Basic Information

Gene Symbol
-
Assembly
GCA_037075265.1
Location
JBAMCI010000035.1:10910431-10916365[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.051 3.7 8.3 0.2 1 23 1339 1362 1339 1362 0.94
2 13 8.3 5.9e+02 1.4 0.2 1 23 1527 1549 1527 1549 0.91
3 13 0.00018 0.013 16.0 2.7 2 23 1552 1573 1552 1573 0.97
4 13 4e-05 0.0029 18.1 0.2 3 23 1581 1601 1579 1601 0.98
5 13 5.9e-07 4.2e-05 23.9 4.1 2 23 1608 1629 1607 1629 0.97
6 13 5.6 4e+02 1.9 0.4 5 23 1642 1660 1640 1660 0.96
7 13 1.4 1e+02 3.8 5.4 3 23 1667 1688 1665 1688 0.93
8 13 0.15 11 6.9 0.2 2 23 1699 1719 1698 1719 0.96
9 13 5.7e-05 0.0041 17.6 0.4 1 19 1725 1743 1725 1747 0.95
10 13 1.6e-05 0.0012 19.3 0.5 1 23 1755 1777 1755 1777 0.98
11 13 0.00011 0.0076 16.8 7.6 1 23 1783 1805 1783 1806 0.96
12 13 0.00021 0.015 15.9 5.9 1 23 1811 1833 1811 1833 0.98
13 13 0.029 2.1 9.1 8.2 1 23 1839 1861 1839 1862 0.95

Sequence Information

Coding Sequence
ATGGTGGACAGTGTGCAGTGCCCCGTGTGCACCTTGTATCTGCACGCGGGAATGAATCTCTCCGATCATTTGGAGACACATCCCAAGGAACAGGTCATCAAGGCACTGGTGCAAATGACTATTGTTAGCAACAATGGCATGGGCAGCGCCCTGGCAGCAGCTTTGCTCTCTGGTGATGCCGCCAGCAGCTCCACCTCATTGTCATCCACGAATGCGGTTGATGTCAAACCAGTTGTACCAGCATCCTCACCACCAcctccaccaccaccaccaacaacaccaacagtagcagcagcagcagctgctgctgcaacgggAGCAACTAAATCAACAACATCCAAAGCTGCGttgcccagcagcaacaacagcagcagcagcagtagcagcagcaacagcaatagcaacagcagctgcggcaacaacaacaataaattgaGCAATCCACCGATAAAGGCAGTAAAAAGCGCGCCACCCACGACTGAGGCGCCAGCCAACACATCAAATACACCCACCACAAACAGCGTGACCGCCATCTATTCCGACTATCGCTATGACCAGCAGCCCCAGCAGGTaacgccaacagcaacaacaactgcggTGCATGGCTTTGCACGTGGTGCCACCACTACGCTGGTAATACCACAAGCACCACACCAGCACCAGTATCTGGCCTCACAGCAGCAGGCTGCCCATTTTGCCCACCttcagcagcatcagcatcagcaacagccgGCCATGAAGTACACCTATGCAGCAGCGctgccaccaccgccaccactgCAGCTCTTTGCGCAGCAGGCGACATCAACGCAATCACATCAGAAGCCACCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAGCACAACCAAAACAAACagaaccaacaacaacaacaacagcagcaacagcaacaacagcaacaacagcaacagcaacaacaacagccacaacaacacatAACCTTGCAACATAACATTAACCTTGCACCACCGAGTGGCAAACATAGTAAACTTCACACGGATATCTTCTTGAAtccaccgccaccaccaccgccacagCTCACAATTCCGTCAACGTTGTCGACTGCCTCATTGAGACTGCAATatccgcaacagcagcagcaatcccTTGCAgccagcagtagcagcagcagcagcagcaacaattatGCAGTAGCTAACTGCGCCTCTGCCAGCTCGTCGTCTGCACTGATGTCATCCATCTCCGTCGGACGCGCCAGCAGCAGTCGCCAGACAACCAACTCTCCCTTTGGTGCGCTGCTTAATGCTGCAGCGCAAGCTGCCTGCGCCTCACCCGCCTCGTCCAATGCGTCTGTGCTGCGTTACGCAGAATCGCCAGTGGCTCACTATTTGGAGCGGGAGAACGGCGACTTCATAGTCCAGGAAACTCCCAAGCACATTGTCGAATGCGTTGAGAAGGAAGACGGCGAGTTCTCAGTGATTGAACGCATCTATCAGTCACCGCCCAGCGTACTGCACATACACGACGATGATGAAGACGACGAAGAGGAAGACGAGGAGGAGGACGACAAGGGTTGGACTAACAGCGATGTTGAGGATCACATGAAGATGGAAGATCATGTGGAGGATGGTGACGATGAGCATGAGGATAGCCGCAGCAGAGCTTCACACAAAGCTACAACGAAAAAGTCAcgcaaagcaaaagcaagtGGTAGGAAGCACAAACGCATCAACAAACATCAaccggatgatgaggatgacTTTATGAGCATAGGGAGCAGCTGCGCTGAAAGCGACCATCAGTTAGAGCTGCCACATCAGATGCAGCAATCGCATGTGCCACAGGCTGTGTCGCCCACGCCAGGTCAACTTTCCACGGCGCCCTCAACGAGCAGtgcggctgccgctgcggcAGCCGCCGTCTCCTGCAGTACCAGCTCGAACAAGTCCAAAAAGAATCGTGTAACAGTGCTCAGCGATGTTCCGCTCAACATGAACGAGTATTTGGATCTAGTGGGCAACATTGTAGCCTCTAGTCGCATTGGCGCTACTCGTCCGTTTGCTGCTGTGGCGCCCATACCATTGGTCAAGGTCGAGAAGGAAGAGCCAATGGATGATTACGATACCGTAAGGGATGAGATGCAGGCAATGGAGCAAAAGCACAGCATGGAGAATGCCAGTggcagcagtaacagcagcaacagtggcCATGGCACCACCAGTGTCATACGAATggccaccaccagcagcagcaccaccaccacaaccaccACAAATGTTGCCAACGACGATCTCACACAGCCGCCGCCCATGAAAGTGGAGGTGGAGCCAACGGTGCTGCTACCGCAACGCTTCTCAGCGCCAGCGCAGCATCGTGGGCCCAAGAAGTTAGTCATCAAACCAAAGGCCTCACTGACGGCGTCAGCAACATCGACGGCGACGACTAAAAAGACTGATAACAACGCTgccagtagcagcagcaactgcgccGAACCACTCAGCATATCATCGAAGGCATCCACAGAGCCGTTGCAGATCAAGAGCGAGAGTGTGGAGAATGTTTCCACGAGTGGCAGCATATTGGAGAAGCATCTAACAAATAGCTACGCCGCACAGCAGGCACGCAAACACTCTGCAGTCAACGACGACGATGCACGCGTGCTCCTTGAGTTTGCCAACtcaaagcagcagccgccgGCGGGCAACAGCAATCAGACTACCTTTGTGGTGAATGCGGCCAGTTTTGCTTCGGCGGGGTCCGTATTTGCGAGTGGTAGTGGCAACGTTCAGAAGTCAACCAAGCCGGGCGATGAGTACATTCTGCCAGATAATAATCTAGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTCCGACTCGCAGCACGAacagatgcagcagcagcagcactcgcagcaatcacagcagcagcaacagcacccgGCAGCGCAGCAAGCCGTGCAGCAATCGCAGCAGCCGTCCTCCTTTACAGATTTCAATTTTCTGTATCATCAGCATggaacaacaactgcagcagcaacaacgacggcggcagcagcaacaactactgCCTCACCCTTTGCACCATTTGGcatgcagcagcatcagcagcagcagcagcagcaggtgctgCAACATCCACAACATGGCTCCAGCGAAGCCACCAATGCCGCTACGCTGGCATCTTCATCCAGTAACTCATCAGTCTTGGATCAGGATTGCTCCATGAATGCGACGTTTCGCGTTGCCAAACAGCAATCCACAATGGGTTCCTGGTATCAGCCACAgtcgcagcaacagccacaggcCAGCACTTCACACAGCTCCAATGTGGAGCAGTCGAGCAATTTTATTGCCGCACTCGCAGCAGTTGAGTGCTGCAGCGTTGCGGCCGTGGACAGCGATGTGAGCGAGGCCAAGTATTTGGATCTGGACACCTGTAAGCGGGAACAGTtgagcaatagcagcagccatTTGCCCTCGGCCTCTGCATCCaccacatcatcatcatttgcGGCCGCCGCCACGGAGAGCAGTTTGGTTGGTGGCTTGGGTCTGAACATACGCACCGATGAGAAAATGCCCGCTAAAGGTGAAATTTCCGAGCAGGAAAGCAACTGTGACATTGAAAACTCCTGGAGCCAATCGATGTACGGCGACCTATCACAGCGTTACTTTAGAAATCAGTTTACGGATGGCTATAATCAGCAGCTGGCCGATTGGCGTCAAGACTACTATCCGGCGCAGGATCTcagtggccagcagcagccagagcgtgaGCAAAAGCGCTTTGATTTCAACGCTGTCGCTGCGGAGTATGCGCATTCGGGCCAGTTGGATACCTCACCAAGTTCGACTAGAAACAATCATTTGTTGGACGCACAGCCCACTActtcctcgtcgtcgtcggcttTGTTGGCTGGTCCACCAATAGCCTCGACATCGCGTGCTGCTGCCGAAGCGGAGGCCGTGGCCGCAGCTCTGGCGCAACGGAAGCCACCGCGTCGCAAAATCTACAAGTGTCCGCACTGTGTGGCCATCTTTGAGAAGTTGAAGGAGCGCAATGCGCATATGATTGGCGAGCACAACTATGTGCGCCAGAATCGCCGTCTCATCTGCACACAGGCATTGGTCAGTAGCACATTGGCAGACCCACAGGAGCAGCAGGCGCagggacaacagcagcaacagcatcaattGCTGCAGGGAGCGGGACACAGCAGTGGTGACATTGTGCATGAGGATTCCAAGGATGGCATTATAAAGATTAAGCAGGAACACTGCCACGATAAACAGGATGCTGCTGACCAGTTATTAGGCCATTCAGAGTTGCCTGATGTCAAGGATTCCGGCCTACTCAATGGCAGCGATGAGAACGGTCGCGATGCGGACATGAAGCCACCAGCCGGCGTCGCAGACTTGGACGAGAAGCCGACAATACCGCCGTTGGCCATGACCACTCCAGCTGCCAAACTTGCTGCTCTGTATCGCATGCTCATTGCATACAATGAGTCTAAGCTGGGCCAGGAGCGCAACAATCTTAGCGAACTTGAGCAAAAGGCCATGGAAAAATCCATATTTCTGTGCTACGTGTGTCGCACTGATTTCCCTTCTGTAAAGCTGTACGATGCTCATTTGACTGAGCATCCCGCCGAGTGTTTCACCTGTGGTAAAAAATTCTATCGCTGGAAGAACTTCTCGCTGCATCTGAAACGCCATTTGGGCTGGAAGGAGTTTGGCTGTTATATCTGCGACAAGAAGTTTGTCGTGCGCAGCGCCCTTGTGGAGCACATGCGCATGCACACGGGTCAGACACCGCTCAAGTGTAAGATATGTGGCAAAAAGTTCAAGCGATATTCGAACTTGACACAACATCGAAAGCGTCACACCAAGATCTTGGTGCGTAAGAAGGAGTACGTGTGCCATTGTGGCGAGGTGTTGCCGTCTAAGGCGCGATTCTTGTGGCACAAGGAAACACACGATTTGAAGCCCAAGTGCTGTCCCTATTGCTGTGATCGTTTTGTGCACGCCAATTCGCTGCGCCGGCACATTCGACTGGCACATTCGGATAAGTTTGACTATGCTGAGCCCATGGAGTGCCCCATGTGCAAGCAGATCTTTGCCAAGACCTCAATCAAGGCGCATATGGCTACGCATTCGACAGATCCGCAATACGATTGCGCCATATGCAACAAGAGCTTCTCCACCAAATGGAATCTCAAGATACATTCGTGGGTGCATGCAAATCGCACGGCCAAACCGTTCAAGTGCGAGTACTGCCCCAAGGCTTTTGTGCGCGAGCTGGACTTCAAGAATCACATGAATGCGCACAAGCAGATCAAGCCATACACTTGCGAGTACTGCGGCTGCAAGTTCATACGCAAATACAACTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAGTCTTTCCATCGGCACTATTATCTGATTGAGCATCGGCGCATCCATACGGGCGAGCGTCCGTTCCATTGCACCATCTGTGGCAAGAGCTCGACGACAAAGACCAATCATAATAAGCATCTGAAGATACATCATTCACGGGATCCATTCACCGTGGAGGTTTAA
