Dbun010721.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila bunnanda
Gene Symbol
RREB1
Assembly
GCA_008042815.1
Location
VNKE01003966.1:21012-26947[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.032 2.3 8.8 0.8 1 21 257 277 257 279 0.93
2 12 0.0003 0.021 15.1 0.2 1 23 289 311 289 311 0.98
3 12 7.2e-05 0.0051 17.1 7.3 1 23 317 339 317 339 0.98
4 12 1.9 1.3e+02 3.2 3.7 2 19 557 574 557 576 0.97
5 12 0.0075 0.53 10.7 0.1 1 23 724 746 724 746 0.97
6 12 1.1e-05 0.00078 19.7 0.7 1 23 756 778 756 778 0.99
7 12 0.00074 0.052 13.9 2.0 1 23 784 807 784 807 0.97
8 12 0.0026 0.19 12.2 2.0 1 23 1076 1099 1076 1099 0.95
9 12 7.7e-05 0.0055 17.0 0.3 2 23 1486 1507 1485 1507 0.97
10 12 0.13 9.2 6.9 6.3 1 23 1513 1536 1513 1536 0.97
11 12 0.0075 0.53 10.7 0.5 3 23 1745 1765 1743 1765 0.96
12 12 0.0012 0.088 13.2 4.8 1 23 1771 1793 1771 1793 0.99

Sequence Information

Coding Sequence
ATGCTCGCgacacagcaacaacaacaagcacagcccggcagcagcaacaacaataacgtAGCCGCCTCCGCTCACACAAAGatgaacagcaacaacacagaCATTGCAGCAGAGATGGAGCGGAAGCGAAGAGAGTCCACAACGTCAGAATCCTCTCTCGAGCATCTCGACCTCGGTCGTACGCCAAAGAAGCTCAGCGGCAGCGCCGGCGCCGCTCAGTCGACATCAACGCCGCACGAGGTGGCAGTGACATCCCGTAAGCGCAAGTTGCGCcagttgcagcaacagcaccaccagcatcaCCAGCAAAGTCGGTCGGATCTTCTCAcggatgaggacgaggacgaggacgaggcgcGTCCCCTCAATCGGCACAAGCAGCGACGCGGTGCCGCCGCTCAGGGatcctcctccaccgccgccattGTTGTTGACTACTCTGCCGGCGACGCCAGCTCGCTGCGCAAAAAGTTCCGCCTCAATCGCTCGGCGGCAAGTCTCTCGGAATCGGGATTCGTGGATGCCAGCAGCACGGCCCACAGTGGCTATCTGGGGAACAatagcagcagcgccagcacaAGCCTGGCAGTGCCTTCTGTCCCCACATCCGCAGCCGGCGGAGCAGCCGCCTCCGCctcgaacagcagcagcaccagcacgagcagcaacagcagcagcattggcGGCGGTTCTGGTGGCTCCTCGCCGCAGGGCCTGTGCCTCTCCAGCGGCGAGTCGGGCATCGGTGCCGGCGACGAGCACATGAAATACCTGTGCCCCATCTGCGAGGTGGTCTCTGCCACGCCGCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAATGGGGACACGGAGAATTTCACCTGCCGCATCTGCTCCAAGGTGCTATCTTCAGCCTCATCCCTGGACAGGCACGTGCTGGTGCATACGGGCGAGCGGCCGTTCAACTGTCGCTACTGCCACCTGACCTTCACCACCAACGGCAATATGCACCGTCACATGCGCACCCACAAGCAGCACCAGACGGCGCAGTCCCAGTCACAGTCCCAGAGTCAGGCCCAGTTGCAGCgccgtcagcagcagcagcagcagcaacagcagccgacTCAtcccgcccagcagcagcagcagcagccacagcagcagacGCTGGCCAGCTCCCTGCCCGTGCGGGCGGAGAGCTATGAAAGCGATGCCAGTTGTTCCACTGATGTCTCCAGCGGTAAtagtcgcagtcgcagcagcagctccctccacaacaacaacaacaactcccACAAGgctaccaacaacaacaggagcagcaagCATGAGCTTGAGGAGTtggaggagcaggacctggaggataacaagcagcagctgcagcgtcGCCTGAAAACAACCATCAACAACAATGTCATCGATGCCGAGAATCCTGTGGAGGAGGATCTGCatggcgaggaggaggacgcaGACGATGTGGCCATGCTCACGAGCACACCCGATGTGGCCACCCTGCTGGCAGGTGCCAGTGCCTCCGGTGCTGCCTCCCGTtcgccctcgccctcgccACCCGGCTCGCCTGGCCTGCTCCTGAGTTGCCCCGCCTGCGGAGCCTCCGACTTCGAGACCCTGCCTGCCCTGTGCGCCCATCTGGATGCCCGGCATTCGGATATACCGGCCAAGTGCCGGGACTGTGAGGTGATCTTTGCCAGCCATCGCCAGCTGCAGGCGCACTGCTGCCGGGGATCTTCATTGGGAGTGGGACTGCCGCCTATGCTGGGTGCCAGCAGCTCGCCGCTCCACGCCGACGAGGATGCCGAagacgaggaggaggcggatcACGAAGATGATGAGGAAATGGAGCAGAAGCGCGATGACTTCTTCCACAAGCTGTACCTCAAGGGATCATCTGGTGCAGCGGGTGGCAACGGTGTTGGCGGCATTATCTCGCACCCGCCGTCGCCCATTAAGCACGAGCCGGCGGATAGCAAGGATCTGGCCGATATACAGAGCATCCTGAACAtgaccagctccagctgcaccAGCAGCTTCCTGCGCAACTTTGAGCAGTCGGTCAATACGCCCAGCTCCAGCCAATACAGCCTGGATGGGCGCgatcaggaggaggaggcccaGGATGCCTTCACCTCGGAATTCCGCCGGATGAAGCTACGCGGGGAGTTCCCCTGCAAGCTCTGCACCGCCGTATTTCCCAATCTACGCGCTCTCAAGGGTCACAACCGGGTGCACCTCGGTTCGGTTGGACCCGCAGGACCCTTCCGTTGCAACATGTGCCCCTACGCTGTCTGCGACAAGGCGGCTCTGGTGCGGCACATGCGCACCCACAATGGCGACCGTCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGTGAGCGTCACTTGAGGAATCGCCACGGCAAGACCAGCCGCGAGGAGGTGAAGCGTGCCATCGTCTACCATCCCGCCGAGGACGCCGGCTGTGAGGACAGCAAGTCGCGGCTGGGCGAGGATCTGGCCGATATGAGCTTCCGCTCAATAAGTCCAAccccgccgccaccgccgccgccggttgGTGAGAGCAGCAGCTCCCAGCTGAAGCACATGCTCTTGggcgagcagcagcatcataaTCATCACCATACGGTGGCGCCAGCCCAGCCGCCATTGAAGATTCAAGTGAAGAGCCTGGACCAGCTGGTGGACAAGAAACCAGCGCCAGTTCAACAGCCGGAGAAGAGCTCCTCCGCCTTGGACTTCAGCATGGATGTGTTGGATCTCAGCAAGAAGCCAACGGGTGCAGCCACGACGCCCACACCGACACCCACGCCCTCACTTACGCCAGCACCCCTCGGTGCGTCTGCAGTGGTGGCACCGGCTGCAGATCTGGCCGCCGCATTGGAGCAACAACAGTTGCTCCTGGCACAGCAGCAACTCTTTGGCGGTGCCGGTGACGCTGCCTCTCAGTACATGCAGCAGCTGTTCCGCAGCCTGGTGTTCCAGTCCCAGACGCCGGGCTTCTCCTTCTTCCCATTCATGGCCCCACCGCCGCCGGAGGTGAACCCAGAGAAGCCGCCACTGGTGAGTCCTCCATCCCGGATGAACCCACTGCCCGTGGGCGTTGGTGTGCCAGTGCCGCCCGGCGGACCCGTCAAGATGGTCATCAAGAACGGAGTGTTGATGCCTAAGCAGAAGCAGCGTCGCTACCGCACCGAACGTCCCTTTGCCTGCGAGCACTGCTCCGCCCGGTTCACGCTGCGCTCCAACATGGAGCGCCATgtgaagcagcagcatccgcagTTCTATGCCCAGCGACAGCGCAGCGGTCACCATGTGATGAGGGGCAGGGGCGCCTCGaatgccgccgctgctgctgctgccgctgccgctgcagcggtTGCCATGGGTCCAGCAGGAGGATCATCCCATCATCATGGTCACGCCCACAGTCACGGCCACAATCACAGCCACAACCATGGCCATGGACATGGGCATGCTCCCATCTCCGAGCAGGTGAAGTACGCCATTTTGGCGCAGCAGCTGAAGGCGCACAAGAACACCGATCTCCTGCAGCAGGCCCTGGCCCATGGCTCTAGCAGTGTGGCAGGCAATCCCCTGCTGCACTTCGGCTATCCACTGGGGCCCGCTCCTGGAGCTCCGCATGTGAGCAGTCAGGGAAACGGCCAGACGCCGCTGACCATGGACGATGACGAGCCCAAGCTGATCATCGATGAGGATGAAAACGAGCATGACCACGAAGTGGAAGATGTGGATGACTACGAGGACGAGgaagatgaggaggaggacgagccAGAAGACGAGCCAGAGGTGATTCTAGACGAGCCGCATGACGTAACGGTCGTGGAAAAGGAGGAAGCgccagaggaggaggatgagctaCCCAAGCCCCTGGAGCAGCTTAGCACAATGTCCAAGTCCAGCCCCAGTCATAACGAGGCTGCCCAGAAGATGGCAGAGACCATCCTCGAACAGGCCATCAAGGCTGGCAAGCAGCCATCTGTGACTACGACTCCGCCGTCCGCTGCGGCTTCCTCTGTCCAGGAGGAGACTCCCCCAACAGCTGTAACGCCACCGACTGCCATGCAGGAGCCCAGCAGTAATCCCAGCAGCCTGAAGACCATGATAGCCCAGGCCGAGTCCGTTGGCAAGTCGCTCAAAGAGGTGGCCAGTTCGCCGTTCAAGGACGACTCCCAGGACTTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGTGCCAGCGagagcaacaacagcggcacAGAGGATgtcaccagctccagctcgagcAGCGAGCCAAAGAAGAAGTCCGCCTACAGCCTGGCCCCGAACCGCGTCTCCTGCCCATACTGCCAGCGCATGTTCCCGTGGAGCAGCTCATTGCGCCGCCACATCCTCACGCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACCAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAATGTCGAGTCCGCCATGTCGGTCTATGTGCCCACCGAGGATGTTAGCGAGCCGATACCGGTGCCCAAGTCAGTGGAGGAGatcgagctggaggagcagcgtcGCCGTCAGGAGGCGGAGCGCGAAAGGGAGCGTGAGCTGGAGCGCGAGCGGGAGATGGAGCGCGAGCGTGAGCTGGAGCGGGAGCgtgagctggagaaggagaaggagcgcgAACGTCAGCAGCTCATACATAAGCTGGCCGCCCAGATGAGTGCCGccgcggcagctgctgctgccgctgccgctgcctcatGTGCCTCGCCAGGCAATGGCTCGTctgccggagctggagctggtgccgTAGGCGATCTCTCAGCCGGTGGCGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGCCTGCAATGCCTGGAGCACATCAAGCAGACGCATGCCCATGAGTTcgccctgctgctggccaagggGGCCATTGAGAATGAGTCGCTGCACTCCGCCGACTCATCgaatccccagcagcagcagccacaacaccAACACTCGGATGATGAGGCCACCAATGGCCTGGGCCGTGGCAAATATCCGGATTACAGCAACCGCAAGGTCATCTGCGCCTTCTGCGTGCGCCGGTTCTGGTCCACCGAGGACCTAAGGCGCCACATGCGCACCCACTCCGGCGAGAGGCCCTTCCAGTGCGACATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGGGCCCACAATGGGGATACGCCCGGCTCCGATTGTTCCGATGATGAGCAGGCGATGAGCAGTCCGCCCGGCACTCCAGCTCCCTCTCCTATGCCGCTTCCCTCCagcgccaacaacaacaacagctgccagaataataacaacaacaacaataataataacagcaataacaataataataacaacaagctCGGCATGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGGGCAAGTCGATTGGGCGAGCACAAGGAGAACCTGGGCGAGGCAACCCCAtcgggagcagcggcagccggcTCGGATCTGATTGGTAACCTTTTGGGGATCAGCGATCAAGGCATACTCAACAAGCTGCTATCCTCCGCCGATGAGGCGGCCAAGCTCCTGGGCGTGGACAACAAGTGA
Protein Sequence
MLATQQQQQAQPGSSNNNNVAASAHTKMNSNNTDIAAEMERKRRESTTSESSLEHLDLGRTPKKLSGSAGAAQSTSTPHEVAVTSRKRKLRQLQQQHHQHHQQSRSDLLTDEDEDEDEARPLNRHKQRRGAAAQGSSSTAAIVVDYSAGDASSLRKKFRLNRSAASLSESGFVDASSTAHSGYLGNNSSSASTSLAVPSVPTSAAGGAAASASNSSSTSTSSNSSSIGGGSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAQSQSQSQSQAQLQRRQQQQQQQQQPTHPAQQQQQQPQQQTLASSLPVRAESYESDASCSTDVSSGNSRSRSSSSLHNNNNNSHKATNNNRSSKHELEELEEQDLEDNKQQLQRRLKTTINNNVIDAENPVEEDLHGEEEDADDVAMLTSTPDVATLLAGASASGAASRSPSPSPPGSPGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGSSLGVGLPPMLGASSSPLHADEDAEDEEEADHEDDEEMEQKRDDFFHKLYLKGSSGAAGGNGVGGIISHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGSVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADMSFRSISPTPPPPPPPVGESSSSQLKHMLLGEQQHHNHHHTVAPAQPPLKIQVKSLDQLVDKKPAPVQQPEKSSSALDFSMDVLDLSKKPTGAATTPTPTPTPSLTPAPLGASAVVAPAADLAAALEQQQLLLAQQQLFGGAGDAASQYMQQLFRSLVFQSQTPGFSFFPFMAPPPPEVNPEKPPLVSPPSRMNPLPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAVAMGPAGGSSHHHGHAHSHGHNHSHNHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLGPAPGAPHVSSQGNGQTPLTMDDDEPKLIIDEDENEHDHEVEDVDDYEDEEDEEEDEPEDEPEVILDEPHDVTVVEKEEAPEEEDELPKPLEQLSTMSKSSPSHNEAAQKMAETILEQAIKAGKQPSVTTTPPSAAASSVQEETPPTAVTPPTAMQEPSSNPSSLKTMIAQAESVGKSLKEVASSPFKDDSQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELEREREMERERELERERELEKEKERERQQLIHKLAAQMSAAAAAAAAAAAASCASPGNGSSAGAGAGAVGDLSAGGDLPYKCHLCEGSFAERLQCLEHIKQTHAHEFALLLAKGAIENESLHSADSSNPQQQQPQHQHSDDEATNGLGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQAMSSPPGTPAPSPMPLPSSANNNNSCQNNNNNNNNNNSNNNNNNNKLGMKLPKLHELLDKANEWRASRLGEHKENLGEATPSGAAAAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK