Basic Information

Insect: Drosophila repleta
Gene Symbol: -
Assembly: GCA_018903745.1
Location: JAEIGN010000497.1:23269696-23274936[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0021 0.14 12.5 0.5 1 23 148 170 148 170 0.97

2 14 0.00013 0.008 16.4 1.3 1 23 395 417 395 417 0.98

3 14 1.5 95 3.5 0.8 1 23 423 446 423 446 0.94

4 14 3.1 2e+02 2.5 0.2 1 23 473 496 473 496 0.91

5 14 0.0011 0.071 13.4 1.9 3 23 769 789 768 789 0.92

6 14 0.044 2.8 8.4 1.4 1 23 795 818 795 818 0.98

7 14 2.4 1.6e+02 2.9 1.2 3 23 856 876 854 877 0.92

8 14 0.0077 0.49 10.7 0.8 1 23 898 921 898 921 0.97

9 14 0.013 0.86 10.0 0.3 1 23 1142 1165 1142 1165 0.91

10 14 0.0003 0.019 15.2 4.3 1 23 1178 1200 1178 1200 0.98

11 14 6.1e-05 0.0039 17.4 0.1 2 23 1206 1228 1205 1228 0.96

12 14 0.0011 0.071 13.4 4.1 2 23 1237 1261 1236 1261 0.90

13 14 0.042 2.7 8.4 0.6 1 23 1266 1288 1266 1288 0.97

14 14 0.0059 0.38 11.1 1.3 1 23 1294 1317 1294 1317 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0021	0.14	12.5	0.5	1	23	148	170	148	170	0.97
2	14	0.00013	0.008	16.4	1.3	1	23	395	417	395	417	0.98
3	14	1.5	95	3.5	0.8	1	23	423	446	423	446	0.94
4	14	3.1	2e+02	2.5	0.2	1	23	473	496	473	496	0.91
5	14	0.0011	0.071	13.4	1.9	3	23	769	789	768	789	0.92
6	14	0.044	2.8	8.4	1.4	1	23	795	818	795	818	0.98
7	14	2.4	1.6e+02	2.9	1.2	3	23	856	876	854	877	0.92
8	14	0.0077	0.49	10.7	0.8	1	23	898	921	898	921	0.97
9	14	0.013	0.86	10.0	0.3	1	23	1142	1165	1142	1165	0.91
10	14	0.0003	0.019	15.2	4.3	1	23	1178	1200	1178	1200	0.98
11	14	6.1e-05	0.0039	17.4	0.1	2	23	1206	1228	1205	1228	0.96
12	14	0.0011	0.071	13.4	4.1	2	23	1237	1261	1236	1261	0.90
13	14	0.042	2.7	8.4	0.6	1	23	1266	1288	1266	1288	0.97
14	14	0.0059	0.38	11.1	1.3	1	23	1294	1317	1294	1317	0.96

