Basic Information

Insect: Drosophila serrata
Gene Symbol: RREB1
Assembly: GCA_002093755.1
Location: NW:828485-838400[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.03 2 8.8 0.8 1 21 265 285 265 287 0.93

2 12 0.00028 0.018 15.1 0.2 1 23 297 319 297 319 0.98

3 12 6.9e-05 0.0045 17.1 7.3 1 23 325 347 325 347 0.98

4 12 1.8 1.2e+02 3.2 3.7 2 19 565 582 565 584 0.97

5 12 0.0071 0.46 10.7 0.1 1 23 732 754 732 754 0.97

6 12 1e-05 0.00068 19.7 0.7 1 23 764 786 764 786 0.99

7 12 0.00071 0.046 13.9 2.0 1 23 792 815 792 815 0.97

8 12 0.0025 0.16 12.2 2.0 1 23 1083 1106 1083 1106 0.95

9 12 7.3e-05 0.0048 17.0 0.3 2 23 1497 1518 1496 1518 0.97

10 12 0.12 8 6.8 6.3 1 23 1524 1547 1524 1547 0.97

11 12 0.0072 0.46 10.7 0.5 3 23 1756 1776 1754 1776 0.96

12 12 0.01 0.66 10.2 6.1 1 23 1782 1804 1782 1804 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.03	2	8.8	0.8	1	21	265	285	265	287	0.93
2	12	0.00028	0.018	15.1	0.2	1	23	297	319	297	319	0.98
3	12	6.9e-05	0.0045	17.1	7.3	1	23	325	347	325	347	0.98
4	12	1.8	1.2e+02	3.2	3.7	2	19	565	582	565	584	0.97
5	12	0.0071	0.46	10.7	0.1	1	23	732	754	732	754	0.97
6	12	1e-05	0.00068	19.7	0.7	1	23	764	786	764	786	0.99
7	12	0.00071	0.046	13.9	2.0	1	23	792	815	792	815	0.97
8	12	0.0025	0.16	12.2	2.0	1	23	1083	1106	1083	1106	0.95
9	12	7.3e-05	0.0048	17.0	0.3	2	23	1497	1518	1496	1518	0.97
10	12	0.12	8	6.8	6.3	1	23	1524	1547	1524	1547	0.97
11	12	0.0072	0.46	10.7	0.5	3	23	1756	1776	1754	1776	0.96
12	12	0.01	0.66	10.2	6.1	1	23	1782	1804	1782	1804	0.99

