Basic Information

Insect: Drosophila eohydei
Gene Symbol: -
Assembly: GCA_035045825.1
Location: JAWNOT010000072.1:22926480-22931987[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00025 0.017 15.5 0.4 1 23 146 168 146 168 0.98

2 14 0.00014 0.0093 16.4 1.3 1 23 392 414 392 414 0.98

3 14 1.6 1.1e+02 3.6 0.8 1 23 420 443 420 443 0.94

4 14 0.84 57 4.4 0.2 1 23 470 493 470 493 0.92

5 14 0.0012 0.082 13.4 1.9 3 23 761 781 760 781 0.92

6 14 0.048 3.3 8.4 1.4 1 23 787 810 787 810 0.98

7 14 3.3 2.3e+02 2.6 1.3 2 23 847 868 846 869 0.85

8 14 0.0083 0.57 10.8 0.8 1 23 890 913 890 913 0.97

9 14 0.016 1.1 9.8 0.3 1 23 1132 1155 1132 1155 0.91

10 14 0.0003 0.02 15.3 4.2 1 23 1168 1190 1168 1190 0.98

11 14 0.00012 0.0085 16.5 0.1 2 23 1196 1218 1195 1218 0.96

12 14 0.00095 0.065 13.7 3.8 2 23 1227 1251 1226 1251 0.90

13 14 0.51 35 5.1 1.9 1 23 1256 1278 1256 1278 0.95

14 14 0.0064 0.43 11.1 1.3 1 23 1284 1307 1284 1307 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00025	0.017	15.5	0.4	1	23	146	168	146	168	0.98
2	14	0.00014	0.0093	16.4	1.3	1	23	392	414	392	414	0.98
3	14	1.6	1.1e+02	3.6	0.8	1	23	420	443	420	443	0.94
4	14	0.84	57	4.4	0.2	1	23	470	493	470	493	0.92
5	14	0.0012	0.082	13.4	1.9	3	23	761	781	760	781	0.92
6	14	0.048	3.3	8.4	1.4	1	23	787	810	787	810	0.98
7	14	3.3	2.3e+02	2.6	1.3	2	23	847	868	846	869	0.85
8	14	0.0083	0.57	10.8	0.8	1	23	890	913	890	913	0.97
9	14	0.016	1.1	9.8	0.3	1	23	1132	1155	1132	1155	0.91
10	14	0.0003	0.02	15.3	4.2	1	23	1168	1190	1168	1190	0.98
11	14	0.00012	0.0085	16.5	0.1	2	23	1196	1218	1195	1218	0.96
12	14	0.00095	0.065	13.7	3.8	2	23	1227	1251	1226	1251	0.90
13	14	0.51	35	5.1	1.9	1	23	1256	1278	1256	1278	0.95
14	14	0.0064	0.43	11.1	1.3	1	23	1284	1307	1284	1307	0.96

