 414 0.96
6 12 7.5e-05 0.0055 17.1 5.5 1 23 425 447 425 447 0.99
7 12 5.6e-05 0.0041 17.5 0.8 1 23 453 475 453 475 0.97
8 12 1.5e-05 0.0011 19.3 0.8 1 23 481 503 481 503 0.99
9 12 1.5e-06 0.00011 22.5 2.5 1 23 509 531 509 531 0.98
10 12 3.2e-05 0.0023 18.3 0.4 1 23 535 557 535 557 0.96
11 12 3.8e-05 0.0028 18.1 0.1 1 20 565 584 565 589 0.92
12 12 2.1e-05 0.0015 18.9 0.3 3 23 608 629 606 629 0.97

Sequence Information

Coding Sequence
ATGAGCGCTAAAAAGGACGCCACGGAGCCAAACACCCCTGGGTCCAGCAGTAATCATCGAGGCACAATGATCAAAGTCGTTGAGATTGAGAAAATTTCAACACCCAAGGACAAACGCACTGGTACACGCATGAAGCTGCTCAACGATGTGACTGCTGCCAAGGCAAAAACATCGCCTCGCGTTAAACAGGAGAAACGCACAAGCATCAAAATACTCAACAACGATGAATCAGCGATCAGTCCAAAAGGTGGCAGTGAGAGGCGCTCTGCTGGCAAATCCGCAACTGTTACTAAATCAGCATCTGTGAGTCCAGTGAAAATATTGAATGAGAAGCGTATTTCGACCCCCTCTACGCCTGTGGAGTCAGCTAAGATTAGGACATCGCCTGGCAAGAAAAAGAAAATGGATCACTATGTGCTGCAGGCAATCAAAAGTGAAAACAACAAATCGGAAAGCACAACAAACATCACAGTGGAACTCGATGATGACGGGGATACCATTGATTTTATACTCGCGGACGAAGACGCCGAATTGGGTGCTGCAAAGGAGAATGACGACGAGTTTGTTGTGTCTGCCGTGGAGGATGATGATGATGATGACGATCAGACTGATGACGAGGGCACTGCTGTCGGTGAAGGGAGTGGCAAGAACCGCAATGCCGCCAATAACACCGAACTCAAGGAAATGGTAGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGGCGTGTCAAAAGCCTTAAGAAACACTTGGAATTTTGTCGCTATGACAGTGGCTATCATTTACGTAAAGCGGACATGCTCAAAAATCTGGAGAAGATCGAAAAGGATGCAGTGGTCATGGAGAAGAAAGACATATGTTTCTGCTGCAGCGAAAGCTACGACACCTTTCATCTGGGCCACATCAATTGCCCCGACTGCCCCAAGTCTTTTAAGACACAGACAAGCTATGAGCGCCATATCTTCATTACTCACTCGGAGTTCAATGATTATCCCTGCTCCATTTGCAATGCAAAATTGCGTAGCGCTGCTTTACTGAAACTGCACGAGCAGCAGCATCAATTGCGTGGCAAGCCCTTTGCCTGCAAGATCTGTGGCAAGGATTTTACGCGCTCTTACCACCTGAAGCGCCACCAGAAGTATTCGTCTTGCTCGGCTAACGAGAATGATACCATGAGCTGCAAGGTGTGCGATCGTGTCTTCTTTCGCCTGGACAATCTGCGTGCCCATCTCAAGCAGCATTTGGGCACCCAGATTGTTAAGAAGCCCGAATACATGTGTCATGAGTGCAAGAATTGCTTTTACAGCCTATCAACGCTTAACATACATATACGCACCCACACTGGAGAGAAACCCTATGATTGCGATCTGTGCGACAAGAAGTTTTCGGCACTGGTGGCACTCAAAAAGCATCGTCGCTATCACACCGGCGAGAAGCCCTACACATGTACAGTGTGTAGCCAATCTTTTGCTGTTAAGGAGGTGCTCAATCGCCATATGAAACGGCATACGGGCGAACGCCCCCACAAGTGCGACGAATGTGGCAAGAGTTTCATTCAGGCCACACAGCTGCGTACGCATTCCAAGACGCACTTGCGTCCCTACGCCTGCACCGAATGTCCCGAAAAGTTCAAGACAGAGAAACAACTCGAGCGCCATGGTAAGGAACATTCTCGTCCCAAACGTCGCTCTTTTCCCTGTACGGATTGCTCACGTAGTTTCCGTTCCAGTGCATTGCTTAAAGAGCACATTGATGCTGGCGATCATTCGCCTAAAGCAGCACGGGCCAAGCGTACGGCAAAGCCGATCGAGCGAACCGATTGTGCAATATGCGACAAAAATTTCGATAGCACTGAAACGCTCAGGAACCACATACGCACCGTGCACGAGTGTGATCCGGATGATATCTTTGGCACTGAGCCACCACCAGCAAAACGCAGGGCCAGAAAGAGCGTGCGCGCCTTGGAGCCAAGCGAAGGGGAAGATGATGAAAATGTGGCTGATGCAACGGCTGCTGCCAACACATCGGCAGGCTCGCTCATCTCCAGTAAAACGGATGGCAATGGGGTTGTGGTGCGCGAGTTTCTGGTGGACGAAGGCGACGGCAACACGCAGACAATTGTGCTCGAAAACGAAGTGTACACGATTTTGCCATTGGATGGTGGTGCTAGTGCAACTGAAGCTTCTTCCAACCAAGATAATGTTAAAGCCGAGTCGAAGAATAAGGAAAAGCAAAAGCAATCCGTTTCACCCGTTGTCAAAAAGGAACAACGCAAATCGCTGGCCGCAAGCTTGGCAGCTGCCATTGCTGATAATCAGGATGAGCCGGTCAGCGATGATGATTTCAGTGGCGAGGTACTCACCGAAGATGATCTGAAGTTGAAGGAGAACATAGCCAAGCTAATTGACATGCTGGTGGATCCAGACACACTAAAGAAATACGGCTGGCCCAACAGCCCCGAGGAGACGGTCCTGTGCAAGGTCATCGAGAACTGTGGCTACGATCTGAACAAGGGTGGCGAAAACTATTCCGAATTGGATTATGGCAGCCGTATGCGCGAGTATTGTAAGCTTCTGTTCACGGTGGTTGTGCACAATGATTCCATCAAATCGCTGCTAAACAATTTCCCCATTGACGATGTCATTGAGTACGTTTTGGGAGATGAGGATCAAGACGGAGATCAAGACATGGAAAAGGATAAGGAAAAGGATAAAGACAAGGAGATAGAAAATGTGAAGAAAGATGAAGTTGACGACGAAGACGATTAA
Protein Sequence
MSAKKDATEPNTPGSSSNHRGTMIKVVEIEKISTPKDKRTGTRMKLLNDVTAAKAKTSPRVKQEKRTSIKILNNDESAISPKGGSERRSAGKSATVTKSASVSPVKILNEKRISTPSTPVESAKIRTSPGKKKKMDHYVLQAIKSENNKSESTTNITVELDDDGDTIDFILADEDAELGAAKENDDEFVVSAVEDDDDDDDQTDDEGTAVGEGSGKNRNAANNTELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSAALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFFRLDNLRAHLKQHLGTQIVKKPEYMCHECKNCFYSLSTLNIHIRTHTGEKPYDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCDECGKSFIQATQLRTHSKTHLRPYACTECPEKFKTEKQLERHGKEHSRPKRRSFPCTDCSRSFRSSALLKEHIDAGDHSPKAARAKRTAKPIERTDCAICDKNFDSTETLRNHIRTVHECDPDDIFGTEPPPAKRRARKSVRALEPSEGEDDENVADATAAANTSAGSLISSKTDGNGVVVREFLVDEGDGNTQTIVLENEVYTILPLDGGASATEASSNQDNVKAESKNKEKQKQSVSPVVKKEQRKSLAASLAAAIADNQDEPVSDDDFSGEVLTEDDLKLKENIAKLIDMLVDPDTLKKYGWPNSPEETVLCKVIENCGYDLNKGGENYSELDYGSRMREYCKLLFTVVVHNDSIKSLLNNFPIDDVIEYVLGDEDQDGDQDMEKDKEKDKDKEIENVKKDEVDDEDD