Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:970933-980234[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.042 2.4 8.3 0.2 1 23 1323 1346 1323 1346 0.94

2 13 6.8 3.9e+02 1.4 0.2 1 23 1510 1532 1510 1532 0.91

3 13 0.00015 0.0087 16.0 2.7 2 23 1535 1556 1535 1556 0.97

4 13 3.3e-05 0.0019 18.1 0.2 3 23 1564 1584 1562 1584 0.98

5 13 4.9e-07 2.8e-05 23.9 4.1 2 23 1591 1612 1590 1612 0.97

6 13 4.6 2.6e+02 1.9 0.4 5 23 1625 1643 1623 1643 0.96

7 13 1.1 65 3.8 5.4 3 23 1650 1671 1648 1671 0.93

8 13 0.12 7 6.9 0.2 2 23 1682 1702 1681 1702 0.96

9 13 4.7e-05 0.0027 17.6 0.4 1 19 1708 1726 1708 1730 0.95

10 13 1.3e-05 0.00076 19.3 0.5 1 23 1738 1760 1738 1760 0.98

11 13 8.8e-05 0.005 16.8 7.6 1 23 1766 1788 1766 1789 0.96

12 13 0.00017 0.0097 15.9 5.9 1 23 1794 1816 1794 1816 0.98

13 13 0.024 1.4 9.1 8.2 1 23 1822 1844 1822 1845 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.042	2.4	8.3	0.2	1	23	1323	1346	1323	1346	0.94
2	13	6.8	3.9e+02	1.4	0.2	1	23	1510	1532	1510	1532	0.91
3	13	0.00015	0.0087	16.0	2.7	2	23	1535	1556	1535	1556	0.97
4	13	3.3e-05	0.0019	18.1	0.2	3	23	1564	1584	1562	1584	0.98
5	13	4.9e-07	2.8e-05	23.9	4.1	2	23	1591	1612	1590	1612	0.97
6	13	4.6	2.6e+02	1.9	0.4	5	23	1625	1643	1623	1643	0.96
7	13	1.1	65	3.8	5.4	3	23	1650	1671	1648	1671	0.93
8	13	0.12	7	6.9	0.2	2	23	1682	1702	1681	1702	0.96
9	13	4.7e-05	0.0027	17.6	0.4	1	19	1708	1726	1708	1730	0.95
10	13	1.3e-05	0.00076	19.3	0.5	1	23	1738	1760	1738	1760	0.98
11	13	8.8e-05	0.005	16.8	7.6	1	23	1766	1788	1766	1789	0.96
12	13	0.00017	0.0097	15.9	5.9	1	23	1794	1816	1794	1816	0.98
13	13	0.024	1.4	9.1	8.2	1	23	1822	1844	1822	1845	0.95

