Dham007678.1
Basic Information
- Insect
- Drosophila hamatofila
- Gene Symbol
- -
- Assembly
- GCA_035045345.1
- Location
- JAWNPA010000020.1:4996197-5003492[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.051 3.8 8.3 0.2 1 23 1326 1349 1326 1349 0.94 2 13 8.3 6.1e+02 1.4 0.2 1 23 1516 1538 1516 1538 0.91 3 13 0.00018 0.014 16.0 2.7 2 23 1541 1562 1541 1562 0.97 4 13 4e-05 0.003 18.1 0.2 3 23 1570 1590 1568 1590 0.98 5 13 5.9e-07 4.4e-05 23.9 4.1 2 23 1597 1618 1596 1618 0.97 6 13 5.6 4.2e+02 1.9 0.4 5 23 1631 1649 1629 1649 0.96 7 13 1.4 1e+02 3.8 5.4 3 23 1656 1677 1654 1677 0.93 8 13 0.15 11 6.9 0.2 2 23 1688 1708 1687 1708 0.96 9 13 5.7e-05 0.0042 17.6 0.4 1 19 1714 1732 1714 1736 0.95 10 13 1.6e-05 0.0012 19.3 0.5 1 23 1744 1766 1744 1766 0.98 11 13 0.00011 0.0079 16.8 7.6 1 23 1772 1794 1772 1795 0.96 12 13 0.00021 0.015 15.9 5.9 1 23 1800 1822 1800 1822 0.98 13 13 0.029 2.2 9.1 8.2 1 23 1828 1850 1828 1851 0.95
Sequence Information
- Coding Sequence
- ATGGTGGACAGTGTGCAGTGCCCCGTGTGCACGTTGTATCTGCACGCGGGCATGAATCTCTCCGATCATCTGGAGACACATCCCAAGGAACAGGTCATTAAGGCTCTAGTGCAAATGACCATTGTGAGCAACAATGGCATGGGCAGCGCCCTGGCAGCAGCTTTGCTCTCGGGCGATGGCGCCACCAGCTCCACCTCATTGTCAGCCACGAATGCGGTTGATGTCAAACCAGTTGTACCAGCATCttcaccaccaccagcaccacctccaccagcaacagctgcagctgcagcggcagcaactaaatcaacaacagccaaagctgcgttgcccagcagcagcagcagcaatagcagctgcggcaacaacaacaacaaattgagcaATCCACCGATAAAGGCATTAAAAAATGCGCCACCCACGACTGAGGCGCCAGCCAACACATCAAACACACCCACCACAAGCAGCGTGACCGCCATCTATTCCGACTATCGCTATGAACAGCAATCCCAGCAGACGCCAACGGCAACAGCTGCGGTGCATGGCTTTGCACGTGGTGCCACCACCACGCTGGTCATACCACAGGCaccccaacagcagcagcagcatcagtatCTGGCCTCACAGCAGCAGGCTGCTCACTTTGCCCAccttcagcaacagcagcagcagcagccggcgaTGAAGTACACCTATGCAGCAgcgctgccaccgccgccaccactGCAGCTCTTTGCGCAGCAGGCGACAGCAACGCAATCGCATCAGAAGCCCCCGCCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCACaaccaaaacaaacagcaacaacaacagcagcagcaacaacaacagcagcagcagcaacaacagcaacacataaCCTTGCAACATAACATTAACCTTGCACCAGCGAGTGGCAAGCATAGTAAACTCCACACGGATATCTTCCTGAatccaccgccaccgccaccgccacagCTCACGATGCCGTCAGCATTGTCGACTGCCTCACTAAGACTGCAATATCCGCCACAGCATCAACAGTCCcttgcagcagccagcagcagtagcaacagcagcggcggcggcagcagcagcagcagcaattatgCCGTGGCTAGCTGCTCCGCTGCCAGCTCCTCATCTGCCTTGATGTCCTCCATTGCCGTTGGGCGTGCTAGCAGCAGTCGTCAGGCAACCAATTCCCCCTTTGGTGCGCTGCTGAATGCTGCGGCGCAAGCTGCCTGCGCCTCGCCCGCCTCGTCCAGTGCGTCCGTGCTGCGCTACGCCGAGTCGCCAGTGGCTCACTACTTGGAGCGAGACAACGGCGACTTCATAGTCCAGGAGACGCCAAAGCACATTGTCGAGTGCGTGGAGAAGGAGGACGGAGAGTTCTCTGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTGCTGCACATACACGACGATGACGAAGACGACGAAGAGGAagacgaggaggaggatgacAAGGGCTGGGCCAACAGCGATGCAGAGGATCATTTGAAGATGGAGGATCATGTGGAGGATGGCGACGATGAGCACGAGGATAGCCGCAGCAGAGCTtcacacaaaacaacaacgaaaaagtCACGCAAAGCAAAGGGTAATGGCCGTAAGCACAAAAGGGTCAACAAGCATCAGCCGGACGATGAGGATGACTTCATGAGCATAGGCAGCAGCTGCGCCGAGAGCGATcatcagctggagcagcagcaacaagcgcAGCAATCACATGTGCCACAGGCTGCGTCGCCAGCGCCTGGTCAACTATCCACGGCGCCGTCGACGAGCAGTggagcagccgctgctgcagccgccgccgccgccgcctccagcACCAACTCGAACAAGTCGAAGAAGAATCGTGTGACAGTGCTCAGCGATGTGCCGCTCAACATGAACGAGTATCTGGATCTAGTGGGCAACATTGTGGCTTCCAGTCGGATTAGTGCCACGCGTCCGTTTGCCGCTGTGGCGCCCATACCTTTGGTCAAGGTGGAGAAGGAGGAGCCCATGGATGACTACGACACTGTCAGGGACGAGATGCAAGCCATGGAGCAGAAGCATAGCCTGGAGCAtgccagtggcagcagcagcagcaacagtggaCATGGCACCACCAGTGTCATCCGAATGGCCAGCActagcagcagcggcgcagccgccaccaccaccagcaacacAAATGTGGCCAACGACGATCTCACGCAGCCGCCGCCCATGAAGGTGGAGGTGGAGCCGACGGTGTTGCTGCCGCAACGCTTCTCGGCGCCGGCACAGCATCGCGGGCCCAAGAAGTTAGTCATCAAGCCAAAGGCCACAGGAACGGCGTCGACGTCGGCAACGACCAAAAAGACTGATAACAgcgccgccagcagcagcagcggcaacggcagcaactgcGCCGAGCCACTCAGCATATCATCGAAGACACCCGCAGAGCCGTTACAGATCAAGAGCGAGACTGGGGAGCATGTCTccagcagtggcagtggcagtggcagcataTTGGAGAAGCATCTGACCAACAGCTATGCCGCCCAGCAGGCGCGCAAGCACTCGTCAGTAAACGACGACGATGCCCGTGTGCTGCTCGAGTTTGCCAACtcgaagcagcagccgccggcGGGCAACAGCAATCAGACGACGTTTGTGGTGAATGCGGCCAGCTTTGCCTCGGCGGGCTCTGTCTTtgccagcggcagcagcagcagcgtgcCGAAGTCAGCTAAGCCGGGCGACGAGTACATTCTGCCAGATAACAATCTAGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCGACTCGCAGcacgagcagctgcagcagcagcagcagtcacagcaatcgcagcagcagcagcagtcggcagCGCAGCAAGCCATGCAGCAGCCGTCCTCCTTTACGGACTTCAATTTCCTCTACCATCAGCATGGAAccgcaacaactgcagcagcagcagcagcaacgacggcggcagcaacagcaactgcctCAACCTTTGCACCATTTggcatgcaacagcagcagcagcagcaagtgctGCAGCATCCACAGCACGGCTCGAGCGAGGCCACCAATGCCGCCACGCTGGCCTCCTCCTCCAGCAACTCATCTGTGCTGGATCAGGATTGCTCCATGAATGCCACGTTTCGCGTGGGCAAACAGCAATCCACAATGGCTTCATGGTATCAGCCAcagtcgcagccacagccacaagcCAGCACTTCACACAGCTCCAATGTGGATCAGTCCAGCAACTTCATTGCCGCACTTGCCGCTGTGGAATGCTGCAGTGTGGCAGCCGTGGACAGCGATGTGAGCGAGGCCAAGTACTTGGATCTGGATGCCTGCAAGCGGGAACAGCtaagcaatagcagcagccacTTGCCCTCGGCCTCTGCATCCACCACATCCTCATCCTTTGCGGCCGCCGCCACGGAGAGCAGCCTGGTGGGTGGCCTGGGTCTGAACATACGCACCGATGAGAAAATGCCTGCCAAGGGCGAAATCTCCGAGCAGGAGAGCAACTGTGACATTGAGAACTCCTGGAGTCAATCGATGTACGGCGACTTGTCACAGCGTTACTTTAGGAATCAGTTTGCAGATGGCTACAATCAGCAGCTGGCCGATTGGCGCCACGATTACTATCCGGCGCAGGATCTcagtggccagcagcagccggagcgTGAGCAGAAGCGCTTTGACTTCAACGCTGTCGCCGCGGAGTATGCGCATCCGGGCCAGCTGGATGCTTCCCAGAGTTCGACTAGAAACAATCATTTGCTAGATGCACAGCCCACCActtcctcgtcgtcgtcggcatTGCTGGCTGGTCCACCAATAGCCTCGACATCGCGTGCCGCTGCCGAAGCGGAGGCTGTGGCCGCCGCTCTGGCGCAGCGGAAGCCGCCGCGTCGCAAGATCTACAAGTGTCCGCACTGCGTGGCCATCTTCGAGAAGCTGAAGGAGCGCAATGCGCATATGATTGGCGAGCACAACTATGTGCGCCAGAATCGACGCCTCATCTGCACGCAGGCTTTGGTCAACAGCAGCTTGGCAGATccgcaggagcagcaggcgcagggacaacagcagcagcagcatcagcatcaattGCTGCAGGCAGCGGGCCACAGTAATGGCGACATTATGCACGAGGATTCCAAGGATGGCATTGTAAAGATTAAGCAGGAGCACTGCCACGATAAGGCGGATACCTCCGAGCAACTGCTGGGTCATTCAGAGCTGCCCGACGTCAAGGATTCCGGCCTCCTCAATGCCAACGATGAGAGCGGTCGCGATGCGGACATGAAGCCGCCCGCAGGCGTCACAGATCTGGACGAGAAGCCGACCATACCGCCGCTGGCCATGACCACGCCGGCGGCCAAGCTGGCTGCTCTGTACCGTATGCTCATCGCGTACAACGAGTCCAAGCTGGGCCAGGAGCGCAACAATCTCAGCGAGCTGGAGCAAAAGGCCATGGAGAAATCGATATTCCTATGCTACGTGTGCCGCACCGATTTTCCCTCTGTCAAGCTGTACGATGCCCATCTGACTGAGCATCCTGCCGAGTGCTTTACCTGTGGCAAGAAATTCTATCGCTGGAAGAACTTCTCGCTGCATCTGAAGCGCCATCTGGGCTGGAAGGAATTCGGCTGCTACATCTGCGACAAGAAGTTCGTGGTGCGCAGCGCCCTGGTGGAGCACATGCGCATGCACACGGGCCAGACGCCGCTCAAGTGTAAAATATGCGGCAAAAAGTTCAAACGATATTCCAATCTTACACAACATCGCAAGCGTCACACCAAGATCCTGGTGCGCAAGAAGGAGTATGTGTGCCACTGCGGCGAGGTGTTGCCGTCGAAGGCGCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAGTGTTGTCCCTATTGCTGCGATCGCTTTGTGCACGCCAACTCGCTGCGCCGGCACATTCGCTTGGCCCACTCGGATAAGTTTGACTACGCTGAGCCCATGGAGTGCCCCATGTGCAAGCAAATCTTTGCCAAGACCTCGATCAAGGCGCACATGGCGACGCATTCGACTGATCCGCAATACGATTGCGCCATATGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCGAATCGCACAGCCAAGCCGTTCAAGTGCGAGTACTGCCCCAAGGCTTTTGTGCGCGAGCTGGACTTCAAGAATCACATGAATGCCCATAAGCAGATCAAGCCCTACACTTGCGAGTACTGCGGCTGCAAGTTCATACGCAAGTACAACTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAGTCTTTCCATCGGCATTACTATCTGATTGAGCATCGGCGCATCCATACTGGCGAGCGTCCCTTCCACTGCACCATCTGTGGCAAGAGCTCGACGACAAAGACCAATCATAATAAGCATCTGAAGATACATCATTCACGGGATCCATTCACCGTGGAggtttaa
