Basic Information

Insect: Drosophila nikananu
Gene Symbol: RREB1
Assembly: GCA_008042635.1
Location: VNJV01016638.1:84022-90233[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.031 3.5 8.7 0.8 1 21 263 283 263 285 0.93

2 12 0.00029 0.032 15.1 0.2 1 23 295 317 295 317 0.98

3 12 6.9e-05 0.0078 17.0 7.3 1 23 323 345 323 345 0.98

4 12 1.8 2e+02 3.1 3.7 2 19 581 598 581 600 0.97

5 12 0.0075 0.85 10.6 0.1 1 23 750 772 750 772 0.97

6 12 1.1e-05 0.0012 19.6 0.7 1 23 782 804 782 804 0.99

7 12 0.00071 0.08 13.8 2.0 1 23 810 833 810 833 0.97

8 12 0.0025 0.29 12.1 2.0 1 23 1128 1151 1128 1151 0.95

9 12 7.4e-05 0.0083 16.9 0.3 2 23 1549 1570 1548 1570 0.97

10 12 0.12 14 6.8 6.3 1 23 1576 1599 1576 1599 0.97

11 12 0.0072 0.81 10.7 0.5 3 23 1817 1837 1815 1837 0.96

12 12 0.0012 0.13 13.1 4.8 1 23 1843 1865 1843 1865 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.031	3.5	8.7	0.8	1	21	263	283	263	285	0.93
2	12	0.00029	0.032	15.1	0.2	1	23	295	317	295	317	0.98
3	12	6.9e-05	0.0078	17.0	7.3	1	23	323	345	323	345	0.98
4	12	1.8	2e+02	3.1	3.7	2	19	581	598	581	600	0.97
5	12	0.0075	0.85	10.6	0.1	1	23	750	772	750	772	0.97
6	12	1.1e-05	0.0012	19.6	0.7	1	23	782	804	782	804	0.99
7	12	0.00071	0.08	13.8	2.0	1	23	810	833	810	833	0.97
8	12	0.0025	0.29	12.1	2.0	1	23	1128	1151	1128	1151	0.95
9	12	7.4e-05	0.0083	16.9	0.3	2	23	1549	1570	1548	1570	0.97
10	12	0.12	14	6.8	6.3	1	23	1576	1599	1576	1599	0.97
11	12	0.0072	0.81	10.7	0.5	3	23	1817	1837	1815	1837	0.96
12	12	0.0012	0.13	13.1	4.8	1	23	1843	1865	1843	1865	0.99

