Basic Information

Insect: Drosophila mojavensis
Gene Symbol: -
Assembly: GCA_018153725.1
Location: JAECYD010000080.1:6885313-6890795[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.5e-05 0.0074 16.7 1.2 1 23 147 169 147 169 0.98

2 14 0.00013 0.0099 16.3 1.7 1 23 395 417 395 417 0.98

3 14 1.5 1.1e+02 3.5 0.8 1 23 423 446 423 446 0.94

4 14 0.76 59 4.4 0.2 1 23 473 496 473 496 0.92

5 14 0.0041 0.32 11.6 3.9 3 23 768 788 767 788 0.92

6 14 0.043 3.4 8.3 1.4 1 23 794 817 794 817 0.98

7 14 0.62 48 4.7 1.3 3 23 855 875 853 876 0.91

8 14 0.011 0.87 10.2 0.5 1 23 897 920 897 920 0.97

9 14 0.034 2.7 8.7 1.1 1 23 1147 1170 1147 1170 0.91

10 14 0.00027 0.021 15.3 4.2 1 23 1183 1205 1183 1205 0.98

11 14 0.00024 0.019 15.4 0.1 2 23 1211 1233 1210 1233 0.93

12 14 0.0011 0.089 13.3 4.2 2 23 1242 1266 1241 1266 0.89

13 14 0.041 3.2 8.4 0.6 1 23 1271 1293 1271 1293 0.97

14 14 0.0057 0.45 11.1 1.3 1 23 1299 1322 1299 1322 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.5e-05	0.0074	16.7	1.2	1	23	147	169	147	169	0.98
2	14	0.00013	0.0099	16.3	1.7	1	23	395	417	395	417	0.98
3	14	1.5	1.1e+02	3.5	0.8	1	23	423	446	423	446	0.94
4	14	0.76	59	4.4	0.2	1	23	473	496	473	496	0.92
5	14	0.0041	0.32	11.6	3.9	3	23	768	788	767	788	0.92
6	14	0.043	3.4	8.3	1.4	1	23	794	817	794	817	0.98
7	14	0.62	48	4.7	1.3	3	23	855	875	853	876	0.91
8	14	0.011	0.87	10.2	0.5	1	23	897	920	897	920	0.97
9	14	0.034	2.7	8.7	1.1	1	23	1147	1170	1147	1170	0.91
10	14	0.00027	0.021	15.3	4.2	1	23	1183	1205	1183	1205	0.98
11	14	0.00024	0.019	15.4	0.1	2	23	1211	1233	1210	1233	0.93
12	14	0.0011	0.089	13.3	4.2	2	23	1242	1266	1241	1266	0.89
13	14	0.041	3.2	8.4	0.6	1	23	1271	1293	1271	1293	0.97
14	14	0.0057	0.45	11.1	1.3	1	23	1299	1322	1299	1322	0.96

