Basic Information

Insect: Drosophila robusta
Gene Symbol: -
Assembly: GCA_004143805.1
Location: SCDV01000386.1:57939-67645[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.043 5.5 8.2 0.2 1 23 1312 1335 1312 1335 0.94

2 13 6.5 8.2e+02 1.4 0.2 1 23 1500 1522 1500 1522 0.91

3 13 0.00015 0.018 16.0 2.7 2 23 1525 1546 1525 1546 0.97

4 13 5.6e-05 0.007 17.3 0.2 3 23 1554 1574 1552 1574 0.98

5 13 4.7e-07 5.8e-05 23.9 4.1 2 23 1581 1602 1580 1602 0.97

6 13 4.4 5.5e+02 1.9 0.4 5 23 1615 1633 1613 1633 0.96

7 13 1.1 1.4e+02 3.8 5.4 3 23 1640 1661 1638 1661 0.93

8 13 0.12 15 6.9 0.2 2 23 1672 1692 1671 1692 0.96

9 13 4.5e-05 0.0056 17.6 0.4 1 19 1698 1716 1698 1720 0.95

10 13 1.3e-05 0.0016 19.4 0.5 1 23 1728 1750 1728 1750 0.98

11 13 8.4e-05 0.01 16.8 7.6 1 23 1756 1778 1756 1779 0.96

12 13 0.00016 0.02 15.9 5.9 1 23 1784 1806 1784 1806 0.98

13 13 0.023 2.9 9.1 8.2 1 23 1812 1834 1812 1835 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.043	5.5	8.2	0.2	1	23	1312	1335	1312	1335	0.94
2	13	6.5	8.2e+02	1.4	0.2	1	23	1500	1522	1500	1522	0.91
3	13	0.00015	0.018	16.0	2.7	2	23	1525	1546	1525	1546	0.97
4	13	5.6e-05	0.007	17.3	0.2	3	23	1554	1574	1552	1574	0.98
5	13	4.7e-07	5.8e-05	23.9	4.1	2	23	1581	1602	1580	1602	0.97
6	13	4.4	5.5e+02	1.9	0.4	5	23	1615	1633	1613	1633	0.96
7	13	1.1	1.4e+02	3.8	5.4	3	23	1640	1661	1638	1661	0.93
8	13	0.12	15	6.9	0.2	2	23	1672	1692	1671	1692	0.96
9	13	4.5e-05	0.0056	17.6	0.4	1	19	1698	1716	1698	1720	0.95
10	13	1.3e-05	0.0016	19.4	0.5	1	23	1728	1750	1728	1750	0.98
11	13	8.4e-05	0.01	16.8	7.6	1	23	1756	1778	1756	1779	0.96
12	13	0.00016	0.02	15.9	5.9	1	23	1784	1806	1784	1806	0.98
13	13	0.023	2.9	9.1	8.2	1	23	1812	1834	1812	1835	0.95

