Sred014034.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Scaptomyza reducta
Gene Symbol
su(Hw)
Assembly
GCA_035044485.1
Location
JAWNNV010001310.1:23847-26886[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00061 0.042 14.3 2.2 1 20 228 247 228 249 0.94
2 12 2.5e-06 0.00017 21.8 0.4 3 23 300 321 298 321 0.93
3 12 0.092 6.4 7.4 0.1 1 23 327 349 327 349 0.96
4 12 6.9e-07 4.7e-05 23.5 2.5 1 21 356 376 356 377 0.95
5 12 6.8e-06 0.00047 20.4 0.8 2 23 389 410 388 410 0.96
6 12 9.5e-05 0.0066 16.8 5.3 1 23 421 443 421 443 0.99
7 12 7.4e-05 0.0051 17.2 0.9 1 23 449 471 449 471 0.97
8 12 1.5e-05 0.001 19.3 0.8 1 23 477 499 477 499 0.99
9 12 1.4e-06 9.4e-05 22.6 3.0 1 23 505 527 505 527 0.98
10 12 6e-05 0.0041 17.4 0.9 1 23 531 553 531 553 0.95
11 12 9.5e-05 0.0066 16.8 0.1 1 20 561 580 561 585 0.93
12 12 4.6e-05 0.0032 17.8 0.3 3 23 604 625 602 625 0.96

Sequence Information

Coding Sequence
ATGAGCGCTAAAAAGGACACCACGGACGCGATCACTCTCGGCTCCAGCGGCGAAGGCGGAGGTACAGTGATCAAAGTCGTAGAGATTGAAAAGCTTTCAACAGCCAAGGACAAACGCACTGGCACACGCATGAAGCTTCTAAACGATGTAACTGCTGCTAAAGCCAAAACATCGCCCCGCATCAAGCAGGAGAAACGCACTAGTATCAAAATACTTAACAACGATGAATCAGCGATCAGTCCGAAAGGCAGCAGTGAGAGGCGCTCCGCTGGCAAACCAACAACTGGAAGTCCCACCGTCAAGATATTAAATGAGAAGCGTATTTCGGCCCCCTGTACGCCTGTGGAGACAGCCAAGATTAAGACATCGCCtagcaaaaagaagaaaatggaTCACTATGTGCTGCAGGCAATCAAGAGCGAAAACAGCAAATCGGAAAGCACGACGAACATCAGGGTGGAAATTGATGACGAGGATGATACGATTGACTTTATACTCGCCGACGATGACGCTGAATTGGGTGTGGCAAAAGAGAATGACGATGAGTTTGTTGTGTCTGCCGTGGAGgaggatgatgacgatgatgatgacgacgacgatgatgagggCACAGGTGACGGTGAGGGGAGTGGAAAAATCCGAAACGCTGGCAATAACAACGAACTCAAGGAAATGGTAGAGcatgtgtgtggcaaatgcTACAAGACATTCCGGCGCGTCAAGAGCCTTAAAAAACACTTGGAGTTTTGTCGCTATGACAGTGGCTATCATCTACGCAAAGCGGACATGCTGAAGAATCTGGAGAAGATCGAAAAGGATGCCGTTGTCATGGAGAAGAAGGACATATGTTTCTGCTGCAGCGAAAGCTACGACACCTTTCATCTGGGTCACATTAATTGCCCCGATTGCCCCAAGTCATTTAAGACACAGACCAGCTACGAGCGTCACATCTTCATAACTCACTCCGAGTTCAATGATTATCCCTGCTCCATTTGCAACGCTAAGTTGCGCAGCGGTGCTTTACTTAAACTGCACGAACAGCAGCATCAATTGCGTGGCAAGCCCTTTGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCGTACCACTTGAAGCGCCACCAGAAGTATTCGTCGTGCTCGGCCAACGAGAATGATACCATGAGCTGCAAGGTCTGCGATCGCGTCTTCTTTCGCCTCGACAATCTGCGCGCCCATCTCAAGCAGCATTTGGGCACTCAGGTGGTAAAGAAGCCTGAATACATGTGTCATGTGTGCAAGAATTGCTTCTACAGCTTATCAACGCTTAACATACATATACGCACTCACACTGGCGAGAAGCCTTTCGATTGTGATCTGTGCGACAAGAAGTTTTCGGCCTTGGTGGCGCTCAAGAAGCATCGTCGTTATCATACCGGCGAGAAACCTTACACCTGTACAGTGTGCAGTCAATCTTTTGCTGTTAAGGAGGTGCTTAATCGCCATATGAAACGGCACACGGGCGAACGTCCACACAAATGCAACGAGTGCGGCAAGAGTTTCATTCAAGCCACACAGTTGCGTACGCATTCCAAGACGCATTTGCGTCCCTTCGCCTGCACCAAATGCCCTGAAAAGTTCAAGACAGAGAAACAGCTCGAGCGTCACGGTAAGGAACATTCGCGCCAAAAACGACGCTCTTTTCCCTGTACGGAATGCTCACGGAGTTTCCGCACCAGTGCATTGCTTAAGGAGCACGTTGATGCTGGCGATCATTCGCCTAAACCTACGCGGGCAAAGCGTACTGCAAAGGCAATTGAGCGTACAGATTGCGCAATCTGCGACAAGAACTTCGATAGCACTGAAACGCTCAGGAACCACATACGTTCCGTGCACGAGTGTGATCCGGATGATATCTTTGGCACCGAGCCACCACCCGCTAAACGCAGGGCTAAGAAGTCCGTGCAGGTGTTGGAGACAATCGAAGGGGAAGACGAGGAAGATGAGGAAGACGCAGACGAGACGGGTGCCAACACGTCGGCGGCATCACTCATCTCCAGTAAAACGGATGGCAATGGAGTTGTGGTGCGCGAGTTTCTGGTGGATGAAGGCGACGGCAGCACACAGACAATTATGCTCGAAAATGAAGTGTATACGATTTTGCCATTGGAAGGTGCCGGTGCAACTGAAGGGTCGGCCGAAGGTGACCTCAAGGAAGAGTCTAAGGATAATCAAAAGGAGTCCGTATCACCCGTTGTCAAGAAGGAGCAGCGCAAATCACTGGCCGCAAGCTTGGCAGCTGCCATTGCGGATAATCAGGATGAGCCGTTGAGCGATGATGATTTCAGTGGTGAAGTGCTCACCGAAGAGGATCTTAAGTTGAAGGAGAACATAGCCAAGCTAATTGACATGCTGGTGGATCCAGacacacttaaaaaatatggCTGGCCCAACAGCCCCGAGGAGTCGGTCCTTTGCAAGGTCATTGAGAACTGTGGCTATGATCTGAACAAGGGTGGCGAGAACTATTCCGAATTGGATTATGGCAGTCGTATGCGCGAGTATTGCAAACTTCTGTTCACGGTGGTCATTCACAATGATTCCATCAAGGCACTACTGAACAATTTCCCCATTGACGATGTCATTGAATATGTGTTGGGTGATGAGGATCAAGACCAAGACATGGAAAAGGAAAAGGAGAAAGACAAGGAGACGCCCGATGCCGCTGAAGCTGAGGCTTAA
Protein Sequence
MSAKKDTTDAITLGSSGEGGGTVIKVVEIEKLSTAKDKRTGTRMKLLNDVTAAKAKTSPRIKQEKRTSIKILNNDESAISPKGSSERRSAGKPTTGSPTVKILNEKRISAPCTPVETAKIKTSPSKKKKMDHYVLQAIKSENSKSESTTNIRVEIDDEDDTIDFILADDDAELGVAKENDDEFVVSAVEEDDDDDDDDDDDEGTGDGEGSGKIRNAGNNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSGALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFFRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPFACTKCPEKFKTEKQLERHGKEHSRQKRRSFPCTECSRSFRTSALLKEHVDAGDHSPKPTRAKRTAKAIERTDCAICDKNFDSTETLRNHIRSVHECDPDDIFGTEPPPAKRRAKKSVQVLETIEGEDEEDEEDADETGANTSAASLISSKTDGNGVVVREFLVDEGDGSTQTIMLENEVYTILPLEGAGATEGSAEGDLKEESKDNQKESVSPVVKKEQRKSLAASLAAAIADNQDEPLSDDDFSGEVLTEEDLKLKENIAKLIDMLVDPDTLKKYGWPNSPEESVLCKVIENCGYDLNKGGENYSELDYGSRMREYCKLLFTVVIHNDSIKALLNNFPIDDVIEYVLGDEDQDQDMEKEKEKDKETPDAAEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01325058;
90% Identity
iTF_01328022;
80% Identity
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