Nmel003062.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Nomia melanderi
Gene Symbol
bab1
Assembly
GCA_003710045.1
Location
NW:3857213-3863713[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 2.2e-28 3.9e-26 90.4 0.0 1 101 23 120 23 125 0.95

Sequence Information

Coding Sequence
ATGGCGAGCACGTCGCAGCAGTACTGCCTACGCTGGAACAACCACCGTTCGAACCTGCTGACAGTGTTCGACGAGCTGCTGCAGAACGAGGCGTTCACCGACGTGACGCTCGCGGTGGACGGCGGTGCCTCGGTAAAATGTCACAAAATGGTACTAGCCGCCTGCTCCTCTTACTTTCAAACGTTGTTCATCGATTTGCCGTGTAAACACCCGATCGTCGTCCTCAAAGACGTCAAGTACTCCGAGATCAAGGCCATTCTCGAGTACATGTACCGGGGTGAGGTGAACGTGGCACAGGAGCAATTGGCTGGCCTGCTGAAGGTCGCTGAGGTGTTGAAGGTGAAGGGCCTGGTGGAGGAGAACGGTTCCCAAGGCCGACGTGAGGAAGTCGAAACCTCGATGTCTCCTCCGCCAGCGATCAGCACGAGCACCAGCAGCGCGGCTCACAGCAGCGGTCACGCGTCACCGCCACACTCCACTGGAACTTCCTACAACGTGTACGGCAAGTCGTCGGTGGAGAGGAGCGCCAGCCGCCTGCCGTTGCACATGTGGCCTCTATCGGGGATTCCCATCTCCTCGCACTCCAGTAATCACCAAGTAGCGACTCATCCGCAACATTCCATTCTCACCGGTTCCTACGACAACGGCTTCGAGACCTCGCCGCTGAAACGGAAGAAGCTCTCCAACATGATGATAAACAGAGACACGCCGATACTCAGGACAGTGCTGGGCCAGGGACACGCGGACAGCTCGCAGGGCATCCCTCTGTTGCACCCGGACAGCCACGAGAATCACTTCAGGAACAACAGCAATGGCTCCTCGCACGAGGGCGACCGGCGCAGCAGCACTGACATCGCTCACGGGGAACCTGCACACAGCCCTTACACGGACGTATCTATGATGGACGAGGATGACAAGCAACCCTCGCCGCAGTCGTATCCTGGAGAGGTTAAGTCAGGGATCGTCAATTATGTTCCAACGCAGAAGCCTGAATGGAAACGATACAAGCAATACACACGAAACGACATCATGTCCGCTATCGAGGCTGTACGTTCAGGAATGAGTGCCCTGCAGGCGGCGCGTAAGTATGGCGTACCATCTCGAACCCTTTACGATAAGGTGAAGAAGCTGGGCATTACAACATCACGGCCGTTTAAACGCGGCTCGAACGGCAGCGGCGCATGTTTCCCTTACGGAATCGGCGGCAACGTGAATGGAAGTATATACGGTGGCGCATTGTCCGAGAACGAAAACGACAACAGCAACGCAGTAATTGAAAATCCTGGGTCGATGCTAGACACGTACAAAGCCAGAGACGGCCCCATTGATCGGGAAATGTTAGACATCACTCGGTGCAGTCCTAGCCCCGTTATACATTCTGTGAAACAGCAGAGTAACGAGGATCAGGTGGAGGACCTCTCCGTGAGTCGTAAGTCGGATGTCCGTGTGATAGTCCCGCCTACGTCGGCTATCAAAGAGGAGGAAGACATTGGTTCTGATTCGTGTAACCATAACTAA
Protein Sequence
MASTSQQYCLRWNNHRSNLLTVFDELLQNEAFTDVTLAVDGGASVKCHKMVLAACSSYFQTLFIDLPCKHPIVVLKDVKYSEIKAILEYMYRGEVNVAQEQLAGLLKVAEVLKVKGLVEENGSQGRREEVETSMSPPPAISTSTSSAAHSSGHASPPHSTGTSYNVYGKSSVERSASRLPLHMWPLSGIPISSHSSNHQVATHPQHSILTGSYDNGFETSPLKRKKLSNMMINRDTPILRTVLGQGHADSSQGIPLLHPDSHENHFRNNSNGSSHEGDRRSSTDIAHGEPAHSPYTDVSMMDEDDKQPSPQSYPGEVKSGIVNYVPTQKPEWKRYKQYTRNDIMSAIEAVRSGMSALQAARKYGVPSRTLYDKVKKLGITTSRPFKRGSNGSGACFPYGIGGNVNGSIYGGALSENENDNSNAVIENPGSMLDTYKARDGPIDREMLDITRCSPSPVIHSVKQQSNEDQVEDLSVSRKSDVRVIVPPTSAIKEEEDIGSDSCNHN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01070954; iTF_00216993; iTF_00218337; iTF_00219201; iTF_00216482; iTF_00223106; iTF_00982210; iTF_00230115; iTF_00233315; iTF_00221348; iTF_00982372; iTF_00215109; iTF_00217157; iTF_00219717; iTF_00225157; iTF_00231237; iTF_00217670; iTF_00228583; iTF_00217832; iTF_00982888; iTF_00983048; iTF_00225833; iTF_00219882; iTF_00222442; iTF_00227882; iTF_00231402; iTF_00225324; iTF_00215629; iTF_00230766; iTF_00215792; iTF_00218512; iTF_00223280; iTF_00223793; iTF_00226002; iTF_00222611; iTF_00226515; iTF_00216308; iTF_00220501; iTF_00873877; iTF_00228055; iTF_00228759; iTF_00219032; iTF_00873720; iTF_00224474; iTF_00226682; iTF_00229274; iTF_00230618; iTF_00220667; iTF_00223964; iTF_00227196; iTF_00229436; iTF_00224637; iTF_00229949; iTF_00233149; iTF_00221183; iTF_00227359; iTF_00214944; iTF_00963778; iTF_00962596; iTF_00963109; iTF_00964389; iTF_00963280; iTF_00961745; iTF_00964563; iTF_00963927; iTF_00961914; iTF_00962426; iTF_01419560; iTF_01419720; iTF_01421011; iTF_01420855; iTF_01418430; iTF_01418272; iTF_00684238; iTF_00684720; iTF_00684089; iTF_00684859; iTF_01122355; iTF_01122535; iTF_01417785; iTF_01417624; iTF_00983677; iTF_00983537; iTF_01424287; iTF_01424463; iTF_00088132; iTF_00086407; iTF_00084653; iTF_00086093; iTF_00087853; iTF_00087023; iTF_00087287; iTF_00088700; iTF_00088925; iTF_00084448; iTF_00862482; iTF_00862665; iTF_00085503; iTF_00085204; iTF_00360134; iTF_00360300; iTF_00360830; iTF_00360990; iTF_00142535; iTF_00141161; iTF_00141295; iTF_00141908; iTF_00141752; iTF_00140506; iTF_00140670; iTF_00142399; iTF_00183207; iTF_00183366; iTF_00762472; iTF_00762641; iTF_00763155; iTF_00763317; iTF_01418921; iTF_01419078; iTF_00676110; iTF_00675942; iTF_01539694; iTF_01539523; iTF_00633551; iTF_00391214; iTF_00391423; iTF_00633728; iTF_00625585; iTF_00625418; iTF_00184024; iTF_00183864; iTF_00864729; iTF_00864559; iTF_00306172; iTF_00306370; iTF_00863357; iTF_00863193; iTF_00860487; iTF_00865418; iTF_00861260; iTF_00860303; iTF_00865237; iTF_00861052; iTF_01498301; iTF_01498116; iTF_00861982; iTF_00861797; iTF_00024703; iTF_00024542; iTF_00761056; iTF_00760910; iTF_00863872; iTF_00864063; iTF_00866627; iTF_00866788; iTF_00865926; iTF_00866102; iTF_01169088; iTF_01169260;
90% Identity
iTF_01070954;
80% Identity
iTF_01070954;