Protein Sequence
MVDSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVSNNGMGSALAAALLSGDAASSSTSLSSTNAVDVKPVVPASSPPPPPPPPTTPTVAAAAAAAATGATKSTTSKAALPSSNNSSSSSSSSNSNSNSSCGNNNNKLSNPPIKAVKSAPPTTEAPANTSNTPTTNSVTAIYSDYRYDQQPQQVTPTATTTAVHGFARGATTTLVIPQAPHQHQYLASQQQAAHFAHLQQHQHQQQPAMKYTYAAALPPPPPLQLFAQQATSTQSHQKPPPAYGAAISQIRSQHNQNKQNQQQQQQQQQQQQQQQQQQQQQPQQHITLQHNINLAPPSGKHSKLHTDIFLNPPPPPPPQLTIPSTLSTASLRLQYPQQQQQSLAASSSSSSSSNNYAVANCASASSSSALMSSISVGRASSSRQTTNSPFGALLNAAAQAACASPASSNASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEEEDEEEDDKGWTNSDVEDHMKMEDHVEDGDDEHEDSRSRASHKATTKKSRKAKASGRKHKRINKHQPDDEDDFMSIGSSCAESDHQLELPHQMQQSHVPQAVSPTPGQLSTAPSTSSAAAAAAAAVSCSTSSNKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGATRPFAAVAPIPLVKVEKEEPMDDYDTVRDEMQAMEQKHSMENASGSSNSSNSGHGTTSVIRMATTSSSTTTTTTTNVANDDLTQPPPMKVEVEPTVLLPQRFSAPAQHRGPKKLVIKPKASLTASATSTATTKKTDNNAASSSSNCAEPLSISSKASTEPLQIKSESVENVSTSGSILEKHLTNSYAAQQARKHSAVNDDDARVLLEFANSKQQPPAGNSNQTTFVVNAASFASAGSVFASGSGNVQKSTKPGDEYILPDNNLEVDEIVISSSSSYASDSQHEQMQQQQHSQQSQQQQQHPAAQQAVQQSQQPSSFTDFNFLYHQHGTTTAAATTTAAAATTTASPFAPFGMQQHQQQQQQQVLQHPQHGSSEATNAATLASSSSNSSVLDQDCSMNATFRVAKQQSTMGSWYQPQSQQQPQASTSHSSNVEQSSNFIAALAAVECCSVAAVDSDVSEAKYLDLDTCKREQLSNSSSHLPSASASTTSSSFAAAATESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDLSQRYFRNQFTDGYNQQLADWRQDYYPAQDLSGQQQPEREQKRFDFNAVAAEYAHSGQLDTSPSSTRNNHLLDAQPTTSSSSSALLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCVAIFEKLKERNAHMIGEHNYVRQNRRLICTQALVSSTLADPQEQQAQGQQQQQHQLLQGAGHSSGDIVHEDSKDGIIKIKQEHCHDKQDAADQLLGHSELPDVKDSGLLNGSDENGRDADMKPPAGVADLDEKPTIPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYICDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKILVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00516419;
90% Identity
iTF_00544682;
80% Identity
-