Dnig003862.1
Basic Information
- Insect
- Drosophila nigricruria
- Gene Symbol
- -
- Assembly
- GCA_037075265.1
- Location
- JBAMCI010000053.1:2601020-2606326[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0011 0.076 13.6 0.5 1 23 147 169 147 169 0.98 2 14 0.00014 0.01 16.4 1.3 1 23 394 416 394 416 0.98 3 14 1.7 1.2e+02 3.6 0.8 1 23 422 445 422 445 0.94 4 14 0.88 63 4.4 0.2 1 23 472 495 472 495 0.92 5 14 0.0012 0.09 13.4 1.9 3 23 768 788 767 788 0.92 6 14 0.05 3.6 8.4 1.4 1 23 794 817 794 817 0.98 7 14 3.5 2.5e+02 2.6 1.1 3 23 855 875 853 876 0.84 8 14 0.015 1.1 10.0 2.0 1 23 897 920 897 920 0.96 9 14 0.063 4.5 8.0 0.2 1 20 1140 1159 1140 1163 0.89 10 14 0.00031 0.022 15.3 4.2 1 23 1176 1198 1176 1198 0.98 11 14 1.3e-05 0.00096 19.6 0.2 2 23 1204 1226 1203 1226 0.97 12 14 0.001 0.071 13.7 3.8 2 23 1235 1259 1234 1259 0.90 13 14 0.048 3.4 8.4 0.6 1 23 1264 1286 1264 1286 0.97 14 14 0.0066 0.48 11.1 1.3 1 23 1292 1315 1292 1315 0.96
Sequence Information
- Coding Sequence
- ATGGCGCACAAGCGTGTAAAAACAGAGGCCATGGATatgaattacaaatttttgtgTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTACAAACTGGACTCGCTAATTGAGTGCGGCAGTGGCGAAAATGACGCGTCGTCTACGAAAATGCCACTGCTGCGTCTACTACTCTTCTGCATGCGCATCGAAAACCAGCCCGAGCTGCCCCAATACATATGCGTGGAGTGTACGAAAAGTTTGCAAATCGCCTACTATTTCATACAGAACGGCCAGCGAGCGCACGAGATACTGTGTCGGAAGCTGTGCCCCGGCAAGCTGAAGATCGCGTCAACGCGGTCGAATGGACAACAGGCAACGCAATGGCTCGAGTCGAAGGAGAGCGAGGATGCTACGCAGTCCAGGCTCTGGGAGCAGAAGCCAGCGAAGCCCGCGGCGCGACATGAATGTAAAGTGTGCGGCGCCATTATATACAATCGCATGGAGCTCAAGCAGCACATACGGATGCACACAGatgCCTCGATCCATCAGTGTAAATTGTGTAGCTTTGTCACGCTCAAGCATCGCCAGCTGCCAGAGCATTATCGCAAAGTACATGGACTGACGGCTGCCCAAATCGAGCATCAACTAAAGATCCGCAGATCCATgcaggcagcagcaaacgCAATAACAGCACCGACAAAATTAGCATTAGACACAGGAGCTGACGATGAGCAAGTAAAGGTTTGCACTCTGGAGGACATGGAATTGCTGATACCCACTGTGCTGACGCCAGAAGATTTTTCGCATCCGCAACTCGATGCGGATCAGCTGCGTGATATAGAGCAACAATTGGCGAACTCGATGCCCATTGTACAGTCCACCAGTCAGCCAGCGGAGCCAACGATAGGAAATGGCAATGGCACCAACGTAAGCATAGGTGCCGAGTTTCTGGTCATGCCCGATGGCTCGTTGCAGCAAGTGAATGATGGCGGTGTGGTGTTCGAGTACATTGACGATAGCAAAAGCGGCAATGTGACAAGTAATATGACATTGCAAAGTCTACTGGATGATTCCAAGGCCGATTTAACATACAATGCAATGGATATCGATTTGAGTCATATGGTTTTGGACCAAGCATTGCCACAGATAACTGTCAAGCCAAAGGCGCGCCCAGCACCAGCCTCCACTGGCGCCCTGAAACATAAATGCAAACTGTGTCCAAAAGCATTTCCTACGGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCCAAGTTCTATTGCGATCAGTGCTCCTATTATTCGCTACGCAGCGCCGATCTCATCCAGCACTATACGACGGAGCACAAGTCCTGCGTCAGCGAAAGTCGTTCGAATCATTTGGATAGATCACAATTGACTATGCCGGCGGACAGAAGTCGCATTTATTCCTGCGATATGTGTCTGTTCGAAGCGCCCACCAGTGGGCAATTGCGTGTACATTACAGCGATAAGCATCTAATAGTGCCCAGTGAGGTGCAACTGCGACCAAGTTGGACGCACGAACCGAAGCAAGGAAGCGCTTATACAATGCTAAACAGTGGCAGTGCTTCCAGTCAGCCCGATATTCCACTTGGAATCAAATATCCTCCCATGACATCAACGGCAGCCACTGCAGCAACTTCGACAACAACTGCGTTGGCGCCGCCGGCTCTGGCatcagcaacaccaacaacaacaacggtgGTAACGCCTATGAATGAAATTAATGTTGTGGTGGATGCCACATCATTGTTCTATGCAGCAACTGCAGAGCAGTTACCGAATactaatgctacaacatcagtaacaacggcaacaacagaaTCAAACACATTTTCTATGTTTCCCGAGCAATCTTTTGCAAACAGTctaacaacaccaacaacaacaccgaCAACAATTTCAGTAGACACAAACGGCGGGGCAACTACCACGTCGGCCACAGCAAATCCAAACACAAGCATATTTGGTGATATGCAGGATTTCATAGACAATACAGATGTGGCTGCCATTTGTACCATACCCGCAGACGATATGCCTGTCGTTGATGGAGATGAtattgttattgataataataatatcagcTTAGACTTTGATGCGGAAAACCTATTTGAGGATTTTGAAGATGTCGAGGTTGGCGAAGAGGATGAGGAAGATGAAGAGGATGCTGAAAATGaggatgaaaatgagaatAATGATGCGGCTACCGATCAAAATCTGTTGCTCACCAGTGACGATGACGACGTGGATGACTTTGACGACGAACAATCAAAGCATCTGCAGAAACCGTATTGCATATATTGTAACAAAAAGTTCACCAGCCAATATAAGTTCGAGAATCACATGTTTGTCCATCGCGGTTTGGCGCCGTATCGCTGTGAGCTGTGCACAAATCTGTACAATATGAAACGTCTGCTCATTCGGCATTACAAAACGGTGCATAAACGCATGCCCACTCGGGACATGGTGCAGGCCAAGGGCGACAAGGTGTCTGTGACCCGCACAGCCATTGAAAAGATAAATGTTAATGTTGACAAAAATCCCATGGTAATGTGTGCAAAGTGTCCATTTGAATGCGAACTGGAGGGTGAGATGCGCAAGCATTTAAATGCACATCATGGTATTAACGATGGtgGTTCTACGCATGCTAACGAGGTGTTTATCATACGCAAACTGCCCTTTGACTGTCCACGCTGTATTCGGTCCTTTGCGGCTAAACACACGCTTACACGACACTTGCAACGTAGTCATTTAGTGGATACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCTGCGGCCACCACGACGACATCGACGGCAACAACCACATTGCCGCAGAATGCAAGTGATggcaataaaacaacaacagcaacaacaacatccgGAGCAACAACTGAACTGGATTCGAACATATTGGCACAGCATTTCGCAGACTCTGTGGATGGTGATGGCGTTGGAGAAGGCGATGGCGGTGGCAATGGAAAATGCGACACGGACACAGCATGCACAACGGAAAATGCAAGCACAGATATACACACCGAAGCACCAGAAGAGACAAACGATGCAGCAACAACTGAAACTACAGAACCTGCAACAATACCAAACACTGATGCCACAGAAGCTGAAACAccatcaataacaacaacggcaacggaaGAAggaccagcaacaacaacaacagcggctgGTTCAGCACTCTTTCCAACGCCCACGCCATTTGACTTTGATCTTGATTTTATGGGCGATGGTGAGCATGCCACGACCATTAAGAACAACGACAGCTTCAACGTTACGCCGAATGCCAGTCATCTGTTGAATGGAACCGATAAGCTATTGACTGCTGCGTTGGAGCCATCGCCAGTTAAAGATCTTCGCACGCGCCTGCCGCGTACACCGATATTTGTGTGCAAGCAATGTAATCTGACGTTCGATGAGCTTGGCAAGCTGCTGCAGCACGAAGTGGAGCAACATTCCAGCGACGTTGTATCGCCGCGCAACAGTTACCAGCATCAGTGCAAGATCTGCAATACAACGTACCGCACCGTAACGCTACTTAACTATCATATGAAACGGCATACGCCAGTGAAAGTTTCATGCAAGCAGTGCCCCAAAGAGTTTGCAAACATTTCCGATTTGGAGCAGCATTTACGGACGGAGCATAGCGTCGGAGCACAGACGCCGCTCAAATGCGGCGTAGATGGCTGCACTAAGACATTTAACTACAAACATCATTTGAAACGGCATCAGACAGCCTCTCACACGCGCGTACAGTATATCTGTCCGGAATGCGGACGCGATATGCTTACTAGTCTGCATCTCAGGAATCATATGTCCAGCCACAAGAGCACACACTCTTATAAGTGTCCCAAATGTGTGCGCACCTATATGAGACGCAATCCctttcGCAGGCATGCGCTACGTGAGCACAAGTGGGAGCTGACCGACCAGGAGATTGatcaaatttattgcattAATGAGATACCGACTTTGAGCAAATTTCGTGGACGTAGATCGTTGAAGGCTGACATCGATCAGTCTGATTAG
- Protein Sequence
- MAHKRVKTEAMDMNYKFLCRCCLKSEAEFYKLDSLIECGSGENDASSTKMPLLRLLLFCMRIENQPELPQYICVECTKSLQIAYYFIQNGQRAHEILCRKLCPGKLKIASTRSNGQQATQWLESKESEDATQSRLWEQKPAKPAARHECKVCGAIIYNRMELKQHIRMHTDASIHQCKLCSFVTLKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQAAANAITAPTKLALDTGADDEQVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEQQLANSMPIVQSTSQPAEPTIGNGNGTNVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKSGNVTSNMTLQSLLDDSKADLTYNAMDIDLSHMVLDQALPQITVKPKARPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCVSESRSNHLDRSQLTMPADRSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQGSAYTMLNSGSASSQPDIPLGIKYPPMTSTAATAATSTTTALAPPALASATPTTTTVVTPMNEINVVVDATSLFYAATAEQLPNTNATTSVTTATTESNTFSMFPEQSFANSLTTPTTTPTTISVDTNGGATTTSATANPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDEEDEEDAENEDENENNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVTRTAIEKINVNVDKNPMVMCAKCPFECELEGEMRKHLNAHHGINDGGSTHANEVFIIRKLPFDCPRCIRSFAAKHTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPQNASDGNKTTTATTTSGATTELDSNILAQHFADSVDGDGVGEGDGGGNGKCDTDTACTTENASTDIHTEAPEETNDAATTETTEPATIPNTDATEAETPSITTTATEEGPATTTTAAGSALFPTPTPFDFDLDFMGDGEHATTIKNNDSFNVTPNASHLLNGTDKLLTAALEPSPVKDLRTRLPRTPIFVCKQCNLTFDELGKLLQHEVEQHSSDVVSPRNSYQHQCKICNTTYRTVTLLNYHMKRHTPVKVSCKQCPKEFANISDLEQHLRTEHSVGAQTPLKCGVDGCTKTFNYKHHLKRHQTASHTRVQYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTDQEIDQIYCINEIPTLSKFRGRRSLKADIDQSD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00512961;
- 90% Identity
- -
- 80% Identity
- -