Basic Information

Insect: Drosophila aldrichi
Gene Symbol: -
Assembly: GCA_035045965.1
Location: JAWNOM010000374.1:2785360-2790962[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00022 0.016 15.7 0.7 1 23 147 169 147 169 0.98

2 14 0.00014 0.01 16.3 1.7 1 23 395 417 395 417 0.98

3 14 1.6 1.2e+02 3.5 0.8 1 23 423 446 423 446 0.94

4 14 0.43 32 5.3 0.4 1 23 473 496 473 496 0.92

5 14 0.0012 0.087 13.4 1.9 3 23 769 789 768 789 0.92

6 14 0.047 3.5 8.3 1.4 1 23 795 818 795 818 0.98

7 14 7 5.2e+02 1.5 1.1 3 23 856 876 854 877 0.85

8 14 0.012 0.91 10.2 0.5 1 23 898 921 898 921 0.97

9 14 0.047 3.5 8.3 1.1 1 23 1154 1177 1154 1177 0.90

10 14 0.00029 0.022 15.3 4.2 1 23 1190 1212 1190 1212 0.98

11 14 0.024 1.8 9.2 0.0 2 23 1218 1240 1217 1240 0.89

12 14 0.0012 0.092 13.3 4.2 2 23 1249 1273 1248 1273 0.89

13 14 0.045 3.3 8.4 0.6 1 23 1278 1300 1278 1300 0.97

14 14 0.0063 0.46 11.1 1.3 1 23 1306 1329 1306 1329 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00022	0.016	15.7	0.7	1	23	147	169	147	169	0.98
2	14	0.00014	0.01	16.3	1.7	1	23	395	417	395	417	0.98
3	14	1.6	1.2e+02	3.5	0.8	1	23	423	446	423	446	0.94
4	14	0.43	32	5.3	0.4	1	23	473	496	473	496	0.92
5	14	0.0012	0.087	13.4	1.9	3	23	769	789	768	789	0.92
6	14	0.047	3.5	8.3	1.4	1	23	795	818	795	818	0.98
7	14	7	5.2e+02	1.5	1.1	3	23	856	876	854	877	0.85
8	14	0.012	0.91	10.2	0.5	1	23	898	921	898	921	0.97
9	14	0.047	3.5	8.3	1.1	1	23	1154	1177	1154	1177	0.90
10	14	0.00029	0.022	15.3	4.2	1	23	1190	1212	1190	1212	0.98
11	14	0.024	1.8	9.2	0.0	2	23	1218	1240	1217	1240	0.89
12	14	0.0012	0.092	13.3	4.2	2	23	1249	1273	1248	1273	0.89
13	14	0.045	3.3	8.4	0.6	1	23	1278	1300	1278	1300	0.97
14	14	0.0063	0.46	11.1	1.3	1	23	1306	1329	1306	1329	0.96