- Protein Sequence
- MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVSNNGMGSALAAALLSGDGATSSTSLSATNAVDVKPVVPASSPPPAPPPPATAAAAAAATKSTTAKAALPSSSSSNSSCGNNNNKLSNPPIKALKNAPPTTEAPANTSNTPTTSSVTAIYSDYRYEQQSQQTPTATAAVHGFARGATTTLVIPQAPQQQQQHQYLASQQQAAHFAHLQQQQQQQPAMKYTYAAALPPPPPLQLFAQQATATQSHQKPPPAYGAAISQIRSQHNQNKQQQQQQQQQQQQQQQQQQHITLQHNINLAPASGKHSKLHTDIFLNPPPPPPPQLTMPSALSTASLRLQYPPQHQQSLAAASSSSNSSGGGSSSSSNYAVASCSAASSSSALMSSIAVGRASSSRQATNSPFGALLNAAAQAACASPASSSASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEEEDEEEDDKGWANSDAEDHLKMEDHVEDGDDEHEDSRSRASHKTTTKKSRKAKGNGRKHKRVNKHQPDDEDDFMSIGSSCAESDHQLEQQQQAQQSHVPQAASPAPGQLSTAPSTSSGAAAAAAAAAAASSTNSNKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRISATRPFAAVAPIPLVKVEKEEPMDDYDTVRDEMQAMEQKHSLEHASGSSSSNSGHGTTSVIRMASTSSSGAAATTTSNTNVANDDLTQPPPMKVEVEPTVLLPQRFSAPAQHRGPKKLVIKPKATGTASTSATTKKTDNSAASSSSGNGSNCAEPLSISSKTPAEPLQIKSETGEHVSSSGSGSGSILEKHLTNSYAAQQARKHSSVNDDDARVLLEFANSKQQPPAGNSNQTTFVVNAASFASAGSVFASGSSSSVPKSAKPGDEYILPDNNLEVDEIVISSSSSYASDSQHEQLQQQQQSQQSQQQQQSAAQQAMQQPSSFTDFNFLYHQHGTATTAAAAAATTAAATATASTFAPFGMQQQQQQQVLQHPQHGSSEATNAATLASSSSNSSVLDQDCSMNATFRVGKQQSTMASWYQPQSQPQPQASTSHSSNVDQSSNFIAALAAVECCSVAAVDSDVSEAKYLDLDACKREQLSNSSSHLPSASASTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDLSQRYFRNQFADGYNQQLADWRHDYYPAQDLSGQQQPEREQKRFDFNAVAAEYAHPGQLDASQSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNSSLADPQEQQAQGQQQQQHQHQLLQAAGHSNGDIMHEDSKDGIVKIKQEHCHDKADTSEQLLGHSELPDVKDSGLLNANDESGRDADMKPPAGVTDLDEKPTIPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYICDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKILVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00520097; iTF_00502703; iTF_00582433; iTF_00509988; iTF_00479654; iTF_00540550; iTF_00572774; iTF_00496039; iTF_00476808; iTF_00598344; iTF_00544682; iTF_00493836; iTF_00532557; iTF_00546829; iTF_00512912; iTF_00589009; iTF_00568434; iTF_00545427; iTF_00561203; iTF_00559670; iTF_00599766; iTF_00573497; iTF_00551772; iTF_00554557; iTF_00547550; iTF_00473247; iTF_00567712;
- 90% Identity
- iTF_00544682;
- 80% Identity
- -