Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:2646703-2652718[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00022 0.012 15.5 0.4 1 23 146 168 146 168 0.98

2 14 0.00012 0.0067 16.4 1.3 1 23 393 415 393 415 0.98

3 14 3.2 1.8e+02 2.4 0.8 1 23 421 444 421 444 0.91

4 14 0.73 41 4.4 0.2 1 23 471 494 471 494 0.92

5 14 0.001 0.059 13.4 1.9 3 23 762 782 761 782 0.92

6 14 0.041 2.4 8.4 1.4 1 23 788 811 788 811 0.98

7 14 2.9 1.6e+02 2.6 1.3 2 23 848 869 847 870 0.85

8 14 0.0072 0.41 10.8 0.8 1 23 891 914 891 914 0.97

9 14 0.014 0.8 9.8 0.3 1 23 1133 1156 1133 1156 0.91

10 14 0.00026 0.015 15.3 4.2 1 23 1169 1191 1169 1191 0.98

11 14 0.00012 0.0066 16.4 0.1 2 23 1197 1219 1196 1219 0.95

12 14 0.00082 0.047 13.7 3.8 2 23 1228 1252 1227 1252 0.90

13 14 0.44 25 5.1 1.9 1 23 1257 1279 1257 1279 0.95

14 14 0.0055 0.31 11.1 1.3 1 23 1285 1308 1285 1308 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00022	0.012	15.5	0.4	1	23	146	168	146	168	0.98
2	14	0.00012	0.0067	16.4	1.3	1	23	393	415	393	415	0.98
3	14	3.2	1.8e+02	2.4	0.8	1	23	421	444	421	444	0.91
4	14	0.73	41	4.4	0.2	1	23	471	494	471	494	0.92
5	14	0.001	0.059	13.4	1.9	3	23	762	782	761	782	0.92
6	14	0.041	2.4	8.4	1.4	1	23	788	811	788	811	0.98
7	14	2.9	1.6e+02	2.6	1.3	2	23	848	869	847	870	0.85
8	14	0.0072	0.41	10.8	0.8	1	23	891	914	891	914	0.97
9	14	0.014	0.8	9.8	0.3	1	23	1133	1156	1133	1156	0.91
10	14	0.00026	0.015	15.3	4.2	1	23	1169	1191	1169	1191	0.98
11	14	0.00012	0.0066	16.4	0.1	2	23	1197	1219	1196	1219	0.95
12	14	0.00082	0.047	13.7	3.8	2	23	1228	1252	1227	1252	0.90
13	14	0.44	25	5.1	1.9	1	23	1257	1279	1257	1279	0.95
14	14	0.0055	0.31	11.1	1.3	1	23	1285	1308	1285	1308	0.96