Sequence Information

Coding Sequence: ATGGCCCACAAACGAGTAAAAACACAGGACATGgcaataaattacaaatttttgtgTCGCTGTTGTCTCAAATCTGAGGCGGAATTCTATAAACTAGACTCACTCATCGAGTGCGGCGGTGGCGAAAGTGACGCGTCTTCTACAAAAATACCCCTTCTACGTTTACTATTATTCTGCATGCGTATCGAAAATCAGCCCGAGTTGCCGCAATATATATGCGTGGAGTGCAGTAAAAGTTTGCAAATTGCCTACTATTTCATTCAAAACGGCCTGCGAGCACATGAAATACTCTGTCGTAAATTGTGTCCCGGGAAGCTGAAGAATCCAACGCGTTTTAATGGCCAACAGTCAACGCAATGGCTCGAGTCGAACGAGAGTGAGGATGCGACGCAGTCCAGGCCCTGGGAGCAAAAGTCACAAAAGCCTGTTGTGCGACATGAATGTAAAGTATGCGGTGCCATTATATCCAATCGTATGGAGCTCAAGCAGCACATACGTATGCACGCAGATCAATCGATCCATCAGTGCAAATTGTGCAGTTTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTACCGCAAAGTACACGGCTTGACGGCTGCCCAAATCGAGCATCAACTTAAGATCCGAAGATCCATGCAGTCAGCTGCAAACGCAATAATAGCGCCGAAACAAATACCAATAGATACACCTGAGGATGAGCAAGTGAAGGTTTGCACTCTGGAGGATATGGAACTGCTGATACCCACTGTTTTGACACCAGAAGACTTTTCGCATCCTCAACTTGATGCGGATCAGCTACGTGATATAGAGGAACAATTGGCAAACTCGTTGCCAATTATACAGTCCACCAATCAGCCGGCCGAACCAACGATAGGGACTGCCAATAGCGCCAATGTCAGCATCGGTGCCGAATTTTTGGTCATGCCCGATGGCTCCCTACAGCAAGTGAATGATGGCGGTGTGGTATTCGAATACATTGACGATAGTAAAAACGCCAATCCAACAAGTAATGTAACATTGCACAATCTATTTCATGATTCCAAGGACGATTTAACATATAATGAAATGGATATCGATTTAAGCCATATGGTTGTGGATAATGTGTTGCCACAGATAACAGTCAAGCCAAAGCCGCGCCCAGCACCCGCATCCACTGGTGCCTTGAAACATAAATGCAAACTGTGTCCCAAAGCATTTCCCACGGTGGCACGTCTGAAATCTCATCAATTAACGCATAGTCATTTACCTAAATTCTATTGCGATCAGTGCTCTTATTATTCGCTACGCAGTGCAGATCTCATTCAGCATTATACGACGGAGCACAAGTCCTGTGTTAACGAGAGTCGTTCGAATCATTTGGATAGATCACAATTGAGTTTTCCGGCGGATAGAAGTCGCATTTATTCCTGCGATATGTGTTTGTTCGAAGCACCCACCAGTGGACAATTGCGTGTACACTATAGCGATAAGCATCTGATAGTGCCCAGTGAGGTGCAACTGCGGCCCAGTTGGACGCATGAGCCAAAGCAGAGGAATACTGATACAATGCTAAGCAGTGGAAATGCATCCACTCAGCCCGATATTCCATTGGGTATCAAATatCCTCCCATAACGTCAAcggcaacaactgcagcaacttcATCAACAACTGGGTTGGCGCAGTCAccgctggcaacaacaacaacaaccacggTGGTAACGCCTATGAATGACATTAATGTGGTGGTGGATACCACATCATTGTTCTATGCAGCGACTGCAGAGCAGTTACCAAATAATAATGCTACAACAGCGACAACTACAGATTCaaacacattttcaatatttcccGAGCAATCTTTTGCCAACAGTttaacaacaccaacagcaacccCGACCACAATTTCAGTGGACACAAACGGTGTGGTAACAACCACATCATCGACAACAAATCCAAACACAAGCATCTTTGGGGACATGCAGGATTTTATAGATAATACCGATGTCGCTGCTATTTGTACCATACCCGCCGATGATATGCCTGTCGTGGATGGAGATGATATTgttattgataataataatatcagtTTAGATTTTGACGCGGAAAATCTATTTGAGGACTTTGAAGATGTCGAGGTTGGCGAAGAGgatgaagaagatgaagaagatgcTGAAAACGAGGATGAAAATGACAACAATGATGAGGCTGCCGACCAAAATCTGTTGCTCACCAGTGACGATGACGACGTGGATGACTTTGATGATGAGCAATCAAAGCATTTGCAGAAACCGTATTGCATCTATTGTAATAAAAAGTTCACGAGCCAATATAAGTTTGAGAATCACATGTTTGTACATCGCGGTTTGGCGCCGTATCGTTGTGAGCTGTGCACAAATCTATACAATATGAAACGGCTGCTTATTCGGCATTATAAGACGGTGCATAAACGCATGCCCACTAGGGACATGGTGCAAGCCAAGGGCGATAAGGTGTCTGTGGCCCGTACAACTATTGAAAAGATAAATGTTTATGTTGACAAAACTCCCACGCTAATGTGTGCAAAATGTCCATTTGAATGCGAGCTGGAGGGTGAAATGCGCAAGCATTTAAATGCACATCATGGCATTAACGACGGtgGCTCTACGCAGGCAAACGAGGTGTTTATCATACGCAAACTGCCCTATGACTGTCCACGCTGTATTCGATCTTTTGCGGCTAAACGTACGCTTACAAGACATTTGCAACGTAGCCATTTAGTGGATACAATTATTGAGATGCAGGCGCCTCAATTGACAACTAGTTCAGCATCCACCACGACCACATCGACGGCTACAACCACGTTGCCGCTGAATGCCAGTGATagcaataaaacaacaacaacggcaataTCTGGAGCAACAACTCAACTGGATGCGAACATATTGGCTCAGCATTTCGTTGACTCTGTCGATGGTGATGGCGGTGGTGaaggcgatggcgatggcaatGGAAAATGCGACAAGGACACAGGATGCACAACGGAAAATGTAAGCACAGATATACACCCAGAAGCACAACAAGAGACAACCGATTCAGCAACAACTGAAACTACAAAAGCAACGGCAATATCAAACACTGAAGTCACAGAAGCAAAAACACCAccaataagaacaacaactgaagAAGGACCcacaacgataacaacaacaaccgccgGCTCAACACTCTTTCCAACGCCCACGCCATTTGACTTTGATCTAGATTTTATGGGGAACGGTGAGCATGCCACGACCCTTAAGAACAACGATAGCTACAACATTGTACCGAATCCCAGTCATTTATTGAATGGAACCGATAAGCTATTGACTGACGCGTTGGAACCATCGCCAGTTAAAGATCTTCGCGCTCGTCTGCCCCGTACCCCCATATTTGTGTGCAAGCAATGCAATCAAACTTTCGATGAGCTCGGCAAGCTGGTGCAGCATGAATTGGAGCAACATTCCAGCGGCATTGTATCACCGCGCGTCAGCTACCAGCATCAATGCAAGATCTGTAATACAACATACCGTACCGTAACGCTACTTAACTATCATATGAAACGACATACGCCGGTAAATGTTGTGTGCAAGCAGTGCTCCAAAGAGTTTGCAAACATCTCCGATCTGGAACAGCATTTACTGACAGACCATAGCGCCGGTTCACAGGCTCCGCTGAAATGTGGCGTGGATGGTTGCACAAAGACATTTAACTACAAACATCATCTGAAACGGCATCAGACAGCCTCCCACACGCCCGTGCAGTATATCTGTCCAGAATGTGGATGCGATATGCTTACAAGTCTGCATCTCAGGAATCATATGTCCAGCCACAAAAGCACACACTCTTATAAGTGTCCTAAATGTGTGCGTACGTATATGAGACGCAATCCcTTTCGCAGACATGCGCTTCGGGAGCACAAGTGGGAGCTGACCGAGCAGGAGATagataaaatttattgctttaatGATATATCGTCATCAAGTAAATTGCGTGGACGTAGATCATTGAAGGTTGATATCGAGCAATCTGACTAG
Protein Sequence: MAHKRVKTQDMAINYKFLCRCCLKSEAEFYKLDSLIECGGGESDASSTKIPLLRLLLFCMRIENQPELPQYICVECSKSLQIAYYFIQNGLRAHEILCRKLCPGKLKNPTRFNGQQSTQWLESNESEDATQSRPWEQKSQKPVVRHECKVCGAIISNRMELKQHIRMHADQSIHQCKLCSFVTLKHRQLPEHYRKVHGLTAAQIEHQLKIRRSMQSAANAIIAPKQIPIDTPEDEQVKVCTLEDMELLIPTVLTPEDFSHPQLDADQLRDIEEQLANSLPIIQSTNQPAEPTIGTANSANVSIGAEFLVMPDGSLQQVNDGGVVFEYIDDSKNANPTSNVTLHNLFHDSKDDLTYNEMDIDLSHMVVDNVLPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCSYYSLRSADLIQHYTTEHKSCVNESRSNHLDRSQLSFPADRSRIYSCDMCLFEAPTSGQLRVHYSDKHLIVPSEVQLRPSWTHEPKQRNTDTMLSSGNASTQPDIPLGIKYPPITSTATTAATSSTTGLAQSPLATTTTTTVVTPMNDINVVVDTTSLFYAATAEQLPNNNATTATTTDSNTFSIFPEQSFANSLTTPTATPTTISVDTNGVVTTTSSTTNPNTSIFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDEEDEEDAENEDENDNNDEAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVARTTIEKINVYVDKTPTLMCAKCPFECELEGEMRKHLNAHHGINDGGSTQANEVFIIRKLPYDCPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSASTTTTSTATTTLPLNASDSNKTTTTAISGATTQLDANILAQHFVDSVDGDGGGEGDGDGNGKCDKDTGCTTENVSTDIHPEAQQETTDSATTETTKATAISNTEVTEAKTPPIRTTTEEGPTTITTTTAGSTLFPTPTPFDFDLDFMGNGEHATTLKNNDSYNIVPNPSHLLNGTDKLLTDALEPSPVKDLRARLPRTPIFVCKQCNQTFDELGKLVQHELEQHSSGIVSPRVSYQHQCKICNTTYRTVTLLNYHMKRHTPVNVVCKQCSKEFANISDLEQHLLTDHSAGSQAPLKCGVDGCTKTFNYKHHLKRHQTASHTPVQYICPECGCDMLTSLHLRNHMSSHKSTHSYKCPKCVRTYMRRNPFRRHALREHKWELTEQEIDKIYCFNDISSSSKLRGRRSLKVDIEQSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512961;
90% Identity: iTF_00520160;
80% Identity: -