Basic Information

Insect: Drosophila mulleri
Gene Symbol: -
Assembly: GCA_035047565.1
Location: JAWNPK010000168.1:14602599-14608137[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00022 0.017 15.7 0.7 1 23 147 169 147 169 0.98

2 14 0.00014 0.011 16.3 1.7 1 23 395 417 395 417 0.98

3 14 1.6 1.2e+02 3.5 0.8 1 23 423 446 423 446 0.94

4 14 0.83 64 4.4 0.2 1 23 473 496 473 496 0.92

5 14 0.0012 0.091 13.4 1.9 3 23 773 793 772 793 0.92

6 14 0.047 3.6 8.3 1.4 1 23 799 822 799 822 0.98

7 14 2.7 2.1e+02 2.8 1.5 3 23 860 880 858 881 0.87

8 14 0.012 0.95 10.2 0.5 1 23 902 925 902 925 0.97

9 14 0.038 2.9 8.6 1.1 1 23 1165 1188 1165 1188 0.91

10 14 0.00029 0.022 15.3 4.2 1 23 1201 1223 1201 1223 0.98

11 14 0.0025 0.19 12.3 0.1 2 23 1229 1251 1228 1251 0.88

12 14 0.0012 0.096 13.3 4.2 2 23 1260 1284 1259 1284 0.89

13 14 0.011 0.89 10.3 0.8 1 23 1289 1311 1289 1311 0.97

14 14 0.12 9.3 7.1 1.2 1 23 1317 1340 1317 1340 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00022	0.017	15.7	0.7	1	23	147	169	147	169	0.98
2	14	0.00014	0.011	16.3	1.7	1	23	395	417	395	417	0.98
3	14	1.6	1.2e+02	3.5	0.8	1	23	423	446	423	446	0.94
4	14	0.83	64	4.4	0.2	1	23	473	496	473	496	0.92
5	14	0.0012	0.091	13.4	1.9	3	23	773	793	772	793	0.92
6	14	0.047	3.6	8.3	1.4	1	23	799	822	799	822	0.98
7	14	2.7	2.1e+02	2.8	1.5	3	23	860	880	858	881	0.87
8	14	0.012	0.95	10.2	0.5	1	23	902	925	902	925	0.97
9	14	0.038	2.9	8.6	1.1	1	23	1165	1188	1165	1188	0.91
10	14	0.00029	0.022	15.3	4.2	1	23	1201	1223	1201	1223	0.98
11	14	0.0025	0.19	12.3	0.1	2	23	1229	1251	1228	1251	0.88
12	14	0.0012	0.096	13.3	4.2	2	23	1260	1284	1259	1284	0.89
13	14	0.011	0.89	10.3	0.8	1	23	1289	1311	1289	1311	0.97
14	14	0.12	9.3	7.1	1.2	1	23	1317	1340	1317	1340	0.95