Sequence Information

Coding Sequence: ATGCTCGCGactcagcagcaacaacaacaaccgcagcccggcaacagcagcagcaacaacaataacatagccgccgccgccacacacacaatgatgaacagcaacaacacagaCTTGGTAGAGATGGAGCGTAAGCGAAGAGAGTCCACAACATCAGAATCCTCTCTCGAGCATCTCGACCTGGGACGAACGCCAAAGAAGCTCAGCGGCAGCGCCGGTGCTGCGCAGTCGACATCGACGCCGCACGAGGTGGCGGCAGCGACGTCGCGCAAGCGCAAGCTGcgccagctgcagcagcaccaccagcagagTCGTTCGGATCTCCTTAGcgatgaggacgaggacgaggaggaggaggaggaggcacgTCCCCTCAATCGGCACAAACAGCGACGAGGCGCCCAgggttcctcctcctccgcatCCGCCTCCATTGTGGTGGACTACTCCGCCGGTGATGCCAGTTCGCTGCGCAAAAAGTTCCGTCTCAATCGCTCGGCGGCGGCCAGTCTCTCGGAATCGGGATTCGTGGATGCCAGCAGCACTGCCCACAGTGGCTATCTGGGCAACAatagcagcagcgccagcacaAGCCTGGCAGTGCCTTCAGTTGCCACAACCGGTGCCGCCGGTGGAGCAGCTcccgccgcctccgcctccgcctctgcctcgagcagcagcaccagcacaaGCAGCCACCACAGCAGCTCCGGTGGCTCCTCCCCGCAGAACCTGTGCCTCTCCAGCGGCGAGTCTGGCATTGGGGCCGGCGATGAGCACATGAAATACCTGTGTCCCATCTGCGAGGTGGTTTCCGCCACGCCGCACGAGTTCACCAATCACATTCGCTGCCACAACTATGCCAATGGGGATACGGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGTTATCTTCGGCCTCATCCCTGGACAGGCACGTGCTGGTTCATACGGGCGAGCGGCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAATGGCAATATGCATCGCCATATGCGCACTCACAAGCAGCACCAGACAGCTCAGtcccagtcgcagtcgcagtcgcagtcccagtcccagtctcAAAACCAAACCCAGCTGCAGCgccgtcagcagcagcagcagcaccaccaccaccagcaccagcagcagcagaatcatcccgcccagcagcagcagcaggctcagCAACAGACTCTCGCCAGCTCCATGCCAGTGCGGGCGGAGAGCTATGAAAGCGATGCCAGCTGCTCCACGGATGTGTCCAGCGGTAATAGTCACAGTCGCAGCAGTAGCTTTcttcacaacaacaacaacaactcccACAAGGctaccaacaacaacaacaacagcaagcgggagctggagggattggaggagcaggagcacgaGCACGAGCTGGAGGACAACAAGCAGCTGTTACAGCGTCGCCTGAAGACGACCATTAACAACAATGTGATCGAGAACCATGCGGATGAGGAGGATCTTCATAACGAGGAAATGGAGGATGCTGATGCGGATGTGGCCATGCTCACAAGCACTCCGGATGTCGCCACACTGCTGGCAGGAGCCAGTGCCTCCGGTGCTGCCTCACGTtcgccctcgccctcgccACCGGGCTCGCCCGGCGGCTTGCTACTGAGTTGCCCCGCCTGCGGAGCCCCCGATTTCGATAACCTGCCTGCTCTGTGCGCCCATCTGGATGCCCGGCATTCCGATATACCGGCCAAGTGCCGGGACTGTGAGGTGATCTTTGCCAGCCATCGCCAGCTGCAGGCACACTGCTGCAGGGGAGGATCTGCATTGGGCGTGGGTCTGCCGCCCATGCTGGGCGCCAGCAGTTCGCCGCTGCATGCCGGATGCGAGGAtgccgaggacgaggaggaggaggacgaggcgGATCATGAAGATGATGAGGAGATGGAGCAAAAACGTGATGACTTCTTCCACAAGCTGTACTTGAAGGGTACGACGGGTGGAGTGGGTGCAGCGGGCAATATCTCCCATCCGCCATCGCCCATCAAGCACGAGCCGGCGGACAGCAAGGATTTGGCCGATATACAAAGCATCCTGAACATgaccagctccagctgcacCAGCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAATACAGCCTGGATGGGCGcgaccaggaggaggaggcccagGATGCCTTCACCTCGGAATTCCGACGGATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCGGCTGTCTTTCCGAATCTACGCGCCCTCAAGGGTCACAATCGGGTGCATCTCGGTGCGGTTGGCCCCGCCGGTCCGTTTCGCTGCAACATGTGTCCCTACGCCGTCTGCGACAAGGCAGCCCTCGTGCGGCACATGCGCACCCACAACGGTGACCGGCCGTACGAGTGCGCCGTCTGCAATTATGCCTTCACCACAAAGGCCAACTGTGAGCGCCACCTGAGGAATCGGCACGGCAAGACCAGTCGCGAGGAGGTGAAGCGAGCCATTGTCTACCATCCCGCCGAGGATGCTGGCTGCGAGGATAGCAAGTCCAGGCTGGGTGAGGATCTGGCCGATATGAGTTTCCGCTCAATAAGTCccacgccgccgccaccgccaccaccgctGCCGCCAGTGGGTgagggcagcagcaacagcagcagcagcagctcccagCTGAAGCACATGCTCCTGGGCGAGCAACAGCATCatcattcccattcccattcccattcccatcaccatcaccatacGGTGGCCCTAGTTCAGCCGCCGTTAAAGATCCAGGTGAAGAGCCTGGACCAGCTGGTAGACAAGAAACCAGCGGCAGTTCAACAGCCGGAGAAGAGCTCCTCGTCTGCCCTGGACTTTAGCATGGATGTGTTGGATCTCAGCAAGAAGCCAACGGGTGCAGCCGCCATcacgcccacacacacgcccTCCTCGCTCACGCCGGCGCCAGCCCACGTCGGTGCGTCGTCGTCTGCTGTGGTTGCTGCTCCGTCTGCCGATCTGGCCGCCGCTCTGGAACAACAGCAATTGCTACTGGCACAGCAGCAACTCTTTGGCGGTGCCGGTGATGCTGCCTCCCAGTACATGCAGCAGCTGTTCCGCAGCCTGGTGTTCCAGTCCCAGACGCCGGGCTTTTCCTTCTTCCCGTTCATggcaccaccgccgccggagGTCAACCAAGAGAAGCCGCCTCTGGTGAGTCCACCATCGCGTATTAACCCACTGCCCGTGGGCATGGGCGTGGGTGTGCCCGTGCCGCCCGGTGGACCCGTCAAAATGGTCATCAAGAATGGCGTGCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAACGTCCATTCGCCTGCGAGCATTGCTCCGCCCGGTTCACGCTGCGCTCCAACATGGAGCGACATGtgaagcagcagcatccgcagTTCTATGCCCAGCGACAGCGCAGCGGTCACCATGTTATGAGGGGCAGGGGCGCATCGaatgccgccgctgctgctgctgctgccgctgccgctgcggcggctgccatgGGTCCAACGGGGGGATCCGCCTCCCATCATCatcacagccacagccacagccacggTCACGGTCACAACCATGGACATGGTCATGGGCATGCTCCCATCTCCGAGCAGGTGAAGTACGCCATTTTGGCGCAGCAATTGAAGGCGCACAAGAACACCGATCTCCTGCAGCAGGCCTTGGCCCATGGCTCCAGCAGTGTGGCCGGGAATCCCCTCCTGCATTTTGGCTATCCGCTGGGCCCCGCACCAGGGGCTCCGCATGTGAGCAGCCAGGGTAACGGTCAGACGGCCATGGCCATGGACGATGATGAGCCCAAGCTGATCATCGATGAGGATGAAAATGAGCACGACCACGACCACGAAGTGGAGCCTGAGGATGTGGATGACTACGAGGATGAGgaagatgaggaggaggacgagccCGAAGATGAGCCGGAGGTGATTCTAGACGAACCGCATGTTGTTGTGGAAAAGGAGGAAGCtcccgaggaggaggaggaggatgagccACCCAAGCCCCTGGAGCAGCTTAGCGCAATGTCCAAATCCAGTCCAAGTCACAATGAGGCTGCCCAGAAGATGGCCGAGACCATACTGGAGCAGGCCATCAAGGCTGGCATCAAGCAgccttcatcatcatcatcatctgcaACGACCCCGGTGTCCGCCGCGGCGGCATCCTCCATCCAAGAGGAGAATCCTCCAGCAGCTGTAACCCCACCGGCTGCCATGCAGGAGCCCAGCAGTAATCCCAGCAGCCTAAAGACCATGATAGCCCAGGCCGAGTCTGTGGGCAAGTCGCTAAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCCCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGACCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGTGCCAGCGagagcaacaacagcggcacAGAGGATGtcaccagctccagctccagcagcgAGCCCAAAAAGAAGTCCGCCTACAGTCTGGCCCCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGCCGCCACATTCTCACCCATACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCATGGCAACGTCGAGTCCGCCATGTCGGTCTATGTGCCCACCGAGGATGTTAGCGAGCCGATACCGGTGCCCAAGTCCGTGGAGGAGAtcgagctggaggagcagcgtCGCCGCCAGGAGGCGGAGCGCGAAAGGGAGCGCGAACTGGAGCGTGAGCGTGAGCTGGAGCGAGAGCGTGAGCTGGAACGGGAGCGTgagctggagaaggagaaggagcgggagcgggagcgtcAGCAGCTTATCCATAAGCTGGCCGCCCAGATGAGTGCTGCcgctgcggcagcggcggctgctgctgcctcatGTGCCGCCTCATCGCCAGGCAATGGATCCTctgccggagccggagccggatcGGGTGGTGATCTTTCCGCCGGCGGCGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGTTTGCAATGCCTGGAGCATATCAAGCAGACGCATGCCCACGAGTTCGCCCTGCTCCTGGCCAAGGGGGCCATTGAGAATGAGTCGCTGCACTCCAACGACTCATCGaatccccagcagcagcagcagcagcaccagctgcAGCCACAACACCAGCACTCTGACGATGAGGCCACCAATGGCTTGGGCCGTGGCAAATATCCGGATTATAGCAATCGCAAGGTGATCTGCGCCTTCTGTGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGGCGTCACATGCGCACCCATTCCGGCGAGAGGCCCTTCCAGTGCGACATCTGCCTGCGCAAGTTCACCCTCAAGCACAGCATGCTGCGTCACATGAAGAAGCACAGTGGACGGGCCCACAATGGGGATACGCCCGGCTCCGATTGCTCGGACGATGAGCAGGCAATGAGCAGCAGTCCGCCGGGGACACCGGCTCCCTCGCCCATGCCCACGCTACCCTCCagcgccaacaacaacaacagctgccagaataataataataataataacaacaataccaataataacaataataataacaacaacaagctcGGCCTGAAGCTACCCAAGCTGCACGAGCTGCTGGACAAGGCCAATGAGTGGCGAGCGAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCAACGCCCTCGGGAGCAGCGGCCGCCGGTTCGGATCTGATTGGTAACCTACTGGGTATCAGTGATCAGGGCATACTCAACAAGCTGCTGTCCTCCGCCGATGAGGCGGCCAAGCTTCTGGGCGTGGACAACAAGTGA
Protein Sequence: MLATQQQQQQPQPGNSSSNNNNIAAAATHTMMNSNNTDLVEMERKRRESTTSESSLEHLDLGRTPKKLSGSAGAAQSTSTPHEVAAATSRKRKLRQLQQHHQQSRSDLLSDEDEDEEEEEEARPLNRHKQRRGAQGSSSSASASIVVDYSAGDASSLRKKFRLNRSAAASLSESGFVDASSTAHSGYLGNNSSSASTSLAVPSVATTGAAGGAAPAASASASASSSSTSTSSHHSSSGGSSPQNLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAQSQSQSQSQSQSQSQNQTQLQRRQQQQQHHHHQHQQQQNHPAQQQQQAQQQTLASSMPVRAESYESDASCSTDVSSGNSHSRSSSFLHNNNNNSHKATNNNNNSKRELEGLEEQEHEHELEDNKQLLQRRLKTTINNNVIENHADEEDLHNEEMEDADADVAMLTSTPDVATLLAGASASGAASRSPSPSPPGSPGGLLLSCPACGAPDFDNLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGGSALGVGLPPMLGASSSPLHAGCEDAEDEEEEDEADHEDDEEMEQKRDDFFHKLYLKGTTGGVGAAGNISHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADMSFRSISPTPPPPPPPLPPVGEGSSNSSSSSSQLKHMLLGEQQHHHSHSHSHSHHHHHTVALVQPPLKIQVKSLDQLVDKKPAAVQQPEKSSSSALDFSMDVLDLSKKPTGAAAITPTHTPSSLTPAPAHVGASSSAVVAAPSADLAAALEQQQLLLAQQQLFGGAGDAASQYMQQLFRSLVFQSQTPGFSFFPFMAPPPPEVNQEKPPLVSPPSRINPLPVGMGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAAAAMGPTGGSASHHHHSHSHSHGHGHNHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLGPAPGAPHVSSQGNGQTAMAMDDDEPKLIIDEDENEHDHDHEVEPEDVDDYEDEEDEEEDEPEDEPEVILDEPHVVVEKEEAPEEEEEDEPPKPLEQLSAMSKSSPSHNEAAQKMAETILEQAIKAGIKQPSSSSSSATTPVSAAAASSIQEENPPAAVTPPAAMQEPSSNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERERELERERELERERELEKEKERERERQQLIHKLAAQMSAAAAAAAAAAASCAASSPGNGSSAGAGAGSGGDLSAGGDLPYKCHLCEGSFAERLQCLEHIKQTHAHEFALLLAKGAIENESLHSNDSSNPQQQQQQHQLQPQHQHSDDEATNGLGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQAMSSSPPGTPAPSPMPTLPSSANNNNSCQNNNNNNNNNTNNNNNNNNNKLGLKLPKLHELLDKANEWRASRLGEHKENLGEATPSGAAAAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491706;
90% Identity: iTF_00485346;
80% Identity: -