Basic Information

Insect: Scaptomyza polygonia
Gene Symbol: su(Hw)
Assembly: GCA_035044585.1
Location: JAWNNU010000151.1:7572845-7576750[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00065 0.071 14.2 2.2 1 20 269 288 269 290 0.94

2 12 2.7e-06 0.00029 21.7 0.4 3 23 341 362 339 362 0.93

3 12 0.065 7.1 7.9 0.1 1 23 368 390 368 390 0.96

4 12 7.4e-07 8e-05 23.5 2.5 1 21 397 417 397 418 0.95

5 12 7.3e-06 0.00079 20.3 0.8 2 23 430 451 429 451 0.96

6 12 0.0001 0.011 16.7 5.3 1 23 462 484 462 484 0.99

7 12 7.9e-05 0.0086 17.1 0.9 1 23 490 512 490 512 0.97

8 12 1.6e-05 0.0017 19.3 0.8 1 23 518 540 518 540 0.99

9 12 1.5e-06 0.00016 22.5 3.0 1 23 546 568 546 568 0.98

10 12 6.7e-05 0.0073 17.3 0.9 1 23 572 594 572 594 0.96

11 12 0.00058 0.063 14.3 1.4 1 20 602 621 602 626 0.93

12 12 1.4e-05 0.0015 19.5 0.3 3 23 645 666 643 666 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00065	0.071	14.2	2.2	1	20	269	288	269	290	0.94
2	12	2.7e-06	0.00029	21.7	0.4	3	23	341	362	339	362	0.93
3	12	0.065	7.1	7.9	0.1	1	23	368	390	368	390	0.96
4	12	7.4e-07	8e-05	23.5	2.5	1	21	397	417	397	418	0.95
5	12	7.3e-06	0.00079	20.3	0.8	2	23	430	451	429	451	0.96
6	12	0.0001	0.011	16.7	5.3	1	23	462	484	462	484	0.99
7	12	7.9e-05	0.0086	17.1	0.9	1	23	490	512	490	512	0.97
8	12	1.6e-05	0.0017	19.3	0.8	1	23	518	540	518	540	0.99
9	12	1.5e-06	0.00016	22.5	3.0	1	23	546	568	546	568	0.98
10	12	6.7e-05	0.0073	17.3	0.9	1	23	572	594	572	594	0.96
11	12	0.00058	0.063	14.3	1.4	1	20	602	621	602	626	0.93
12	12	1.4e-05	0.0015	19.5	0.3	3	23	645	666	643	666	0.97

