Basic Information

Insect: Drosophila leontia
Gene Symbol: RREB1
Assembly: GCA_008042735.1
Location: VNKB01015413.1:28931-36025[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.03 2.6 8.8 0.8 1 21 250 270 250 272 0.93

2 12 0.00028 0.024 15.2 0.2 1 23 282 304 282 304 0.98

3 12 6.8e-05 0.0058 17.1 7.3 1 23 310 332 310 332 0.98

4 12 1.8 1.5e+02 3.2 3.7 2 19 549 566 549 568 0.97

5 12 0.007 0.6 10.8 0.1 1 23 715 737 715 737 0.97

6 12 1e-05 0.00089 19.7 0.7 1 23 747 769 747 769 0.99

7 12 0.0007 0.06 13.9 2.0 1 23 775 798 775 798 0.97

8 12 0.0025 0.21 12.2 2.0 1 23 1074 1097 1074 1097 0.95

9 12 7.3e-05 0.0062 17.0 0.3 2 23 1481 1502 1480 1502 0.97

10 12 0.12 10 6.9 6.3 1 23 1508 1531 1508 1531 0.97

11 12 0.0071 0.61 10.7 0.5 3 23 1732 1752 1730 1752 0.96

12 12 0.0012 0.1 13.2 4.8 1 23 1758 1780 1758 1780 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.03	2.6	8.8	0.8	1	21	250	270	250	272	0.93
2	12	0.00028	0.024	15.2	0.2	1	23	282	304	282	304	0.98
3	12	6.8e-05	0.0058	17.1	7.3	1	23	310	332	310	332	0.98
4	12	1.8	1.5e+02	3.2	3.7	2	19	549	566	549	568	0.97
5	12	0.007	0.6	10.8	0.1	1	23	715	737	715	737	0.97
6	12	1e-05	0.00089	19.7	0.7	1	23	747	769	747	769	0.99
7	12	0.0007	0.06	13.9	2.0	1	23	775	798	775	798	0.97
8	12	0.0025	0.21	12.2	2.0	1	23	1074	1097	1074	1097	0.95
9	12	7.3e-05	0.0062	17.0	0.3	2	23	1481	1502	1480	1502	0.97
10	12	0.12	10	6.9	6.3	1	23	1508	1531	1508	1531	0.97
11	12	0.0071	0.61	10.7	0.5	3	23	1732	1752	1730	1752	0.96
12	12	0.0012	0.1	13.2	4.8	1	23	1758	1780	1758	1780	0.99

