Basic Information

Insect: Drosophila paucipuncta
Gene Symbol: su(Hw)
Assembly: GCA_035043875.1
Location: JAWNMP010000312.1:9353683-9358357[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0007 0.046 14.2 2.2 1 20 271 290 271 292 0.94

2 12 2.9e-06 0.00019 21.7 0.4 3 23 343 364 341 364 0.93

3 12 0.014 0.88 10.1 0.1 1 23 370 392 370 392 0.97

4 12 7.9e-07 5.2e-05 23.4 2.5 1 21 399 419 399 420 0.95

5 12 3.4e-06 0.00022 21.4 0.6 2 23 432 453 431 453 0.96

6 12 0.00011 0.0072 16.7 5.3 1 23 464 486 464 486 0.99

7 12 8.5e-05 0.0056 17.0 0.9 1 23 492 514 492 514 0.97

8 12 1.9e-05 0.0013 19.1 0.7 1 23 520 542 520 542 0.99

9 12 1.6e-06 0.0001 22.5 3.0 1 23 548 570 548 570 0.98

10 12 3e-05 0.002 18.5 1.4 1 23 574 596 574 596 0.97

11 12 4.1e-05 0.0027 18.0 0.1 1 21 604 624 604 628 0.90

12 12 3.4e-05 0.0022 18.3 0.3 3 23 648 669 646 669 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0007	0.046	14.2	2.2	1	20	271	290	271	292	0.94
2	12	2.9e-06	0.00019	21.7	0.4	3	23	343	364	341	364	0.93
3	12	0.014	0.88	10.1	0.1	1	23	370	392	370	392	0.97
4	12	7.9e-07	5.2e-05	23.4	2.5	1	21	399	419	399	420	0.95
5	12	3.4e-06	0.00022	21.4	0.6	2	23	432	453	431	453	0.96
6	12	0.00011	0.0072	16.7	5.3	1	23	464	486	464	486	0.99
7	12	8.5e-05	0.0056	17.0	0.9	1	23	492	514	492	514	0.97
8	12	1.9e-05	0.0013	19.1	0.7	1	23	520	542	520	542	0.99
9	12	1.6e-06	0.0001	22.5	3.0	1	23	548	570	548	570	0.98
10	12	3e-05	0.002	18.5	1.4	1	23	574	596	574	596	0.97
11	12	4.1e-05	0.0027	18.0	0.1	1	21	604	624	604	628	0.90
12	12	3.4e-05	0.0022	18.3	0.3	3	23	648	669	646	669	0.96

