Dgau000655.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila gaucha
Gene Symbol
su(Hw)
Assembly
GCA_035045545.1
Location
JAWNOY010000025.1:336100-340435[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00067 0.047 14.3 2.2 1 20 217 236 217 238 0.94
2 12 2.8e-06 0.0002 21.8 0.4 3 23 289 310 287 310 0.93
3 12 0.006 0.43 11.3 0.2 1 23 316 338 316 338 0.97
4 12 7.5e-07 5.3e-05 23.5 2.5 1 21 345 365 345 366 0.95
5 12 3.2e-06 0.00023 21.5 0.6 2 23 378 399 377 399 0.96
6 12 0.0001 0.0074 16.8 5.3 1 23 410 432 410 432 0.99
7 12 8.1e-05 0.0058 17.1 0.9 1 23 438 460 438 460 0.97
8 12 1.6e-05 0.0012 19.3 0.8 1 23 466 488 466 488 0.99
9 12 1.5e-06 0.00011 22.6 3.0 1 23 494 516 494 516 0.98
10 12 0.0045 0.32 11.7 1.4 1 23 520 542 520 542 0.97
11 12 0.00018 0.013 16.0 0.2 3 22 552 571 550 574 0.90
12 12 2.9e-05 0.0021 18.5 0.3 3 23 594 615 592 615 0.96

Sequence Information

Coding Sequence
ATGAGCGCCAGCAAGGACGCCCCTGCGGCAGCCCCTGCCCCCAGCAACGAGGTCAGCACCCCCGTCATCAGAGTTTTGGACGTGGAGCTGAAGGAAAAACGCACTGGCACGCGGATGAAACTGCTCAACGATGTTGCCGCAAAGACTCCTCGCCCCAAGCACGAGAAACGCACCAGCATCAAGATACTCAACAACGATGAAGCCCAGAGCACATCGAAAGGCGGCGACAAGCGTGCCACGCCCAAAACCGCTAGCCCAGGTGTGAAGATATTAAACGAAAAGCGAATTGCACCCTCGGCCGCAGCTGTCGAAACAGCCAAGATAAAGACGTCGCCcaccaagaagaagaaaatggaTCACTATGTGCTGCAGGCCATCAAAAGTGAAAGCAGCAAAGCGGAAAACACCACCAGCGTGGTGGTGGTTGAGGACGACGACACCATCGATTTTATACTGGCCGACGATGATGTCGAGCTCGGCGATGCTGCCAAAGAGAATGGCGAAGAGTTTGTGGTGTCTGGCGTTGACGAggatgacgacgatgatgatgacgatgacgacgatgatggGGTAGCAGTAGGTGCAAGCGGTGGAaaacgcaacagcagcaacaacaacaacagcagcgagcTCAAGGAAATGGTGGAGCACGTGTGCGGCAAATGCTACAAGACCTTCCGTCGCGTCAAGAGTCTGAAGAAGCACTTGGAGTTCTGTCGCTACGACAGCGGCTATCATCTGCGCAAGGCGGACATGCTTAAAAACCTGGAGAAGATTGAACGCGATGCGGTGGTCATGGAGAAGAAGGACATATGTTTCTGCTGCAGCGAGAGCTACGACACTTTTCATTTGGGACACATCAACTGCCCGGATTGCCCAAAGTCGTTCAAGACGCAGACGAGCTATGAACGCcatattttcatcacacacTCGGAGTTCAACGACTATCCATGCTCCATTTGTAATGCCAAGCTGCGTAGCTCCGCGCTGCTGAAGCTCcacgagcagcagcatcagtcgAGAGGCAAGCCCTTCGCCTGCAAGATCTGCGGCAAGGACTTTACGCGATCGTATCACCTAAAACGCCATCAGAAGTATTCGTCCTGCTCGGCCAATGAGAATGATACCATGAGCTGCAAGGTGTGTGATCGCGTCTTCTATCGCCTGGACAACTTGCGCGCTCATCTCAAACAGCACCTGGGCACCCAGGTGGTCAAGAAGCCAGAGTACATGTGTCATGTCTGCAAGAATTGCTTCTACAGTCTGTCCACACTCAACATTCACATACGCACTCACACGGGCGAGAAGCCCTTCGATTGCGATTTGTGCGACAAGAAGTTTTCGGCTTTGGTGGCCCTCAAGAAACATCGTCGCTATCATACGGGCGAGAAACCCTACACCTGCACAGTGTGCAGTCAATCCTTTGCCGTCAAGGAGGTGCTCAACCGGCACATGAAGCGGCATACAGGTGAGCGTCCGCACAAGTGCAATGAGTGTGGCAAGAGCTTCATACAGGCGACACAGCTACGCACGCATTCCAAGACGCATCTGCGTCCCTACTCCTGCTCCTTGTGCATTCAAAAGTTCAAGACGGAGAAGCAACTCGAGCGCCATGTCAAGGATCATTCGCGTCAGAAGCGTCCGTCCTTTGGCTGCTCGGACTGCTCCCGAAGTTTTCGCACCAGCGCACTGCTCAAGGAGCACATTGACTCGGGCGATCATTCACCTATTAAACCAACTCGTGCCAAGCGCACGGCGAAGGCGATCGAGCGCACGGATTGTGCCATTTGCGACAAGAACTTCGATAGCACTGATACGCTCAAAAATCACATACGCAGCGTGCACGAGTGCGATCCGGATGATATATTCGGCACAGAGCCGCCAGCCAAGCGCAAGGGCAAAAAGACCGTCGTGGTGctagaggaagaggaagaggaggcTAAGGAGCAGAAAGACCAGGAAGAGGAAACGCCAGCTGCCAACACATCATCTGGCTCGCTCATCTCCAGCAAAACGGATGACAATGGGGTCGTCGTCCGAGAGTTTCTCGTGGATGAGGGCGACGGCAATGCACAGACCATTGTTCTCGAGAACGAGGTCTACACCATTTTGCCTTTGGAGGGTGCCGCCAGTGCAACGGAGCCATCGGCAGAGGGCGACGACGTCAAGGCCGAGTCGAAGGAAAAGTCACAGCCGACTGTGTCGCCGGTGGTCAAGAAGGAGCAGCGCAAATCGCTGGCCGCCAGCTTGGCTGCTGCCATTGCGGACAATTTGGATGAGCCGTCAAGCGACGATGAGTTCAGCGGCGAGGTGCTCACTGAGGAGGATATAAAGCTGAAGGAGAACATAGCCAAGCTAATCGACATGCTGGTCGATCCGCAAACACTCAAGAAATACAACTGGCCGAACAGCTCCGAGGAGTCGGTGCTGTGCAAGGTCATCGAGAATTGTGGCCACGATCTGGCCAAGGGCAGCGAAGCCTATGCCGAGTTGGACTACGGCAGTCGCATGCGCGAATATTGTAAACTCCTGTTCACAGTGGTCATTCACAATGATTCCATAAAGTCGCTGCTCAACAATTTTCCCATCGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATCAGGACCAGGAGCTGGACACGGACAAGGgcaaagagaaggagaaagatGATAAATTGGATACGGACACTAGGCAGGATACCGATGAAGCCGAGGCTTAG
Protein Sequence
MSASKDAPAAAPAPSNEVSTPVIRVLDVELKEKRTGTRMKLLNDVAAKTPRPKHEKRTSIKILNNDEAQSTSKGGDKRATPKTASPGVKILNEKRIAPSAAAVETAKIKTSPTKKKKMDHYVLQAIKSESSKAENTTSVVVVEDDDTIDFILADDDVELGDAAKENGEEFVVSGVDEDDDDDDDDDDDDGVAVGASGGKRNSSNNNNSSELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSSALLKLHEQQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCSLCIQKFKTEKQLERHVKDHSRQKRPSFGCSDCSRSFRTSALLKEHIDSGDHSPIKPTRAKRTAKAIERTDCAICDKNFDSTDTLKNHIRSVHECDPDDIFGTEPPAKRKGKKTVVVLEEEEEEAKEQKDQEEETPAANTSSGSLISSKTDDNGVVVREFLVDEGDGNAQTIVLENEVYTILPLEGAASATEPSAEGDDVKAESKEKSQPTVSPVVKKEQRKSLAASLAAAIADNLDEPSSDDEFSGEVLTEEDIKLKENIAKLIDMLVDPQTLKKYNWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQELDTDKGKEKEKDDKLDTDTRQDTDEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01325058;
90% Identity
iTF_00502661;
80% Identity
-