Sequence Information

Coding Sequence: ATGCTCGCgacacagcaacaacaacaaccgcagcccggcagtggcagcagcaccagcaataATAACGTAGCCGCCGCCACCCACACCAACACAGACGTAGTAGAGATGGAGCGGAAGCGGAGAGAATCCACAACGTCAGAATCTTCTCTCGAGCATCTCGACCTCGGGCGAACGCCAAAGAAGCTCAGCGGCAGCGCCGGTGCCGTGCAGTCGACATCGACGCCGCACGAGGTGGCTGCAACGTCGCGCAAGCGCAAGTTGcgccagctccagcagcagcaccatcaccaGCAAAGTCGGGATCTCCTCAGcgatgaggacgaggacgaggaggaagCACGTCCCCTCAATCGGCACAAACAGCGACGCGGCACCACCGCCGCCCAGGgatcctcctccgcctccattGTGGTGGACTACTCCGCCGGCGATGCCAGTTCGCTGCGCAAGAAGTTCCGTCTCAATCGTTCGGCGGCCAGTCTCTCGGAGTCGGGATTCGTGGATGCCAGCAGCACGGCCCACAGCGGCTTTCTGgtcaacaacagcagcagcgccagcacaAGCCTGGCAGTGCCTTCTGCCCCCACATCCGCCGCTAGTGGAGCAGCTGCCTCCGCCTCGAGTAGCAGCACCAGCactagcagcaacagcagcagcatcggcgGCGGTTCCGGTGGCTCCTCGCCACAGGGCCTGTGCCTCTCTAGCGGTGAATCTGGCATCGGTGCAGGCGACGAGCACATGAAATACCTGTGCCCCATCTGCGAGGTGGTCTCCGCCACGCCGCACGAGTTCACCAATCACATCCGATGTCACAACTATGCCAACGGGGACACGGAGAACTTCACCTGCCGCATCTGTTCCAAGGTGTTATCTTCGGCCTCATCCCTGGACAGGCACGTGCTGGTGCATACGGGCGAGCGGCCGTTCAACTGTCGGTACTGCCACCTGACCTTCACCACCAACGGCAATATGCACCGCCACATGCGCACTCATAAGCAGCACCAGACGGcgcagtcccagtcccagtcccagtcccataCGCAAGCCCaatcccagcagcagcgccgtcaacagcagcagcagcaaactcatcccgcccagcagcagcagcaacagcagcaacagcagacgCTGGTCAGCTCCATGCCAGTGCGGGCGGAGAGCTATGAAAGCGACGCTAGTTGTTCCACTGATGTGTCCAGCGGTAAtagtcgcagtcgcagcagtAGCTCCctccacaacaacaacaactcccACAAGGCtcataacaacaacaggaacAGCAAGCTTGAGCTGGAGGAGatgcaggagctggaggaggacaagcagcagctgcagcgtcGTTTGAAGACTACCATTAACAACAATGTCATCGGTGAAGAGAACCATGCGGAGGAGGATATGCATGGCGAGGAGGACGCCGACGATGCCGACGATGTGGCCATGCTCACAAGCACACCCGATGTCGCCACCCTGCTGGCAGGAGCCAGTGCCTCCGGTGCTGCATCCCGTTCGCCCTCGCCCTCGCCACCCGGCTCGCCCGGTCTGCTCCTGAGTTGCCCAGCCTGCGGAGCCTCCGATTTCGAGACGCTGCCTGCCCTGTGCGCCCATTTGGATGCCCGGCATTCGGATATACCGGCCAAGTGCCGGGACTGTGAGGTGATATTTGCCAGCCACCGCCAGCTGCAGGCGCACTGCTGCAGGGGACCTTCCTTGGGAGCGGGACTGCCGCCTATGCTTGGCGCCAGCAGTTCGCCTCTGCACGCCGACGAGGATGCCGaagacgaggaggaggcggatCACGAAGACGACGAGGAAATGGAGCACAAGCGTGACGACTTCTTCCACAAGCTATACCTCAAGGGAACATCAGCAGCGGGAGGAAACGGTGGCAGCGGCATCATTTCCCATCCACCGTCACCAATTAAGCACGAGCCGGCGGACAGCAAGGATCTGGCCGATATACAGAGCATCCTGAATATGACCAGTTCCAGCTGCACCAGCAGCTTCCTGCGCAACTTCGAGCAGTCTGTCAACACGCCCAGCTCCAGCCAGTACAGCTTGGATGGGCGCgatcaggaggaggaggcccagGATGCCTTCACCTCTGAGTTCCGCCGGATGAAGCTGCGCGGTGAGTTCCCCTGCAAGCTCTGCACCGCCGTTTTCCCGAATCTGCGCGCTCTCAAGGGCCACAACCGCGTCCACCTCGGAGCGGTTGGACCCGCGGGACCCTTCCGCTGCAACATGTGTCCTTACGCCGTCTGCGACAAGGCGGCCTTAGTACGGCACATGCGCACCCACAACGGTGACCGTCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGCCACCTGAGGAATCGGCACGGCAAGACCAGTCGCGAGGAGGTAAAGCGCGCCATTGTCTACCATCCCGCGGAGGACGCCGGCTGCGAGGATAGCAAGTCGCGGCTGGGTGAGGATCTGGCCGACATGAGTTTCCGCTCAATAAGTccgacgccgccgccaccgccgccgccagttgGTGAGAATAGCAGCTCCCAGCTAAAGCACATGCTCATGGGCGAGCAGCATCACTCCCAGACCCATCCCcatcataatcatcatcatccggtGGCGCCAGCTCAGCCGCCGCTAAAGATTCAGGTGAAGAGCCTGGACCAGCTGGTGGACAAGAAACCAGCGACAGTCCAACAGCCGGAGAAGAGCACCGCCTTGGACTTTAGCATGGATGTGTTGGATCTCAGTAAGAAGCCAACGGGTGCAGCGACGACCCCCACGCCCACACCCACGCCCTCGCTAACGCCGGCGCCCCTTGGTGCGGCTGCAGTGGCTGCTCCGGCTGCCGATCTGGCCGCCGCTTTGGAGCAACAGCAGTTGCTCctggcacagcagcagctcttcGGCGGTGCCAGCGACGCTGCCTCCCAGTACATGCAGCAGCTGTTCCGCAGCCTGGTGTTCCAGTCACAGACGCCGGGCTTCTCCTTCTTCCCGTTCATggcaccaccgccgccggagGTGAGCCAGGAGAAGGTGCCTCTGGTTAGTCCGCCATCGCGGATGAACCCACTGcccgtgggcgtgggcgttgGTGTGCCAGTGCCGCCCGGCGGACCGGTCAAAATGGTTATCAAAAACGGCGTCCTGATGCCGAAGCAGAAGCAGCGTCGCTACCGCACCGAACGTCCCTTCGCCTGCGAGCACTGCTCCGCCCGTTTCACGCTGCGCTCCAACATGGAGCGACACGTGAAGCAACAGCATCCGCAGTTCTATGCCCAGCGACAGCGCAGCGGTCACCATGTGATGAGGGGCAGGGGTGCCTCgaatgccgctgctgctgctgctgccgctgctgctgcagcggctgccaTTGGTCCGGCGGGGGGATCGTCCCATCATCATGCCCACGCCCACAGCCACAACCACAACCATGGCCATGGACATGGGCATGCTCCGATATCGGAGCAGGTGAAGTACGCCATTTTGGCGCAGCAGCTGAAGGCGCACAAGAACACCGATCTCCTGCAGCAGGCCTTGGCCCACGGCTCCAGCAGTGTGGCAGGCAATCCCCTTCTGCACTTCGGCTACCCACTGGGTCCCGCGCCCGGTGCTCCGCATGTGAGCGGTCAGGGAAACGGTCAGACGCCCATGGCCATGGACGACGATGAGCCCAAGCTGATCATCGATGAGGATGAGAACGAGCACGACCACGAAGTGGAGCCGGAAGATGTGGATGACTACGAGGATGAGgaagatgaggaggaggacgagccCGAGGATGAGCCGGAGGTGATTCTGGACGAGCCCTATGTCGCCGCGGGCGTCGAGAAGGAGGAGgcgccggaggaggagcagctacCCAAGCCCCTGGAGCAGCAAAGCTCAATGTCAACAAAGTCCAGCCCCAGTCCGAACGAGGCTGCCCAAAAGATGGCGGAGACCATCTTGGAGCAGGCCATCAAGGCTGGCAAGGAGCCATCAGCAACGACTCCGCCGTCCGTCGCGGCATCCTCTGTCCAGGAAGAGAATCCCCCAACTGCCGTAACACCACCGGCTGCCATGCAGGAGCCCAGCAGTAATCCCAGCAGCCTGAAGACCATGATAGCCCAGGCCGAGTCCGTCGGCAAGTCGCTGAAGGAGGTGGCTAGTTCGCCGTTCAAGGACGAATCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCCAAAATATGAGCTTCAACAGCTACTTCCGACCCAGCGATGTGGCCAATCACATGGAGCAAAGCGACGAGGAGGGCCTGGTGGCCTCTGGCAGTGCCAGCGagagcaacaacagcggcacGGAGGACGTCACCAGCTCCAGTTCGAGCAGCGAGCCAAAGAAGAAGTCCGCCTACAGCCTGGCCCCGAATCGCGTCTCCTGCCCATACTGCCAGCGCATGTTCCCGTGGAGCAGCTCCCTGCGCCGCCACATCCTCACGCACACCGGTCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGTGACCGCCATCTGCTGCGCAAGCACGGTAACGTCGAGTCCGCCATGTCGGTCTATGTGCCCACCGAGGATGTGAGCGAGCCCATTCCGGTGCCCAAGTCCGTGGAGGAGAtcgagctggaggagcagcgtCGCCGCCAGGAGGCGGAGCGGGAAAGGGAGCGCGAACTAGAGCGCGAGCGGGAGCTTGAGCGCGAGCGCGAGCTGGAGCGGGAGCGCGAACtggagaaggaaaaggagcaCGAACGTCAGCAGCTCATTCATAAGCTGGCCGCCCAgatggctgccgctgccgctgctgctgtctcgTGTGCCTCGCCGGGCAATGGGTCATCTGCCGGAGCCGGAGGCGATCTTTCGGCCGGCGGTGATCTGCCCTACAAGTGCCATCTGTGCGAGGGCTCCTTTGCCGAGCGCCTGCAATGCCTGGAGCACATCAAGCAGACGCATGCCCACGAGTTCGCCCTACTCCTCGCCAAGGGGGCGATCGAGAATGAGTCGTTGCACTCCGCCGCCGACTCATCGAATCCCCAGCAGCAGtcacaacaacatcagcactCGGACGACGAGGCCACCAATGGCCTGGGACGTGGCAAGTATCCGGATTATAGCAACCGAAAGGTGATCTGCGCCTTTTGTGTGCGCCGCTTCTGGTCCACCGAAGATCTTCGCCGCCACATGCGCACCCATTCCGGCGAACGCCCCTTCCAGTGTGACATCTGCCTCCGCAAGTTCACCCTCAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGGGCCCACAATGGGGATACGCCCGGCTCCGATTGCTCCGACGATGAGCAGGCGATGAGCAGTCCGCCTGGGACACCAGCCCCCTCTCCCATGCCCCTCCCCTccagcaccaacaacaacaatagctgtcagaataataataataataacaacaacaacaacaataataatagcaataataataacaataacaacaacaagctgGGCCTGAAGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGGGCGAGCCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCAACGCCCTCGGGAGCGGCGGCAGCTGGTTCGGATCTAATTGGGAACCTTCTGGGGATCAGCGATCAGGGCATACTCAACAAGTTGCTGTCCTCCGCCGATGAGGCGGCCAAGCTCCTGGGCGTGGAAAACAAGTGA
Protein Sequence: MLATQQQQQPQPGSGSSTSNNNVAAATHTNTDVVEMERKRRESTTSESSLEHLDLGRTPKKLSGSAGAVQSTSTPHEVAATSRKRKLRQLQQQHHHQQSRDLLSDEDEDEEEARPLNRHKQRRGTTAAQGSSSASIVVDYSAGDASSLRKKFRLNRSAASLSESGFVDASSTAHSGFLVNNSSSASTSLAVPSAPTSAASGAAASASSSSTSTSSNSSSIGGGSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAQSQSQSQSHTQAQSQQQRRQQQQQQTHPAQQQQQQQQQQTLVSSMPVRAESYESDASCSTDVSSGNSRSRSSSSLHNNNNSHKAHNNNRNSKLELEEMQELEEDKQQLQRRLKTTINNNVIGEENHAEEDMHGEEDADDADDVAMLTSTPDVATLLAGASASGAASRSPSPSPPGSPGLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGPSLGAGLPPMLGASSSPLHADEDAEDEEEADHEDDEEMEHKRDDFFHKLYLKGTSAAGGNGGSGIISHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADMSFRSISPTPPPPPPPVGENSSSQLKHMLMGEQHHSQTHPHHNHHHPVAPAQPPLKIQVKSLDQLVDKKPATVQQPEKSTALDFSMDVLDLSKKPTGAATTPTPTPTPSLTPAPLGAAAVAAPAADLAAALEQQQLLLAQQQLFGGASDAASQYMQQLFRSLVFQSQTPGFSFFPFMAPPPPEVSQEKVPLVSPPSRMNPLPVGVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAAAIGPAGGSSHHHAHAHSHNHNHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLGPAPGAPHVSGQGNGQTPMAMDDDEPKLIIDEDENEHDHEVEPEDVDDYEDEEDEEEDEPEDEPEVILDEPYVAAGVEKEEAPEEEQLPKPLEQQSSMSTKSSPSPNEAAQKMAETILEQAIKAGKEPSATTPPSVAASSVQEENPPTAVTPPAAMQEPSSNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERERELERERELERERELEKEKEHERQQLIHKLAAQMAAAAAAAVSCASPGNGSSAGAGGDLSAGGDLPYKCHLCEGSFAERLQCLEHIKQTHAHEFALLLAKGAIENESLHSAADSSNPQQQSQQHQHSDDEATNGLGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQAMSSPPGTPAPSPMPLPSSTNNNNSCQNNNNNNNNNNNNNSNNNNNNNNKLGLKLPKLHELLDKANEWRASRLGEHKENLGEATPSGAAAAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVENK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491706;
90% Identity: iTF_00491706;
80% Identity: -