Basic Information

Insect: Drosophila lacteicornis
Gene Symbol: RREB1
Assembly: GCA_008044355.1
Location: VNKF01004845.1:42405-49539[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.031 2.5 8.8 0.8 1 21 228 248 228 250 0.93

2 12 0.00029 0.024 15.2 0.2 1 23 260 282 260 282 0.98

3 12 6.9e-05 0.0057 17.1 7.3 1 23 288 310 288 310 0.98

4 12 1.8 1.5e+02 3.2 3.7 2 19 527 544 527 546 0.97

5 12 0.0072 0.59 10.8 0.1 1 23 686 708 686 708 0.97

6 12 1.1e-05 0.00087 19.7 0.7 1 23 718 740 718 740 0.99

7 12 0.00071 0.058 13.9 2.0 1 23 746 769 746 769 0.97

8 12 0.0026 0.21 12.2 2.0 1 23 1050 1073 1050 1073 0.95

9 12 7.4e-05 0.0061 17.0 0.3 2 23 1459 1480 1458 1480 0.97

10 12 0.12 10 6.9 6.3 1 23 1486 1509 1486 1509 0.97

11 12 0.0072 0.59 10.8 0.5 3 23 1714 1734 1712 1734 0.96

12 12 0.0012 0.098 13.2 4.8 1 23 1740 1762 1740 1762 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.031	2.5	8.8	0.8	1	21	228	248	228	250	0.93
2	12	0.00029	0.024	15.2	0.2	1	23	260	282	260	282	0.98
3	12	6.9e-05	0.0057	17.1	7.3	1	23	288	310	288	310	0.98
4	12	1.8	1.5e+02	3.2	3.7	2	19	527	544	527	546	0.97
5	12	0.0072	0.59	10.8	0.1	1	23	686	708	686	708	0.97
6	12	1.1e-05	0.00087	19.7	0.7	1	23	718	740	718	740	0.99
7	12	0.00071	0.058	13.9	2.0	1	23	746	769	746	769	0.97
8	12	0.0026	0.21	12.2	2.0	1	23	1050	1073	1050	1073	0.95
9	12	7.4e-05	0.0061	17.0	0.3	2	23	1459	1480	1458	1480	0.97
10	12	0.12	10	6.9	6.3	1	23	1486	1509	1486	1509	0.97
11	12	0.0072	0.59	10.8	0.5	3	23	1714	1734	1712	1734	0.96
12	12	0.0012	0.098	13.2	4.8	1	23	1740	1762	1740	1762	0.99

