Dmim012360.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimica
Gene Symbol
su(Hw)
Assembly
GCA_037043585.1
Location
JBAMBE010001187.1:22831-27160[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.00069 0.045 14.2 2.2 1 20 263 282 263 284 0.94
2 12 2.9e-06 0.00019 21.7 0.4 3 23 335 356 333 356 0.93
3 12 0.0098 0.63 10.6 0.1 1 23 362 384 362 384 0.97
4 12 7.8e-07 5e-05 23.5 2.5 1 21 391 411 391 412 0.95
5 12 3.4e-06 0.00022 21.5 0.6 2 23 424 445 423 445 0.96
6 12 0.00011 0.007 16.7 5.3 1 23 456 478 456 478 0.99
7 12 8.4e-05 0.0054 17.1 0.9 1 23 484 506 484 506 0.97
8 12 1.9e-05 0.0012 19.1 0.7 1 23 512 534 512 534 0.99
9 12 1.5e-06 0.0001 22.5 3.0 1 23 540 562 540 562 0.98
10 12 3e-05 0.0019 18.5 1.4 1 23 566 588 566 588 0.97
11 12 6.9e-05 0.0044 17.3 0.1 1 20 596 615 596 620 0.93
12 12 3.3e-05 0.0022 18.3 0.3 3 23 640 661 638 661 0.96

Sequence Information

Coding Sequence
ATGGCTGGTCCCATTTATTTCGGAACAGCTGATCGGCTGTGCACGAATCCAGTGAATAGTCAGACGCTAACGCCATTGTATACGTGCCTGCGATTGTGCTGTGAACTATCACTTCCAATGAGCGCGAGAAAGGACGCCTCCGAGGCGAACTCCCTCAGCTCCAGCAGCGATGGCGGAGGCAACGTAATCAAAATCTTGGATGTTGAGAAAATAGCATCAGTCAAGGATAAACGTCCTGGCACCCGCATGAAACTGCTCAACGATGTGACAGCGGCTAAGGCAAAAATCTCTCCACGCGTCAAGCAAGAGAAACGAAGCAGCATCAAAATACTCAACAACGATGATTTAGCAAACAGTCCCAAAGGCAGCAGCGAAAGGCGCTCCGCTGGCAAAGCAGCCGCTGCACCATCTGTCGTCAAGATCTTGAATGAGAAACGCATTGCGCCGACCTCGACGCCCGTGGACACGGCCAAGATTAAGACATCGCCCggtaaaaagaagaaaatggaTCACTATGTGCTGCAAGCCATAAAGAGTGAGAACAGCAAATTGGAAAATACGACGGCCAGCAGCGTGGAGATCGAGGATGATGACGATACCATTGATTTTATACTGGCCGACGACGATGTCGAGTTGGGTGCCGCCAAGGAGAACGACGATGAGTTCGTTGTCTCCGGTGTGGaggaagacgacgacgacgatgatgatgatgagggcACCGCAGAGGGCACTGGTGCAACGAATCGCAATGCCGGCAACAACAGTGAACTCAAGGAGATTTTGGAGCATGTGTGCGGCAAGTGCTACAAGACATTCAGGCGCGTCAAGAGCCTGAAAAAGCACTTGGAATTCTGCCGCTATGATAGTGGGTATCATCTGCGCAAAGCGGACATGCTCAACAATCTGGAGAAGATCGAAAAAGATGCTGTAGTTATGGAGAAGAAGGACATCTGTTTCTGCTGCAGCGAGAGCTACGACACCTTCCATCTGGGCCACATCAATTGCCCCGATTGTCCCAAGTCGTTTAAGACACAGACCAGCTATGAGCGACACATCTTCATCACTCACTCCGAGTGCAATGATTATCCATGCTCAATATGCAATGCGAAATTGCGCAGCGCCGCCTTACTCAAACTgcacgagcagcagcatcaattgCGTGGCAAACCCTTCGCCTGCAAGATCTGTGGCAAGGACTTTACGCGCTCGTACCACTTGAAGCGCCACCAGAAGTATTCATCGTGCTCGGCCAACGAGAATGATACCATGAGCTGCAAGGTATGCGATCGCGTCTTCTATCGCCTCGACAATCTGCGCGCCCATCTCAAACAGCACCTTGGCACCCAGGTGGTCAAGAAGCCAGAATACATGTGTCATGTGTGCAAGAATTGCTTCTACAGTCTGTCGACGCTCAACATACACATACGCACCCATACTGGAGAGAAGCCCTTCGATTGCGATCTTTGCGACAAGAAGTTTTCCGCATTGGTGGCGCTTAAGAAGCATCGACGCTATCACACCGGCGAGAAACCCTACACCTGTTCAGTGTGCAGTCAATCTTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAACGGCACACAGGTGAGCGTCCACACAAATGCAACGAGTGCGGCAAGAGCTTCATTCAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCTACCCCTGCTCCAAGTGCACCGAAAAGTTTAAGACAGAGAAACAACTCGAGCGTCACGTTAAGGAGCATTCGCGGCAGAAGCGGCGCTCCTTTCCCTGCTCGGAATGTCCCCGAAGTTTCCGCACTAGCGCCCTGCTGCAGGAGCATGTTGATGCTGGCGATCACTCACCTGATAAGCAGGTGAGGGCGAAGCGCTCGGCCAAGGCGATTGAGCGCACCGATTGCGCCATCTGCGACAAAAACTTTGACAGCACCGATACGCTGAGGAATCACATTCGCAGCGTGCACGAGTGCGATCCGGATGACATTTTTGGCACAGAGCCACCGCCCGCAAAGCGGCGGGCTAAGAAGACCGTTAAAGTTGTGGCACCGATAGAGCTTGACGACGAAGACGCGGAGGAGGATGATGGGGAAGATGTGCCGGCTGCCAACACTTCGGCCGGCTCGCTTATCTCCAGCCAAACAGATGGCAATGGGGTTGTGGTGCGCGAGTTTCTTGTGGATGAGGGTGACGGCAGCGCCCAGACAATTGTCCTCGAAAATGAGGTGTACACCATATTGCCCTTGGAGGGTGCCGCTGCCGGTGCTACTGAAGCGACGTCAGCTGAGGGCGATGTCAAGGCCGAATCCAAGGAGAAGCAGAAAAAGGCCGTGCCGCCAGTGGTCAAGAAGGAGCAACGGAAATCGTTGGCGGCCAGTTTGGCCGCTGCCATAGCGGATAATCAGGATGAGCCGTTGAGCGAAGATGATTTCAGTGGCGAGGTGCTCACCGAAGAGGATCTGAAGCTCAAGGAAAACATAGCCAAGTTAATTGATATGCTTGTCGATCCGCAGACACTCAAGAAATACGGCTGGCCCAACAGCACCGAGGAGTCGGTGCTCTGCAAGGTCATCGAGAACTGTGGCCACGATCTGGACAAGGGCGGCGAGAACTATGCCGAATTGGATTATGGCAGTCGCATGCGTGAATATTGCAAGCTCCTCTTCACGGTGGTCATTCACAACGACTCGATAAAGTCGCTGCTCAACAATTTTCCCATCGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATCAAGAGCAGGAACATGATCCGGACATGGAAAAGGACAAGCCAAAGGGCAAAGACAAGGAGACTGAGAAATCAGACACGGACACTAGGCAGGATGCCATTGAAATCGATGCCTAA
Protein Sequence
MAGPIYFGTADRLCTNPVNSQTLTPLYTCLRLCCELSLPMSARKDASEANSLSSSSDGGGNVIKILDVEKIASVKDKRPGTRMKLLNDVTAAKAKISPRVKQEKRSSIKILNNDDLANSPKGSSERRSAGKAAAAPSVVKILNEKRIAPTSTPVDTAKIKTSPGKKKKMDHYVLQAIKSENSKLENTTASSVEIEDDDDTIDFILADDDVELGAAKENDDEFVVSGVEEDDDDDDDDEGTAEGTGATNRNAGNNSELKEILEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLNNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSECNDYPCSICNAKLRSAALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCSVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYPCSKCTEKFKTEKQLERHVKEHSRQKRRSFPCSECPRSFRTSALLQEHVDAGDHSPDKQVRAKRSAKAIERTDCAICDKNFDSTDTLRNHIRSVHECDPDDIFGTEPPPAKRRAKKTVKVVAPIELDDEDAEEDDGEDVPAANTSAGSLISSQTDGNGVVVREFLVDEGDGSAQTIVLENEVYTILPLEGAAAGATEATSAEGDVKAESKEKQKKAVPPVVKKEQRKSLAASLAAAIADNQDEPLSEDDFSGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSTEESVLCKVIENCGHDLDKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEQEHDPDMEKDKPKGKDKETEKSDTDTRQDAIEIDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01325058;
90% Identity
iTF_00511421;
80% Identity
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