Sequence Information

Coding Sequence: ATGGCGCACAAGCGAATAAAAACAGAGGACATGGATCCGAATTACAAATTTTCGTGTCGCTGTTGCCTCAAATCCGAGGCGGAATTCTACAAACTGGACTCGCTAATTGAGTGCGGCAGTGGCGAAAGTGAAGCGTCCTCTACGAAAATGCCCCTTCTGCGTTTACTATTGTTCTGCATGCGCATCGAAAATCAGCCCGAGCTGCCGCAATACATATGCGTGGAGTGTACTAAAAGTTTGCAAATCGCGTACTATTTCATACAGAACGGTCTGCGAGCACACGAAATTCTGTGTCGGAAGCTGTGCCCTGGCAAGCTGAAGAGCTCGACGCGTGTTAATGGACAGCAGACAACGACAACGCAATGGGTCGAGTCGAAAGCGTGTGAGGATGCGACGCCGTCCAGGCTCTGGGAGCAAAAGCCACCGAAGCCCGCTGCGAGACACGAATGCAAAGTGTGCGGTGCCATTATATACAATCGCATGGAACTCAAGCAGCACATCAAAATGCACACAGATGCATCGAGTCATCAGTGCAAATTGTGCAGCTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAAGTACACGGACTGACGGCTGCCCAAATCGAGCATCAACTTAAGATCCGGAGATCCATGCAGGCAGCTGCAAACGCAATAACAGCACCGGCTAAAATAGCAATTGACACAGCAGCTGACGATAATCAAGTAAAGGTGTGCACCCTGGAGGATATGGAACTTCTGATACCCACTGTGCTGACTCCAGAAGATTTTTCGCATCCACAACTTGATGCGGATCAGCTGCGTGATATAGAGCAACAGTTGGCGAACTCGATGCCCATTACGCACTCCGCCAGCCAGCCAGCAGAGCCAACGATAGGAAGTGGAAATAGCGCCAACGTAAGCATAGGTGCCGAGTTTCTGGTCATGCCTGATGGCTCGTTGCAGCAAGTGAATGATGGAGGTGTGGTGTTCGAGTACATTGACGATAGCAAAAACAGCAATGCGACGAGTAATATGACATTGCAGAATCTATTGGATGACTCCAAGGTCGATTTAACATACAATGCAATGGATATCGATTTAACTCACATGGTTTTGGACAATGCATTGCCACAGATAACTGTCAAGCCAAAGCCGCGTCCAGCACCCGGGTCCACAGGCGCCCTCAAACATAAGTGCAAACTGTGTCCAAAAGCATTTCCCACGGTAGCACGTCTGAAATCTCATCAATTAACGCACAGTCATTTGCCTAAGTTCTATTGCGATCAGTGCTCTTATTATTCGCTACGCAGCGCCGATCTCATCCAGCACTATACGACGGAGCACAAGTCCTGCGTTAGCGAGAGTCGCTTGAATCATTTGGATAAGTCACAATTAATTTTGCCGGCGGATAGAAGTCGCATTTATTCCTGCGATTTGTGTTTGTTCGAAGCACCCACCAGTGGGAAATTGCGTGTACACTACAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAACTACGTCCCAGTTGGACTCATGAGCCGAAGCAAGGGAGCTCGTATACAATGGTAAATAATGGCACTGCTTCAAGTCAGCCCGATCTTCCACTTGGCATCAAATATCCCCCCATGACATCAACGGCAACCACGGTAGCAACTTCGTCAACGTCAACTGCATTGGCGCCACCAACTCTGGCATCAACAACAACAACCACAACGGTGGTACCACCTATGAATGACATTAATGTTGTGGTGGATACCACAGCATTGTTCTATGCAGCAGCTGCAGAGCAGTTACCGAATACTAATGCTGCAACATCAGAAACATCGGCAACAACAGAATCCAACACATTTTCAATGTTTCCTGAGCAATCTTTTGTTAACAGTCTAACAACACCAGTAACAACGCCGACAACAGTTTCAGTAGATACAAACGGTGTGACAACTACCGCTTCGGCGACAACAAACCCAAACACAAGCATATTTGGTGATATGCAGGATTTTATAGACAATACCGATGTGGCGGCTATTTGTACCATACCCGCCGATGATATGCCTGTCGTTGATGGAGACGATATTGTTATTGATAACAATAATATCAGCTTAGATTTTGATGCGGAAAATCTTTTTGAGGATTTTGAAGATGTCGAGGTTGGCGAAGAGGATGAAGAAGACGAGGAGGACGCTGAAAATGAGGATGAAAATGAAAATAACGATGCGGCTGCCGATCAAAATCTGTTGCTTACCAGTGATGACGACGACGTGGATGACTTTGATGACGAACAGTCAAAGCATCTGCAGAAGCCGTATTGCATCTATTGTAATAAAAAATTCACCAGCCAATATAAGTTTGAAAATCACATGTTTGTGCATCGCGGATTGGCGCCATATCGCTGTGAGCTCTGCACAAATCTGTATAATATGAAACGTCTTCTCATTCGGCATTATAAGACGGTTCATAAACGCATGCCCACACGGGACATGGTGCAGGCCAAGGGCGACAAGGTGTCTGTAGCCCGCTCAGCCGTTGAAAAGATAAATGTTCAAGTTGACAAAAATCCCATGGTAATGTGCGCGAAGTGTCCATTTGAATGCGAACTGGAGGAAGAAATGCGCAGACATTTAAATGCACATCATGGTATTAACGATGGTGGCTCAACGCATGCTAATGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCACGCTGTATTCGGTCCTTTGCGGCTAAACGCACACTCACACGACATTTGCAACGTAGTCATTTAGTGGATACTATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCTGCGGCCACCACGACGACATCAACGGCAACAACTACATTGCCGCAGAATGCTAGTGATGGGAATAAAATAACCACAACATCCGGAGCAACAAGTGAACTGGATTCGAATATATTGGGCCAGCATTTCGCTGACTCTGTGGATGGTGCTGGCAATGGTGAAGGCGATGGCGATGGCAGTGGAAAATGCGACAAGGACGCAGCATGTACAATGGAAGATGTAAGCACAGATATACAAACCGAAGCACCACAAGAGACAGTCGATGCAGCAACAATTGAAACTACAAAATCTGCAACAATACCAAATACCGAAGCTACAAAAGCTGAAATATCATCAATAACAACAACAACAGTAACAACAGCAACAGAAGAAGGAGGACCAGCAACAACAAAAGCCGCTGGTTCAACATTATTTCCAACGCCTACGCCCTTTGACTTTGATCTTGATTTTATGGGCGATGGTGAGCATGTCACCACTATTAAGAACAACGACAACTTCAACATTGCGCCGAACCCCAGTCATCTGCTGAATGGAACCGATAAGTTACTGACTGCTGCGTTAGAGCCATCGCCAGTTAAAGATCTTCGATCGCGCCTGCCCCGTACACCGATATTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTTGGCAAGCTGGTGCAGCACGAAATGGATCAACATTCCAGCGGCATTGTATCGCCGCGCATCGGCTACCAGCATCAGTGCAAGATCTGCAATACCACATATCGCACCATAACGCTTCTTAACTATCATATGAAGCGACATACGCCAGTAAAAGTTTCGTGCAAACAGTGCCCCAAAGAGTTTGCAAACATTTCCGATTTGGAGCAACATTTACTGACGGAGCATAGTGTCGCAGCACAGGCGCCTCTCAAGTGTGGCTTAGATGGCTGCACAAAGACATTTAACTACAAACATCATTTGAAACGGCATCAGACGGCCTCTCACACGCACGTACAGTATATCTGTCCAGAATGCGGACGCGATATGCTTACTAGTCTGCATCTCAGGAATCACATGTCCAGCCACAGGAGCAAACACTCTTACAAGTGTCCCAAATGTGTTCGAACCTATATGAGGCGCAATCCCTTTCGCAGACATGCTCTACGTGAGCACAAGTGGGAGCCAACCGAGGAAGAGATTGATCAAATTTATGGCGTTAATGATATACAGACTTTCAGTAAAGCTCGCGGACGTAAATCGTTGAAGGTTGACATCGAGAATTCTGATTAG
Protein Sequence: MAHKRIKTEDMDPNYKFSCRCCLKSEAEFYKLDSLIECGSGESEASSTKMPLLRLLLFCMRIENQPELPQYICVECTKSLQIAYYFIQNGLRAHEILCRKLCPGKLKSSTRVNGQQTTTTQWVESKACEDATPSRLWEQKPPKPAARHECKVCGAIIYNRMELKQHIKMHTDASSHQCKLCSFVTLKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQAAANAITAPAKIAIDTAADDNQVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEQQLANSMPITHSASQPAEPTIGSGNSANVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNSNATSNMTLQNLLDDSKVDLTYNAMDIDLTHMVLDNALPQITVKPKPRPAPGSTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCVSESRLNHLDKSQLILPADRSRIYSCDLCLFEAPTSGKLRVHYSDKHLIVPSEVQLRPSWTHEPKQGSSYTMVNNGTASSQPDLPLGIKYPPMTSTATTVATSSTSTALAPPTLASTTTTTTVVPPMNDINVVVDTTALFYAAAAEQLPNTNAATSETSATTESNTFSMFPEQSFVNSLTTPVTTPTTVSVDTNGVTTTASATTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDEEDEEDAENEDENENNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARSAVEKINVQVDKNPMVMCAKCPFECELEEEMRRHLNAHHGINDGGSTHANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPQNASDGNKITTTSGATSELDSNILGQHFADSVDGAGNGEGDGDGSGKCDKDAACTMEDVSTDIQTEAPQETVDAATIETTKSATIPNTEATKAEISSITTTTVTTATEEGGPATTKAAGSTLFPTPTPFDFDLDFMGDGEHVTTIKNNDNFNIAPNPSHLLNGTDKLLTAALEPSPVKDLRSRLPRTPIFVCKQCNQTFDELGKLVQHEMDQHSSGIVSPRIGYQHQCKICNTTYRTITLLNYHMKRHTPVKVSCKQCPKEFANISDLEQHLLTEHSVAAQAPLKCGLDGCTKTFNYKHHLKRHQTASHTHVQYICPECGRDMLTSLHLRNHMSSHRSKHSYKCPKCVRTYMRRNPFRRHALREHKWEPTEEEIDQIYGVNDIQTFSKARGRKSLKVDIENSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00568517;
80% Identity: -