Sequence Information

Coding Sequence: ATGGAGCGGAAGCGGAGAGAGTCCACCACGTCCGAGTCCTCTCTCGAGCATCTCGACCTCGGCCGAACGCCAAAGAAGCTCAGCGGCAGCGCCGGCGCCGCGCAGTCGACATCGACGCCGCACGaggtggcggtggcagcgACGTCGCGCAAGCGCAAGCTGCGccaactgcagcagctgcagcagcagcagcaccaccaccaccaccaccagcagagCCAGGATCCCCTgagcgacgaggacgaggacgaggaggaggaggcggcccGGCCCCTCAGTCGCCACAAGCAGCGACGCGGCGCCGCCGCCACTCAGGgatcctcctccgcctccgcctccattGTGGTGGACTACTCCGCCGGCGACGCCAGCTCGCTGCGCAAAAAGTTCCGTCTCAACCGCTCGGCGGCCAGTCTCTCGGAGTCGGGATTCGTGGACGCCAGCAGCACCGCCCACAGTGGCTATCtgggcaacaacagcagcagtgccagtgccagtgccagtgccagcaCCAGCCTGGCCGTGCCTCCTGCCTCCACATCCGCCGGTGGGGGAGCAGCtgcctccagcagcagcaccagctcgagcagcaacagcagcaactccgGCGGCTCCTCGCCGCAGGGCCTGTGCCTCTCCAGCGGCGAGTCGGGCATCGGGGCGGGCGACGAGCACATGAAGTACCTCTGCCCCATCTGCGAGGTGGTCTCCGCCACCCCGCACGAGTTCACCAATCACATCCGGTGCCACAACTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTATCCTCGGCCTCATCCCTGGACAGGCACGTGCTGGTGCACACGGGCGAGCGGCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGCCACATGCGCACCCACAAGCAGCACCAGACGGCGCAGACCcactcccagtcccagtcccagacccagacccagacccaggcccagctgcagcgccgccagcagcagcagcagacgcatcccgcccagcagcagcagcagcagcagcagcagcaggcgctggCCAGCTCCATGCCCGTGCGGGCGGAGAGCTACGAGAGCGATGCCAGCTGCTCCACGGATGTCTCGAGCGGCaacagtcgcagtcgcagcagcagctccctccacaacaacaacaacaacaacaactcgcACAAGGCAACCaacaaggagctggagctggaggagctggagctggaggacaacaagcagcagctgcgacGCCTCAAGACGACCATCAACAACAACGTGATTGAGGCGGAGAACCAGGCGGCTGAGGAggaccaggaggaggaggaggaggccgacGATGCCGACGACGTGGCCATGCTCACCAGCACCCCCGATGTGGCCACGCTGCTGGCCGGAGCCAGTGCCTCTGGGGCAGCCTCCcgctcgccctcgccctcgccaCCGGGCTCACCCGCCGGCCTGCTCCTGAGCTGTCCCGCCTGCGGAGCCTCCGACTTCGAGACCCTGCCCTCGCTGTGCGCCCACCTGGACGCCCGGCACTCGGACATTCCAGCCAAGTGCCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGCTGCAGGCCCACTGCTGCCGGGGCTCCGGCCTGGGAGTGGGTCTGCCGCCCATGCTGGGCTCCAGCAGTTCGCCGCTGCACGGCGACGAGGAtgccgaggacgaggaggagcaggccgatggcgacgaggagctggagcagaagCGCGACGACTTCTTCCACAAGCTGTATCTCAAGGGAACCGCAGCGCCCAGCGGCATCTCGCATCCCCCGTCCCCCATCAAGCACGAGCCGGCGGACAGCAAGGATCTGGCCGACATCCAGAGCATCCTGAACAtgaccagctccagctgcaccAGCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTCGATGGGCGcgaccaggaggaggaggcccagGATGCCTTCACCTCCGAGTTCCGGCGGATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCACCGCCGTCTTTCCCAATCTCCGCGCCCTCAAGGGCCACAATCGGGTGCATCTTGGGGCCGTGGGTCCTGCGGGACCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGTGACAAGGCGGCGCTGGTGCGGCACATGCGGACCCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAATTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTGAGGAATCGCCATGGCAAGACCAGCCGCGAGGAGGTGAAGCGGGCCATTGTCTACCATCCGGCCGAGGATGCCGGCTGCGAGGACAGCAAGTCCCGTTTGGGCGAGGATCTGGCCGATCTGAGCTTCCGCTCCATCAGTCCCACACCGCCGCCTCCCCCAACGCTGGCCGAGagcggaggcagcagcagctcctcctcccagCTGAAGCACATGCTCATgggcgagcagcagcagcagcagcagcagcatcaccactCCGTGGCTCCTGCCCCCCAGCCGCCGCTCAAGATCCAGGTGAAGAGCCTGGACCAGCTGGTGGACAAGAAGCCAgctccccagcagcagcagcagccggcagtCTCGGAGAAGAGCTCCTCCGCCCTGGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACGGGTAGCActcccacgcccacgccggcTCCTCCAGCGGTCCAGGCGGCTGCCTTGCCTGCACCCGCGCCCGCTGCCGACCTGGCCGCCGCcttggagcagcagcacctgctcctggcccagcagcagctctttGGCGGCGTTGGGGGCGATGCGGCCTCCCAGTACATGCAGCAGCTATTCCGCAGCCTCGTGTTCCAGTCCCAGACGCCGGGCTTCTCCTTCTTCCCCTTCATGGCACCACCGCcgccccagcagcaggcgaATCCAGAGAAGCAGCCGCCCCTGGTGAGTCCACCCTCGCGGATGAACCCTTTGcccgtgggcgtgggcgttcCAGTTCCCCCTGGCGGCCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGccgaagcagaagcagcgtCGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCCCGGTTCACGCTCCGCTCCAACATGGAGCGCCACgtgaagcagcagcatccccAGTTCTATGCCCAGCGCCAGCGCAGTGGCCACCATGTGATGCGGGGCAGAGGTGCCTCCAATgcggccgctgccgctgctgctgccgccgccgctgctgcggctgccatGGGTCCCGGCGGAGGAGGTTCCTCCCATCATCATGCTCATGCCCACAGTCATGGTCACAGCCATGGCCATGGTCATGGACACGGACACGCTCCCATCTCGGAGCAGGTAAAGTACGCCATTTTGGCGCAGCAGCTGAAGGCGCACAAGAACACCGATCTCCTGCAACAGGCATTGGCCCATGGCTCCAGCAGCGTGGCGGGGAATCCCCTCCTGCACTTTGGCTACCCTTTGGGCCCGGCTCCGGGCGCACCTCTGGTGAGTGGCCCGGGAAACGGGGCCACGCCCATGGCCATCGACGATGATGAGCCCAAGCTGGTGATCGATGAGGATGAGAACGACCATGAGCACGATGTGGAGCCCGAGGATGTGGATGActacgaggacgaggaggatgaggaggaggacgacgccGAGGATGAGCCCGAGGTGATCCTAGACGAGCCTCACACGGTGGTCGTAGAGAAGGAGGAGCCCCCGGAGGAGGCAGAGGAGGATGagcgcgaggaggaggagctgccccAGCCACTGGAGCAGCTCAGGGCCAGTCCCGGCCAGAACGAGGCGGCCCAGAAGATGGCGGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCAGCAGCCCTCGCCATCCGCTGTCGTCGCCATCCCGGAGGAGCATCCCCCTACGGTGGCCACTCCTCCTTTGGCCATGCAGGAGCCCAGCAGCAATCCGAGCAGCCTGAAGACCATGATCGCCCAGGCCGAGTCCGTGGGCAAGTCCCTCAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAGTCACAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGTGCCAGCGagagcaacaacagcggcacCGAGGACGtgaccagctccagctccagcagcgaGCCCAAGAAGAAGTCCGCCTACAGCCTTGCACCCAATCGCGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGCCGCCACATTCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCTTGCTCTTCACCACCAAGAGCAACTGCGATCGCCATTTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTTTACGTGCCCACCGAGGACGTCAGCGAGCCCATCCCGGTGCCCAAGTCCGTGGAGGAGatcgagctggaggagcagcgtCGCCGCCAGGAGGCCGAGCGGGAGAGGGAGCGTGAactggagcgggagcgggaactGGAGCGTGAGCGCGagctggagcgggagcgggagctggagaaggagaaggagcgcgAGCGCCAGCAGCTCATCCACAAGCTGGCCGCCCAGAtgagcgccgccgccgcggccGCCGTCTCCGCTGCCTCGTGTGCCGGCTCCCCAGGGAATGGtggtggctcctcctcctcggatCCCTCGGCTGGTGGGGATTTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGGCTGCAGTGCCTGGAGCACATCAAGCAGACGCACGCCCACGAGTTCGCCCTGCTCCTGGCCAAGGGCGCCATCGAGAACGAGTCCCTGCACGCCGACACCTCGAATCCCCAgctggggcagcagcagcagcaccagcaacactCGGACGACGAGGCCACCAATGGGTGCCTGGGACGGGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGCCGCCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGACATCTGTCTGCGCAAGTTCACCCTGAAGCACAGCATGCTCCGTCACATGAAGAAGCACAGTGGCCGGGCCCACAATGGGGATACGCCCGGCTCCGATTGCTCCGACGACGAGCAGGCCATGAGCAGTCCCCCGGGCACGCCAGCGCCCTCGCCCATGCCCCTACCCTCCAACAACAGCTGCcagaacaataataataataataacaacaataataacaacaataataataataataataataataagctgGGCCTGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCCAACGAGTGGCGGGCAAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCCACGCCCTCGGGAGCAGCGGCCGCGGGCTCGGATCTGATCGGGAATCTGCTGGGGATCAGCGACCAGGGCATACTCAACAAGCTGCTGTCCTCGGCCGACGAGGCGGCCAAGCTCCTGGGCGTGGACAACAAGTGA
Protein Sequence: MERKRRESTTSESSLEHLDLGRTPKKLSGSAGAAQSTSTPHEVAVAATSRKRKLRQLQQLQQQQHHHHHHQQSQDPLSDEDEDEEEEAARPLSRHKQRRGAAATQGSSSASASIVVDYSAGDASSLRKKFRLNRSAASLSESGFVDASSTAHSGYLGNNSSSASASASASTSLAVPPASTSAGGGAAASSSSTSSSSNSSNSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAQTHSQSQSQTQTQTQAQLQRRQQQQQTHPAQQQQQQQQQQALASSMPVRAESYESDASCSTDVSSGNSRSRSSSSLHNNNNNNNSHKATNKELELEELELEDNKQQLRRLKTTINNNVIEAENQAAEEDQEEEEEADDADDVAMLTSTPDVATLLAGASASGAASRSPSPSPPGSPAGLLLSCPACGASDFETLPSLCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGSGLGVGLPPMLGSSSSPLHGDEDAEDEEEQADGDEELEQKRDDFFHKLYLKGTAAPSGISHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADLSFRSISPTPPPPPTLAESGGSSSSSSQLKHMLMGEQQQQQQQHHHSVAPAPQPPLKIQVKSLDQLVDKKPAPQQQQQPAVSEKSSSALDFSMDVLDLSKKPTGSTPTPTPAPPAVQAAALPAPAPAADLAAALEQQHLLLAQQQLFGGVGGDAASQYMQQLFRSLVFQSQTPGFSFFPFMAPPPPQQQANPEKQPPLVSPPSRMNPLPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAAAAMGPGGGGSSHHHAHAHSHGHSHGHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLGPAPGAPLVSGPGNGATPMAIDDDEPKLVIDEDENDHEHDVEPEDVDDYEDEEDEEEDDAEDEPEVILDEPHTVVVEKEEPPEEAEEDEREEEELPQPLEQLRASPGQNEAAQKMAETILEQAIKAGKQQPSPSAVVAIPEEHPPTVATPPLAMQEPSSNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERERELERERELERERELEKEKERERQQLIHKLAAQMSAAAAAAVSAASCAGSPGNGGGSSSSDPSAGGDLPYKCHLCEGSFAERLQCLEHIKQTHAHEFALLLAKGAIENESLHADTSNPQLGQQQQHQQHSDDEATNGCLGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQAMSSPPGTPAPSPMPLPSNNSCQNNNNNNNNNNNNNNNNNNNNKLGLKLPKLHELLDKANEWRASRLGEHKENLGEATPSGAAAAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491706;
90% Identity: iTF_00606533; iTF_00480363; iTF_00483165;
80% Identity: -