Sequence Information

Coding Sequence: ATGGCGAACAAGCGGGTAAAAATAGAGGGCATGGAAACGAATTACAAATTTTCGTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTACAAACTGGACTCGCTAATCGAATGCGGCAGTGGCGAAAATGACGCGTCCTCTACGAAAATACCCCTACTGCGCTTACTATTATTCTGCATGCGCATCGAAAATCAGCCCGAGTTGCCGCAATACATATGCGTGGAGTGTAGCAAGAGCTTGCAAATCTCGTACTATTTCATACAGAACGGACTGAGAGCACACGAAATACTCTGTCGGAAACTGTGCCCCGGCAAGCTAAAGCTGAACTCACCGCGTTCCAATGGTCAACAGCCCTCGCAGAGGCTCGAGTCGAACTACAGCGAGGATGCGAAACAGCCCAGACTCTTGGATCAAAAGCCACAAAAGACCACGACACGGCACGAATGCAAAGTGTGCGGGGCCATGGTATACAATCGGATGGAGCTCAAGCAGCACATACGCATGCACGCAGATGCATCGAGTCATCAGTGCAAATTGTGCAGCTTTGTCACGTACAAGCACCGCCAGCTGCCGGAACATTATCGCAAAGTACATGGCCTGACGGCTGCCCAAATCGAGCATCAGCTCAAAATCCGCAGTTCCATGCAGGCATCTGCAAACGCAATAAAGTCACCGCCAAAACTACCAATAGAACCAGGAGCTGGCGAGGAGCCAGTAAAGGTCTGCACTCTGGAGGATATGGAACTGCTTATACCCACCGTGCTGACGCCAGAAGATTTTTCGCATCCTCAACTTGATGCTGATCAGCTGCGTGATATAGAGCATCAATTGGCGAACTCGTTGCCCGTTGCACACTCCATCAACCAGCCGGTTGAGCCAACGATAGGGAGTGTGAATAGCGCCAATGTAAGCATAGGTGCCGAGTTTCTGGTCATGCCCGATGGCTCCTTGCAGCAAGTGAATGATGGCGGTGTGGTATTCGAGTACATTGACGACAGCAAAAACGGTAATGCGTCGACAACTAACATGACATTACAGAGCCTACTGGATGATTCCAAGCCTGACTTATCATATAGTGCAATGGACATCGACTTAAGTCATATGGCTGTGGGCAATGCATTGCCACAGATAAAAGTCAAGCCGAAGGCGCGACCAGCTCCCGCGTCTACTGGCGCCCTGAAACATAAATGCAAGCTGTGTCCAAAAGCATTTCCTACGATGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCAAAATTCTATTGCGATCAGTGCTCCTATTATTCGCTACGCAGCGCCGATCTCATCCAGCATTATACGACGGAACACAAGTCTAGCGTTGGCGATAATCGTTCGAATCAATTGGATAGATCCCAATTACTTTTGCCGGCAGATAAAAGTCGCATTTACTCCTGCGATCTGTGTCTGTTTGAAGCGACAACCAGTGGGCAACTGCGTGTACACTACAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAACTACGTCCCAGTTGGACGCATGAACCGAAGCAGGGGGGCGCTAATACAATGGTAAACAGTGGCAATGCTTCTAGCCAGCCCGATATTCCACTTGGCATAAAATatCCTCCCATGACGGCAACGGCATccactgcagcaacaacattaacaactGCGTTGGCGGCACCAGCTCTggactcaacaacaacaacagcaccaactGTGGGAACACCTATAAATGAGCTTAATGTTGTGGTGGATACCACAGCATTGTTCTATGCAGCAACTGCAGAGCAGTTACCGAATGCTGATGCGACAACATCAGTAACGACGGCAGCTACAGaatcaaatacattttcaatattccCAGAGCAATCGTTTGCTAATAATctaacaacaccaacaacaactccgtcaacaattgcagcagacGCAAACGGTGCGGCAACTGCCACGTCGGCCACAACAAATCCAAACACGAGTATTCTTGGTGATATgcaagattttatatataataccgATGTGGCTGCCATTTGTACCATACCCGCCGATGACATGCCTGTCGTTGATGGAGATGATATtgttattgataataataatatcagtTTGGACTTTGATGCGGAAAATCTATTTGAGGACTTTGAAGATGTCGAGGTTGGCGAAGAGGATGATGAAGACGAGGAGGATGCTGAAAATGAGGATGAAAATGACAACAACGATGCGGCTGCTGATCAGAATCTGCTGCTCACCAGTGACGATGACGATGTGGACGACTTCGATGATGAACAATCGAAGCATCTGCAGAAACCTTATtgcatatattgtaataaGAAGTTCACCAGCCAATATAAGTTCGAGAATCACATGTTTGTGCATCGCGGTTTGGCGCCGTATCGCTGTGAGCTGTGCACCAATCTGTACAATATGAAGCGACTGCTCATTCGACATTATAAGACGGTGCATAAACGCATGCCAACGCGGGACATGGTGCAGGCCAAGGGCGACAAAGTGTCTGTGGCCCGTACAGCCATTGAGAAGATAAATGTTCACGTTGACAAAAATCCCATGGTAATGTGTGCTAAATGTCCATTTGAATGTGAACTGGAGGGTGAAATGCGCAAACATTTAAGTGCGCATCATGGCATTAATGATGGggGGTCTACGCATGCCAATGAGGTGTTTATCATACGCAAATTGCCCTATGACTGTCCACGCTGCATTCGGTCCTTTGCGGCTAAGCGCACGCTTATAAGACATCTGCAGCGCAGCCATTTAGTGGACACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCGGCAACCACGACCACATCGACGGCAACAACCACATTGCCGCTCAATGCCAGTGATggtaataaaacaacaacaacatccggGACAACAACTCAACTGGATTCGAACATATTGACGCAGCATTTCTCGGACTCTATCGCTGGtgatggcaatggcaatggtgGAGGTGATGGCaacggcggtggcggtggcgatggcgatggcaatGGAAAATGCGACAGGGACACAGGATACACAACGGAAAATGTAACCACAAATACACAGACCGAAGCACCACAAAACCCAATCGATGCAACCACAACTGAACCTACTGAACCTACTGGATCAACAGAATCAGCAAACACTGAAACCACAGAAGTAGAAACGCcatcaataacaacaacaacggcaacaacaacaactgaagagggaccagcaacaacatcaactgcTGGCTCAACACTCTTTCCGACGCCCACGCCATTTGACTTCTATCTTGATTTTATGGGCGATGGAGAGCATGCCACGACAATTAAGAACAGCGACAATTTCAGCATTGCACCCAATCACACTCATCTATTGAATGGTAGCGATAAGCTATTGACTGCTGCGTTGGAGCCATCGCCAGTTAAAGACCTGCGCACGCGCCTACCCCGTACCCCTATCTTTGTGTGCAAGCAATGTAATCACACCTTCGATGAGCTTGgcaagctgctgcagcacgaGTTGGATCAACATTCCAGCGGCATTATATCGCCGCGCAATAGTTACCAGCACCAGTGCAAGATCTGCAACACAACATACCGCACCGTTACGCTACTTAATTATCACATGAAACGGCATACGTCGGTAAAAGTCTCATGCAAACAGTGCCCCAAAGAATTCGCAAACATATCCGAATTGGAGCCGCATTTACTGGCGGAGCATAGCGTCGCAGCACAGACGCCTCTCAAATGCGGCATTAATGGCTGCACTAAGACATTTAACTACAAACATCATCTGAAACGGCATCAGACTGCCTCCCACACGGCCGTGCAGTATATTTGCCCAGAATGCGGACGCGATATGCTTACTAGTCTGCATCTCAGGAATCATATGTCCAGCCATAAGAGCACACACTCTTACAAGTGTCCCAAATGTGTGCGCACTTATATGAGACGCAATCCTTTTCGCAGACATGCGCTACGTGAGCACAAGTGGGAGCTGACCGAGGAAGAGATTGATCAAATTTACTGCATTAATGATATACCGACTTTGGGTAAACTTCGTGAGCGCAGATCGTTGAGGGCTGAGATCGACCAGTCCGACTAG
Protein Sequence: MANKRVKIEGMETNYKFSCRCCLKSEAEFYKLDSLIECGSGENDASSTKIPLLRLLLFCMRIENQPELPQYICVECSKSLQISYYFIQNGLRAHEILCRKLCPGKLKLNSPRSNGQQPSQRLESNYSEDAKQPRLLDQKPQKTTTRHECKVCGAMVYNRMELKQHIRMHADASSHQCKLCSFVTYKHRQLPEHYRKVHGLTAAQIEHQLKIRSSMQASANAIKSPPKLPIEPGAGEEPVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEHQLANSLPVAHSINQPVEPTIGSVNSANVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNGNASTTNMTLQSLLDDSKPDLSYSAMDIDLSHMAVGNALPQIKVKPKARPAPASTGALKHKCKLCPKAFPTMARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSSVGDNRSNQLDRSQLLLPADKSRIYSCDLCLFEATTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQGGANTMVNSGNASSQPDIPLGIKYPPMTATASTAATTLTTALAAPALDSTTTTAPTVGTPINELNVVVDTTALFYAATAEQLPNADATTSVTTAATESNTFSIFPEQSFANNLTTPTTTPSTIAADANGAATATSATTNPNTSILGDMQDFIYNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDEDEEDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTAIEKINVHVDKNPMVMCAKCPFECELEGEMRKHLSAHHGINDGGSTHANEVFIIRKLPYDCPRCIRSFAAKRTLIRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDGNKTTTTSGTTTQLDSNILTQHFSDSIAGDGNGNGGGDGNGGGGGDGDGNGKCDRDTGYTTENVTTNTQTEAPQNPIDATTTEPTEPTGSTESANTETTEVETPSITTTTATTTTEEGPATTSTAGSTLFPTPTPFDFYLDFMGDGEHATTIKNSDNFSIAPNHTHLLNGSDKLLTAALEPSPVKDLRTRLPRTPIFVCKQCNHTFDELGKLLQHELDQHSSGIISPRNSYQHQCKICNTTYRTVTLLNYHMKRHTSVKVSCKQCPKEFANISELEPHLLAEHSVAAQTPLKCGINGCTKTFNYKHHLKRHQTASHTAVQYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTEEEIDQIYCINDIPTLGKLRERRSLRAEIDQSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00551848; iTF_00479706; iTF_00549787; iTF_00540635; iTF_00554619;
80% Identity: -