Sequence Information

Coding Sequence: ATGCTCGCgacacagcaacaacaacaaccacagcccggcaacagcagcagcagcagcagcagcagcaacaacagcaataacaTAGCCGCCGCCACTCACACAAAGAtgaacagcaacaccaacacagACATTGTTGTGGAGATGGAGCGGAAGCGAAGAGAGTCGACAACATCAGAATCCTCTCTCGAGCATCTCGACCTCGGTCGTACGCCAAAGAAGCTCAGCGGCAGCGCCGGTGCCGCTCAGTCGACATCGACGCCACACGAGGTGGCAGCGACGTCGCGCAAGCGTAAGCTGCgtcagctgcagcagcagcaccaccttCAGCAAAGTCGATCGGATCTTCTCACTgatgaggacgaggatgaggatgaagcACGTCCCCTGAATCGGCACAAGCAGCGACGCGGTGCCGCCGGTCAGggatcctcctcctccgcctccgcctccatTGTGGTGGACTACTCTGCCGGCGATGCCAGTTCGCTGCGCAAAAAGTTCCGTCTCAATCGCTCGGCAGCGAGTCTCTCGGAATCGGGATTCGTGGACGCCAGCAGCACTGCCCACAGTGGCTATCTGGGGAACAATAGCAGCAGCGCCAGCACAAGTCTGGCAGTGCCCACTGTTCCCGCATCTGCCGTCGGTGGAGCAGCGGCCTCAGCGTCGAGTAGCAGCACCAGCTCCAGCAGTAATAGCAGCAGCATTGGCGGCGGTTCCGGTGGCTCCTCACCGCAGGGTCTGTGCCTCTCCAGCGGCGAGTCGGGCATCGGTGCGGGTGATGAGCATATGAAATACCTGTGCCCCATCTGCGAGGTGGTCTCTGCCACGCCGCACGAGTTCACCAATCACATTCGATGCCACAACTATGCTAATGGAGACACGGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGTTATCTTCTGCCTCATCTCTGGACAGGCACGTGCTAGTGCATACGGGCGAGCGGCCGTTCAACTGTCGCTACTGCCACCTGACCTTCACCACCAACGGCAATATGCATCGTCATATGCGCACTCACAAGCAGCACCAGACGGTGcagtcccagtcccaatcCCAGTCTCAAGCCCAGCTGCAGCGCcgtcaacagcagcagcaacagcaacagcagcagcagcagacacatcccgcccagcagcagcaacagcagcagacgCTGGCCAGCAGCTCCTTGCCCGTACGGGCGGAGAGCTATGAAAGCGATGCCAGCTGCTCCACGGATGTGTCCAGCGGTAATagtcgcagtcgcagcagTAGCTCCCttcacaacaacaacaacaactcccACAAGgcaaccaacaacaacaggaacAGCAAGCATGAGCTGGATGAGTTGGAGGAGCAAGAGCTGGAGGATAAcaagcagcaactgcaacgtCGTCTAAAAACAACCATCAACAACAATGTCATCGATGCGGAGAATCATGCGGAGGAGGATCTGCACGGCGAGGAGGAGGACGCAGATGATGTGGCCATGCTCACAAGCACACCCGATGTGGCCACATTGCTGGCAGGAGCCAGTGCCTCTGGTGCTGCCTCCCGTTCACCCTCACCCTCGCCACCCGGCTCACCTGGCCTGCTCCTGAGTTGTCCCGCCTGCGGAGCCTCTGATTTCGAAACCCTGCCTGCTCTGTGCGCCCATCTGGATGCCCGGCATTCCGATATACCGGCCAAGTGTCGGGATTGTGAGGTGATCTTTGCAAGCCACCGCCAGTTGCAGGCACACTGCTGCAGGGGATCCTCTTTGGGAGTGGGACTGCCGCCTATGCTGGGCGCCAGCAGTTCGCCGCTGCATGCCGATGAGGATGCCGAAgatgaggaggaggcggaTCACGAAGATGATGAGGAAATGGAGCAAAAGCGTGATGATTTCTTCCACAAGCTGTACCTCAAGGGAACATCGGGTGCAGCGGGTGGCAACGGTGTTGGCGGCATTATCTCTCACCCGCCGTCCCCAATTAAGCACGAGCCGGCGGATAGCAAGGATCTGGCCGATATACAGAGTATCCTGAACATGACCAGCTCCAGCTGCACCAGCAGCTTTCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAATACAGTTTGGATGGGCGTgatcaggaggaggaggcccaGGATGCCTTCACCTCGGAATTCCGCCGGATGAAGCTGCGCGGTGAGTTCCCCTGCAAGCTTTGCACTGCTGTTTTTCCGAATCTACGGGCTCTCAAGGGTCACAACCGGGTTCACCTTGGTTCGGTTGGACCTGCGGGACCCTTCCGTTGCAACATGTGTCCTTACGCCGTCTGCGATAAGGCGGCTCTGGTGCGCCACATGCGAACTCACAATGGTGACCGTCCGTACGAGTGTGCCGTCTGCAACTATGCCTTCACCACCAAGGCCAACTGTGAGCGCCATTTGAGGAATCGGCATGGCAAGACCAGCCGCGAGGAGGTTAAGCGTGCCATCGTCTACCATCCGGCCGAGGACGCCGGCTGTGAGGACAGCAAGTCGCGTCTGGGTGAGGATCTGGCTGATATGAGCTTCCGCTCTATAAGTCCaacgccgccaccaccaccgccaccaaTTGCTGAGAGCAGCAGCTCCCAGCTGAAGCACATGCTCTTGGgcgagcagcagcatcataatcatcatcatcccgTGGCACCAGCTCAGCCGCCGTTAAAGATTCAGGTAAAGAGCCTGGACCAACTGGTGGACAAGAAACCGACGACAGTTCAACAGCCGGAGAAGAGCTCCTCTGCCTTGGACTTTAGCATGGATGTGTTGGATCTCAGCAAGAAGCCAACGGGTGCAGCAACTACACCCACACCTACCCCTACGCCCTCACTCACGCCAGCACCCCTCGGTGCGCCTGCAGTGGTCACTCCGACTGCCGACCTGGCCGCCGCTTTGGAGCAACAGCAATTGCTCCTGGCACAGCAGCAACTCTTTGGCGGTGCCGGTGACGCCTCCCAGTACATGCAGCAGTTGTTCCGCAGCCTTATGTTCCAGTCCCAGACGCCGGGCTTCTCCTTCTTCCCATTCATGGCGCCACCGCCGCCGGAGGTGAATCAAGAGAAGCCGCCACTGGTGAGTCCTCCATCCCGGATGAACCCATTGCCCGTGGGCGTTGGTGTGCCAGTGCCGCCCGGCGGACCCGTCAAAATGGTCATCAAGAACGGTGTGCTGATGCCCAAGCAGAAGCAGCGTCGCTATCGCACCGAACGTCCCTTCGCCTGCGAGCACTGCTCCGCCCGGTTCACGCTGCGTTCCAATATGGAGCGACATGTGAAGCAACAGCATCCACAGTTCTATGCCCAGCGACAGCGCAGTGGTCACCATGTGATGAGGGGCAGAGGAGCGTCGaatgccgccgctgctgctgctgccgctgccgctgcagcGGTTGCCATGGGTCCAGCTGGAGGATCATCCCATCATCATGGTCACACCCACACTCACGGCCACAATCACAGTCACAACCATGGCCATGGACATGGTCATGCTCCCATCTCCGAGCAGGTGAAATATGCCATTTTGGCGCAGCAGCTGAAGGCGCACAAGAACACCGATCTTCTGCAGCAGGCCTTGGCCCATGGCTCTAGCAGTGTGGCGGGCAATCCCCTCCTGCACTTTGGCTATCCACTGGGCCCTGCGCCTGGTGCTTCGCTTGTGAGCAGTCAGGGAAACGGGCAGACGCCCATGACCATTGACGATGATGAGCCCAAACTGATCATCGATGAGGATGAGAACGAGCATGACCATGAAGGGGAGCCGGAAGATGTGGATGACTACGAGGACGAGgaagatgaggaggaggacgagcCCGAAGATGAGCCGGAGGTGATTCTAGACGAACCGCAAGACGTAGCTGTCGTGGAAAAGGAGGAAGcgccggaggaggaggaagaggatgAGCTACCCAAGCCCCTGGAGCAGCTTAGCACAATGTCCAACTCCAACCCCAGTCAAAACGAGGCTGCCCAGAAGATGGCAGAGACCATCCTGGAGCAGGCCATCAAGGCTGGCAAGCAGCCAGCTGCGACTTCGACTCCGCCGTCCGATGCGGCTTCTTCGGTTCAGGAGGAGAATCCTCCAACAGCTGTAACTCCACCTGCTGCCATGCAGGAACCCAGCAGTAATCCCAGCAGCCTGAAGACCATGATTGCACAGGCCGAATCCGTTGGCAAGTCGTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGACGATTCACAGGACTTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCCAGAATATGAGTTTCAACAGCTACTTCCGGCCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCTGGCAGTGCCAGCGAGAGCAACAACAGCGGCACAGAGGATGTCACCAGCTCCAGTTCGAGCAGCGAGCCAAAGAAGAAGTCCGCCTACAGTCTGGCCCCGAATCGCGTCTCCTGTCCATACTGTCAGCGCATGTTCCCGTGGAGCAGCTCCTTGCGCCGCCACATCCTCACCCACACCGGTCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACCAAGAGCAACTGCGATCGGCATCTGTTGCGCAAGCATGGTAATGTCGAGTCCGCCATGTCGGTCTATGTGCCCACCGAGGATGTTAGTGAGCCGATACCAGTGCCCAAGTCCGTGGAGGAGATCGAACTGGAGGAGCAGCGTCGTCGCCAGGAAGCGGAGCGCGAAAGAGAGCGTGAACTGGAGCGCGAACGGGAGCTAGAGCGCGAACGTGAACTGGAACGGGAACGTGAactggagaaggagaaggagcgaGAACGACAGCAGCTCATCCATAAGCTGGCCGCCCAGATGAGtgccgctgcagcagctgctgcggcCGCTGCCGCTGTCTCATGTGCCTCGCCGGGTAATGGATCCTCGGCCggagctggagttggagcCGGAGGTGATCTTTCGGCCGGCGGTGATCTGCCCTACAAGTGCCACTTGTGCGAGGGCTCCTTTGCCGAGCGCCTGCAATGCCTGGAGCACATCAAGCAGACGCATGCCCATGAGTTTGCCCTGCTTCTGGCCAAGGGAGCCATTGAGAATGAGTCGCTGCACTCCACCGACTCATCAAacacccagcagcagcagtcacaGCACCAACACTCGGACGATGAGGCCACCAATGGCCTGGGCCGTGGCAAATATCCGGATTATAGCAACCGTAAGGTCATCTGCGCCTTCTGTGTGCGCCGGTTCTGGTCCACCGAGGATCTACGGCGCCACATGCGCACCCATTCCGGCGAGAGGCCCTTCCAGTGCGACTTCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGGGCCCACAATGGCTCCGATTGTTCCGACGATGAGCAGGCATTGAGCAGTCCGCCTGGTACACCAGCTCCCTCTCCAATGCCGCTTCCCTCCAGCgccaataacaacaacagctgccagaataataacaacaataataataataataatagcaataataataataacaataacaacaataagcTCGGCATGAAGCTACCCAAGCTGCACGAGCTACTGGACAAGGCGAACGAGTGGCGAGCGAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCAACCCCATCGGGAGCAGCGGCAGCCGGTTCGGATCTGATTGGAAACCTTTTGGGGATCAGCGATCAAGGCATACTCAACAAGCTGCTGTCCTCCGCCGATGAGGCGGCCAAGCTTCTGGGCGTGGACAACAAGTGA
Protein Sequence: MLATQQQQQPQPGNSSSSSSSSNNSNNIAAATHTKMNSNTNTDIVVEMERKRRESTTSESSLEHLDLGRTPKKLSGSAGAAQSTSTPHEVAATSRKRKLRQLQQQHHLQQSRSDLLTDEDEDEDEARPLNRHKQRRGAAGQGSSSSASASIVVDYSAGDASSLRKKFRLNRSAASLSESGFVDASSTAHSGYLGNNSSSASTSLAVPTVPASAVGGAAASASSSSTSSSSNSSSIGGGSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTVQSQSQSQSQAQLQRRQQQQQQQQQQQQTHPAQQQQQQQTLASSSLPVRAESYESDASCSTDVSSGNSRSRSSSSLHNNNNNSHKATNNNRNSKHELDELEEQELEDNKQQLQRRLKTTINNNVIDAENHAEEDLHGEEEDADDVAMLTSTPDVATLLAGASASGAASRSPSPSPPGSPGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGSSLGVGLPPMLGASSSPLHADEDAEDEEEADHEDDEEMEQKRDDFFHKLYLKGTSGAAGGNGVGGIISHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGSVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADMSFRSISPTPPPPPPPIAESSSSQLKHMLLGEQQHHNHHHPVAPAQPPLKIQVKSLDQLVDKKPTTVQQPEKSSSALDFSMDVLDLSKKPTGAATTPTPTPTPSLTPAPLGAPAVVTPTADLAAALEQQQLLLAQQQLFGGAGDASQYMQQLFRSLMFQSQTPGFSFFPFMAPPPPEVNQEKPPLVSPPSRMNPLPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAVAMGPAGGSSHHHGHTHTHGHNHSHNHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLGPAPGASLVSSQGNGQTPMTIDDDEPKLIIDEDENEHDHEGEPEDVDDYEDEEDEEEDEPEDEPEVILDEPQDVAVVEKEEAPEEEEEDELPKPLEQLSTMSNSNPSQNEAAQKMAETILEQAIKAGKQPAATSTPPSDAASSVQEENPPTAVTPPAAMQEPSSNPSSLKTMIAQAESVGKSLKEVASSPFKDDSQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERERELERERELERERELEKEKERERQQLIHKLAAQMSAAAAAAAAAAAVSCASPGNGSSAGAGVGAGGDLSAGGDLPYKCHLCEGSFAERLQCLEHIKQTHAHEFALLLAKGAIENESLHSTDSSNTQQQQSQHQHSDDEATNGLGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDFCLRKFTLKHSMLRHMKKHSGRAHNGSDCSDDEQALSSPPGTPAPSPMPLPSSANNNNSCQNNNNNNNNNNSNNNNNNNNNKLGMKLPKLHELLDKANEWRASRLGEHKENLGEATPSGAAAAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491706;
90% Identity: iTF_00491706;
80% Identity: -