Sequence Information

Coding Sequence: ATGGCCCACAAGCGAGTAAAAACACAGGACATGgcaataaattacaaatttttgtgtCGCTGTTGCCTCAAATCTGAGGCAGAATTCTATAAACTGGACTCACTCATCGAGTGCGGCGGTGGCGAAAGTGACGCGTCTTCTACAAAAATACCCCTACTACGTTTACTATTATTCTGCATGCGTATCGAAAATCAGCCCGAGTTGCCACAATATATATGCGTGGAGTGCAGTAAAAGTTTGCAAATTGCCTACTATTTCATTCAAAACGGCCTGCGAGCACATGAAATACTCTGTCGTAAATTGTGTCCCGGGAAGCTGAAGAATCCAACGCGTTTTAATGGCCAACAGTCAGCGCAATGGCTGGAGTTGAACGAGAGTGAGGATGCGACGCAGTCCAGGCCCTGGGAGCAAAAGTCACAAAAGCCTGTTGTGCGACATGAATGTAAAGTATGCGGTGCCATTATATCCAATCGTATGGAGCTCAAGCAGCACATACGTATGCACGCAGATCAATCGAGCCATCAGTGCAAATTGTGCAGTTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTACCGCAAAGTACACGGCCTGACGGCTGCCCAAATCGAGCATCAACTTAAGATCCGAAGATCCATGCAGTCAGCTGTAAACGCAATAATAGCGCCGAAACAAATACCAATAGATACACCAGCTGAGGATGAGCAAGTGAAGGTTTGCACTCTGGAGGATATGGAACTGCTGATACCCACTGTTTTGACACCAGAAGACTTTTCGCATCCTCAACTTGATGCGGATCAGCTACGTGATATAGAGCAACAATTGGCAAACTCGTTGCCAATTATACAGTCCACCAATCAGACGGCCGAGCCAACGATAGGGACTGCCAATAGCGCCAATGTCAGCATCGGTGCCGAATTTTTGGTCATGCCCGATGGCTCCCTACAGCAAGTGAATGATGGCGGTGTGGTATTCGAATACATTGACGATAGTAAAAACGCCAATGCAACAAGTAATGTAACATTGCACAATCTATTTCATGATTCCAAGGACGATTTAACATATAATGAAATGGATATCGATTTAAGCCATATGGTTGTGGATAATGTGTTGCCACAGATAACAGTCAAGCCAAAGCCGCGCCCAGCACCCGCATCCACTGGTGCCCTGAAACATAAATGCAAACTGTGTCCCAAAGCATTTCCCACGGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTACCTAAATTCTATTGCGATCAGTGCTCCTTTTATTCACTACGCAGCGCAGATCTCATTCAGCATTATACGACGGAGCACAAGTCCTGTGTTAACGAGAGTCGTTCGAATCATTTGGATAGATCACAATTGAGTTTTCCGGCGGATAGAAGTCGCATTTATTCCTGCGATATGTGTTTGTTCGAAGCACCCACCAGTGGACAATTGCGTGTGCACTATAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAACTGCGGCCTAGTTGGACGCATGAGCCAAAGCAGAGGAATACTGATACAATGCTAAGCAGTGGAAATGCATCCACTCAGCCCGATATTCCATTGGGTATCAAATatCCTCCCATAACGTCAACggcaacaactgctgcaactTCATCAACGACTGGGTTGGCGCAGCCACccctggcaacaacaacaacaaccacggTGGTAACGCCTATGAATGACATTAATGTGGTGGTGGATACCACATCATTGTTCTATGCAGCGACTGCAGAGCAGTTACCAAATAATAATGCTACAACAGCGACAACTACAGATTCAAacacattttcaatatttcccGAGCAATCTTTTGCCAACAGTttaacaacaccaacagcaacccCGACCACAATTTCAGTGGACACAAACGGTGTGGTAACAACCACATCATCGACAACAAATCCAAACACGAGCATATTTGGGGACATGCAGGATTTTATAGATAATACCGATGTCGCTGCTATTTGTACCATACCCGCCGATGATATGCCTGTCGTGGATGGAGATgatattgttattgataataataatatcagtTTAGATTTTGACGCGGAAAATCTATTTGAGGACTTTGAAGATGTCGAGGTTGGCGAAGAGgatgaagaagatgaagaagatgCTGAAAACGAGGATGAAAATGACAACAATGATGAGGCTGCCGATCAAAATCTGTTGCTTACCAGTGACGATGACGACGTGGATGACTTTGATGATGAGCAATCAAAGCATCTGCAGAAACCGTATTGCATCTATTGTAATAAAAAGTTCACCAGCCAATATAAGTTTGAGAATCACATGTTTGTACATCGCGGTTTGGCGCCGTATCGTTGTGAGCTGTGCACAAATCTATACAACATGAAACGTCTGCTCATTCGGCATTATAAGACGGTGCATAAACGCATGCCCACTAGGGACATGGTGCAAGCCAAGGGCGATAAGGTGTCTGTGGCCCGTACAACTATTGAAAAGATAAATGTTTATGTTGACAAAACTCCCACGCTAATGTGTGCAAAATGTCCATTTGAATGCGAGCTGGAGGGTGAAATGCGCAAGCATTTAAATGCACATCATGGCATCAACGATGGTGGCTCTACGCAGGCAAACGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCACGCTGTATTCGATCTTTTGCGGCTAAACGTACGCTTACAAGACATTTGCAACGTAGTCATTTAGTGGATACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCATCCACCACGACCACATCGACGGCTACAACCACATTGCCACTGAATGCCAGTGATagcaataaaacaacaacaacagcaatatccGGAGCAACAACTCAACTGGATGCGAACATATTGGCTCAGCATTTCGTTGACTCCGTCGATGGTGATGGCGGTGGTGaaggcgatggcgatggcaatGGAAAATGCGACAAGGACACAGGATGCACAACGGAAAATGTAAGCACAGATATCCACCCAGAAGCACAACACGAGACAACCGATTCAGCAACAACTGAAACTAcgaaagcaacagcaatatcAAACACGGAAGCCACAGAAGCAAAAACACCatcaataagaacaacaactgaagaaggaccgacaacgacaacaacaacaaccgtcGGCTCAACACTCTTTCCAACGCCCACGCCATTTGACTTTGATCTAGATTTTATGGGCAACGGTGAGCATGCCACGACCCTTAAGAACAACGATAGCTACAACATTGTACCGAATCCCAGTCATTTATTGAATGGAACCGATAAGCTATTGACTGACGCGTTGGAACCATCGCCAGTTAAAGATCTTCGCGCTCGTCTGCCCCGTACCCCCATATTTGTGTGCAAGCAATGCAATCAAACTTTCGATGAGCTCGGCAAGCTGGTGCAGCATGAATTGGAGCAACATTCCAGCGGCGTTGTATCACCGCGCATCAGCTACCAGCATCAATGCAAGATCTGTAATACAACATACCGTACCGTAACGCTACTTAACTATCATATGAAACGACATACGCCGGTAAATGTTGTGTGCAAGCAGTGTCCCAAAGAGTTTGCAAACATCTCTGATCTGGAACAGCATTTACTGTCAGAGCATAGCGCCGGTTCACAGGCTCCGCTGAAATGTGGCGTGGATGGTTGCACAAAGACATTTAACTACAAACATCATCTGAAACGGCATCAGACAGCTTCCCACACGCCCGTGCAGTATATCTGTCCAGAATGTGGATGCGATATGCTTACTAGTCTGCATCTCAGGAATCATATGTCCAGCCACAAGAGCACACACTCTTATAAGTGTCCTAAATGTGTGCGTACGTATATGAGACGCAATCCcTTTCGCAGACATGCGCTTCGGGAGCACAAGTGGGAGCTGACCGAGCAGGAGATagataaaatttattgctttaatGATATATCGTCATCAAGTAAATTGCGTGGACGTAGATCGTTGAAGGTTGATATCGAGCAATCTGACTAG
Protein Sequence: MAHKRVKTQDMAINYKFLCRCCLKSEAEFYKLDSLIECGGGESDASSTKIPLLRLLLFCMRIENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKNPTRFNGQQSAQWLELNESEDATQSRPWEQKSQKPVVRHECKVCGAIISNRMELKQHIRMHADQSSHQCKLCSFVTLKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQSAVNAIIAPKQIPIDTPAEDEQVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEQQLANSLPIIQSTNQTAEPTIGTANSANVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNANATSNVTLHNLFHDSKDDLTYNEMDIDLSHMVVDNVLPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSFYSLRSADLIQHYTTEHKSCVNESRSNHLDRSQLSFPADRSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQRNTDTMLSSGNASTQPDIPLGIKYPPITSTATTAATSSTTGLAQPPLATTTTTTVVTPMNDINVVVDTTSLFYAATAEQLPNNNATTATTTDSNTFSIFPEQSFANSLTTPTATPTTISVDTNGVVTTTSSTTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDEEDEEDAENEDENDNNDEAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTTIEKINVYVDKTPTLMCAKCPFECELEGEMRKHLNAHHGINDGGSTQANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSASTTTTSTATTTLPLNASDSNKTTTTAISGATTQLDANILAQHFVDSVDGDGGGEGDGDGNGKCDKDTGCTTENVSTDIHPEAQHETTDSATTETTKATAISNTEATEAKTPSIRTTTEEGPTTTTTTTVGSTLFPTPTPFDFDLDFMGNGEHATTLKNNDSYNIVPNPSHLLNGTDKLLTDALEPSPVKDLRARLPRTPIFVCKQCNQTFDELGKLVQHELEQHSSGVVSPRISYQHQCKICNTTYRTVTLLNYHMKRHTPVNVVCKQCPKEFANISDLEQHLLSEHSAGSQAPLKCGVDGCTKTFNYKHHLKRHQTASHTPVQYICPECGCDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTEQEIDKIYCFNDISSSSKLRGRRSLKVDIEQSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00502773;
80% Identity: -