Basic Information

Insect: Drosophila micromelanica
Gene Symbol: -
Assembly: GCA_004143905.1
Location: SCDX01000071.1:60854-67802[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.041 2.9 8.3 0.2 1 23 1310 1333 1310 1333 0.94

2 14 6.6 4.6e+02 1.4 0.2 1 23 1495 1517 1495 1517 0.91

3 14 0.00015 0.01 16.0 2.7 2 23 1520 1541 1520 1541 0.97

4 14 5.7e-05 0.004 17.3 0.2 3 23 1549 1569 1547 1569 0.98

5 14 1.5 1.1e+02 3.4 1.4 2 13 1576 1587 1575 1591 0.84

6 14 0.06 4.2 7.8 2.8 8 23 1600 1615 1599 1615 0.96

7 14 4.5 3.1e+02 1.9 0.4 5 23 1628 1646 1626 1646 0.96

8 14 1.1 78 3.8 5.4 3 23 1653 1674 1651 1674 0.93

9 14 0.12 8.3 6.9 0.2 2 23 1685 1705 1684 1705 0.96

10 14 4.5e-05 0.0032 17.6 0.4 1 19 1711 1729 1711 1733 0.95

11 14 1.3e-05 0.00091 19.3 0.5 1 23 1741 1763 1741 1763 0.98

12 14 8.5e-05 0.006 16.8 7.6 1 23 1769 1791 1769 1792 0.96

13 14 0.00017 0.012 15.9 5.9 1 23 1797 1819 1797 1819 0.98

14 14 0.023 1.6 9.1 8.2 1 23 1825 1847 1825 1848 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.041	2.9	8.3	0.2	1	23	1310	1333	1310	1333	0.94
2	14	6.6	4.6e+02	1.4	0.2	1	23	1495	1517	1495	1517	0.91
3	14	0.00015	0.01	16.0	2.7	2	23	1520	1541	1520	1541	0.97
4	14	5.7e-05	0.004	17.3	0.2	3	23	1549	1569	1547	1569	0.98
5	14	1.5	1.1e+02	3.4	1.4	2	13	1576	1587	1575	1591	0.84
6	14	0.06	4.2	7.8	2.8	8	23	1600	1615	1599	1615	0.96
7	14	4.5	3.1e+02	1.9	0.4	5	23	1628	1646	1626	1646	0.96
8	14	1.1	78	3.8	5.4	3	23	1653	1674	1651	1674	0.93
9	14	0.12	8.3	6.9	0.2	2	23	1685	1705	1684	1705	0.96
10	14	4.5e-05	0.0032	17.6	0.4	1	19	1711	1729	1711	1733	0.95
11	14	1.3e-05	0.00091	19.3	0.5	1	23	1741	1763	1741	1763	0.98
12	14	8.5e-05	0.006	16.8	7.6	1	23	1769	1791	1769	1792	0.96
13	14	0.00017	0.012	15.9	5.9	1	23	1797	1819	1797	1819	0.98
14	14	0.023	1.6	9.1	8.2	1	23	1825	1847	1825	1848	0.95