Sequence Information

Coding Sequence: ATGATGTTAATCGATAGTTCCCTGGTCTGGTCTGCTGCAGCGACCAGCTCTAATGCAGAAACAGCTGATTGGCTGTGCACGAATCCAGTGAATAGTCAGACGCTAACGCCATTGTATACGTGCCTGCAATCGTGCTGTGAACTATCACTTCCAATGAGCGCGAGAAAGGACGCCTCCGAAGCGAACTCCCTTAGCTCCAGCAGCGATGGCGGCGGCAGCGACGTTGAGAAAATAGCATCAGCCAAGAATAAACGTCCTGGCACCCGCATGAAACTGCTGAACGATGTGACAGCGTCTAAGACAAAATTCTCTGCACGCGTCAAGCAAGAGAAACGCACCAGCATCAAAATACTCAACAACGATGATTCAGCGAACAGTCCCAAAAGCAGCAGCGATAGGCGCTCCGCTGGTAAAGCAGCGACTGCAACACCTGGCGTCAAGATCTTAAATGAGAAACGTATTGCGCCACCCTCGACGCCCGTGGAGACGGCCAAGATTAAGACATCGCCCggtaaaaagaagaaaatggaTCACTATGTGCTGCAGGCCATCAAGAGTGAGAACAGCAAATTGGACAATACGACGACCAGCAGCGTGGAGATCGAGGATGATGACGATACCATTGATTTTATACTCGCTGACGACGATGTCGAGTTGGGTGCGGCCAAGGAGAACGACGATGAGTTCGTTGTTTCCGGTGTGGaggaagacgacgacgacgatgatgatgaggatgagggCACCGCTGAGGGCACTGGTACAACGAATCGCAATGCCGGCAACAACAGTGAACTCAAGGAGATTTTGGAGCATGTGTGCGGCAAGTGCTACAAGACATTCCGGCGCGTCAAAAGCCTGAAGAAGCACTTGGAATTCTGCCGCTATGACAGTGGGTATCATCTGCGCAAAGCGGACATGCTCAACAATCTGGAGAAGATCGAAAAGGATGCAGTGGTCATGGAGAAGAAGGAcatctgcttctgctgcagcGAAAGTTACGACACCTTCCACCTGGGCCATATCAATTGCCCTGACTGCCCCAAGTCGTTTAAGACACAAACCAGCTACGAGCGTCACATCTTCATCACTCACTCCGAGTGCAATGATTATCCATGCTCCATATGCAACGCGAAATTGCGCAGCGCCGCCTTACTCAATCTgcacgagcagcagcatcaattGCGTGGCAAACCCTTCGCCTGCAAGATCTGTGGCAAGGATTTTACGCGCTCGTACCACCTGAAGCGCCACCAGAAGTATTCGTCGTGCTCGGCCAACGAAAATGATACCATGAGCTGCAAGGTCTGCGATCGCGTCTTCTATCGCCTCGACAATCTGCGCGCCCATCTCAAACAGCATCTGGGCACCCAGGTGGTCAAGAAGCCCGAGTACATGTGTCATGTGTGCAAGAATTGCTTCTACAGTCTGTCGACGCTCAACATACACATACGCACCCACACTGGAGAGAAGCCCTTCGATTGCGATCTGTGCGACAAGAAGTTTTCCGCTTTGGTGGCGCTTAAGAAGCATCGTCGTTATCACACCGGCGAGAAACCCTACACCTGTTCAGTGTGCAGTCAATCTTTTGCCGTCAAGGAGGTGCTCAATCGCCACATGAAACGGCATACGGGCGAGCGTCCACACAAGTGCAACGAGTGCGGCAAGAGCTTCATACAGGCCACACAGCTGCGCACGCATTCCAAGACGCATCTGCGTCCCTACCCCTGCTCCAAGTGCACCGAAAAGTTTAAGACAGAGAAACAACTCGAGCGTCACGTCAAGGAGCATTCGCGGCAGAAGCGTCGCTCCTTTCCCTGCACGGAATGTCCACGAAGTTTCCGCACTAGCGCGCTGCTGCAGGAGCATGTTGATTCTGGCGATCACTCACCTGATAAGCAGGTGAGAGCCAAACGCTCGGCTAAGGCGATCGAGCGCACCGATTGCGCCATCTGCGACAAGAACTTCGACAGCACCGATACGCTGAGGAATCACATTCGCAGCGTGCACGAGTGCGATCCGGATGACATATTTGGCACTGAGCCACCGCCCGCAAAGCGACGGGCTAAGAAGACCGTCCAATTTGTGGCACCGATAGAGCAGGACGAGGACGACGAAGACGCTGAGCAGGATGAAAGGGAAGATGTGCCAGCTGCCAACACTTCGGCGGGTTCACTCATCTCCAGCCAAACGGATGGCAATGGGGTTGTGGTGCGCGAGTTTCTGGTGGATGAGGGTGACGGCACCGCCCAGACAATTGTCCTCGAAAATGAGGTGTACACCATATTGCCCTTGGATGGTGCCGCCTCCGATGCAACCGAAGCGAAATCAGCTGAGGGCGATGTCAAGGCCGAATCCAAGGAGAAGCAAAAACAGGTCGTGTCGCCAGTGGTCAAGAAGGAGCAACGGAAATCGTTGGCGGCCAGTTTGGCTGCTGCCATAGCGGATAATCAGGATGAGCCGTTGAGCGAAGATGATTTCAGTGGCGAGGTGCTCACCGAAGAGGATCTAAAGCTAAAGGAGAACATAGCCAAGCTAATTGATATGCTCGTCGATCCGCAGACACTCAAGAAATACGGCTGGCCGAACAGCACCGAGGAGTCGGTGCTCTGCAAGGTCATCGAGAACTGTGGCCACGATCTAGACAAGGGTGGCGAGAACTATGCCGAATTGGATTACGGCAGTCGCATGCGTGAATATTGCAAGCTCCTCTTCACAGTGGTCATACACAATGACTCGATTAAGTCGCTGCTCAACAATTTTCCCATCGACGATGTCATTGAGTATGTGCTGGGCGATGAGGATcaggaacaggagcaggacCCGGACATGGAAAAGGACAAGGACAAAGAAAAGGGCAAAGACAAGGAGACTGAGCAATCAAAAACGGACACTAGGCCGGATGCCGTTGAAACCGATGCCTAA
Protein Sequence: MMLIDSSLVWSAAATSSNAETADWLCTNPVNSQTLTPLYTCLQSCCELSLPMSARKDASEANSLSSSSDGGGSDVEKIASAKNKRPGTRMKLLNDVTASKTKFSARVKQEKRTSIKILNNDDSANSPKSSSDRRSAGKAATATPGVKILNEKRIAPPSTPVETAKIKTSPGKKKKMDHYVLQAIKSENSKLDNTTTSSVEIEDDDDTIDFILADDDVELGAAKENDDEFVVSGVEEDDDDDDDEDEGTAEGTGTTNRNAGNNSELKEILEHVCGKCYKTFRRVKSLKKHLEFCRYDSGYHLRKADMLNNLEKIEKDAVVMEKKDICFCCSESYDTFHLGHINCPDCPKSFKTQTSYERHIFITHSECNDYPCSICNAKLRSAALLNLHEQQHQLRGKPFACKICGKDFTRSYHLKRHQKYSSCSANENDTMSCKVCDRVFYRLDNLRAHLKQHLGTQVVKKPEYMCHVCKNCFYSLSTLNIHIRTHTGEKPFDCDLCDKKFSALVALKKHRRYHTGEKPYTCSVCSQSFAVKEVLNRHMKRHTGERPHKCNECGKSFIQATQLRTHSKTHLRPYPCSKCTEKFKTEKQLERHVKEHSRQKRRSFPCTECPRSFRTSALLQEHVDSGDHSPDKQVRAKRSAKAIERTDCAICDKNFDSTDTLRNHIRSVHECDPDDIFGTEPPPAKRRAKKTVQFVAPIEQDEDDEDAEQDEREDVPAANTSAGSLISSQTDGNGVVVREFLVDEGDGTAQTIVLENEVYTILPLDGAASDATEAKSAEGDVKAESKEKQKQVVSPVVKKEQRKSLAASLAAAIADNQDEPLSEDDFSGEVLTEEDLKLKENIAKLIDMLVDPQTLKKYGWPNSTEESVLCKVIENCGHDLDKGGENYAELDYGSRMREYCKLLFTVVIHNDSIKSLLNNFPIDDVIEYVLGDEDQEQEQDPDMEKDKDKEKGKDKETEQSKTDTRPDAVETDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01325058;
90% Identity: iTF_00511421;
80% Identity: -