Sequence Information

Coding Sequence: ATGGCGAACAAGCGAATAAAAACAGAGGGCATGGAAACGAATTACAAATTTTCGTGTCGCTGTTGCCTCAAATCCGAAGCGGAATTCTACAAACTGGACTCTCTTATTGAGTGCGGCAGTGGCGAAAATGACGCGTCCTCTACGAAATTGCCCCTTCTGCGTTTACTATTATTCTGCATGCGCATCGAAAATCATCCCGAGCTGCCGCAATACATATGCGTGGACTGCAGTAAGAGTTTGCAAATCTCCTACTATTTCATACAGAACGGACTGAGAGCACACGAAATACTCTGTCGGAAACTGTGCCCCGGCAAGCTAAAGCTAAACTCACCGCGCTCCAATGGTCAACAGCCAACGCAGAGGATCGAGtCGAACGACAGCGAGGATGCGAAGCAGTCCAGACTCTTGGATCAAAAGCCACAAAAGACCATGACGCGGCACGAGTGCAAAGTGTGCGGGGCCATGGTATACAATCGCATGGAGCTCAAGCAGCACATACGCATGCACGCAGATGCATCGAGTCATCAGTGCAAATTGTGCAGCTTTGTCACGTACAAGCACCGCCAGCTGCCGGAACATTATCGCAAAGTACATGGCCTGACGGCTGCCCAAGTCGAGCATCAGCTCAAGATCCGCAGATCCATGCAGGCAGCTGCAAACGCTATAAAATCACCACCAAAACCACCAATAGAACTAGGAGCTGGCGAGGAGCCAGTGAAGGTCTGCACTCTGGAGGATATGGAACTGCTGATACCCACCGTGCTGACGCCAGAAGATTTTTCGCATCCTCAACTTGATGCGGATCAGCTGCGTGATATAGAGCAACAATTGGCGAACTCGTTGCCCGTTGCACACTCCATCAGCCAACCGGCTGAGCCAACAATAGGGAGTGGCAATAGCGCCAATGTAAGCATAGGTGCCGAGTTTCTGGTCCTGCCCGATGGCTCCTTGCAGCAAGTGAATGATGGCGGTGTGGTATTCGAGTACATTGACGACAGCAAAAACGGTAATGCGTCGACAACTAACATGACATTACAGAGCCTACTGGATGATTCCACGCCTGACTTAACATATAGTGCAATGGACATCGACTTAAGTCATATGGCTGTGGGCAATGCATTGCCCCAGATAAAAGTCAAGCCGAAGGCGCGACCAGCACCCGCGTCTACTGGCGCCTTGAAACATAAATGCAAGCTGTGTCCAAAAGCATTTCCCACAATGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCAAAATTCTATTGTGATCAGTGCTCCTATTATTCGCTACGCAGTGCCGATCTCATCCAGCATTATACGACGGAACACAAGTCCGGCGTTGGCGATAATCGTTCGAATCAATTGGATAGATCCCAATTCTTTTCGCCGGCTGATAAAAGTCGCATTTATTCCTGCGATATGTGTCTGTTCGAGGCGCCAACCAGTGGGCAACTGCGTGTACACTACAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAGCTGCGCCCCAGTTGGACGCATGAGCCGAAGCAGGGGAGCACTAATTCAACGGTAAACAGTGGCAGTGCCTCCAGACAGCCCGATATTCCACTTGGGATAAAATatCCTCCCATGACGTCAACGGCAtccactgcagcaacaacattaacaaatgCGTTGGCGTCACCAACTTTGCAatcaccaacagcaacagtaacaacaacaacaacaacagtgggAACATCCATGAATGAGCTTAATGTTGTGGTGGATACCACAGCATTGTTCtatgcagcaactgcagagCAGTTACCGAATACTGATGCGACAACATCAGTAACGACGGCAGCTACAGaatcaaatacattttcaatattcccAGAGCAATCGTTTGCTAACAGTctaacaacaccaacagcaactccgccaacaattgcagcagacGCAAACGGTGCGGCAACCGCTACATCGGCTACAACAAATCCAAACACAAGTATATTTGGTGATATGCAGGATTTTATAGATAATACCGATGTGGCTGCCATTTGTACCATACCCGCCGACGATATGCCTGTCGTTGATGGAGACGATATtgttattgataataataatatcagtTTGGACTTTGATGCTGAAAATCTATTTGAGGACTTTGAAGACGTCGAGGTTGGCGAGGAGGATGAAGAAGACGAGGAGGATGCTGAAAATGAGGATGAAAATGACAACAACGATGCAGCTGCTGATCAGAATCTGCTGCTCACCAGTGACGATGACGATGTGGACGACTTCGATGATGAGCAATCGAAGCATCTGCAGAAACCGTATTGCATCTATTGTAATAAGAAGTTCACCAGCCAATATAAGTTCGAGAATCACATGTTTGTGCATCGCGGTTTGGCGCCGTATCGCTGTGAGCTGTGCACCAATCTGTACAATATGAAACGACTGCTCATTCGACATTATAAGACAGTGCATAAACGCATGCCAACACGGGACATGGTGCAGGCCAAGGGCGATAAGGTGTCTGTGGCCCGTACAGCCATTGAGAAGATAAATGTTCACGTTGACAAAAATCCCATGGTAATGTGTGCTAAATGTCCATTTGAATGCGAACTGGAGAGTGAAATGCGCAAACATTTAAGTGCGCATCATGGCATTAACGATGGtgGGACTACGCATGCAAATGAGGTGTTTATCATACGCAAGTTGCCCTATGACTGCCCACGCTGCATTCGGTCCTTTGCGGCTAAGCGCACGCTTATAAGACATCTGCAGCGCAGCCATTTAGTGGACACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCGGCGGCAACCACGACCACATCGACGGCAACAACCACGTTGCCGCTCAAGGCTAGTGATGGCaataaaacaacagcagcaacaactacatcCGGGACAACAACTCAACTGGATTCGAacatattggcgcagcattTCTCGGACTCTGTGGGTGGTGATGGCAATGGTAATGGTGGAGGCGATGGCAacggcgatggcgatggcgatggcgatggcaatggcaatggaaaaTGCGACAGGGACACAGGATACACAACGGAAAATGTAACCACAAATATACAAACCGAAGCACCACAAAACACAATCGATGCAACTACAATTGAACCTACAGAACCTACTGGATCAACAGAACCAGCAAACACTGAAACCACAAAAGCAGAAACAccatcaataacaacaacaacaacaacagtaacaacaacaagtgaagaagggccagcaacaacatcaactgcTGGCTCAACACTCTTTCCAACGCCCACGCCATTTGACTTCGATCTTGATTTTATGGGCGATGGAGAGCATGCCACGACCATTAGGAACAGCGACAGCTTCAGCATTGCACCCAATCACACTCATCTATTGAATGGAACCGATAAGCTATTGACTGATGCGTTGGAGCCATCGCCAGTTAAAGATCTGCGCGCACGCCTACCCCGTACCCCTATCTTTGTGTGCAAGCAATGTAATCACACCTTTGATGAGCTTGGCAAGCTGCTGCAACACGAGTTGGAGCAACATTCCAGCGGCGTTATATCGCCGCGCAATAGTTACCAGCACCAGTGCAAGATCTGCAATACAACATACCGCACCGTAACGCTACTTAATTATCACATGAAACGGCATACGTCAGCAAAAGTTTCATGTAAACAGTGCCCCAAAGAGTTTGCAAACATATCCGATTTGGAGGTGCATTCACTGGCGGAGCATAGTGTCGGAGCACAGACGCCTCTCAAATGCGGCATTAATGGCTGCACTAAGACATTTAACTACAAACATCATCTGAAACGGCATCAGACTGCCTCGCACACGGCCGTGCAGTATATTTGCCCAGAATGCGGACGCGATATGCTTACTAGTCAGCATCTCAGGAATCATATGTCCAGCCATAAGAGCACACACTCTTACAAGTGTCCCAAATGTGTGCGAACTTATTTGAGGCGCAATCCTTTTCGCAGACATGCGCTACGGGAGCACAAGTGGGAGCTGACCGAGCAGGAGATTGATCAAATTTACTGCATTAATGAAATACCGACTGTGGGTAAATTTCGTGAGCGCAGATCGTTGAAGGTTGAGATCGACCAGGCAGACTAG
Protein Sequence: MANKRIKTEGMETNYKFSCRCCLKSEAEFYKLDSLIECGSGENDASSTKLPLLRLLLFCMRIENHPELPQYICVDCSKSLQISYYFIQNGLRAHEILCRKLCPGKLKLNSPRSNGQQPTQRIESNDSEDAKQSRLLDQKPQKTMTRHECKVCGAMVYNRMELKQHIRMHADASSHQCKLCSFVTYKHRQLPEHYRKVHGLTAAQVEHQLKIRRSMQAAANAIKSPPKPPIELGAGEEPVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEQQLANSLPVAHSISQPAEPTIGSGNSANVSIGAEFLVLPDGSLQQVNDGGVVFEYIDDSKNGNASTTNMTLQSLLDDSTPDLTYSAMDIDLSHMAVGNALPQIKVKPKARPAPASTGALKHKCKLCPKAFPTMARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSGVGDNRSNQLDRSQFFSPADKSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQGSTNSTVNSGSASRQPDIPLGIKYPPMTSTASTAATTLTNALASPTLQSPTATVTTTTTTVGTSMNELNVVVDTTALFYAATAEQLPNTDATTSVTTAATESNTFSIFPEQSFANSLTTPTATPPTIAADANGAATATSATTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDEEDEEDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTAIEKINVHVDKNPMVMCAKCPFECELESEMRKHLSAHHGINDGGTTHANEVFIIRKLPYDCPRCIRSFAAKRTLIRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLKASDGNKTTAATTTSGTTTQLDSNILAQHFSDSVGGDGNGNGGGDGNGDGDGDGDGNGNGKCDRDTGYTTENVTTNIQTEAPQNTIDATTIEPTEPTGSTEPANTETTKAETPSITTTTTTVTTTSEEGPATTSTAGSTLFPTPTPFDFDLDFMGDGEHATTIRNSDSFSIAPNHTHLLNGTDKLLTDALEPSPVKDLRARLPRTPIFVCKQCNHTFDELGKLLQHELEQHSSGVISPRNSYQHQCKICNTTYRTVTLLNYHMKRHTSAKVSCKQCPKEFANISDLEVHSLAEHSVGAQTPLKCGINGCTKTFNYKHHLKRHQTASHTAVQYICPECGRDMLTSQHLRNHMSSHKSTHSYKCPKCVRTYLRRNPFRRHALREHKWELTEQEIDQIYCINEIPTVGKFRERRSLKVEIDQAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00473325;
80% Identity: -