Basic Information

Insect: Drosophila leonis
Gene Symbol: -
Assembly: GCA_035045365.1
Location: JAWNPC010000338.1:139758-145678[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.051 3.9 8.3 0.2 1 23 1331 1354 1331 1354 0.94

2 13 8.3 6.3e+02 1.4 0.2 1 23 1521 1543 1521 1543 0.91

3 13 0.00019 0.014 16.0 2.7 2 23 1546 1567 1546 1567 0.97

4 13 4e-05 0.003 18.1 0.2 3 23 1575 1595 1573 1595 0.98

5 13 6e-07 4.5e-05 23.9 4.1 2 23 1602 1623 1601 1623 0.97

6 13 5.7 4.2e+02 1.9 0.4 5 23 1636 1654 1634 1654 0.96

7 13 1.4 1.1e+02 3.8 5.4 3 23 1661 1682 1659 1682 0.93

8 13 0.15 11 6.9 0.2 2 23 1693 1713 1692 1713 0.96

9 13 5.7e-05 0.0043 17.6 0.4 1 19 1719 1737 1719 1741 0.95

10 13 1.6e-05 0.0012 19.3 0.5 1 23 1749 1771 1749 1771 0.98

11 13 0.00011 0.0081 16.8 7.6 1 23 1777 1799 1777 1800 0.96

12 13 0.00021 0.016 15.9 5.9 1 23 1805 1827 1805 1827 0.98

13 13 0.03 2.2 9.1 8.2 1 23 1833 1855 1833 1856 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.051	3.9	8.3	0.2	1	23	1331	1354	1331	1354	0.94
2	13	8.3	6.3e+02	1.4	0.2	1	23	1521	1543	1521	1543	0.91
3	13	0.00019	0.014	16.0	2.7	2	23	1546	1567	1546	1567	0.97
4	13	4e-05	0.003	18.1	0.2	3	23	1575	1595	1573	1595	0.98
5	13	6e-07	4.5e-05	23.9	4.1	2	23	1602	1623	1601	1623	0.97
6	13	5.7	4.2e+02	1.9	0.4	5	23	1636	1654	1634	1654	0.96
7	13	1.4	1.1e+02	3.8	5.4	3	23	1661	1682	1659	1682	0.93
8	13	0.15	11	6.9	0.2	2	23	1693	1713	1692	1713	0.96
9	13	5.7e-05	0.0043	17.6	0.4	1	19	1719	1737	1719	1741	0.95
10	13	1.6e-05	0.0012	19.3	0.5	1	23	1749	1771	1749	1771	0.98
11	13	0.00011	0.0081	16.8	7.6	1	23	1777	1799	1777	1800	0.96
12	13	0.00021	0.016	15.9	5.9	1	23	1805	1827	1805	1827	0.98
13	13	0.03	2.2	9.1	8.2	1	23	1833	1855	1833	1856	0.95

Sequence Information

Coding Sequence: ATGGTGGACAGCGTGCAGTGCCCCGTGTGCACCCTGTATTTGCATGCGGGCATGAATCTCTCCGATCATTTGGAGACACATCCCAAGGAGCAGGTCATCAAAGCACTGGTGCAAATGACCATTGTCAGCAACAGTGGCATGGGCAGCGCCCTGGCCGCAGCTTTGCTCTCTGGTGATGCCGCCACGAGCGCCACGAATGCGCTTGATGTCAAACCAGTTGTACCAGCATCTTCACCAACAcctccaccaccaccaccagcaccaacaacaacaacaacagcaactgcagcggcagcaactaaatcaacaacACCCAAAGCTGCGttgcccagcagcaacagcaacagcaacagcagcagcagcaccagcagctgcaacaacaacaacaacaaattgagcaATCCACCGATAAAGGCAGTAAAAAGCGCGCCACCCACGACTGAGGCGCCAGCAGCCAACACATCAAACACACCCACCACAAACAGCGTGACCGCCATCTATTCCGACTACCGCTATGACCAGCAGtcccaacagccaacagcaacagcaacggtgCATGGCTTTGCACGTGGTGCCACCACGCTGGTCATACCACAAGCAccacaccaacagcagcagcagcagcagcagcatcagtatCTGGCCACACAGCAGCAGGCTGCTCATTTTGCCCAccttcagcagcaacagcaacagccggcCATGAAGTACACCTATGCAGCAGCGctgccaccaccgccaccactgCAGCTCTTTGCGCAGCAGGCGACATCAACGCAATCACATCAGAAGCCACCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCacaaccaaaacaaacagcaacagcaacaacaacagcagcagcaacaacaacagccacaacaacaacagcagccacaacaacacaTAAGCTTGCAACATAACATTAACCTTGCACCACCGAGTGGCAAACATAGTAAGCTTCATGCAGATATCTTCTTGAatccaccgccaccaccaccgccacagCTCACAATTCCGTCAACATTGTCAACTGCCTCACTAAGACTGCAAtatccgcagcagcagcagcagcagcaatcccTTGCTgtcagcagtagcagcagtagcagcagcagcaccagcagcagcaataataataataataattatgcagTAGCTAACTGCGCCGCAGCTAGCTCCTCGTCTGCCCTGATGCTTGGACgcgccagcagcagtcgcCAGACAACCAATTCACCATTTGGTGCACTGTTGAATGCTGCAGCGCAAGCTGCCTGCGCCTCACCCGCCTCGTCCAGTGCGTCTGTGCTGCGCTATGCCGAATCGCCAGTGGCGCACTATTTGGAGCGCGAGAATGGCGACTTCATAGTCCAGGAGACTCCCAAGCACATTGTCGAGTGCGTTGAGAAGGAGGACGGCGAGTTCTCAGTGATTGAACGCATCTATCAGTCGCCGCCCAGCGTGCTGCACATACACGACgatgacgaggacgacgagGAGGAagacgaggaggaggatgacAAGGGATGGGCTAACAGCGATGTTGAGGATCACATGAAGCTGGAAGATCATGTGGAGGATGGTGACGATGAGCACGAGGATAGCCGCAGCCGAGCTTCACACAAGGCCACAGCGAAAAAGTCAcgcaaagcaaaggcaaatggCAGAAAGCAGCACAAACGCATCAGCAAACCGCAGCCGGACGAAGAGGATGACTTCATGAGCATAGGCAGCAGCTGTGCTGAAAGCGACCATCAGTtggagcaacagcatcagACGCAGCCATCGCATGTGCTGCCACAGATGGCGTCGCCCACGCCAGGTCCACTGTCCACGGCGCCATCAACGAGCAGTGGAGCAGCCGCGGCtgcagccgccgccgtcgcctgcagcagcaacgcaaACTCAAAGTCCAAAAAGAATCGTGTCACAGTGCTCAGCGATGTTCCGCTCAACATGAACGAGTATTTGGATCTGGTGGGCAACATTGTGGCCTCTAGTCGCATTGGCGCTACTCGTCCGTTTGCTGCTATGGCGCCCATGCCGTTGGTCAAGGTGGAGAAGGAGGAGCCCATGGATGACTACGATACGGTTGGTGATGAGATGGAGCAAAAGCATAGCATGGAGAATGCCAGTGGCAGCAgtaatagcagcaacagcggccaTGGCACCACCAGTGTCATACGAATggccagcaccaccaccacccccacaaccacaaccacaaatGTTGCCAACGACGATCTCACACAGCCGCCGCCCATGAAAGTGGAGGTGGAGCCAACGGTGCTGCTGCCGCAACGCTTCTCAGCGCCCGCGCAGCATCGTGGACCCAAGAAGTTAGTCATCAAACCAAAGGCCACAGCGACGGCGTCAGCAACATCGACTAAAAAGACTGATAACAatgctgccagcagcagcagcaactgtgccGCAACACTCAGCATATCATCGAAAGCAGCCGCAGAGCTGCAGCCGTTGCAGATCAAGAGCGAGAGTGGGGAGCATGTGGCCACAAGCGGCAGCATATTGGAGAAGCATCTGACCAACAGCTATGCCGCACAGCAACAGGCACGCAAACACTCTGCCGTCAACGATGACGATGCACGCGTGCTGCTTGAGTTTGCCAACtccaagcagcagctgccgccagGCAATAGCAATCAGACGACATTTGTGGTGAATGCGGCCAGTTTTGCTTCGGCGGGCTCCGTGTTTGCGAGTGGCAGCAGCGTTCAGAAGCCAACCAAGCCGGGCGATGAGTACATTCTGCCAGATAATAATCTAGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCGACTCGCAGCACgaacagttgcagctgcagcagcagcaacagcagcgggagcaacagcagcagcagcaacagcagccgccagCGCAGCAAAGCGTACAGCCATTGCAGCAGCCGTCCTCCTTTACAGATTTCAATTTTCTGTACCATCAGCATggaacaacaactgcagcagcagcagcagcaacaacgacagcagcagcagcaacaacaacaactgcctcACCTTTTGCACCATTTggcatgcagcagctgcatccaCAACATGGCTCAAGCGAAGCCACCAATGCCGCCACGCTGGCCTCCTCCTCTAGTAACTCATCAGTCCTAGATCAGGATTGCTCCATGAATGCCACCTTCCGAGTTGGCAAACAGCAATCCACAATGGGTGCTGCCTGGTatcagccacagcaacagcaacacccaCAGCCACAGGCAAGCACCTCACACAGCTCCAATGTGGAGCAGTCCAGCAATTTTATTGCCGCTCTGGCCGCTGTTGAGTGCTGCAGCGTGGCGGCCGTGGATAGCGATGTGAGCGAAGCGAAGTACTTGGATCTGGATACCTGTAAGCGGGAGCAgctgagcaacagcagcagccatttgCCCTCGGCCTCTGCATCCACCACATCCTCATCATTTGCGGCCGCCGCCACGGAGAGCAGTTTGGTTGGTGGCCTCGGCCTGAACATACGCACCGATGAGAAAATGCCCGCCAAGGGTGAAATCTCCGAGCAGGAAAGCAACTGTGACATAGAGAACTCCTGGAGTCAATCGaTGTACGGCGACCTCTCGCAGCGCTACTTTCGAAATCAGTTTACGGATGGCTATAATCAGCAGCTGGCCGATTGGCGTCACGATTACTATCCGGCGCAGGATCTcagtggccagcagcagccagagcgTGAGCAAAAGCGCTTTGATTTTAATGCTGTCGCTTCGGAGTATGCGCATCCGGGCCAGCTGGATGCTTCGCCAGGTTCGAGCAGAAACAATCATTTGCTGGATGCACAGCCCACCActtcctcgtcgtcgtcggcggCTTTGTTGGCTGGTCCACCAATAGCCTCGACATCACGTGCTGCGGCCGAAGCGGAGGCTGTGGCCGCAGCTCTGGCGCAACGGAAGCCACCACGTCGCAAGATCTACAAGTGTCCGCACTGCGTGGCCATCTTTGAGAAGCTGAAGGAGCGTAATGCGCACATGATTGGCGAGCACAACTATGTGCGCCAGAATCGACGTCTCATCTGCACCCAGGCCTTGGTCAGTGCCACATTAACCGATCCGCAGGAGCAGCAGGCGCagggacagcagcagcagcaacagcatcaattGCTGCAGGCAGGGGCGGGTCACAGCAATGGCGGCATTATGCATGAGGATTCCAAGGATGGCATCATAAAGATTAAGCAGGAACACTGCCACGATAAACAGGATGCTTCTGAGCAGCTGCTTGGCCATTCAGAGTTGCCCGATGTCAAGGACTCGGGGCTACTCAATGGCACCGATGAGAATGGCCGCGATGCGGACATGAAACCACCAGCGGGCGTCACAGACCTGGACGAGAAGCCGACCATACCTCCGTTGGCCATGACCACACCAGCTGCCAAGCTAGCTGCTCTGTATCGCATGCTCATTGCGTACAATGAGTCCAAGCTGGGCCAGGAGCGCAACAATCTGAGCGAACTTGAGCAAAAGGCCATGGAGAAATCCATATTTCTATGCTACGTCTGTCGCACTGATTTCCCCTCCGTCAAGCTGTACGATGCTCATTTGACGGAGCATCCCGCCGAGTGTTTCACCTGCGGCAAGAAATTCTATCGCTGGAAGAACTTTTCGCTGCATCTGAAGCGTCATTTGGGCTGGAAGGAGTTTGGCTGTTACATCTGCGACAAGAAGTTCGTGGTGCGCAGCGCCCTAGTGGAGCACATGCGCATGCACACGGGCCAGACACCGCTCAAGTGCAAGATATGCGGCAAAAAGTTCAAGCGATATTCGAACTTGACACAACATCGAAAGCGTCACACCAAGATCTTGGTGCGCAAGAAGGAGTATGTGTGCCACTGTGGCGAGGTGCTGCCGTCTAAGGCACGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAGTGCTGTCCCTATTGCTGCGATCGTTTCGTGCACGCCAATTCGCTGCGCCGGCACATTCGACTGGCCCATTCGGATAAGTTTGACTATGCCGAGCCCATGGAGTGCCCCATGTGCAAGCAGATCTTTGCCAAGACCTCCATCAAGGCGCATATGGCGACGCACTCGACAGATCCGCAATACGATTGCGCCATATGCAACAAGAGCTTCTCCACCAAATGGAACCTGAAGATACATTCGTGGGTGCACGCGAATCGCACAGCCAAGCCGTTCAAGTGCGAATACTGCCCCAAGGCTTTCGTACGCGAGCTGGACTTCAAGAATCACATGAATGCGCACAAGCAGATCAAGCCGTACACTTGCGAGTATTGTGGCTGCAAGTTCATACGCAAATACAACTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAGTCTTTCCATCGTCATTATTATCTGATTGAGCATCGGCGCATCCATACCGGCGAGCGTCCGTTCCATTGTACCATCTGTGGCAAGAGCTCGACGACAAAGACCAATCATAATAAGCATCTGAAGATACATCATTCACGGGATCCATTCACCGTGGAggtttaa
Protein Sequence: MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVSNSGMGSALAAALLSGDAATSATNALDVKPVVPASSPTPPPPPPAPTTTTTATAAAATKSTTPKAALPSSNSNSNSSSSTSSCNNNNNKLSNPPIKAVKSAPPTTEAPAANTSNTPTTNSVTAIYSDYRYDQQSQQPTATATVHGFARGATTLVIPQAPHQQQQQQQQHQYLATQQQAAHFAHLQQQQQQPAMKYTYAAALPPPPPLQLFAQQATSTQSHQKPPPAYGAAISQIRSQHNQNKQQQQQQQQQQQQQPQQQQQPQQHISLQHNINLAPPSGKHSKLHADIFLNPPPPPPPQLTIPSTLSTASLRLQYPQQQQQQQSLAVSSSSSSSSSTSSSNNNNNNYAVANCAAASSSSALMLGRASSSRQTTNSPFGALLNAAAQAACASPASSSASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEEEDEEEDDKGWANSDVEDHMKLEDHVEDGDDEHEDSRSRASHKATAKKSRKAKANGRKQHKRISKPQPDEEDDFMSIGSSCAESDHQLEQQHQTQPSHVLPQMASPTPGPLSTAPSTSSGAAAAAAAAVACSSNANSKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGATRPFAAMAPMPLVKVEKEEPMDDYDTVGDEMEQKHSMENASGSSNSSNSGHGTTSVIRMASTTTTPTTTTTNVANDDLTQPPPMKVEVEPTVLLPQRFSAPAQHRGPKKLVIKPKATATASATSTKKTDNNAASSSSNCAATLSISSKAAAELQPLQIKSESGEHVATSGSILEKHLTNSYAAQQQARKHSAVNDDDARVLLEFANSKQQLPPGNSNQTTFVVNAASFASAGSVFASGSSVQKPTKPGDEYILPDNNLEVDEIVISSSSSYASDSQHEQLQLQQQQQQREQQQQQQQQPPAQQSVQPLQQPSSFTDFNFLYHQHGTTTAAAAAATTTAAAATTTTASPFAPFGMQQLHPQHGSSEATNAATLASSSSNSSVLDQDCSMNATFRVGKQQSTMGAAWYQPQQQQHPQPQASTSHSSNVEQSSNFIAALAAVECCSVAAVDSDVSEAKYLDLDTCKREQLSNSSSHLPSASASTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDLSQRYFRNQFTDGYNQQLADWRHDYYPAQDLSGQQQPEREQKRFDFNAVASEYAHPGQLDASPGSSRNNHLLDAQPTTSSSSSAALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSATLTDPQEQQAQGQQQQQQHQLLQAGAGHSNGGIMHEDSKDGIIKIKQEHCHDKQDASEQLLGHSELPDVKDSGLLNGTDENGRDADMKPPAGVTDLDEKPTIPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYICDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKILVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516419;
90% Identity: iTF_00544682;
80% Identity: -