Basic Information

Insect: Drosophila buzzatii
Gene Symbol: -
Assembly: GCA_035045845.1
Location: JAWNOS010000373.1:1076681-1082347[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0074 0.58 11.0 0.4 1 23 147 169 147 169 0.98

2 14 0.00014 0.011 16.4 1.3 1 23 394 416 394 416 0.98

3 14 1.7 1.3e+02 3.5 0.8 1 23 422 445 422 445 0.94

4 14 0.87 68 4.4 0.2 1 23 472 495 472 495 0.92

5 14 0.0047 0.37 11.6 3.9 3 23 774 794 773 794 0.92

6 14 0.049 3.9 8.4 1.4 1 23 800 823 800 823 0.98

7 14 5 3.9e+02 2.0 4.0 3 23 861 881 859 882 0.91

8 14 0.0086 0.67 10.7 0.8 1 23 903 926 903 926 0.97

9 14 0.039 3.1 8.7 1.1 1 23 1146 1169 1146 1169 0.91

10 14 3.8e-05 0.003 18.1 3.5 1 23 1182 1204 1182 1204 0.98

11 14 0.00021 0.017 15.8 0.5 2 23 1210 1232 1209 1232 0.95

12 14 0.0013 0.1 13.3 4.2 2 23 1241 1265 1240 1265 0.90

13 14 0.047 3.7 8.4 0.6 1 23 1270 1292 1270 1292 0.97

14 14 0.0066 0.51 11.1 1.3 1 23 1298 1321 1298 1321 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0074	0.58	11.0	0.4	1	23	147	169	147	169	0.98
2	14	0.00014	0.011	16.4	1.3	1	23	394	416	394	416	0.98
3	14	1.7	1.3e+02	3.5	0.8	1	23	422	445	422	445	0.94
4	14	0.87	68	4.4	0.2	1	23	472	495	472	495	0.92
5	14	0.0047	0.37	11.6	3.9	3	23	774	794	773	794	0.92
6	14	0.049	3.9	8.4	1.4	1	23	800	823	800	823	0.98
7	14	5	3.9e+02	2.0	4.0	3	23	861	881	859	882	0.91
8	14	0.0086	0.67	10.7	0.8	1	23	903	926	903	926	0.97
9	14	0.039	3.1	8.7	1.1	1	23	1146	1169	1146	1169	0.91
10	14	3.8e-05	0.003	18.1	3.5	1	23	1182	1204	1182	1204	0.98
11	14	0.00021	0.017	15.8	0.5	2	23	1210	1232	1209	1232	0.95
12	14	0.0013	0.1	13.3	4.2	2	23	1241	1265	1240	1265	0.90
13	14	0.047	3.7	8.4	0.6	1	23	1270	1292	1270	1292	0.97
14	14	0.0066	0.51	11.1	1.3	1	23	1298	1321	1298	1321	0.96