Sequence Information

Coding Sequence: ATGGGGGACAGTGTACAGTGCCCCGTGTGCACCCTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTGATCAAGGCGCTGGTGCAAATGACCATCGTTGGCAGCAATGGAATGGACAGCGCCCTGGCGGCCGCTGTGCTCTCTGGCAACAGCGCTGCAACATCAGATGCGGGTGCCGCCGCCTCATCTACATCGTCGTCATCTACGTCCGCTACTGTTGATGTGAAGCCAGTTGTGCCAGCagcacctccacctccaccaccagctccaactccaacAACATCCAAATCAGCAGCATCCAAAACTGCGTTGCtgcacagcggcagcagcagcagcagcagcagctgcaccaacAAATTGAGCAATCCACCGATTAAGGCAGTTAAAAGCGCGCCACCCACGACTGAGGCGCCAGCCACCACATCCAATACACCCACCATAAGCAGCGTGGCCGCCGTTTACTCCGACTATCGCTATGAACAGcagccccagcagcagcagcagcatcacggCTTTGCACGTGGTGCCACCACGCTGGTCATACCACAGACAccacagcagcaccagcaccagttCCTGGCCAGCCAACAGCAGTCTGCCCACTTTGCCCACcattcgcagcagcagccggccaTGAAGTACACTTATGCAACAGCGCtgcctccgccgccgccgccgctgcagCTCTTTGCACAGCATGCGACGGCAACGCAGTCGCATCAGAAGCCACCACCCGCCTATGGCGCCGCCATCAGTCAAATTAGATCTCAGcacaaccaaaacaaacatcagcaacaacaacaacaacagcagcagcagcagcagcagcagcagcaacagcagcagcaacaacacataAACGTACAACAAAACATTAACCTAGCACCACCGAGTgacaaacacaacaaagtACATACGGAGATCTTTCTAAATCCACCGCCTCCACCACCGCCACAGCTCACGATTCCGTCAACGTCAACCGCATCAAGACTGCAacatccacaacaacaacaacaatcacagcaATCACTTGctgcgagcagcagcaacagcagctatgTGGTAGCCACCTACGCCAGCTCCTGGTCGTCTCTTATGTCATCAAGCTCAGCCGGACGCGCCAGCAGCAGTCGCCAAACGACCAACTCGCCCTTTGGTGCCCTGCTAAATGCTGCAGCGCAAGCTGCCTGCGCCTCGCCCGCCTCCTCCGGCGCTGCGTCTGTGCTGCGCTATGCCGAGTCGCCAGTGGCGCACTATCTGGAGCGGGAAAACGGCGACTTTATAGTCCAGGAGACGCCCAAGCACATTGTCGAGTGCGTGGAGAAGGACGACGGGGAGTTCTCTGTGATTGAACGCATCTATCAGTCGCCACCCAGCGTTCTGCATATACACGACGACGATGAGGACGacgaagaggaggaggaggacgaggaggaggCAGATAAAGGCTGGGCAAACAGCGAGGATGAGAATCACGTTAAGCTGGCACACGAGCATGTCGAGGATGGCGACGATGAGCACGAGGATAGTCGCAGCAGAGTTGGACCCAAGACCACATTGAAAAAGTCACGGAAGTCAAAACCAAATGGCAGGAAGCATAAACGTGCTGCCAAACATCAGCCGGAGGATGAGGACGACTTTATGAGCATAGGCAGCAGCTGTGCCGAGAGCGATCATCAGCTGGACGAGCAACAGCCGGCGCAAACGCATGCGGCACCGGTTGCGTCCACTTCGCCCGCACAACTGTGCACAGCGCCTTCGACAAGcggtggagcagctgctgcagctgtggctgctgtCGGATCAAGCGGTGCCAGCGCGACTACCAGCGGCTCCATCAAGTCCAAGAAGAATCGTGTGACGGTGCTCAGCGATGTGCCGCTAAACATGAACGAGTATCTGGATCTGGTGGGGAACATTGTGGCCTCCAGTCGCATTGGTGCGGTCCGTCCGTTTGCCGCCGTGGCGCCTATACCGTTGGTTAAGGTGGAAAAGGAGGAGCCGCTGGACGACTACGACACTGTGCCGAATGCAGAGATGCAGTCATTGGAGCACAAACCCAGCGGGGAACAtgccagtggcagcagcaatagcagcagcagtggacACGCCACCACCAGCGTCATTCGCATGGCCAGcaccagcgccagcagcagcgcgaaCGTGGCCACCGACGATCTCACACAGCCGCCGCCCATgaaggtggaggtggaggcaACGGTGCTGATGCCGCAGCGCTTCTCAACGCCGGCGCAGCAACGGGGCCCCAAGAAATTAGTCATCAAACCAAAGGCCACAGCAACGTCGACGGCAACGTCAatagcaacgacaacaacgacaaacaagactgacaacaacagcagcagcggcaactgcggGGAAAGCTCCACCAGCATATCAAAGGTGTCCACGGAACCGGTGCAGATCAAGAGCGAGAACGTGGAGACGACTACAAcgagtggcagcagcagcagcattctGGAGAAGCATCTGACAACCAGCTATGCGGCACAGCAGGCGCGCAAACACTCGGCGGTCAATGATGACGATGCCCGCGTGCTGCTGGAGTTTGCTAATTCGAAGCAGCAGCCGTTGGCTGGCAACAGCAATCAGACCACGTTTGTGGTGAATGCGGCCAGTTTTGCGTCGGCGGGCTCCGTGttcgccagcagcagcggcggcgctCAGAAGTCGACCAAGCCGGGCGAAGAGTATTTTCTACCTGATGATAACAATCTGGAGGTGGATGAAATTGTGATATCGTCCTCGTCTTCCTATGCCTCCAactcgcagcagcaacagcactcGCAGTCggagtcgcagcagcagcaacagcagccagcgcAGCAGGTCTTGCAGCAGGCCCAGCAGCCGTCCGCCTTTACGGACTTCAATTTCCTGTACCATCCCAACGCGACAACAGCGacatcagcaacaacggcggcagcaacaaccactGGCAACTTTACTCCGTTTGgcttacagcagcagcaacagcagcagcagcagctgcaacatcCCCACCATGGCTCTAGCGAAGCCACCAATGCCGCCACGCTGGCATCCTCCTCCAGCAACTCATCCGCATTGGACCAGGATTGCTCGATGAATGCCACGTTTCGCGTAGCCAAGCAACAAACAACGCTGAGCTCCTGGTATCAggcacatcagcagcagcagccgcaggcaACCACCTCACACGGCTCCGGTGTGGAGCAGTCGAGCAATTTCATCGCCGCACTCGCAGCCGTCGATTGCTGCAGCGTGGCGGGTGTTGACAGCGATGCCAAGTACTTGGATCTGGATGCCTGCAAGCGGGAACAGctcagcaatagcagcagtcatTTGCCCTCGGCCTGTGCGTCCACGTCCACAACATCCTCATCGTTTGCAGCTGCGCCCACGGAGAGCAGTCTGGTTGGTGGCCTGGGTCTGAACATACGCACCGACGAGAAGATGCCCGCCAAGGGTGAGATCTCCGAGCAGGAGAGCAACTGCGACATCGAGAACTCCTGGAGTCAATCGATGTACGGCGACATATCACAGCGTTACTTTAGAGGCCAGTTCACGGATGGCTACAATCAGCAGCTGGCCGATTGGCGGCACGACTATTATCCGGCGCAGGATCTtagtggccagcagcagcatcagcagtcACAGCGTGAACAAAAGCGCTTTGATTTCAACTCGGTCGCCTCGGAATACGCGCAGCCGGGCGATTTGGACGCCACCTCGAGCTCAACTAGAAACAATCATTTGCTGGATGTACAGCCCACCACTTCCACGTCGTCGTCGGCTTTGCTGGCTGGTCCACCGATAGCCTCGACATCCCGTGCGGCCGCCGAAGCGGAGGCTGTGGCCGCGGCGCTGGCACAACGGAAGCCGCCGCGGCGCAAGATCTACAAGTGTCCGCACTGTGTGGCCATATTTGAAAAGCTCAAGGAGCGCAATGCGCACATGATCGGCGAGCATAACTATGTACGTCAAAATCGACGTCTCATCTGCACCCTGGCATCTCATCTGCCACAGTCGCAGGCTCAACAggagccgcagcaacaacaacaacagcagcatctgtTGCTCCAGGCGGGGCACAGCAATGATGATGTCGTGCACGAGGACTCCAAGGATGGCATTGTGAAGATCAAGCAGGAGCACTGTCAGGATAAACAGGATTCAACGGAGCAGCTGCTTGGCCAAATGGAGCTGCCCGACGTAAAGGACTCGGGCCTGCTCGATGCCAGCGGTGAGAACGGTCGCGACACGGACATGAAGCCACCAACAGGGGTCACCGAGCTTGACGAGAAGCCCGCCATAGCGCCGTTGGCCATGACCACGCCCGCTGCCAAACTGGCCGCCCTCTATCGCATGCTAATTGCCTACAACGAGTCGAAACTGGGCCAGGAGCGCAACAATCTCAGCGAGCTGGAGCAGAAGGCCATGGAGAAATCCATATTCCTTTGCTATGTCTGCCGCACCGATTTCCCCTCCGTGAAGCTGTACGATGCACATCTCACTGAGCATCCCGCCGAGTGTTTCACCTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTCTCGCTGCACCTGAAACGACATCTAGGCTGGAAGGAGTTCGGCTGCTACGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCACTCGTGGAGCACATGCGCATGCACACTGGCCAGACTCCGCTCAAATGCAAGATATGCGGTAAGCTGTACAAAAATACTCATTATATTTGCTTGAAATGGAATTCTTTATTGAGCAAGAAGTTCAAGCGTTATTCCAACTTGACGCAGCATCGCAAGCGACACACCAAGATGATGGTGCGTAAAAAGGAGTACGTGTGCCACTGCGGCGAGGTTCTGCCCTCGAAGGCGCGCTTCCTGTGGCACAAAGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTATTGCTGCGATCGTTTTGTGCATGCGAACTCGCTGCGCCGGCATATTAGACTGGCCCATTCGGACAAGTTCGACTATGCCGAGCCCATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATCAAGGCGCACATGGCCACCCACTCGACGGATCCGCAATACGACTGCGCCATTTGCAACAAGAGCTTCTCCACCAAGTGGAATCTCAAAATACATTCGTGGGTGCACGCGAATCGCACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTACGCGAGCTGGACTTCAAGAACCACATGAATGCGCACAAACAAATCAAGCCCTACACCTGTGAGTACTGCGGCTGCAAGTTCATACGCAAGTACAACTATATGCGGCACCGGCGAGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAGTCCTTCCATCGCCACTACTATCTGATCGAGCACAGGCGCATCCATACCGGCGAACGGCCATTCCACTGCACCATCTGTGGCAAGAGCTCGACCACGAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGCGATCCCTTTACTGTGGAGGTTTAA
Protein Sequence: MGDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGSNGMDSALAAAVLSGNSAATSDAGAAASSTSSSSTSATVDVKPVVPAAPPPPPPAPTPTTSKSAASKTALLHSGSSSSSSSCTNKLSNPPIKAVKSAPPTTEAPATTSNTPTISSVAAVYSDYRYEQQPQQQQQHHGFARGATTLVIPQTPQQHQHQFLASQQQSAHFAHHSQQQPAMKYTYATALPPPPPPLQLFAQHATATQSHQKPPPAYGAAISQIRSQHNQNKHQQQQQQQQQQQQQQQQQQQQQHINVQQNINLAPPSDKHNKVHTEIFLNPPPPPPPQLTIPSTSTASRLQHPQQQQQSQQSLAASSSNSSYVVATYASSWSSLMSSSSAGRASSSRQTTNSPFGALLNAAAQAACASPASSGAASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDEDDEEEEEDEEEADKGWANSEDENHVKLAHEHVEDGDDEHEDSRSRVGPKTTLKKSRKSKPNGRKHKRAAKHQPEDEDDFMSIGSSCAESDHQLDEQQPAQTHAAPVASTSPAQLCTAPSTSGGAAAAAVAAVGSSGASATTSGSIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAVRPFAAVAPIPLVKVEKEEPLDDYDTVPNAEMQSLEHKPSGEHASGSSNSSSSGHATTSVIRMASTSASSSANVATDDLTQPPPMKVEVEATVLMPQRFSTPAQQRGPKKLVIKPKATATSTATSIATTTTTNKTDNNSSSGNCGESSTSISKVSTEPVQIKSENVETTTTSGSSSSILEKHLTTSYAAQQARKHSAVNDDDARVLLEFANSKQQPLAGNSNQTTFVVNAASFASAGSVFASSSGGAQKSTKPGEEYFLPDDNNLEVDEIVISSSSSYASNSQQQQHSQSESQQQQQQPAQQVLQQAQQPSAFTDFNFLYHPNATTATSATTAAATTTGNFTPFGLQQQQQQQQQLQHPHHGSSEATNAATLASSSSNSSALDQDCSMNATFRVAKQQTTLSSWYQAHQQQQPQATTSHGSGVEQSSNFIAALAAVDCCSVAGVDSDAKYLDLDACKREQLSNSSSHLPSACASTSTTSSSFAAAPTESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRGQFTDGYNQQLADWRHDYYPAQDLSGQQQHQQSQREQKRFDFNSVASEYAQPGDLDATSSSTRNNHLLDVQPTTSTSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTLASHLPQSQAQQEPQQQQQQQHLLLQAGHSNDDVVHEDSKDGIVKIKQEHCQDKQDSTEQLLGQMELPDVKDSGLLDASGENGRDTDMKPPTGVTELDEKPAIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKLYKNTHYICLKWNSLLSKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516419;
90% Identity: -
80% Identity: -