Dmoj005454.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mojavensis
Gene Symbol
su(Hw)
Assembly
GCA_018153725.1
Location
JAECYD010000229.1:9603308-9607798[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00058 0.045 14.2 2.2 1 20 222 241 222 243 0.94
2 12 2.4e-06 0.00019 21.7 0.4 3 23 294 315 292 315 0.93
3 12 0.0069 0.54 10.9 0.2 1 23 321 343 321 343 0.96
4 12 6.5e-07 5e-05 23.5 2.5 1 21 350 370 350 371 0.95
5 12 2.8e-06 0.00022 21.5 0.6 2 23 383 404 382 404 0.96
6 12 9e-05 0.007 16.8 5.3 1 23 415 437 415 437 0.99
7 12 7e-05 0.0054 17.1 0.9 1 23 443 465 443 465 0.97
8 12 1.4e-05 0.0011 19.3 0.8 1 23 471 493 471 493 0.99
9 12 1.3e-06 0.0001 22.6 3.0 1 23 499 521 499 521 0.98
10 12 0.0028 0.22 12.1 1.4 1 23 525 547 525 547 0.97
11 12 1.5e-05 0.0012 19.2 0.2 1 21 555 575 555 579 0.92
12 12 4.9e-05 0.0038 17.6 0.3 3 23 599 620 597 620 0.96

Sequence Information

Coding Sequence
ATGAGCGCCAGCAAAGATGCCGCCGGCGCAGCACCTGCCACCAGCAAAGAGGCGAGCACACCCGTCATCAGAGTAATGGACGTGGATAAAATGGTTTCGCTGAAGGCGAAGCGAACTGGCACACGAATGAAGCTACTCAACGATGTGGCCGCAAAGGCCACTCGACCCAAGCAGGAGAAGCGCACCAGTATCAAGATACTCAACAACGATGAAGCCCAGGGCAGCTCGAAATCCGGTGAGAAGCGTGCCACGCCCAAAGCTGCCAGTCCAGGTGTGAAAATACTAAACGAGAAGCGAATTGGCCCCTCTGCCGCAGCAATGGAAACGGCCAAGATAAAAACATCGCCCAGCAAGAAGAAGAAGATGGACCACTACGTCCTGCAGGCCATCAAGAGCGAGAACAGCAAAGCGGACAACACGACAAGTGTCGTGGTGGTCGAGGATGATGACACCATTGACTTCATACTGGCCGACGACGATGTTGAGCTCGGCGATGCCGCCAAAGAGAATGGCGAAGAGTTTGTGGTGTCTGGTGTCGAGGATGATGATGACGACGATGACGATGATGATGACGATGAGGATGGACCAGGCGGCGGTGCTAGCGGAACAAAGCGCAAGAGCGGCAACAGCAACAACAACAACGAGCTCAAAGAAATGGTCGAGCACGTGTGCGGCAAGTGCTACAAGACATTCCGTCGCGTCAAGAGTCTGAAAAAACATTTGGAGTTCTGTCGCTACGACAGTGGCTACCATCTGCGCAAGGCGGAGATGCTGAAGAACCTGGACAAGATTGAGCGCGACGCCGTAGTTATGGAGAAGAAAGACATCTGCTTCTGTTGCAGCGAGAGCTACGATACCTTTCATCTGGGCCATATCAACTGTCCCGACTGTCCCAAGTCGTTCAAAACGCAGACGAGCTATGAGCGTCACATTTTCATCACGCATTCAGAATTCAACGATTTTCCATGCTCCATTTGCAATGCCAAGCTGCGCAGCTCTGCTCTGCTGAAGTTGCACGAACAGCAGCACCAGTCCAGGGGCAAGCCCTTCGCCTGCAAGATCTGCGGCAAGGACTTTACGCGCTCGTATCATCTTAAGCGCCATCAGAAGTATTCTTCGTGCTCGGCCAACGAGAACGACACCATGAGCTGCAAGGTGTGCGACCGTGTCTTCTATCGCTTAGATAATTTGCGCGCCCATCTCAAGCAGCATCTGGGCACCCAGGTGGTGAAGAAGCCGGAGTACATGTGCCACGTGTGCAAGAACTGCTTCTACAGTCTGTCTACGCTCAACATTCACATACGCACACATACGGGCGAGAAGCCGTTCGATTGCGATCTGTGCGACAAGAAGTTTTCGGCTTTGGTAGCCCTCAAGAAACACCGTCGCTATCACACGGGCGAGAAGCCTTATACCTGCACAGTGTGCAGCCAATCCTTTGCGGTGAAGGAGGTGCTCAATCGCCACATGAAACGGCACACGGGCGAGCGTCCGCACAAGTGCAACGAGTGCGGCAAAAGTTTCATACAGGCCACACAGCTGCGCACGCATTCCAAAACGCACCTGCGTCCCTACTCCTGCTCCTTGTGCATTCAGAAGTTTAAGACAGAGAAACAGCTCGAGCGCCATGTCAAGGAACACTCGCGTCAGAAACGTCCCTCGTTTCCCTGCACGGAATGCACACGAAGTTTCCGCACCAGCGCACTGCTCAAGGAGCACATGGACGCTGGCGATCATTCGCCTGCTAAGCCGACTCGGGCTAAACGTTCGGCCAAGGTGATCGAGCGCACGGACTGTGCCATTTGCGACAAGAACTTCGACAGCACTGACACTCTCCGTAATCACATACGCAATGTGCACGAGTGCGATCCGGATGATATTTTCGGCACAGAGCCCCCTGCCAAGCGCAAAGCTACCAAAAAGACCGTCGTGCTGGTCGATGACGAAGAGGAGGCGAACGAAGAGAAAGACCAGGATAAGGAAACGCCGGCTGCCAACACATCCGCTGGGTCACTCATCTCCAGCAAAACGGACGACAACGGAGTCGTGGTGCGTGAGTTCTTAGTGGATGAGGGCGATGGCAATGCTCAGACCATTGTGCTCGAGAACGAGGTGTACACCATATTGCCCTTGGAGGGTGCGGCCAGCACAGCCGAACCGACGGCTGAAGGCGGCGATGTCAAGGCCGAGTCCAAGGAGAAGCCACAGTCGGCTGTGTCGCCGACTGTCAAGAAGGAGCAGCGTAAATCCTTGGCCGCTAGCTTGGCCGCTGCAATTGCGGATAATCTGGATGACCCGTCCAGCGACGATGAGTTCAACGGCGAGGTTCTCAGTGAGGAGGATATTAAGTTGAAGGAGAACATTGCGAAACTGATCGATATGCTGGTCGATCCGCAGACACTCAAGAAGTACGACTGGCCCAACAGCTCCGAGGAGTCGGTGTTGTGCAAGGTCATCGAGAATTGTGGACACGATCTGGCCAAGGGCAGCGAAGCCTATGCCGAGTTGGACTACGGCAGTCGCATGCGTGAATACTGCAAACTCCTGTTCACTGTGGTCATTCACAATGATTCCATTAAGGCGCTGCTCAACAACTTTCCCATCGACGATGTTATTGAGTATGTGCTAGGCGATGAGGACCAGGACCAGGAGCAGGACCAGGATCAGGAGACAGACAAGGGCAAAGAGAAGGAGCATGATGGAGACAAATCGGACTCGGACAATAGACAGGATGAAGCTGACGCAGCTAAGGCCTAG
Protein Sequence
MSASKDAAGAAPATSKEASTPVIRVMDVDKMVSLKAKRTGTRMKLLNDVAAKATRPKQEKRTSIKILNNDEAQGSSKSGEKRATPKAASPGVKILNEKRIGPSAAAMETAKIKTSPSKKKKMDHYVLQAIKSENSKADNTTSVVVVEDDDTIDFILADDDVELGDAAKENGEEFVVSGVEDDDDDDDDDDDDEDGPGGGASGTKRKSGNSNNNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKAEMLKNLDKIERDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDFPCSICNAKLRSSALLKLHEQQHQSRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYSCSLCIQKFKTEKQLERHVKEHSRQKRPSFPCTECTRSFRTSALLKEHMDAGDHSPAKPTRAKRSAKVIERTDCAICDKNFDSTDTLRNHIRNVHECDPDDIFGTEPPAKRKATKKTVVLVDDEEEANEEKDQDKETPAANTSAGSLISSKTDDNGVVVREFLVDEGDGNAQTIVLENEVYTILPLEGAASTAEPTAEGGDVKAESKEKPQSAVSPTVKKEQRKSLAASLAAAIADNLDDPSSDDEFNGEVLSEEDIKLKENIAKLIDMLVDPQTLKKYDWPNSSEESVLCKVIENCGHDLAKGSEAYAELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQEQDQDQETDKGKEKEHDGDKSDSDNRQDEADAAKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01325058;
90% Identity
iTF_00502661;
80% Identity
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