Sequence Information

Coding Sequence: ATGGTGGACAATGTACAGTGCCCCGTGTGCACCCTGTATCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACACATCCCAAGGAGCAGGTCATCAAGGCGCTGGTGCAAATGACCATCGTTGGCAACAATGGCCTGGACAGCGCCCTGGCGGCAGCTGTGCTCTCCGGCAGCgctgcaacaacagaagcGGGTGGCGCCgcctcctcatcctcatcatctGCGCCCGCTACTGCTGATGTGAAGCCAATTGTGCCAGCATCACCtccaactacaacagcaacaacagcaatagcaacaacatccAAATCAGCAGCACCCAAAGCTGCGttgcacaacagcagcagcagtagcagcagcagcagcagcagcagcagtagcagcagctgcaacaacaacaaattgagcaATCCACCGATTAAGGCAGTTAAAAGCGCGCCACCCACGACTGAGGCGCCAGCCACCACATCCAACACACCCACCACAAGCAGCGTGGCCGCCGTCTACTCCGACTATCGCTATGAACAGCagtcccagcagcagcagcagcagcatcatggCTTCGCACGTGGCGCCACCACGCTGGTCATACCACAGgcaccacagcagcagcagcagcagcaccagttCCTGGCCAGCCAACAGCAGTCTGCGCACTTTGCCCAccatccgcagcagcagccggccaTGAAGTACACCTATGCAACGgcgctgccaccgccgccgcctcctctGCAGCTCTTTGCGCAGCAGGCGACGGCAACGCAGTCGCATCAGAAGCCACCACCCGCCTATGGCGCCGCCATCAGTCAAATTCGATCTCAgcacaaccaaaacaaacagcaacagcagcagcagcagcagcaacaacagcaacacataAACGTGCAACAGAACGTTAACCTAGCACCACCGAGTGACAAACACGGCAAAGTCCATGCAGAAATCTTTCTGAATCCACCGCCTCCACCACCGCCACAGCTCACGATTCCGTCAACATCAGCCGCATCAAGactgcaacacacacaacaaccgcaacagcagcagcagcagcaacaacaacaacagcaatctcTTGccgcaggcagcaacaacagcagctacgtGGTAGCCACCTACGCCAGCTCCTGGTCGGCTCTGATGTCATCCAGCTCGGCCGGACGCGCCAGCAGCAGTCGCCAGACGAGCAGCTCGCCCTTTGGTGCTCTGCTGAATGCTGCAGCGCAAGCTGCCTGCGCCTCGCCCTCCTCCTCCAGCGCTGCGTCTGTGCTACGCTATGCCGAGTCGCCCGTGGCGCACTATCTGGAGCGGGAGAACGGCGACTTTATAGTCCAGGAGACGCCCAAGCACATTGTCGAGTGCGTGGAGAAGGACGACGGCGAGTTCTCTGTGATTGAGCGCATCTATCAGTCGCCACCCAGCGTGCTGCACATacacgacgacgatgacgacgacgaagagGAGGaagacgaggaggaggacgataAGGGCTGGGCAAACAGCGATGATGAGGATCACGGGAAGCTGGTGCACGAGCATGTCGAGGATGGCGACGACGAGCACGAGGATAGCCGGAGCAGAGTTGGCCCCAAAACCACAACGAAAAAGTCACGCAAGGCAAAACCAAATGGCAGAAAGCACAAACGTGCCGCCAAGCATCAGCCGGAGGATGAGGACGACTTCATGAGCATAGGCAGCAGCTGTGCCGAGAGCGATCatcagctggaggagcagcagccggcgccggcgcaTGCGCAGCAGTCGCATGCGGCACCAGTTGCGTCCGCGTCGCCGGCTCAACTGTGCACGGCGCCCTCGACGAGCagtggagcagctggagcagctgtgGTCGCTGTTTGCTCGAGCACTGCCAGCTCGACGCAAAGTGGCTCCATCAAGTCCAAGAAGAATCGTGTGACGGTGCTCAGCGACGTGCCGCTGAACATGAACGAGTATCTGGATCTGGTCGGCAACATTGTGGCCTCCAGTCGCATTGGTGCGGCCCGTCCGTTTGCCGCCGTGGCGCCCATACCGCTGGTCAAGGTGGAGAAGGAGGAGCCGCTGGATGACTACGACTCCGTGCGAGAAGCAGAGATGGAGTCAATGGAGCAAAAGCCCAGCCTGGAacatgccagcagcagcagcagcagcaatagttgcagcagcagcggacaCGGCACCACCAGCGTCATTCGCatggccagcaccagcagcagcgcgaacGTGGCCACCGAGGATCTCACACAGCCGCCGCCCATGAAGGTGGAGGTGGAGCCGACGGTGCTGATGCCGCAGCGCTTCTCGACGCCGGCGCAGCAGCGTGGACCCAAGAAATTAGTCATCAAACCAAAGGccacggcgacggcaacggcgacggcgacaacgAAAAAgactgacaacaacagcaccgcCGAAAGCAGCCCCAGCATATCAAAGGCGTCCACGGAACCGGTGCAGATCAAGAGCGAGAACGTGGAGGCGGCCACGAcgagcggcggcagcagcagcagcatcctgGAGAAGCATCTGACCAGCTATGCGGCCCAGCAGGCGCGCAAGCACACGGCCGTCAACGACGATGATGCACGCGTCCTGCTGGAGTTTGCCAACTCgaagcagctgccgccggctGGCAACAGCAATCAGACCACGTTCGTGGTGAACGCGGCCAGCTTTGCGTCGGCGGGCTCCGTgttcgccagcagcagcgggtcCGCCCAGAAGTCGAGCAAGCCGGGCGATGAGTACATTCTGCCTGATGATAGCAAACTGGAGGTGGATGAAATTGTGATATCCTCCTCGTCTTCCTATGCCTccaacatgcagcagcagtcgcagcaccagcaccagcagcagtcgcagcagcagccagcgcagcAGGCCttgcagcaggcgcagcagccgTCCGCCTTCACAGACTTTAATTTCCTGTACCATCCAAgcacgacaacagcagcagcagcagcaacggcaacaaccgCTTCCAACTTTGCGCCATTTGGcatacagcagcaacaacagcagcagcagcagcagctgcaacatccGCACCACGGCTCCAGCGAAGCCACCAATGCCGCCACGCTGGCCTCCTCCTCCAGCAACTCATCCGCATTGGACCAGGATTGCTCGATGAATGCCACGTTCCGCTTGGCCAAGCAACAAACAGCGCTCGGCGCCTGGTATCagtcacagcagcaacagcagcagcagcagcacgcaaCCACCTCGCACTCCGGCTCCGGCGTGGAGCAGTCAAGCAATTTTATAGCCGCACTCGCGGCCGTCGACTGCTGCAGCGTGGCGGCCGTTGACAGTGATGCCAAGTACTTGGATCTGGATGCCTGCAAGCGGGAGCAGctcagcaatagcagcagccaTTTGCCCTCGGCCTCTGCGTCCACGTCGACAACATCGTCGTCGTTTGCGGCTGCGCCAACGGAGAGCAGTCTGGTTGGTGGCCTGGGCCTGAATATACGCACCGATGAGAAGATGCCCGCCAAGGGCGAGATCTCCGAGCAGGAGAGCAACTGCGACATCGAGAACTCTTGGAGTCAATCGATGTACGGCGACATATCACAGCGTTACTTTAGGGGCCAGTTCACCGATGGCTACAACCAGCAGCTGGCCGATTGGCGGCACGACTACTATCCGGCCCAGGATCTCAgtggccagcaacagcagacgcAGCGTGAACAAAAGCGCTTTGATTTCAATGCGGTCGCGTCGGAGTACGCGCAGCCGGGCGATCTGGACGCCACCTCGAGCTCGACGAGAAACAATCATTTGCTGGATGCACAGCCCACCACTTCCACGTCGTCGTCGGCTATGCTGGCTGGTCCACCAATAGCCTCGACATCCCGTGCGGCCGCCGAGGCGGAGGCCGTGGCCGCGGCGCTGGCGCAACGGAAGCCGCCGCGGCGCAAGATCTACAAGTGTCCGCACTGTGCGGCCATCTTTGAGAAGCTCAAGGAGCGCAACGCGCACATGATCGCCGAGCACAACTATGTGCGCCAGAATCGACGTCTCATCTGCACGCTGGCGTCGCATATGCCACAGCCGCAGGCTCAACAGgatccgcagcagcagcaacaacagcagcagcagcagcatctcaTGCTGCAGGCGGGGCACAGCAATGACGATGTCTTGCACGAGGACTCCAAGGATGGCATTGTGAAGATCAAGCAGGAGCACTGTCAGGATAAACAGGATTCGACGGATCAGCTGCTTGGCCACATGGACCTGCCCGACGTCAAGGACACGGGCCTGCTCGATGCCACCAATGAGAACGGCCCCGATGCGGACGTGAAGCCACCAACCAGCGTCACAGAGCTGGACGAGAAGCCCACCATAGCGCCGTTGGCCATGACCACGCCCGCTGCCAAACTGGCCGCCCTCTATCGCATGCTCATCGCCTACAACGAATCGAAGCTCGGCCAGGAGCGCAACAATCTCAGCGAGCTGGAACAGAAGGCCATGGAGAAGTCCATATTCCTTTGCTACGTCTGCCGCACCGATTTCCCCTCGGTGAAGTTGTACGATGCGCATCTGACCGAGCATCCGGCCGAGTGTTTCACCTGCGGCAAGAAGTTCTATCGGTGGAAGAACTTCTCGCTGCACCTGAAACGCCATCTCGGCTGGAAGGAGTTCGGCTGCTACGTCTGCGACAAGAAGTTTGTGGTGCGCAGCGCACTCGTGGAGCACATGCGCATGCACACGGGCCAGACGCCGCTCAAGTGCAAGATCTGCGGCAAGAAGTTCAAGCGCTATTCCAACTTGACGCAGCATCGCAAGCGTCACACCAAGATGATGGTGCGCAAGAAGGAGTACGTCTGCCACTGCGGCGAGGTGCTGCCCTCGAAGGCGCGCTTCCTGTGGCACAAGGAGACGCACGACTTGAAGCCCAAATGCTGTCCGTATTGCTGCGATCGTTTCGTGCACGCGAACTCGCTCCGCCGGCACATTCGGCTGGCCCATTCGGACAAGTTCGACTATGCCGAGCCCATGGAGTGTCCCATGTGCAAGCAGATCTTTGCCAAGACATCGATCAAGGCGCACATGGCCACCCACTCGACGGATCCGCAATACGATTGCGCCATTTGCAACAAGAGCTTCTCGACCAAATGGAATCTCAAGATACATTCGTGGGTGCACGCAAATCGCACGGCCAAACCGTTCAAGTGCGAGTACTGCCCGAAGGCCTTCGTGCGCGAGCTGGACTTCAAGAACCACATGAATGCCCACAAGCAGATCAAGCCCTACACCTGCGAGTACTGCGGCTGCAAGTTCATACGCAAGTACAACTATATGCGGCATCGGCGGGAGCATCATGGCAACAAGAAGTTCACCTGCGACCAGTGCGACAAGTCGTTCCATCGCCACTACTATCTGATCGAGCACAGGCGCATCCATACAGGCGAGCGGCCATTCCACTGCACCATCTGTGGCAAGAGCTCGACCACGAAGACCAATCACAACAAGCATCTGAAGATACATCATTCGCGCGATCCGTTCACAGTGGAGGTTTAA
Protein Sequence: MVDNVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNNGLDSALAAAVLSGSAATTEAGGAASSSSSSAPATADVKPIVPASPPTTTATTAIATTSKSAAPKAALHNSSSSSSSSSSSSSSSSCNNNKLSNPPIKAVKSAPPTTEAPATTSNTPTTSSVAAVYSDYRYEQQSQQQQQQHHGFARGATTLVIPQAPQQQQQQHQFLASQQQSAHFAHHPQQQPAMKYTYATALPPPPPPLQLFAQQATATQSHQKPPPAYGAAISQIRSQHNQNKQQQQQQQQQQQQHINVQQNVNLAPPSDKHGKVHAEIFLNPPPPPPPQLTIPSTSAASRLQHTQQPQQQQQQQQQQQQSLAAGSNNSSYVVATYASSWSALMSSSSAGRASSSRQTSSSPFGALLNAAAQAACASPSSSSAASVLRYAESPVAHYLERENGDFIVQETPKHIVECVEKDDGEFSVIERIYQSPPSVLHIHDDDDDDEEEEDEEEDDKGWANSDDEDHGKLVHEHVEDGDDEHEDSRSRVGPKTTTKKSRKAKPNGRKHKRAAKHQPEDEDDFMSIGSSCAESDHQLEEQQPAPAHAQQSHAAPVASASPAQLCTAPSTSSGAAGAAVVAVCSSTASSTQSGSIKSKKNRVTVLSDVPLNMNEYLDLVGNIVASSRIGAARPFAAVAPIPLVKVEKEEPLDDYDSVREAEMESMEQKPSLEHASSSSSSNSCSSSGHGTTSVIRMASTSSSANVATEDLTQPPPMKVEVEPTVLMPQRFSTPAQQRGPKKLVIKPKATATATATATTKKTDNNSTAESSPSISKASTEPVQIKSENVEAATTSGGSSSSILEKHLTSYAAQQARKHTAVNDDDARVLLEFANSKQLPPAGNSNQTTFVVNAASFASAGSVFASSSGSAQKSSKPGDEYILPDDSKLEVDEIVISSSSSYASNMQQQSQHQHQQQSQQQPAQQALQQAQQPSAFTDFNFLYHPSTTTAAAAATATTASNFAPFGIQQQQQQQQQQLQHPHHGSSEATNAATLASSSSNSSALDQDCSMNATFRLAKQQTALGAWYQSQQQQQQQQHATTSHSGSGVEQSSNFIAALAAVDCCSVAAVDSDAKYLDLDACKREQLSNSSSHLPSASASTSTTSSSFAAAPTESSLVGGLGLNIRTDEKMPAKGEISEQESNCDIENSWSQSMYGDISQRYFRGQFTDGYNQQLADWRHDYYPAQDLSGQQQQTQREQKRFDFNAVASEYAQPGDLDATSSSTRNNHLLDAQPTTSTSSSAMLAGPPIASTSRAAAEAEAVAAALAQRKPPRRKIYKCPHCAAIFEKLKERNAHMIAEHNYVRQNRRLICTLASHMPQPQAQQDPQQQQQQQQQQHLMLQAGHSNDDVLHEDSKDGIVKIKQEHCQDKQDSTDQLLGHMDLPDVKDTGLLDATNENGPDADVKPPTSVTELDEKPTIAPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTDPQYDCAICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHMNAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGNKKFTCDQCDKSFHRHYYLIEHRRIHTGERPFHCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00516419;
90% Identity: iTF_00598344;
80% Identity: -