Basic Information

Insect: Drosophila meridionalis
Gene Symbol: -
Assembly: GCA_035045145.1
Location: JAWNPG010000003.1:3122268-3127811[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00029 0.021 15.4 0.5 1 23 146 168 146 168 0.98

2 14 0.00014 0.01 16.4 1.3 1 23 393 415 393 415 0.98

3 14 1.7 1.2e+02 3.6 0.8 1 23 421 444 421 444 0.94

4 14 0.88 62 4.4 0.2 1 23 471 494 471 494 0.92

5 14 0.0012 0.088 13.4 1.9 3 23 768 788 767 788 0.92

6 14 0.05 3.5 8.4 1.4 1 23 794 817 794 817 0.98

7 14 1.3 94 3.9 0.9 3 23 855 875 853 876 0.89

8 14 0.0087 0.61 10.7 0.8 1 23 897 920 897 920 0.97

9 14 0.018 1.3 9.8 1.2 1 23 1141 1164 1141 1164 0.93

10 14 0.00031 0.022 15.3 4.2 1 23 1177 1199 1177 1199 0.98

11 14 0.00064 0.045 14.3 0.1 3 23 1206 1227 1205 1227 0.93

12 14 0.0015 0.1 13.2 3.8 2 23 1236 1260 1235 1260 0.88

13 14 0.048 3.4 8.4 0.6 1 23 1265 1287 1265 1287 0.97

14 14 0.1 7.3 7.3 1.5 1 23 1293 1316 1293 1316 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00029	0.021	15.4	0.5	1	23	146	168	146	168	0.98
2	14	0.00014	0.01	16.4	1.3	1	23	393	415	393	415	0.98
3	14	1.7	1.2e+02	3.6	0.8	1	23	421	444	421	444	0.94
4	14	0.88	62	4.4	0.2	1	23	471	494	471	494	0.92
5	14	0.0012	0.088	13.4	1.9	3	23	768	788	767	788	0.92
6	14	0.05	3.5	8.4	1.4	1	23	794	817	794	817	0.98
7	14	1.3	94	3.9	0.9	3	23	855	875	853	876	0.89
8	14	0.0087	0.61	10.7	0.8	1	23	897	920	897	920	0.97
9	14	0.018	1.3	9.8	1.2	1	23	1141	1164	1141	1164	0.93
10	14	0.00031	0.022	15.3	4.2	1	23	1177	1199	1177	1199	0.98
11	14	0.00064	0.045	14.3	0.1	3	23	1206	1227	1205	1227	0.93
12	14	0.0015	0.1	13.2	3.8	2	23	1236	1260	1235	1260	0.88
13	14	0.048	3.4	8.4	0.6	1	23	1265	1287	1265	1287	0.97
14	14	0.1	7.3	7.3	1.5	1	23	1293	1316	1293	1316	0.95

Sequence Information

Coding Sequence: ATGGCAAACAAGCGAGTAAAAACAGAGGACATGGAAACGAATTACAAATTTTCGTGTCGCTGTTGCCTTAAGTCCGAGGCAGAGTTCTACAAACTGGACTCGCTAATCGAGTGCGCCAGTGGCGAAAGTGACGCGTCCTCTACGAAAATACCCCTTCTACGTTTACTACTATACTGCATGCGCATCGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTCGAGTGTAGTAAAAGTTTGCAAATCGCTTACTATTTCATACAGAACAGTCTGCGGGCACACGAAATACTCTGTCGGAAACTGTGCCCCGGCAAGCTAACGAACTCGACGCGTTCCAATGGCCAACAGACAACGCAATGGCTCGAGTCGAACGAGAGTGAGAATGCGATGCAGCCCAGACTCTGGGATCAAAAGCCACAGAAGCCAGCGGCGCGACACGAATGCAATGAGTGCGGTGCCATTCTATACACTCGCATGGAGCTCAAGCAGCACATACGCATGCACGCAGATGCTTTGAGCCATAAGTGCAAATTGTGCAGCTTTGTCACGTTGAAGCATCGGCAGCTACCGGATCATTATCGCAAAGTGCACGGCTTGACGGCTGCCCAAATCGATCATCAACTTAAGATCCGGAGATCCATGCAGGCAGCCGCAAACGCCATAACCGTACCCAGAAAAATACCCCTAGAAAGGGGAGCTGACGATGAGCAAGTGAAGGTTTGCACTCTGGAGGACATGGAACTTCTGATACCCACGGTGCTGACTCCAGAGGATTTCTCGCATCCTCAACTTGACGTGGATCAGTTGCGTGGCATAGAGCAACAATTGGCAAACTCTTTGCCCATTGTACAGTCCTCCAGCCAGCCGGCGGAGCCAACGATAAGGAGTGGCAATGGCGCCAATGTCAGCATAGGTGCCGAGTTTCTGGTCATGCCCGATGGTTCCTTGCAGCAAGTGAATGATGGCGGAGTGGTGTTCGAGTACATTGATGACAGCAAAACCGGAAATCCGACAAGTAATGTGACTTTGCAGAGTCTATTGGACGATTCCAAGGCCGATTTACCATTTAATGCAATGGACATCGACTTAAGTCATATGGTCGTTGACCATGCATTGCCACAGATAAAAGTCAAGCCAAAGGCGCGTCCAGCACCCGCCTCCACTGGCGCCTTGAAACATAAATGCAAACTGTGTCCAAAAGCATTTCCCACAGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTGCCAAAATTCTACTGCGATCAGTGCTCCTATTACTCGCTACGCAGCGCCGATCTCATCCAACATTATACGACGGAGCACAAGTCCAGCGTTGGCGAGGGTCGTTCGAATCATTTGGATAGGTCACACTTAACTGTGCCGGCGGATAGAAGTCGCATTTACTCCTGCGATATGTGTCTCTTCGAAGCGCCAACCAGTGGACAATTGCGTGTGCACTACAGCGATAAGCATCTGATAGTGCCCAGTGAGGTTCAACTGCGTCCCAGTTGGACGCATGAGCCAAAGCAGAGTAGCGCCAATACAATGATAAACAGTGGCAATAGTTCCAGTCAGCCCGATATTCCACTCGGCATTAAATatCCTCCCATGACGTCAACAGCAAccgctgcagcaacaacatcaacaactgCGATGCCGCCGCCAACTCTGGAATCAACAGCAATAACATCAAGAACAACGGTGGACACACCTATGAACGAGCTTAATGTCGTGGTAGATACGACATCATTGTTCTatgcagcaactgcagagCAGTTACCGAATCCCACTGCTGAAACAGTAGCTACGGCAGCACCAGAACCAAATACGTTTTCAATGTTTCCCGAGCAATCATTTGCGAATAGtctaacaacagcaacaacatcgacaGTAGTTCCACAAACAGTAGACACAAACGGCGTGTCAACTACCCCATCGGCCTCGACAAATCCCAACACAAGCATATTTGGCGATATGCAGGATTTTATAGATAATACCGATGTGGCTGCCATTTGCACGATTCCCGCTGATGATATGCCTGTAGTTGATGGGGATGATATTGTTATTGACAACAATAATATCAGTTTGGATTTCGATGCGGAAAATCTGTTTGAGGAGTTTGAAGATGTCGAGGTTGGCGAAGAGGATGAAGACGATGAAGAGGATGCTGAAAATGaggatgaaaatgaaaataacgaTGCGGCTGCCGATCAAAATCTGCTGCTCACCAGTGACGATGACGATGTGGATGACTTCGATGATGAGCAATCTAAGCATCTGCAGAAACCGTATTGCATCTATTGTAATAAAAAGTTCACCAGCCAATATAAGTTCGAGAATCACATGTTTGTGCATCGCGGGCTGGCGCCGTATCGCTGTGAGCTGTGCACCAATCTGTACAACATGAAACGTCTGCTCATCCGACATTATAAGACGGTGCACAAACGCATGCCCACACGGGACATGGTGCAGGCCAAGGGCGACAAGGTGTCTGTGGCCCGCACAGCAATTGAGAAGATAAATGTTCATGTTGACAAAAATCCTATGGTAATGTGTGCTAAATGTCCATATGAATGCGAACTGGAGGCTGAAATGCGCAAACACTTGAATGCGCATCATGGCATTAACGATGGtgGCTCCACGCATGCCAATGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCGCGCTGTATTCGGTCCTTTGCGGCTAAACGCACGCTTACACGACATTTACAGCGTAGCCATTTAGTGGACACAATTATTGAGATGCAGGCGCCTCAATTGACAACCAGTTCGGCGGCCACCACGACCACATCGACGGCAACGACCACATTGCCGCTGAACGCCAGTGATGAAAataagacaacaacagcaataacaacatccGGGGCAACTACTCAGCTGGACTCGAACGTATTGGCGCAACATTTCGGAGACTCTGGGGACGGTATTGGCAATGCAGAAGgcaatggcgatggcgatggtcATGGCGATGGCAATGGAAAATGCGACATGGACTCAGGATGCACTCATAGATCACAAGACACAAAcaatgcagcaacaactgaaGCTACAGAACCATCAGCAATACCAAACACTGAAGTCGCAGAAGCTGAAAAACTctcagtaacaacaacagcaacaacaacaacaactgaagaagggccagcaacaacaacaaccacaacagctGGCTCAACACTCTTTCCAACGACCACGCCATTTGACTTTGATCTTGATTTTATGGGCGATGGTGAGCATGCCACGACCCTTAAAAACAACGACAGCTTCAACACTGCACCGAATCCCAGTCATCTGTTGAATGGAGCCGATAAGCTACTGACTGATGCGTTGGAGCCATCGCCTGTAAAAGATCTGCGCACGCGCCTACCCCGCACACCCATATTTGTGTGCAAGCAATGTAATCATACCTTCGATGAGCTTGGGAAGCTGATGCAACATGAAATGGAGCAACATTCCAGCGGCACTGTATCGCCGCGCGGCAGCTACCAGCATCAGTGCAAGATCTGTAACACAACGTACCGTACCGTAACGCTACTTAACTATCACATGAAACGGCATATGCCAGCAAAAGTTGCATGCAAGCAGTGCCCGAAAGAGTTCGCAAATATATCCGATTTGGAGCAGCATTTGCTGGCGGAGCACAGCGCCGGAACACAGATGCCTCTGACATGCGGCATGGATGGCTGCACTAAGACATTTAACTACAAACATCATCTTAAACGGCATCAGACAGCGTCCCACACGGCCGTGCAGTATATCTGTCCGGAATGCGGACGCGATATGCTTACTAGTCTGCATCTCAGGAATCATATGTCCAGCCACAAGAGTACGCACTCTTATAAGTGTCCCAAATGTGTGCGCACTTATCTGAGACGCAAGCCcTTTCGCAGACATGCGCTACGTGAGCACAAGTGGGAGCTGACCGAACAGGAGATTGatcaaatttattgcattaatGATGTACCGACCTTGGGTAAATTTCGCGATAGTAGATCGTCGAGGGTTAAGATCGAACAGTCAGATTAG
Protein Sequence: MANKRVKTEDMETNYKFSCRCCLKSEAEFYKLDSLIECASGESDASSTKIPLLRLLLYCMRIENQPELPQYICVECSKSLQIAYYFIQNSLRAHEILCRKLCPGKLTNSTRSNGQQTTQWLESNESENAMQPRLWDQKPQKPAARHECNECGAILYTRMELKQHIRMHADALSHKCKLCSFVTLKHRQLPDHYRKVHGLTAAQIDHQLKIRRSMQAAANAITVPRKIPLERGADDEQVKVCTLEDMELLIPTVLTPEDFSHPQLDVDQLRGIEQQLANSLPIVQSSSQPAEPTIRSGNGANVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKTGNPTSNVTLQSLLDDSKADLPFNAMDIDLSHMVVDHALPQIKVKPKARPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSSVGEGRSNHLDRSHLTVPADRSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQSSANTMINSGNSSSQPDIPLGIKYPPMTSTATAAATTSTTAMPPPTLESTAITSRTTVDTPMNELNVVVDTTSLFYAATAEQLPNPTAETVATAAPEPNTFSMFPEQSFANSLTTATTSTVVPQTVDTNGVSTTPSASTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEEFEDVEVGEEDEDDEEDAENEDENENNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTAIEKINVHVDKNPMVMCAKCPYECELEAEMRKHLNAHHGINDGGSTHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDENKTTTAITTSGATTQLDSNVLAQHFGDSGDGIGNAEGNGDGDGHGDGNGKCDMDSGCTHRSQDTNNAATTEATEPSAIPNTEVAEAEKLSVTTTATTTTTEEGPATTTTTTAGSTLFPTTTPFDFDLDFMGDGEHATTLKNNDSFNTAPNPSHLLNGADKLLTDALEPSPVKDLRTRLPRTPIFVCKQCNHTFDELGKLMQHEMEQHSSGTVSPRGSYQHQCKICNTTYRTVTLLNYHMKRHMPAKVACKQCPKEFANISDLEQHLLAEHSAGTQMPLTCGMDGCTKTFNYKHHLKRHQTASHTAVQYICPECGRDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYLRRKPFRRHALREHKWELTEQEIDQIYCINDVPTLGKFRDSRSSRVKIEQSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00544754;
80% Identity: -