Sequence Information

Coding Sequence: ATGATGTTAaggttaaatttttttggaacAGATGATCGGTTGAGTACGAAACCTGTGAATGGTAAGACGCCAGCGCCATTGTGTACGCTTACGTGCCTTTGCTCGTGCTACAAATTACGACTTTCAATGAGCGCCAAAAAGGACGCCAACGAGGCGACCCCGCTCGGCTCCAGCAGCAATGGTGGAGGCACAGTGATCAAAGTCGTAGATATTGAAAAACTTTCACCAGCCAAGGACAAACGCGGTGGGACTCGCATGAAGCTTCTCAACGATGTGAccgcaacaaaagcaaagacTTCGCCTCGCGTCAAGCAGGACAAAAGCACAAGCATCAAAATACTCAACAACGATGAATCAGCGATCAGTCCAAAAGGCAGCAGTGAGAGGCGCTCCGCTGGCAAAACAACTGTAAGCCCTGCCGTCAAGATATTGAACGAGAAGCGTATTTCGGCCCCCTCTACGTCTGTGGAAACAGCCAAGATTAAAACATCACCgggaaagaaaaagaaaatggaTCACTATGTACTGCAGGCCATTAAGAGTGAAAACAGCAAATCGGAAACCACGAACATCAGTGTGGAAATTGATGACGAAGACGATACTATTGATTTTATACTCGCCGACGAAGGTGCTGAATTGGGTGCGGCAAAGGAGAATGACGATGAGTTTGTTGTGTCTGCCGTGGGTGaaggtgatgatgatgacgatgaagaTGAAGACGACGAAGAAGAAATCACGGGTGATGTTGAGGAAGGAAAGAACCGAGTCGCTGGCACTAACAACGAACTCAAAGAAATGGTAGAGCATGTGTGCGGAAAGTGCTACAAGACATTTCGACGCGTCAAGAGCCTTAAGAAACACTTGGAATTCTGTCGCTACGACAGTGGCTATCATCTACGCAAGGCAGACATGCTCAAGAATCTAGAGAAAATCGAAAAAGATGCTGTGGTCATGGAGAAGAAGGACATATGTTTTTGCTGCAGCGAAAGTTACGACACCTTTCATctGGGCCACATCAATTGCCCCGATTGCCCCAAGTCATTTAAGACACAGACCAGCTATGAGCGTCACATCTTCATAACTCACTCCGAGTTCAATGATTACCCCTGCTCCATATGCAATGCTAAATTACGCAGCGACGCTTTACTAAAACTGCACGAACAGCAACATCAATTGCGTGGCAAGCCCTTTGCCTGTAAGATCTGTGGCAAGGACTTTACGCGCTCATATCACTTAAAGCGCCACCAAAAGTATTCGTCGTGCTCGGCCAACGAGAATGATACCATGAGCTGCAAGGTGTGCGATCGCGTCTTCTTTCGCCTGGACAATCTGCGCGCCCATCTCAAGCAGCATTTGGGCACCCAGGTGGTGAAGAAACCCGAATACATGTGTCATGTGTGCAAGAATTGTTTTTACAGCCTTTCTACGCTCAACATACATATACGCACCCACACTGGAGAAAAACCTTTCGATTGTGATCTGTGCGACAAGAAATTTTCGGCATTGGTGGCGCTGAAGAAGCATCGACGTTATCACACTGGCGAGAAACCGTATACCTGCACGGTGtgCAGTCAATCTTTTGCTGTTAAAGAGGTGCTAAATCGTCATATGAAACGTCATACGGGCGAACGCCCACACAAATGCAACGAGTGCGGCAAGAGCTTTATTCAAGCTACACAGTTGCGTACGCATTCCAAGACGCATTTGCGTCCTTTCGCCTGCAGCAAATGTCCTGAAAAGTTCAAGACAGAGAAACAACTCGAGCGCCACGGTAAGCTACATTCGCGACAAAAACGACGCACATTTACCTGTACAGAATGCTCAAGAAGTTTCCGCACCACTGCGTTGCTTAAGGAGCATGTTGATGCTTGTGATCATTCGCCGAAACCGGCACGGGCCAAGCGTACAAATAGGGTTATTGAGCGTACAGATTGCGCAATTTGCGACAAGAACTTCGATAGCACTGACACGCTTAGGAACCACATACGTACCGTGCACGAGTGCGATCCGGATGATATCTTTGGCACAGACCCACCACCTGCTAAACGCAGGGCCAAGAAAGCCGTGCAAGTGTTGGAGACAATCGAAGGGGAAGACGCGGAGGATGATGAGGACGAGACGGCTGCCAACACATCGGCGGGCTCCCTGCTCTCCAGCAAAACGGATAACAATGGTGTTGTGGTGCGCGAGTTTCTGGTTGACGAAGGCGACGGCAGCACACAGACTATTGTGCTCGAAAATGAAGTGTACACTATTTTGCCATTAGAGGATGCCGATGCAACTGAAGCGACAACCGGAGGTGGAGTCAAGGCAGAATCCAAGGACAAGCCAAAGCAGGCCGTATCACCAGTTGTCAAGAAGGAGCAACGCAAATCACTGGCTGCAAGTTTGGCAGCTGCCATTGCCGATAACCAGGATGAGCCGTTGAGCGATGATGATTTCAGTGGCGAGGTGCTCACTGAAGATGACCTTAAGTTAAAGGAGAACATAGCCAAGCTCATTGACATGCTGGTGGATCCAGAGACACTTAAGAAATATGGCTGGCCCAACAGCCCCGAGGAGTCGGTTCTATGCAAGGTCATCGAGAATTGTGGCCACGATCTGAACAAGAATGGCGAAAACTATTCCGAGTTGGATTATGGCAGTCGTATGCGCGAATATTGTAAACTTCTGTTTACCGTTGTCATTCACAATGATTCCATCAAGTCACTATTGAACAATTTCCCTATTGACGATGTCATTGAGTACGTTTTGGGTGATGAGGATCAGGACCAAGATCAAGACACGGAGAAGGACAAGGACAAAGACAAGGCAACAGAGAAACCAGAAAGAATCACTGCGACGCCAGAACCCGTTGAAGCCGAGgcttaa
Protein Sequence: MMLRLNFFGTDDRLSTKPVNGKTPAPLCTLTCLCSCYKLRLSMSAKKDANEATPLGSSSNGGGTVIKVVDIEKLSPAKDKRGGTRMKLLNDVTATKAKTSPRVKQDKSTSIKILNNDESAISPKGSSERRSAGKTTVSPAVKILNEKRISAPSTSVETAKIKTSPGKKKKMDHYVLQAIKSENSKSETTNISVEIDDEDDTIDFILADEGAELGAAKENDDEFVVSAVGEGDDDDDEDEDDEEEITGDVEEGKNRVAGTNNELKEMVEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLKNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSEFNDYPCSICNAKLRSDALLKLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFFRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCTVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPFACSKCPEKFKTEKQLERHGKLHSRQKRRTFTCTECSRSFRTTALLKEHVDACDHSPKPARAKRTNRVIERTDCAICDKNFDSTDTLRNHIRTVHECDPDDIFGTDPPPAKRRAKKAVQVLETIEGEDAEDDEDETAANTSAGSLLSSKTDNNGVVVREFLVDEGDGSTQTIVLENEVYTILPLEDADATEATTGGGVKAESKDKPKQAVSPVVKKEQRKSLAASLAAAIADNQDEPLSDDDFSGEVLTEDDLKLKENIAKLIDMLVDPETLKKYGWPNSPEESVLCKVIENCGHDLNKNGENYSELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQDQDQDTEKDKDKDKATEKPERITATPEPVEAEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01325058;
90% Identity: iTF_01324291; iTF_01322797;
80% Identity: -