Sequence Information

Coding Sequence: ATGGCGAACAAGCGAGTAAAAACAGAGGGCATggaaacaaattataaattttcgtGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTACAAACTGGACTCACTAATTGAGTGCGGCAGTGGCGAAAATGACGCGTCCTCTACAAAAATACCCCTTCTACGATTACTGCTGTTCTGCATGCGCATCGAAAATCGGCCCGAGCTGCCGCAATACATATGCGTGGAGTGTAGTAAAAGTTTACAAATAGCCTACTATTTCATTCAGAACGGTCTGCGAGCCCATGAAATTCTCTGTCGGAAACTGTGCCCCGGCAAGTTAAAGTTGAACTCAACGCGTTCCAATGGCCAGCAGACAACGAAATGGCTTGAGTCGAACGAGAGTGAAGATGCGTCGCAGCCTAGACTTTGGGATCAAAAGTCAGAGAAGCCCGTGGCGCGGCATGAATGCAAAGTGTGCGGAGCCGTTATTTACAACCGCATGGAGATCAAGCAACATATACGCATGCACGCAGATTCATCCAGCCATCAGTGCAAATTGTGCAGCTTTGTCACGTACAAGCATCGTCAGCTGCCGGAGCATTATCGCAAAGTACACGGCCTGACGGCTGCCCAAATCGAGCATCAGCTCAAGATCCGCAGATCCATGCAGGCAGCCGCAAACGCAATAACATCACCGACTAAACCACCAATAGATACAGGAGCTGACGATGAGCAAGTGAAGGTTTGCACTTTGGAGGACATGGAACTGCTAATACCCACAGTCTTGACGCCGGAAGATTTTTCGCATCCCCAACTTGATGCGGACCAGCTCCGTGATATAGAGCAACAATTGTCTAACTCGTTGCCCACTACACAGTCCAGCAGCCAGTCAGCCGAGATAACAATTGGGAGCGGTAATAACACCAATGTAAGCATAGGCGCCGAGTTTCTGGTCATGCCCGATGGCTCCTTACAGCAAGTGAATGACGGCGGTGTGGTATTCGAGTACATTGACGATAGCAAAAACGGAAATCCAACATGTAATATGACATTGCAGAGTCTATTGGATGACTCCAAGGCCGATTTAACATATAATGCAATGGACATCGACTTAAGTCATATGGTTGTGGACAAAACATTGCCACAAATAAGAGTTAAGCCGAAGTCGCGTCCAGCACCCGCGTCTACTGGCGCTCTGAAACATAAATGTAAACTGTGTCCAAAAGCTTTTCCTACGGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCaTTTGCCAAAATTCTATTGCGATCAGTGCTCCTATTATTCTTTGCGCAGCGCAGATCTTATCCAACATTATACGACGGAGCACAAGTCCTGTGTTAACGAGAATCGTTCAAATCATTTGGATAGATCACAATTAATTTTGTCGGCAGATAGAAGTCGCATTTATTCCTGCGATATGTGTTTGTTCGAAGCGCCAACCAGTGGGCAATTGCGAGTACATTACAGCGATAAGCATCTTATAGTACCCAGTGAGGTGCAACTGCGACCAAGCTGGACGCATGAGCCGAAGCAGGGTAGCGCTAATACCATGCTAAATAGTGGTAATACTTCCACTCAGCCCGATATTCCACTAGGCATCAAATATCCTCCTATGACGCCAATGACATCAATGGCTAATACTGCAGCAATTACATCTTCAGTAACGCTGGCACCGGCACCTTTGGAATCAACAACCTCAAcatcagcaccagcaacaaagGTGGAAACACCTATGAATGAGCTTAATGTAGTGGTGGATACCACATCATTGTTCtatgcagcaactgcagagCAGTTACCGAATGCTAGTGCGACAACATCAgtaacaacggcagcaacagaatcaaattcattttcaatattcCCCGAGCAGTCTTTTGCGAACAGTCTAAcaacacaaacagcaacaccaCAAACAATATCAGTAGACACAAACGGTGCGGCAGCTACCACATCGGCcacaacaaatcaaaacacAAGCATATTTGGTGATATGCAGGACTTTATAGATAATACCGATGTCGCTGCCATCTGTACTATTCCCGCCGATGATATGCCTGTCGTTGATGGCGATGATATTgttatagataataataatatcagtTTGGACTTTGATGCAGAGAATCTATTTGAGGAGTTCGAAGATGTCGAGGTTGGTGAAGAGGACGAAGAGGATGAAGAAGATGCTGACAACGAGGATGAAAATGACAATAACGATGCGGCTGCTGATCAAAATCTGTTACTCACCAGTGACGATGACGATGTGGATGATTTTGATGATGAGCAATCGAAGCATCTGCAGAAACCGTATTGCATccattgtaataaaaaatttactaGCCAATATAAGTTCGAGAATCACATGTTTGTTCATCGCGGTTTGGCGCCTTATCGCTGTGAGCTCTGCACTAATCTATACAATATGAAACGTCTGCTCATCCGGCATTATAAGACGGTGCACAAACGCATGCCAACTCGGGACATGGTACAGGCAAAGGGCGACAAGGTGTCTGTGGCCCGGACAGCTATTGAAAAGATAAATGTTCATGTTGACAAAAATCCTATTGTAATGTGTGCTAAATGTCCATTTGAGTGTGAATTTGAGAGTGAAATGTGCAAGCATTTAAATGCTCATCATGGCATTAACGATGGtgGCTCTACGCATGCCAATGAGGTGTTTATCATACGCAAGCTGCCCTACGACTGTCCACGCTGTATTCGGTCTTTTGCGGCTAAACGCACGCTTACAAGACACCTGCAACGTAGTCATTTAGTGGACACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCGGCTACCACAACCACATCGACGGCAACAACCACATTGCCGCTGAACGCCAGTGATGGTAAtcaaataacaacagcaacaaccataTCCGGAACAACAACTGAACTGGATTCGAACATATTGGCGCAGCATTTCTCAGACTCTATGGGGCGTGAAGGCATTGGTGGAGGCGAAGGCGATGGAGATGGCGATGGAAAATGCGACAAGGATACAGGATGCGCAACGGAAAATGTAGCCACAGATACACAAACCGAAGCTCCACAAGACACAAACGATGCACCAACAAGTGAAACTACAGAACCAGCAGCAATATCAAACACTGAAGCCACACCAtccataacaacaacaacggtaACATCAACTGAAGAAGGACCAGCGACAAAGACAACATCTAGTTCAACACTCTTTCCAACGCCCACTCCATTTGACTTTGATCTTGACTTTATGGCCGATGGTGAGCATGCCACAGATCATAAGAACAACGATAGCATCAGCATTGCACCGAATCCGAGTCATCTATTGAATGGAATCGATAAGCTACTGACTGCTGCTTTGGAGCCATCACCAGTTAAAGATCTTCGCACGCGCCTGCCCCGTACACCCATATTTGTGTGCAAGCAATGTAATCATACCTTCGATGAGCTTGGCAAGCTGTTGCAACACGAATTGGAACAACATTCCAGCGGTATTGTATCGCCGCGTCTCAGTTACCAGCATCAGTGCAACATCTGCAATACAACATACCGTACCGCAACGTTACTTAACTATCACATGAAACGGCATACGCCAGTAAAAGTTTCATGCAAACAATGTCCCAAAGAGTTTGCGCATATGTCCGATTTGGAGCAGCATTTAGTGACGGATCACAGTGTCGGAGCACAGACACCGCTCAAATGTGGTATGGATGGCTGCACTAagacatttaattataaacatcATCTGAAACGGCATCAGACAGCATCCCACACAGCCGTGCAGTATATCTGTCCTGAATGCGGACGCGATATGCTAACCAGTTTGCATCTCAGGAATCATATGTCCAGTCATAAGAGCACACACTCTTATAAGTGTCCTAAATGTGTGCGCACCTATATGAGACGAAATCCCTTTCGCAGACATGCGCTACGTGAGCACAAGTGGGAGATGACCGAGCAGGAGATTGATCAAATTTACTGCATTAATGATATACCAACTTTGACAAAATATCGCGAACGTAGATCGTTGAAAGATGAGATCGACCATTCTGATTAG
Protein Sequence: MANKRVKTEGMETNYKFSCRCCLKSEAEFYKLDSLIECGSGENDASSTKIPLLRLLLFCMRIENRPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKLNSTRSNGQQTTKWLESNESEDASQPRLWDQKSEKPVARHECKVCGAVIYNRMEIKQHIRMHADSSSHQCKLCSFVTYKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQAAANAITSPTKPPIDTGADDEQVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEQQLSNSLPTTQSSSQSAEITIGSGNNTNVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNGNPTCNMTLQSLLDDSKADLTYNAMDIDLSHMVVDKTLPQIRVKPKSRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCVNENRSNHLDRSQLILSADRSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQGSANTMLNSGNTSTQPDIPLGIKYPPMTPMTSMANTAAITSSVTLAPAPLESTTSTSAPATKVETPMNELNVVVDTTSLFYAATAEQLPNASATTSVTTAATESNSFSIFPEQSFANSLTTQTATPQTISVDTNGAAATTSATTNQNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEDEEDEEDADNEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIHCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTAIEKINVHVDKNPIVMCAKCPFECEFESEMCKHLNAHHGINDGGSTHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDGNQITTATTISGTTTELDSNILAQHFSDSMGREGIGGGEGDGDGDGKCDKDTGCATENVATDTQTEAPQDTNDAPTSETTEPAAISNTEATPSITTTTVTSTEEGPATKTTSSSTLFPTPTPFDFDLDFMADGEHATDHKNNDSISIAPNPSHLLNGIDKLLTAALEPSPVKDLRTRLPRTPIFVCKQCNHTFDELGKLLQHELEQHSSGIVSPRLSYQHQCNICNTTYRTATLLNYHMKRHTPVKVSCKQCPKEFAHMSDLEQHLVTDHSVGAQTPLKCGMDGCTKTFNYKHHLKRHQTASHTAVQYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWEMTEQEIDQIYCINDIPTLTKYRERRSLKDEIDHSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00599838;
80% Identity: -