Dkok010049.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila kokeensis
Gene Symbol
su(Hw)
Assembly
GCA_035042145.1
Location
JAWNLT010000346.1:6548662-6552117[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00094 0.061 13.8 1.6 1 20 226 245 226 247 0.94
2 12 2.8e-06 0.00018 21.7 0.4 3 23 298 319 296 319 0.93
3 12 0.1 6.6 7.4 0.1 1 23 325 347 325 347 0.96
4 12 7.6e-07 4.9e-05 23.5 2.5 1 21 354 374 354 375 0.95
5 12 3.3e-06 0.00021 21.5 0.6 2 23 387 408 386 408 0.96
6 12 0.00011 0.0068 16.8 5.3 1 23 419 441 419 441 0.99
7 12 8.2e-05 0.0053 17.1 0.9 1 23 447 469 447 469 0.97
8 12 1.9e-05 0.0012 19.2 0.7 1 23 475 497 475 497 0.99
9 12 2.6e-07 1.7e-05 25.0 2.7 1 23 503 525 503 525 0.98
10 12 6.2e-05 0.004 17.5 1.8 1 23 529 551 529 551 0.97
11 12 0.00013 0.0083 16.5 0.1 1 20 559 578 559 583 0.93
12 12 3.3e-05 0.0021 18.4 0.3 3 23 603 624 601 624 0.96

Sequence Information

Coding Sequence
ATGAGCGCGAGAAAGGACGCCTCCGAGGCGAACTCCCTCAGCTCCAGCAGcgatggcggcggcggcaacgtGGTCAAAATCTTGGACGTTGAGAAACTAACATCAGCCAAGGATAAACGTCCTGGCACCCGCATGAAACTGCTCAACGATGTGACACCGAGTAAGGCAAAAATATCTGCACGCGTCAAGCAAGAGAAACGCACCAGCATCAAAATACTCAACAACGATGATTCAGCGAGCAGTcccaaaggcaaaggcagcaGCGATAGGCGCTCCAGTGGCAAAGCAGCGACTGCACCACCAGTCGTCAAAATCTTAAATGAGAAACGCATTGCGCCGACCTCGACGCCCGTGGAGACGGCAAAGATTAAGACATCACCcggcaaaaagaagaaaatggaTCACTATGTGCTGCAGGCCATCAAGAGTGAGAACAGCAAATCAGACAATACGACGGCCAGCATCGTGGAGATCGAGGATGATGACGATACCATTGATTTTATACTCGCCGATGACGATGTCGAGTTGGGTGTCGCCAAGGAGAATGACGCTGAGTTCATTGTCTCCGGTGTGGAAgaagacgacgatgacgatgatgatgaggatgagggtACCACTGAGGGCACTGGTACAACGAATGCCGGCAATAACAGTGAACTCAAGGAAATTTTGGAGCATGTGTGCGGCAAGTGCTACAAGACATTCCGGCGCGTCAAGAGCCTGATGAAGCACTTAGAATTCTGCCGCTATGACAGTGGGTATCATCTGCGCAAAGCGGACATGCTCGACAATCTGGAGAAGATCGAGAAGGATGCGCTGGTCATGGAGAAGAAGGACATCTGCTTTTGCTGCAGCGAGAGTTACGACACCTTCCACCTGGGCCACATCAATTGCCCCGATTGCCCCAAGTCATTTAAGACACAGACCAGCTATGAGCGTCACATCTTCATCACTCATTCCGAGTGCAATGATTATCCCTGTTCCATATGCAATGCGAAATTGCGCAGCGGCGCCTTACTAAAACTgcacgagcagcagcatcaattgCGTGGCAAACCCTTCGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCGTACCACTTGAAGCGCCACCAGAAGTATTCGTCGTGCTCAGCCAACGAGAATGATACCATGAGCTGCAAGGTCTGCGATCGCGTCTTCTATCGCCTCGACAATCTGCGCGCCCATCTCAAACAGCACCTGGGCACCCAGGTGGTCAAGAAGCCGGAGTACATGTGTCATGTGTGCAAGAATTGCTTCTACAGTCTTTCGACGCTCAACATACATATACGCACCCACACTGGAGAGAAGCCCTTCGATTGCGATCTTTGCGACAAGAAGTTTTCCGCCTTGGTGGCGCTTAAGAAGCATCGACGCTATCACACCGGCGAGAAACCCTACACCTGTTCAGTGTGCAGTCAATCTTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAACGGCACACGGGCGAGCGTCCACACAAGTGCAGTGAGTGCGGCAAGAGCTTCATTCAGGCCACACAGCTCCGCACGCATTTAAAGACGCATCTGCGTCCCTTCCCCTGCTCCAAGTGCACCGAAAAGTTTAAGACAGAGAAACAACTTCAGCGTCACGCTAAGGAGCATTCGCGGCAGAAGCGTCGCTCCTTTCCCTGCACGATATGCCGCCGAAGCTTCCGCACTAGCGCGCTGTTGCAGGAGCATGTTGATGCTGGCGATCACCCACTTGATAAGCAGGTGAAGGTTAAGCGCTCGGCCAAGACGATTGAGCGCACCGATTGCGCCATTTGCGACAAGAACTTCGACAGCACCGATACGCTGAGGAATCACATTCGCAGCGTGCACGAGTGCGATCCGGATGACATTTTTGGCACGGGGCCACCGCGCGCAAAGCGACGAAAGAAGACCGTCCAATTTGTGGCACCGATAGAGCGggatgacgacgacgaagaaGCGGAGGTTGATGAGGGGGAAGATGTGCCGGCTGCCAACACTTCGGCGGGCTCGCTCATCTCCAGCCAAACGGATGGCAATGGGGTTGTGGTGCGCGAATTTCTGGTGGATGAGGGCGACGGCACCGCCCAGACAATTGTCCTCGAAAATGAAGTGTACACCATATTGCCCTTGGAGGATGCCGCTGCCGGTGCTACCGAAGCGACGTCAGCAGAAGGCGATGTTAAGGCTGAGTCCAAGGAGAAGCAGAAACAGGCCGTGTCGCCAGTGGCCAAGAAGGAGCAACGGAAATCGTTGGCGGCCAGCTTGGCCGCTGCCATAGCGGATAATCAGGAGGAGCCGTTGAGCGACGATGATTTCAGTGGCGAAGTGCTCACCGAAGAGGATATAAAGCTCAAGGAGAACATAGCCAAGCTAATTGATATGCTCGTCGATCCGCAGACACTCAAGAAATACGGCTGGCCCAACAGCACCGAGGAGACGGTGCTCTGCAAGGTCATCGAGAACTGTGGCCACGATTTGGACAAGGGCGGCGAGAACTATGCCGAATTGGATTATGGCAGTCGCATGCGTGAATATTGCAAGCTCCTCTTCACGGTGGTCATACATAATGACTCGATAAAGTCGCTGCTCAACAATTTTCCCATCGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATCAGGATCTGGAGCAGAACCCGGACATGGAAAAGGATAAGGAAAAGGGCAAAGACATGGAGACTGAGCAATCAGACACGGACACTAGGCAGGATGCCGTTGAAACCGATGCCTAA
Protein Sequence
MSARKDASEANSLSSSSDGGGGNVVKILDVEKLTSAKDKRPGTRMKLLNDVTPSKAKISARVKQEKRTSIKILNNDDSASSPKGKGSSDRRSSGKAATAPPVVKILNEKRIAPTSTPVETAKIKTSPGKKKKMDHYVLQAIKSENSKSDNTTASIVEIEDDDDTIDFILADDDVELGVAKENDAEFIVSGVEEDDDDDDDEDEGTTEGTGTTNAGNNSELKEILEHVCGKCYKTFRRVKSLMKHLEFCRYDSGYHLRKADMLDNLEKIEKDALVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSECNDYPCSICNAKLRSGALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCSVCSQSFAVKEVLNRHMKRHTGERPHKCSECGKSFIQATQLRTHLKTHLRPFPCSKCTEKFKTEKQLQRHAKEHSRQKRRSFPCTICRRSFRTSALLQEHVDAGDHPLDKQVKVKRSAKTIERTDCAICDKNFDSTDTLRNHIRSVHECDPDDIFGTGPPRAKRRKKTVQFVAPIERDDDDEEAEVDEGEDVPAANTSAGSLISSQTDGNGVVVREFLVDEGDGTAQTIVLENEVYTILPLEDAAAGATEATSAEGDVKAESKEKQKQAVSPVAKKEQRKSLAASLAAAIADNQEEPLSDDDFSGEVLTEEDIKLKENIAKLIDMLVDPQTLKKYGWPNSTEETVLCKVIENCGHDLDKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDLEQNPDMEKDKEKGKDMETEQSDTDTRQDAVETDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01325058;
90% Identity
iTF_00511421;
80% Identity
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