Sequence Information

Coding Sequence: ATGGCGCACAAGCGATTAAAAACAGAGGGCATGGAAACGAATTACAAATTTTCGTGTCGCTGTTGCCTCAAATCCGAAGCGGAATTCTACAAACTAGACTCGCTAATCGAGTGCGGCAGTGGCGAAAATGACGCGTCCTCTACAAAAATACCCCTACTGCGTTTACTATTATTCTGCATGCGCATCGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTGGAGTGTAGTAAGAGTTTGCAAATCTCCTACTATTTCATACAGAACGGACTGAGAGCACATGAAATACTCTGTCGGAAACTGTGCCCCGGCAAGCTAAAGCTAAACTCGACGCGTTCCAATGGTCAACAGCCAACACAAAGGCTCGAGTCCAACGAGAGCGAGGATGCGTCGCTGTCCAGACTCTGGGATCAAAAGCCACAAAAGTCTATGACGCGGCACGAATGTAAAGTATGCGGTACCATGGTATACAATCGCATGGAGCTCAAGCAGCACATACGCATGCACGCAGATGCATCGAGTCATCAGTGCAAATTGTGCAGCTTTGTCACGTACAAGCACCGCCAGCTGCCGGAACATTATCGCAAAGTACATGGCCTGACGGCTGCCCAAATTGAGCATCAGCTCAAGATCCGCAGATCCATGCAGGCAGCTGCAAACGCAATAAAATCACCGCCAAAACTACCAATAGAACCAGGAGATGGCGAGGAGCAAGTGAAGGTCTGCACTCTGGAGGATATGGAACTGTTGATTCCCACTGTGCTGACGCCAGAAGATTTTTCGCATCCTCAACTTGATGCGGATCAGCTGCGTGATATAGAGCAACAATTGGCGAACTCGTTGCCCGTCGTACAGTCCACCACCCAGGCGGCTGAGCCAACAATAGGGTGTGGCAATAGCGGCAATGTAAGCATAGGTGCCGAGTTTCTGGTCATGCCCGATGGCTCCTTGCAGCAAGTGAATGATGGCGGTGTGGTATTCGAGTACATTGACGACAGCAAAAACGGCAATGGGGCGGCACCTAACATGACATTACAGAGCCTACTGGATGATTCCAAGCCTGACTTGACATATAGTGCAATGGACATCGACTTAAGTCATATGTCTGTGGGCAATGTATTGCCACAGATAAAAGTCAAGCCGAAGGCACGACCAGCTCCCGCGTCTACTGGCGCACTGAAACATAAATGCAAGCTGTGTCCAAAAGCATTTCCCACGATGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCAAAATTCTATTGCGATCAGTGCTCCTATTATTCGCTACGCAGCGCCGATCTCATCCAGCATTATACGACGGAACACAAGTCCAGCGTTGGCGATAATCGTTCGAATAATTTGGATAGATCCCAATTACTTTTGCCGGCAGATAAAAGTCGCATTTATTCCTGCGATATGTGTCTGTTCGAGGCGCCAACCAGTGGGCAACTGCGTGTGCACTACAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAACTGCGTCCCAGTTGGACGCATGAGCCGAAGCAGGGGGGCGCTAATACAATGGTAAACAGTGGTAATGCTTCCAGCCAGCCTGATATTCCAGTTGCCATAAAATATCCTTCCATGACGTCAGCGGCATCCACTGCATCAACTACATTAACAACTCCGTGTGCGCCACAAATTATGGAATCAACAACGACAACAACAACTGTGGGAACAACTATGAATGAGCTAAATGTTGTGGTGGATACCACACCATTGTTCTATGCAGCAACTGCAGAGCAGTTACCGAATACTGATGCGACAACATCAGTAACAACGGCAGCTACAGAGTCAAATACATTTTCAATGTTCCCAGAGCAATCGTTTGCTAACAGCCTGACAACACCAACAAAAACACCGCCAACAATTGCAGCAGATGCAAACGGTGTGGGAATCGCCACATCGGCCACAACAAATCCAAACACAAGTATATTTGGTGATATGCAAGATTTTATAGATAATACCGATGTGGCTGCCATTTGTACCATACCCGCCGATGATATGCCTGTCGTTGATGGAGATGATATTGTTATTGATAACAATAATATCAGTTTGGACTTTGATGCGGAAAATCTATTCGAGGATTTTGAAGATGTCGAGGTTGGCGAAGAGGATGAAGAAGACGAGGAGGATGCTGAAAATGAGGATGAAAATGACAACAACGATGCGGCTGCTGATCAGAATCTGTTGCTTACCAGTGACGATGACGATGTTGACGACTTCGATGATGAACAATCGAAGCATCTGCAGAAACCGTATTGCATCCATTGTAATAAGAAGTTCACCAGCCAATATAAGTTCGAGAATCACATGTTCGTGCACCGCGGTTTGGCGCCGTATCGCTGTGAGCTGTGCACCAATTTGTATAATATGAAACGACTGCTCATTCGACATTATAAGACGGTGCATAAGCGCATGCCCACACGGGACATGGTGCAGGCCAAGGGCGACAAGGTTTCTGTGGCTCGTACAGCCATTGAGAAGATAAATGTTCACGTTGACAAAAATCCTATGGTAATGTGTGCTAAATGTCCATTTGAATGCGAACAGGAGGGTGAAATGCGCAAACATTTAAGTGCGCATCATGGCATTAATGATGGTGGGTCTACGCATGCCAATGAGGTGTTTATCATACGCAAATTGCCTTATGACTGTCCACGCTGTATTCGGTCCTTTGCGGCTAAGCGCACGCTTATAAGACATCTGCAGCGTAGCCATTTAGTGGACACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCGGCAACCACGACCACATCGACGGCAACAACTACATTGCCGCTCAACGCCAGTGATGGCAATATATCAACAACAGCAACAACAACATTGGGGACAACAACTCCACTAGATTCGAACATATTGGGGCAGCATTTCTCGGACTCTGTGGATGGTGATGGCAATGGCAGCGGTGGAGGCGATGGCAACGGCGATGGCGATGGCAATGGAAAATGCGACAGGGACACAGGATTCACAACGGAAAATGTAACCACAAATACACAAACCGAAGCACCAAAAGACACAATCGATGCAACCACAACTGAACCTACTGAACCTACTGGATCAACAGAACCAGCAAACACTAACACCACAGAAGCAGAAACACCATCAATAACAACAACAAGTGAAGAAGGACCAGCAACAACAGCAACTGCTGGCTCAGCACTCTTTCCAACGCCCACTCCATTTGACTTCGATCTTGATTTTATAGGCGATGGAGAGCATGCCACGACCATTAAGAACAGCGACAGCTTCAGCATTGAACCCAATCACAGTCACCTATTGAATGGAACCGATAAGCTACTGACTGCTGCGTTAGAGCCATCGCCAGTTAAAGACCTGCGCTCGCGCCTACCCCGTACCCCCATCTTTGTGTGCAAGCAATGTAATCACACCTTCGATGAGCTTGGCAAGCTGTTGCAGCACGAGCTGGAGCAACATTCCAGCGGCATTATATCGCCGCGCAATAGTTACCAGCATCAGTGCAAGATCTGCAATACAACATACCGCACTGTAACGCTACTTAACTATCACATGAAACGGCATACGACAGTAAAAGTTCCATGCAAACAGTGTCCTAAAGAGTTTGCAAACACATCCGAATTGGAGTCGCATTTACTGGCGGAGCATAGCGTCGGAGCACAGACGCCTCTCAAATGCGGCATTAATGGCTGCACTAAGACATTTAACTACAAGCATCATCTGAAACGACATCAGACTGCCTCCCACACGGCCGTACAGTATATTTGCCCGGAATGCGGACGCGATATGCTTACTAGTCTGCATCTCAGGAATCATATGTCCAGCCATAAGAGCACACACTCTTACAAGTGTCCCAAATGTGTGCGCACCTATATGAGGCGCAATCCTTTTCGCAGACATGCGCTACGTGAGCACAAGTGGGAGCTGACCGAGCAGGAGATTGATCAAATTTACTGTATTAATGATATACCGACTTTGGGTAAATTTCGTGAGCGTAGATCGTTGAAGGTTGAGATCGACCAGTCCGACTAG
Protein Sequence: MAHKRLKTEGMETNYKFSCRCCLKSEAEFYKLDSLIECGSGENDASSTKIPLLRLLLFCMRIENQPELPQYICVECSKSLQISYYFIQNGLRAHEILCRKLCPGKLKLNSTRSNGQQPTQRLESNESEDASLSRLWDQKPQKSMTRHECKVCGTMVYNRMELKQHIRMHADASSHQCKLCSFVTYKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQAAANAIKSPPKLPIEPGDGEEQVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEQQLANSLPVVQSTTQAAEPTIGCGNSGNVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNGNGAAPNMTLQSLLDDSKPDLTYSAMDIDLSHMSVGNVLPQIKVKPKARPAPASTGALKHKCKLCPKAFPTMARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSSVGDNRSNNLDRSQLLLPADKSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQGGANTMVNSGNASSQPDIPVAIKYPSMTSAASTASTTLTTPCAPQIMESTTTTTTVGTTMNELNVVVDTTPLFYAATAEQLPNTDATTSVTTAATESNTFSMFPEQSFANSLTTPTKTPPTIAADANGVGIATSATTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDEEDEEDAENEDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIHCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTAIEKINVHVDKNPMVMCAKCPFECEQEGEMRKHLSAHHGINDGGSTHANEVFIIRKLPYDCPRCIRSFAAKRTLIRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDGNISTTATTTLGTTTPLDSNILGQHFSDSVDGDGNGSGGGDGNGDGDGNGKCDRDTGFTTENVTTNTQTEAPKDTIDATTTEPTEPTGSTEPANTNTTEAETPSITTTSEEGPATTATAGSALFPTPTPFDFDLDFIGDGEHATTIKNSDSFSIEPNHSHLLNGTDKLLTAALEPSPVKDLRSRLPRTPIFVCKQCNHTFDELGKLLQHELEQHSSGIISPRNSYQHQCKICNTTYRTVTLLNYHMKRHTTVKVPCKQCPKEFANTSELESHLLAEHSVGAQTPLKCGINGCTKTFNYKHHLKRHQTASHTAVQYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTEQEIDQIYCINDIPTLGKFRERRSLKVEIDQSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00473325;
80% Identity: -