Sequence Information

Coding Sequence: ATGGTGGACAGTGTGCAGTGCCCCGTGTGCACGCTTTATCTGCATGCGGGGATGAATCTCTCCGATCATTTGGAGACACATCCAAAGGAACAGGTCATCAAGGCTCTGGTGCAAATGACCATTGTTAGCAACAATGGTATGGGCAGCGCCCTTGCAGCAGCATTGCTCTCTGGTGATGGCGCCACTAGCTCCACCTCATTGTCATCCACGAATGCGGTTGATGTCAAACCAGTTGTACCAGCATCTTCACCACCacctccaccaccaccaataacaccaacagcagcagcagcacctgctgcagttgcagtggcaacggcagcaactaAATCAACAGCACCCAAAAATGCGttgcccagcagcaacagcagcagtagcagtagcaacagcaacagcaacagcagctgcggcaacaataacaaattgagCAATCCACCGATAAAGGCAGTAAAATGCGCGCCACCTACGACTGAGGCGCCAGCCAACACATCAAATACACCCACCACAAACAGCGTGACCGCCATCTATTCCGACTATCGCTATGACCAGCAATCCCAGCAGGTaacgccaacagcaacaactacggTGCATAGCTTTGCACGTGGTGCCACTACGCTGGTAATACCGCAAGCAacacaccagcagcagcaacagcatcagtaTCTGGCCTCACAGCAGCAGGCTGCCCATTTTGCCCAccttcagcaacagcagcaacagcatcagccgGCCATGAAGTACACCTAtgcagcagcgctgccaccACTGCAGCTCTTTGCGCAGCAGGCGACATCAACGCAATCACATCAGAAGCCACCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCACAACcaaaataaacagcaacaacaacaacaacaacagcaacaacaacaacaacagcagcagcaacaacaacaacagccgccgcAACAACACATAACCTTACAACATAACATAAACCTTGCACCACCGAGTGGCAAACATAGTAAACTTCACACGGATATCTTCTTGAatccaccaccaccaccaccgccacagCTCACAATTCCGTCAACATTGTCGACTGCCTCATTAAGACTGCAATATCCGCAACAGCATCCACAAGCCCTTAcaggcagcagtagcagcaacagcagtagtaATTATGGGGTAGCTAACTGCGCCTCTGCTAACTCCTCGTCTGCATTGATGTCATCCATCTCCGTCGCACGTGCAAGCAGCAGTCGCCAGACAACCAATTCACCTTTTGGTGCGCTGCTAAATGCTGCAGCGCAAGCTGCATGCGCCTCTCCCGCCTCATCCAGTGCATCTGTACTGCGATATGCCGAATCGCCAGTGGCTCACTATTTGGAGCGGGATAATGGCGACTTCATAGTCCAGGAAACTCCCAAGCATATTGTCGAATGTGTTGAGAAGGAAGACGGCGAGTTCTCAGTGATTGAACGCATCTATCAGTCACCACCTAGCGTACTGCACATACACGACGATGACGAAGACGACGAAGAGGAAgacgaggaggaggatgaCAAGGGGTGGGCTAACAGCGATGTTGAGGATCACATGAAGATGGATGATCATGTTGAAGATGGGGACGATGAGCACGAGGATAGTCGGAGCAGAGCTTCTCACAAAGCTACAACGAAAAAGTCTCGCAAAGCAAAAGTAAGTGGAAGAAAGCACAAACGCATCAACAAGCATCAACCGGACGATGAGGATGACTTTATGAGCGTAGGTAGCAGCTGCGCTGAAAGCGAACATCAGttagagcagcagcatcagacGCAGCAGACACATGTGCCACAGGTGGCATCCCCCACGCCAGGTCAACTTTCCACGGCGCCTTCAACGAGCAGTggagcggctgctgctgctgtcggtgCTTCCTGCAGTACCAACTCGAACAAATCCAAAAAGAATCGTGTAACAGTACTCAGCGATGTTCCGCTAAACATGAACGAGTATTTGGATCTAGTGGGCAACATTGTAGCCTCTAGTCGCATTGGCGCTACTCGTccttttgctgctgtggcgCCCATACCATTGGTCAAGGTAGAGAAGGAGGAGCCAATGGATGATTACGATACCGTAAGAGACGAGATGCAAGCTATGGAGCAAAAGCACAACATGGAGAATGCTAGtggcagcagtaacagcagcaacagtggtCATGGCACCACCAGCGTCATACGAAtggccagcaccagcagcaccaccaccaccacaaaTGTTGCCAACGACGATCTCACACAGCCGCCGCCAATGAAAGTGGAGGTGGAGCCAACGGTGCTACTACCGCAACGTTTCTCAGCGCCAGCGCAGCATCGTGGGCCTAAGAAGTTAGTCATCAAACCAAAGGCTACAGtgacggcggcagcagcatcgaCGGCAACGACTAAAAAGACTGATAACaacgctgccagcagcagcaactgcgccGAAACACTCAGCATATCATCAAAAGCATCCCCAGAGCCGTTGCAGATCAAAAGCGAGAATGTTGAGCATGCTCCCACAAGTGGCAGCATTTTGGAGAAACATCTAACCAATAGCTTCGCCGCACAACAGGCACGCAAACACTCTGCGGTCAACGACGACGATGCACGCGTGCTGCTTGAGTTTGCCAACTCAAAGCAGCAGCTTCCGCCGGGCAATAGCAATCAGACTACATTCGTGGTAAATGCGGCCAGTTTTGCTTCGGCTGGCTCTGTATTTGCGAGTGGTAGTAGCAACGTTCAGAAGTCAACTAAGCCGGGCGATGAATACATTCTGCCAGATAATAATCTAGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCGATTCGCAGCACgaacaattgcagcagcagcagcagtcacagcaatcgcagcagcagcaacagcagccgccagCGCAGCAAGCCttgcagcagtcgcagcagccgTCCTCCTTTACAGATTTCAATTTTCTGTACCATCAACATggcacaacaactgcagcggcaacatcgacggcagcagcaacatcaactgcCACAACCTTTGCTCCATTTGgtatgcagcaacagcagcaggtgctgcAACATCCACAGCATGGCTCGAGCGAAGCAACCAATGCTGCCACGCTGGCCTCCTCCTCTAGTAACTCATCAGCTTTAGATCAGGATTGCTCCATGAATGCAACGTTTCGAGTTAGCAAACAACAGTCCACAATGGGTCCCTGGTatcagccacagccgcagcaacagccacaggcGAGCACGTCACACGGTTCCAGTGTGGAGCAGTCAAGCAATTTTATTGCTGCACTTGCAGCTGTTGAGTGCTGCAGCGTTGCGGCCGTGGATAGCGACGTGAGCGAAGCCAAGTATTTGGACCTGGATACCTGTAAGCGGGAACAATtgagcaatagcagcagccaTTTGCCTTCGGCCTCTGCGTCCACCACATCCTCGTCATTTGCAGCCGCCGCCACGGAGAGCAGTTTGGTTGGTGGCTTGGGCTTGAACATACGCACTGATGAGAAAATGCCCGCCAAGGGTGAAATTTCCGAGCAGGAAAGCAATTGTGACATTGAAAACTCCTGGAGTCAATCGATGTACGGCGACTTATCACAGCGTTACTTTAGAAACCAGTTCACGGATGGTTATAATCAGCAGCTGGCCGATTGGCGTCACGATTACTATCCGGCGCAGGATCTcagtggccagcagcagccagagcgtGAGCAAAAGCGCTTCGATTTTAACGCGGTCGCTTCGGAGTACACGAATCCGGGTCAGTTGGATACATCCCCAGGCTCAACTAGAAACAATCATTTGTTGGATGCACAGCCCACCAcctcctcgtcgtcgtcaGCTTTGCTGGCTGGTCCACCAATAGCTTCGACATCGCGTGCTGCTGCCGAAGCGGAGGCCGTGGCTGCAGCGCTGGCGCAACGGAAGCCACCGCGTCGCAAGATCTACAAGTGTCCGCACTGTGTGGCCATCTTTGAGAAGTTAAAGGAGCGTAACGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGACGTCTCATCTGCACACAGGCCTTGGTCAATACCACATTGGTCGACCCACAGGAGCAGGAGTCACagggacaacagcagcagcgtcaatTGCTGCAGGCAGCGGGGCACAGCAATGGAGACATTGTGCATGAGGATTCCAAGGATGGCATTATAAAGATCAAGCAGGAACACTGCCACGATAAACAGGATGCTTCTGAGCAACTACTTGCCCATTCAGAGCTGCCTGATGTGAAGGATTCCGGGCTACTCAATGGTAGCGATGAGAACGGTCGCGATGCAGACATGAAGCCCCCAGCCGGCGTCACAGACTTGGACGAGAAGCCAGCCATACCGCCGTTGGCTATGACAACACCAGCTGCCAAGCTTGCTGCTCTATATCGCATGCTGATTGCATACAATGAGTCCAAGCTGGGCCAGGAGCGAAACAATCTCAGCGAACTTGAGCAAAAGGCCATGGAAAAATCCATATTTTTATGCTATGTATGCCGCACTGATTTCCCCTCTGTGAAGCTGTACGATGCTCATTTGACTGAGCATCCCGCAGAGTGTTTCACCTGTGGCAAAAAATTCTATCGCTGGAAGAACTTTTCGCTGCATCTGAAACGTCATTTGGGCTGGAAGGAGTTCGGCTGTTATATCTGCGACAAGAAATTCGTGGTGCGCAGTGCTCTTGTGGAGCACATGCGCATGCACACGGGCCAGACACCGCTCAAGTGTAAGATATGCGGCAAAAAGTTCAAGCGATATTCGAACTTAACACAGCATCGAAAGCGTCACACTAAGATTTTGGTGCGAAAGAAGGAGTATGTGTGTCATTGTGGCGAGGTGTTGCCGTCTAAGGCACGCTTCTTGTGGCATAAGGAAACCCACGACTTGAAGCCCAAATGCTGTCCCTATTGTTGCGATCGTTTTGTGCATGCCAATTCGCTGCGAAGGCACATTCGACTGGCACACTCGGATAAGTTTGATTATGCTGAGCCCATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAAACCTCAATTAAGGCGCACATGGCAACGCATTCGACAGATCCGCAATACGATTGCGCCATATGCAACAAGAGCTTCTCCACAAAATGGAACCTCAAGATCCATTCGTGGGTACATGCAAATCGCACAGCCAAACCGTTCAAATGCGAATACTGCCCAAAGGCTTTTGTGCGCGAGCTGGACTTCAAGAACCACATGAACGCACACAAGCAGATCAAGCCATACACTTGCGAATACTGTGGCTGCAAGTTCATACGCAAATACAATTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGTGACAAGTCTTTCCATCGGCATTATTATCTAATTGAGCATCGGCGCATCCATACGGGCGAGCGTCCGTTCCATTGTACCATCTGTGGCAAGAGTTCGACGACAAAGACCAATCATAATAAGCATCTGAAGATACATCATTCACGGGATCCATTCACCGTGGAGGTTTAA
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVSNNGMGSALAAALLSGDGATSSTSLSSTNAVDVKPVVPASSPPPPPPPITPTAAAAPAAVAVATAATKSTAPKNALPSSNSSSSSSNSNSNSSCGNNNKLSNPPIKAVKCAPPTTEAPANTSNTPTTNSVTAIYSDYRYDQQSQQVTPTATTTVHSFARGATTLVIPQATHQQQQQHQYLASQQQAAHFAHLQQQQQQHQPAMKYTYAAALPPLQLFAQQATSTQSHQKPPPAYGAAISQIRSQHNQNKQQQQQQQQQQQQQQQQQQQQQPPQQHITLQHNINLAPPSGKHSKLHTDIFLNPPPPPPPQLTIPSTLSTASLRLQYPQQHPQALTGSSSSNSSSNYGVANCASANSSSALMSSISVARASSSRQTTNSPFGALLNAAAQAACASPASSSASVLRYAESPVAHYLERDNGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEEEDEEEDDKGWANSDVEDHMKMDDHVEDGDDEHEDSRSRASHKATTKKSRKAKVSGRKHKRINKHQPDDEDDFMSVGSSCAESEHQLEQQHQTQQTHVPQVASPTPGQLSTAPSTSSGAAAAAVGASCSTNSNKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGATRPFAAVAPIPLVKVEKEEPMDDYDTVRDEMQAMEQKHNMENASGSSNSSNSGHGTTSVIRMASTSSTTTTTNVANDDLTQPPPMKVEVEPTVLLPQRFSAPAQHRGPKKLVIKPKATVTAAAASTATTKKTDNNAASSSNCAETLSISSKASPEPLQIKSENVEHAPTSGSILEKHLTNSFAAQQARKHSAVNDDDARVLLEFANSKQQLPPGNSNQTTFVVNAASFASAGSVFASGSSNVQKSTKPGDEYILPDNNLEVDEIVISSSSSYASDSQHEQLQQQQQSQQSQQQQQQPPAQQALQQSQQPSSFTDFNFLYHQHGTTTAAATSTAAATSTATTFAPFGMQQQQQVLQHPQHGSSEATNAATLASSSSNSSALDQDCSMNATFRVSKQQSTMGPWYQPQPQQQPQASTSHGSSVEQSSNFIAALAAVECCSVAAVDSDVSEAKYLDLDTCKREQLSNSSSHLPSASASTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDLSQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQPEREQKRFDFNAVASEYTNPGQLDTSPGSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVNTTLVDPQEQESQGQQQQRQLLQAAGHSNGDIVHEDSKDGIIKIKQEHCHDKQDASEQLLAHSELPDVKDSGLLNGSDENGRDADMKPPAGVTDLDEKPAIPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYICDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKILVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516419;
90% Identity: iTF_00544682;
80% Identity: -