Dgau004100.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila gaucha
Gene Symbol
-
Assembly
GCA_035045545.1
Location
JAWNOY010000087.1:3917029-3922648[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.00038 0.027 15.0 0.5 1 23 146 168 146 168 0.98
2 14 0.00014 0.01 16.4 1.3 1 23 392 414 392 414 0.98
3 14 1.2 89 4.0 0.7 1 23 420 443 420 443 0.94
4 14 1.2 88 4.0 0.2 1 23 470 493 470 493 0.92
5 14 0.0012 0.089 13.4 1.9 3 23 765 785 764 785 0.92
6 14 0.05 3.6 8.4 1.4 1 23 791 814 791 814 0.98
7 14 3.4 2.5e+02 2.6 1.3 2 23 851 872 850 873 0.85
8 14 0.0087 0.62 10.8 0.8 1 23 894 917 894 917 0.97
9 14 0.02 1.5 9.6 0.4 1 23 1132 1155 1132 1155 0.90
10 14 0.00031 0.022 15.3 4.2 1 23 1167 1189 1167 1189 0.98
11 14 4.5e-05 0.0032 17.9 0.1 2 23 1195 1217 1194 1217 0.90
12 14 0.00099 0.071 13.7 3.8 2 23 1226 1250 1225 1250 0.90
13 14 0.048 3.4 8.4 0.6 1 23 1255 1277 1255 1277 0.97
14 14 0.0066 0.47 11.1 1.3 1 23 1283 1306 1283 1306 0.96

Sequence Information

Coding Sequence
ATGGCGCACAAGCGAGTGAAAACAGAGGACAtggaaataaattacaaattttcgTGTCGCTGTTGCCTCAAATCCGAGGCAGAATTCTACAAGCTGGACTCGCTAATCGAGTGCGGTACTGGCGACAATGACGCGTCCTCTACAAAAATACCCCTCTTACGTTTACTATTGTTCTGCATGCGCATTGAAAATCAGCCCGAGCTGCCGCAGTACATTTGCGTGGAGTGCAGTAAAAGTTTGCAAATAGCCTACTATTTCATACAGAACGGCCTGCGTGCACATGAAATACTCTGTCGCAAACTCTGCCCCGGGAAGCTGAAGAGCGCTACGCGTTCCAACGGCCAGCATACAGCACCCTGGCTCGAGCCGAACGAGAGGGACGTTGCGTCCCTGTCCAGGCACAGGGAGCAGAAGCCACAAAAGCCCGCTGTACGACACGAATGCAAAGTATGCGGTGCCATTGTATACAATCGCATGGAGCTCAAACAGCATATACGCATGCATTCAGATGCGTCGAGCCATCAGTGCAAATTGTGCAGCTTTGTAACCCTCAAGCATCGTCAGCTGCCGGAACATTATCGCAAAGTACACGGCCTGACGGCTGCCCAAATCGAGCATCAGCTGAAGATCCGAAGGTCCATGCAAGCAGCTGCAAACGCTATAACAGCGCCGACTGAAATACCAATAGAAAATGCTGACGATGGTCAGGTGAAAGTTTGCACGCTGGAGGATATGGAGTTGCTGATACCCACTGTGCTTACGCCGGAGGATTTTTCGCATCCCCAGCTTGATGCGGAACAGCTGCGTGAAATCGAGCAACAGTTGGCGAGCTCGTTGCCCATTACACAGTCCACAAGCCTGCCTGCTGGGCCAACGATAGGCACTCCCAATAGTGCCAATGTAAGCATAGGTGCCGAGTTTCTCGTCATGCCCGATGGCTCGTTGCAGCAAGTGAATGATGGCGGTGTAGTATTCGAGTACATTGACGACAGCAAAAATGGCAATGCGACAACCAATATGACATTGCAGAATCTATTGGATGATTCCAAGTCTGATTTAACATATAATGCAATGGATATCGACTTGAGTCATATGATTGTGGACCATGCGCTGCCACAGATAACAGTCAAGCCAAAGCCACGCCCAGCACCTGCGTCCAGTGGCGCCCTTAAACATAAATGTAAGCTATGTCCTAAAGCATTTCCCACGGTCGCGCGCCTGAAATCTCATCAATTAACGCATAGTCATTTGCCTAAATTCTATTGCGATCAGTGCTCTTATTATTCGCTACGCAGCGCCGATCTCATTCAGCACTATTCGACGGAGCACAAGTCCTGTGTTAGCGAGAGTCGTTCGAATAATTTTGATAGGTCGCAGCTGATGATGCCGGCAGACAGAAGTCGCATTTATTCATGCGATATGTGTCTGTTCGAGGCGCCCAGCAGTGGGCAGTTGCGTGTTCACTATAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAACTGCGTCCCAGCTGGACGCATGAGCCTAAGCAGAGGACCGCCAATGCAATGCTAAACAGTGGCAATGCTACCAGTCAGCCAGATATTCCACTAGGCATTAAATATCCACCCATTACGTCAgcgacaacaactgcaatCTCTTCGTCATCAACTACGATGACGCATTCGGCGCAAGcagtcacaacaacaacaactgtggtAACTCCTATGAATGACATTAATGTTGTGGTGGATACCACATCATTGTTTTATGCAGCAACTGCGGAGCAGTTACCAAATACCAATgctgcaacatcagcaacaacagcagcaacggaTTCAAACACATTTGCAATATTTCCCGAGCAATCTTTTGCCAATAgtctaacaacaacaacaacaacaacgccaacaacacTATCAATAGATGCAAACAGTGCGGCAACTGCCACATCGGCCACAACAAATCCAAACACAAGCATATTTGGTGATATGCAGGATTTTATAGATAACACCGATGTGGCTGCCATTTGTACCATACCCGCAGATGATATGCCTGTCGTTGATGGCGATGACATTGTTATTGATAACAATAACATAAGCTTAGATTTTGATGCGGAAAATCTATTTGAGGACTTCGAGGATGTCGAGGTGGGGGAAGAGGATGACGAAGATGAGGAAGATGCCGAAAACGATGATGAGAATGACAACAACGATGCGGCTGCTGATCAAAATCTGCTACTCACCAGTGACGATGACGATGTGGATGACTTTGATGACGAACAGTCAAAGCATCTGCAGAAACCGTATTGCATCTATTGTAATAAAAAGTTCACAAGCCAATATAAGTTCGAGAATCACATGTTTGTGCATCGCGGTTTGGCGCCCTATCGCTGTGAGCTGTGTACGAACTTGTACAATATGAAGCGCCTGCTGATTCGACATTATAAGACGGTGCATAAGCGCATGCCCACGCGGGACATGGTGCAGGCCAAGGGCGACAAGGTGTCTGTGGCGCGTACAACCATTGAAAAGATAAATGTTCATGTTGACAAAACTCCTATGCTAATGTGTGCAAAGTGTCCTTTTGAATGCGAGTTGGAGGGTGAAATGCGAAAACATCTAAATGCGCATCATGGCATCAACGATGGTGGCTCTTCGCAGGCCAACGAGGTGTTTATCATTCGCAAACTGCCCTATGACTGTCCACGCTGTATTCGCTCCTTTGCTGCTAAGCGCACGCTCACACGACATTTGCAGCGTAGCCATTTAGTGGACACTATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCGGCCACCACGACCACATCGACGGCAACAACGACATTGCCGCTGAATGCCAGCGATgacaataaaacaacaacaacaacagcagtcgGATCAACAACTCAACTGGATTCGAACATGTTGGCGCAGCATGACGCTGACTCTgtcgatggcgatggcgatggagATGGTGATGGAGAAGGCGATGGAAAATGCGACAGGGACACAGGACGCACAACGGAAAATGTAAGCACTTCTATGATAGCCGAAGCAGCGCAAGAGACAAACgatgcagcaacaactgaaATTATAGACAGTGCAGCAATAACAAACACAGAAGTCACAGAAGCTGAAACAACATCAATAACAACTGAAGTAGTACCATCAACAACAACCGCTGGCTCGACACTCTTTCCAACGCCCACGCCTTTTGATTTTGATCTTGACTTTATGGGCGATGGTGAGCATGCCACGACCCTCAAGAACAGCAACGACAGCTTCAGCATTGTACCTAATCCCAGTCATCTATTGAATGGCACCGATAAGCTACTGACTGCTGCGTTGGACCCATCGCCAGTTAAAGATCTACGCACACGCATGCCACGTACTCCCATTTTTGTGTGCAAGCAATGTAATCAGACCTTCGATGAGCTCGGCAAGCTGTTGCAGCACGAATTGGACCAACATTCCAGCGGCATTGTTTCTCGCAACAATTACCAGCATCAGTGCAAGATCTGTAACACAACATATCGCACTGTAACATTACTTAACTATCATATGAAACGGCATACACCTGTCAGAATTGTATGCAAACAGTGTCCCAAAGAATTTTCGAACAGCTCTGATTTGGAGCAGCATGCTTTGGCACAGCATAGCATCAGTTCACAGACGCCGCTCAAATGCGGTGTGGATGGTTGCACAAAGACATTTAACTACAAACATCATTTAAAACGGCACCAGACAGCCTCCCATACGCCTGTGCAGTATATCTGCCCGGAGTGCGGACGCGATATGCTGACCAGTCTGCATCTGAGGAATCACATGTCCAGCCACAAGAGCACACACTCTTATAAGTGTCCCAAATGCGTGCGCACCTATATGAGACGCAATCCGTTCCGCAGACATGCGCTACGTGAGCACAAATGGGAACTGACCGAGCAGGAGATTGATAACATTTATTGCGTTAATGACACACCGCCAATAAGTAAATTGAGGGGACGCAGATCGTTGAAGGTTGAGAGCGAGCAGTCTGATTAG
Protein Sequence
MAHKRVKTEDMEINYKFSCRCCLKSEAEFYKLDSLIECGTGDNDASSTKIPLLRLLLFCMRIENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKSATRSNGQHTAPWLEPNERDVASLSRHREQKPQKPAVRHECKVCGAIVYNRMELKQHIRMHSDASSHQCKLCSFVTLKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQAAANAITAPTEIPIENADDGQVKVCTLEDMELLIPTVLTPEDFSHPQLDAEQLREIEQQLASSLPITQSTSLPAGPTIGTPNSANVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNGNATTNMTLQNLLDDSKSDLTYNAMDIDLSHMIVDHALPQITVKPKPRPAPASSGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYSTEHKSCVSESRSNNFDRSQLMMPADRSRIYSCDMCLFEAPSSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQRTANAMLNSGNATSQPDIPLGIKYPPITSATTTAISSSSTTMTHSAQAVTTTTTVVTPMNDINVVVDTTSLFYAATAEQLPNTNAATSATTAATDSNTFAIFPEQSFANSLTTTTTTTPTTLSIDANSAATATSATTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDEDEEDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTTIEKINVHVDKTPMLMCAKCPFECELEGEMRKHLNAHHGINDGGSSQANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDDNKTTTTTAVGSTTQLDSNMLAQHDADSVDGDGDGDGDGEGDGKCDRDTGRTTENVSTSMIAEAAQETNDAATTEIIDSAAITNTEVTEAETTSITTEVVPSTTTAGSTLFPTPTPFDFDLDFMGDGEHATTLKNSNDSFSIVPNPSHLLNGTDKLLTAALDPSPVKDLRTRMPRTPIFVCKQCNQTFDELGKLLQHELDQHSSGIVSRNNYQHQCKICNTTYRTVTLLNYHMKRHTPVRIVCKQCPKEFSNSSDLEQHALAQHSISSQTPLKCGVDGCTKTFNYKHHLKRHQTASHTPVQYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTEQEIDNIYCVNDTPPISKLRGRRSLKVESEQSD