Basic Information

Gene Symbol
-
Assembly
GCA_035045945.1
Location
JAWNON010000073.1:14320421-14325815[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.0025 0.18 12.4 0.9 1 23 140 162 140 162 0.98
2 15 6.9 4.9e+02 1.5 3.9 1 23 168 191 168 191 0.96
3 15 0.00013 0.0095 16.4 1.3 1 23 386 408 386 408 0.98
4 15 2 1.4e+02 3.3 1.0 1 23 414 437 414 437 0.94
5 15 0.28 20 5.9 0.3 1 23 464 487 464 487 0.92
6 15 0.0012 0.083 13.4 1.9 3 23 761 781 760 781 0.92
7 15 0.047 3.3 8.4 1.4 1 23 787 810 787 810 0.98
8 15 3.3 2.3e+02 2.6 1.1 3 23 848 868 846 869 0.84
9 15 0.0082 0.58 10.8 0.8 1 23 890 913 890 913 0.97
10 15 0.016 1.1 9.8 0.3 1 23 1128 1151 1128 1151 0.91
11 15 0.00029 0.021 15.3 4.2 1 23 1164 1186 1164 1186 0.98
12 15 1.1e-05 0.00074 19.9 0.2 3 23 1193 1214 1192 1214 0.98
13 15 0.0025 0.18 12.4 4.3 2 23 1236 1260 1235 1260 0.90
14 15 0.045 3.2 8.4 0.6 1 23 1265 1287 1265 1287 0.97
15 15 0.0063 0.44 11.1 1.3 1 23 1293 1316 1293 1316 0.96

Sequence Information

Coding Sequence
ATGGCGTACAAGCGTGTGAAAACAGAGGACATAGAAATGAATTACAAATATTCTTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTTTACAAGCTGGACTCGCTTATCGAGTGCGGCAGTGGCGAAAATGACGTTGCCTCTACGAAAATACCCCTACTACGTTTACTACTATTCTGTATGCGCATCGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTGGAGTGTAGTAAAAGTTTACAAATCGCCTACTATTTCATACAGAACGGTCTGCGAGCCCACGAAATACTTTGTCGAAAACTGTGTCCCGGCAAGCTGAAGAACTCAACGCGTTCCAATGGCCAACAGACAACACAATGGCTCGAGTCGAACGAGTGTGATGCGACGCGGTCCAGGCTACAGAAGCCCATGGCACGGCACGAATGTAAAGTGTGCGGTGCCACTATATACAATCTTATGGAGTTCAAACAACATATACGCATGCACGCAGattcAGCGAGCCATCAGTGCAAATTGTGCAGCTTTGTGACGCCCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAAGTACACGGCCTGACGGCTGCCCAGATCGAGCATCAGCTTAAGATACGTAGATCCATGCAGGCAGCCGCAAATGCAATAACAGCACCGACAAAAGTACCATTCGCAACTGGTGAGGACGAGCAAGTGAAGGTTTGCACTCTGGAGGATATGGAACTTTTGATACCCACTGTGTTGACACCAGAAGATTTTTCGCAGCCTCAACTTGATGCCGATCAGCTGCGTGATATAGAGCAACAATTGGCGAAAGTGCCCATTACAcagaccagcagcagccagccagctgagCCAACGATAGGAAGTAGCAATAGCGCCAATATGAGCATAGGTGGCGAGTTTCTGGTCATGCCCGATGGCTCCTTGCAGCAAGTGAATGATGGCGGTGTAGTGTTCGAGTATATTGACGATAGCAAAAACGCCAATGGGTCAACAAATATCACGTTGCAGAATCTATTGGATGATTCCAAGACCGATTTAACATATAATGCAATGGATATCGACTTAAGTCATATGGTTATGGGCAATGCGTTGCCACAGATAACAGTCAAGCAAAAGCCGCGCCCAGCACCCGCGTCCACTGGCGCCCTGAAACATAAATGCAAACTATGTCCAAAAGCATTTCCCACGGTCGCACGTCTGAAATCTCATCAATTAACGCATAGTCATCTGCCTAAATTCTATTGCGATCAGTGCTCGTATTATTCGCTACGCAGCGCCGATCTCATACAGCACTATACGACGCAGCACAAATCCTGCGTTAGCGAGAGTCGTTCGAATCATTTGAATAGATCACAATTAACAGTGTCGTCGGATAGAAGTCGCATTTATTCCTGCGATATGTGTCTGTTCGAGGCATCAACCAGTGGACAATTGCGTGTACACTACAGCGATAAGCATCAGATAGTGCCCACTGAGGTGCAGCTGCGTCCCAGTTGGACGCATGAGCCAAAGCAGGGGAGCGCCAATACAATGCTAAACAGTGGTTCCAGCCAGCCCGATATTCCACTAGGCATCAAATatCCTCCCATGACGACAGCGGCtatagcaacggcaacggtaactgctgcagcaacttCGTCAACAACTGCATTGGAGCAGCCGACACTGgaatcgacaacaacaacactggTGACACCtatgaataatattaatgttGTGGTGGATACCACATCATTGTTCTATGCAGCGACTGCAGAGCAGTTACCAAATACTAATGCGACAGAAtcagtaacaacagcagcaacagaatccaacacattttcaatatttcctGAGCAATCATTTGCTAACAGTCTAACGACACCAACCTCAACGCCGACAAAACTTTCAGTAGACGGCAACGGTGTGGCGGCAACAACCACATCGGCTACAGCAAATCCAAACACAAGCATATTTGGTGATATGCAGGATTTTATAGATAATACAGATGTGGCTGCCATTTGTACTATACCCGCCGATGATATGCCTGTCGTTGATGGAGATGATATTgttattgataataataatatcagtTTAGATTTTGATGCGGAAAATCTATTTGAAGACTTTGAAGATGTCGAGGTTGGCGAAgacgatgaagatgatgaagatgCTGAAAATGAGGATGAAAATGACAATAACGATGCGGCTGCCGATCAAAATCTATTGCTTACCAGTGACGATGACGATGTGGATGATTTCGATGATGAGCAATCGAAGCATCTGCAGAAACCGTATTGCATCTATTGTAATAAGAAGTTCACCAGCCAATATAAGTTCGAGAATCATATGTTTGTGCATCGCGGTTTGGCGCCATATCGCTGTGAGCTGTGCACAAATCTGTACAATATGAAGCGTCTACTCATTCGGCATTATAAGACGGTGCATAAACGCATGCCCACACGAGACATGGTGCAGGCCAAGGGCGACAAGGTGACTGTGGCCCGTACAGCCATTGAAAAGATTAATGTTCAAGTTGACAAAGATCCCATGGTAATGTGTGCTAAATGTCCATTTGAATGCGAACTAGAGGGTGAAATGCGCAAGCATTTAAATGCACATCATGGCATTAACGATGACGGCTCTACGCATGCCAACGAGGTGTTTATCATACGCAAACTTCCCTATGACTGTCCACGCTGTATTCGATCATTTGCGGCTAAACGCACGCTTACACGGCATTTGCAACGTAGCCATTTAGTGGATACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCGGCCACCACGACCACATCGACGGCAACAACCACATTGCCGCTGAATGCCAATGATGgtaataaaacaacaacagcaacaacaacaacatccgAAGCAACAACTCAACTGGATTCGAACATATTGGCACAGCATTTCGCTGACTCTGTGGTTGGTGATGGCGATGGGGATGGAAAATGCGACAGGGGCACAGGATGCACAGCGGAAACTGtaaatacagatacacaaTCCGAAGCACCACAAGACACCAacgaggcaacaacaactgaaactaTAAAACCCGCTGCTATACCAAACACTGAAGCAACGGAAGATGAATCACcatcaataacaaaaacaactgaagaagtaccaacaacaacacctacAACAGCCCGTGCTTCAACACTCTTTCCAACGCCCACGCCATTTGACTTTGAACTTGATTTTATGGGCGATGGGGagcatgccacgccccttaaGAACAATGACAGCTTCACCCTTACACAGAATGCCAGTCATCTATTGAATGGAATGGATAAGCTACTGACTGCTGCGTTGGAGCCATCGCCAGTTAAAGATCTTCGCACACCTCTGCCCCGTACTCCCATATTTGTGTGCAAGCAATGCAATCAAACTTTCGATGAGCTTGGCAAGCTGGTGCAGCACGAATTGGAGCAACATTCCAGCGGCATTGTATCGCCGCGCATCGGTTACCAGCATCAGTGCAAGATCTGCAATACAACATACCGCACCGTAACACTACTTAACTATCATATGAAACGGCATACGCCAGTAAAACTTTTATGCAAACAGTGCCCCAAAGAGTTTGCAAACAACTCCGATTTGGAGCAGCATATACTGACGGAGCATAGCGTCCAAATACAGTTGCCGCTTAAATGCGGCACGGAGGGCGTCGAAGTACAGTCGCCGCTCAAATGCGGCTTGGAGGGTTGCACAAAGACATTCAACTTCAAACATCATCTGAAACGGCATCAGACAGCCTCCCACACTCGTGTGAAATATATCTGTCCGGAATGCGGACGCGATATGCTTACAAGTCTGCATCTCAGAAATCATATGTCCAGCCACAAGAGCACACACTCTTACAAGTGTCCCAAATGTGTGCGCACCTATATGAGACGCAATCCcTTTCGCAGACATGCGTTACGTGAGCATAAGTGGGAGCTAACCGAGCAGGAGCTTGATCAAAATTATTGCATTAATGATATACCGACTTTGAGTAAATATCGCGGACGTAGATCGTTGTAG
Protein Sequence
MAYKRVKTEDIEMNYKYSCRCCLKSEAEFYKLDSLIECGSGENDVASTKIPLLRLLLFCMRIENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKNSTRSNGQQTTQWLESNECDATRSRLQKPMARHECKVCGATIYNLMEFKQHIRMHADSASHQCKLCSFVTPKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQAAANAITAPTKVPFATGEDEQVKVCTLEDMELLIPTVLTPEDFSQPQLDADQLRDIEQQLAKVPITQTSSSQPAEPTIGSSNSANMSIGGEFLVMPDGSLQQVNDGGVVFEYIDDSKNANGSTNITLQNLLDDSKTDLTYNAMDIDLSHMVMGNALPQITVKQKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTQHKSCVSESRSNHLNRSQLTVSSDRSRIYSCDMCLFEASTSGQLRVHYSDKHQIVPTEVQLRPSWTHEPKQGSANTMLNSGSSQPDIPLGIKYPPMTTAAIATATVTAAATSSTTALEQPTLESTTTTLVTPMNNINVVVDTTSLFYAATAEQLPNTNATESVTTAATESNTFSIFPEQSFANSLTTPTSTPTKLSVDGNGVAATTTSATANPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEDDEDDEDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVTVARTAIEKINVQVDKDPMVMCAKCPFECELEGEMRKHLNAHHGINDDGSTHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNANDGNKTTTATTTTSEATTQLDSNILAQHFADSVVGDGDGDGKCDRGTGCTAETVNTDTQSEAPQDTNEATTTETIKPAAIPNTEATEDESPSITKTTEEVPTTTPTTARASTLFPTPTPFDFELDFMGDGEHATPLKNNDSFTLTQNASHLLNGMDKLLTAALEPSPVKDLRTPLPRTPIFVCKQCNQTFDELGKLVQHELEQHSSGIVSPRIGYQHQCKICNTTYRTVTLLNYHMKRHTPVKLLCKQCPKEFANNSDLEQHILTEHSVQIQLPLKCGTEGVEVQSPLKCGLEGCTKTFNFKHHLKRHQTASHTRVKYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTEQELDQNYCINDIPTLSKYRGRRSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00512961;
90% Identity
-
80% Identity
-