Basic Information

Gene Symbol
RREB1
Assembly
GCA_008042675.1
Location
VNJU01009955.1:41328-47419[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.032 2.4 8.7 0.8 1 21 265 285 265 287 0.93
2 12 0.0003 0.022 15.1 0.2 1 23 297 319 297 319 0.98
3 12 7.3e-05 0.0053 17.0 7.3 1 23 325 347 325 347 0.98
4 12 1.9 1.4e+02 3.2 3.7 2 19 564 581 564 583 0.97
5 12 0.037 2.7 8.5 0.0 1 23 731 753 731 753 0.97
6 12 1.1e-05 0.00081 19.6 0.7 1 23 763 785 763 785 0.99
7 12 0.00075 0.055 13.9 2.0 1 23 791 814 791 814 0.97
8 12 0.0027 0.2 12.1 2.0 1 23 1108 1131 1108 1131 0.95
9 12 7.8e-05 0.0057 17.0 0.3 2 23 1537 1558 1536 1558 0.97
10 12 0.13 9.6 6.8 6.3 1 23 1564 1587 1564 1587 0.97
11 12 0.0076 0.56 10.7 0.5 3 23 1794 1814 1792 1814 0.96
12 12 0.0013 0.092 13.2 4.8 1 23 1820 1842 1820 1842 0.99

Sequence Information

Coding Sequence
ATGCTAGCGactcagcagcaacaacaacaacagcagcccggcagcagcaacaacaataacgtagccgccgctgccacacacacaatgatgaacagcagcagcaacaacaacaacacagaCTTGGTAGAGATGGAGCGCAAGCGAAGAGAGTCCACAACATCAGAATCCTCTCTCGAGCATCTCGACCTGGGACGAACGCCAAAGAAGCTCAGCGGCAGCGCCGGCGCTGCGCAGTCGACATCGACGCCGCACGAGGTGGCGACAGCGACGTCGCGCAAGCGCAAGCTGcgacagctgcagcagcagcaccaccaccagcagagTCGCTCGGATCTCCTTAgcgatgaggatgaggacgaggaggaggaggcacgTCCCCTCAATCGGCACAAGCAGCGACGCGGCGCCCAAGgatcctcctccgcctccgcctctgcCTCCATTGTGGTGGACTATTCCGCCGGCGATGCCAGTTCGCTGCGCAAAAAGTTCCGTCTCAATCGCTCGACGGCGGGCAGTCTCTCGGAATCGGGATTCGTGGATGCCAGCAGCACTGGCCACAGTGGCTACCTGGGcaacaatagcagcagcagcgccagcaccAGCCTGGTGCCAGCCGTGCCTTCAGTTGCCACAACCGTCGGAGCAGCAGGAGTAGCAGCAGCTCCCCCCTCGagtagcagcaacagcactagcagcagccacagcagttCCGGTGGCTCCTCACCGCAGGGCGGCCTGTGCCTGTCCAGCGGCGAGTCGGGCATTGGGGCTGGGGACGAGCACATGAAATACCTGTGCCCCATTTGCGAGGTGGTTTCCGCCACGCCGCACGAGTTCACCAATCACATACGATGCCACAACTATGCCAATGGGGATACGGAGAACTTTACCTGCCGCATCTGCTCCAAGGTGCTATCTTCTGCCTCATCCCTGGACAGGCACGTGCTGGTTCATACGGGCGAGCGGCCGTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAATGGCAATATGCATCGCCATATGCGCACTCACAAGCAGCACCAGACGGctcagtcccagtcccagtcgcagtcgcaaGCCCAAACCCAGCTGCAGCgtcgtcagcagcagcaacagcaccagcagcagcagcagcagcagcaacagcagcagaatcaTCCCGcccagcagccacagcagacGCTGGCCAGCTCCCTGCCAGTGCGGGCGGAGAGCTATGAAAGCGATGCCAGCTGCTCCACGGATGTGTCCAGTGCTAAtagtcgcagtcgcagcagtAGCTTTcttcacaacaacaacaacaactcacACAAggccaccaacaacaacaagcaagagctggaggagcagcaggagaagcacGAGCTGGAGCTAGAGGAGAGCAAGCATCTCCTACAGCGTCGCTTGAAGACAACCATCAACAACAATGTGATCGAAAATCATGCCGAGGAGGAACTGGaggatgctgatgctgatgttgCCATGTTGACAAGCACTCCGGATGTGGCCACACTGCTGGCCGGTGCCAGTGCCTCTGGGGCTGCCTCACGTTCGCCCTCGCCCTCGCCACCGGGCTCGCCCGGTTTGCTGCTCAGTTGCCCCGCCTGCGGTGCCTCCGATTTCGACAACCTGCCCGCCCTGTGCGCCCATCTGGATGCCCGGCATTCGGATATACCGGCCAAGTGCCGGGACTGTGAGGTGATCTTTGCCAGTCATCGCCAGCTGCAGGCCCATTGCTGTCGTGGAGGATCTGGATTGGGTGTGGGATTGCCGCCCATGCTGGGCGCCAGCAGTTCGCCGCTGCATGCcaacgaggacgaggaggaggaggagaacgagGAGGCGGATCATGAAGACGATGAGGAAATGGAGCAGAAGCGCGATGACTTCTTTCACAAGCTGTATCTCAAGGGTAATGCGGGTGGAGCGGGCGCAGCGGGCATTAGCTCACATCCTCCGTCGCCCATTAAGCACGAGCCGGCGGACAGCAAGGATCTGGCCGATATACAGAGCATCCTGAACATgaccagctccagctgcacCAGCAGCTTCCTGCGCAACTTTGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGATGGGCGCgatcaggaggaggaggcgcaGGATGCCTTCACCTCGGAATTTCGTCGGATGAAGCTGCGCGGCGAATTCCCCTGCAAGCTATGCGCCGCTGTCTTTCCGAATCTACGCGCCCTCAAGGGACACAATCGGGTGCATCTCGGTGCTGTGGGACCCGCGGGACCCTTTCGCTGCAACATGTGTCCCTACGCTGTCTGCGACAAGGCTGCGCTGGTGCGTCACATGCGCACCCACAACGGCGATCGGCCGTACGAGTGCGCCGTCTGCAATTATGCCTTCACCACCAAGGCCAACTGTGAGCGCCATTTGAGGAATCGTCATGGCAAGACCAGTCGCGAGGAGGTGAAGCGTGCCATTGTGTATCATCCCGCCGAGGATGCCGGCTGCGAGGACAGCAAGTCGCGTCTGGGCGAGGATCTGGCCGATATGAGTTTCCGTTCAATAAGTcccacgccgccgccgccgccgccaccagcAATGGgtgagagcagcagcagcaccagcagcagctcccagCTAAAGCACATGCTCCTaggcgagcagcagcagcatcatcattcGCATCACCATCACCCTCACCCTCATTCGGTGACCCCCGCTCAGCCGCCTTTAAAGATCCAAGTGAAGAGCCTGGACCAGTTGGTGGACAAGAAACCAGCGGCAGCTCAGCAGCCGGAGAAGAACTCTtcttccgccgccgccgcctcctccgccgccgccctgGACTTTAGCATGGATGTGTTGGATCTCAGCAAGAAGCCAACGGGAGCAGGcaccacgcccacgcccacacacacgccaTCGCTGACGCCGGCGCCACCGCTCGGCGCAGTGGCTCCCGCTGCCGATCTGGCCGCCGCTTTGGAGCAGCAACATTTGCTACTGGCACAGCAGCAACTCTTTGGCAGCGCCGGTGATGCTGCCTCCCAGTACATGCAGCAGCTGTTCCGCAGCCTGGTTTTCCAGTCTCAAACGCCGGGCTTCTCCTTCTTCCCCTTCATGgccccaccgccgccaccgccgccgccgcaggaGGTGAACTCGGAGAAGTCGCCACTGGTGAGTCCACCGTCGCGTATGAACCCACTGCCCGTGGGCGTGGGTGTGCCCGTGCCGCCCGGCGGACCCGTCAAAATGGTCATCAAGAATGGCGTCCTGATGccgaagcagaagcagcgTCGCTACCGCACCGAACGTCCCTTTGCCTGCGAGCACTGCTCCGCCCGGTTTACATTGCGCTCGAACATGGAGCGGCATgtgaagcagcagcatccgcagTTCTATGCCCAGCGACAGCGCAGCGGCCATCATGTGATGAGGGGCAGGGGAGCATCGaatgctgccgccgccgccgctgctgctgctgctgctgccgctgcagcggcTGGCATGGGTCCAGCGGCGGgatcctcctccgcctcccatcatcatcatcatcatcatcatcacggGCACAGTCACAACAACCATGGacatggccatgggcatgcACCCATTTCGGAGCAGGTGAAATATGCCATTTTGGCGCAACAGCTGAAGGCGCACAAGAACACGGATCTGCTGCAGCAGGCCTTGGCCCATGGCTCTAGCAGTGTGGCCGGGAATCCCCTCCTGCACTTTGGCTATCCGCTGGGTGCTGCAACCGGAGCTCCGGGGCATGTGAGCAGCCAGGGAAACGGTCAGGCGGGCGCCTTGGTCTTGGACGATGATGAGCCCAAGCTGGTCATCGATGAGGATGAAAATGATCACGATCATGAAGCGGAGCCGGAGGATGTTGATGATTACGAGGATGAGgaagatgaggaggaggatgagccCGAAGATGAGCCCGAGGTGATTCTAGACGAACCTCAGATAGTTGTGGAAAAAGAGGCGAAAGCCctggagaaggaggagcagcaggaagagGAGGTggatgatgaggaggaggagctggagctacCCAAGCCCCTGGAGCAGCTTAGCGCCATGTCCAAGTCCAGCCCGGGTCACAATGAGGCTGCCCAGAAGATGGCCGAGACCATTCTAGAGCAGGCCATCAAGGCTGGCATCAAGCAGCCTTCGGCAACGACTCCGGCTTCAGTGTCCTCCAACCAGGAGGAGCAGCCTCCGGCAGCTGTAACCCCTCCAGCTGCCATGCAGGAGCCCAGCAGTAATCCCAGCAGCTTGAAGGCCATGATTGCCCAGGCCGAGTCTGTGGGCAAGTCGCTCAAAGAGGTGGCCAGTTCACCGTTCAAGGACGAGTCCCAGGATTTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCCAGAACATGAGCTTCAACAGCTACTTCCGACCCAGCGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTGGTGGCCTCCGGCAGTGCCAGCGAgagcaacaacagcggcaCCGAGGATGtcaccagctccagctccagcagcgAGCCCAAGAAGAAGTCCGCCTACAGTCTGGCCCCGAATCGCGTCTCCTGTCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCCCTGCGCCGCCACATTCTCACCCATACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACCAAGAGCAACTGCGATCGCCATTTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCGGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCGGTGCCCAAGTCCGTCGAGGAGAtcgagctggaggagcagcgcCGCCGGCAGGAGGCGGAGCGCGAAAGGGAACGCGAGCTGGAGCGTGAACGTGAGCTGGAGCGAGAGCGTGAGCTGGAACGGGAGCGTgagctggagaaggagaaggagcggGAACGTCAGCAGCTTATCCACAAGCTGGCCGCTCAGATGAGTGccgcggcggcagctgctgctgcagccgctgctgcatGTGCCTCGCCGGGCAATGGATCGGGAGTTGGAGCTGGACCGGGAGGTGATCTTGCGGCCGGCGGTGATTTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTTGCCGAGCGTTTGCAATGCCTGGAGCATATCAAGCAGACGCATGCCCACGAGTTCGCTTTGCTCCTGGCCAAGGGTGCCATTGAGAATGAGTCGCTGCACTCCAATGACTCATCGAatacccagcagcagcagcagtcacaCAACCAGCACTCGGACGACGAGGCCACCAACGGCTTGGGTCGTGGCAAATATCCGGATTACAGCAACCGCAAGGTGATCTGCGCCTTCTGTGTCCGCCGCTTCTGGTCCACCGAGGATCTGCGGCGTCATATGCGCACCCATTCCGGCGAGCGGCCCTTCCAGTGCGACATTTGCCTGCGCAAGTTCACCCTGAAGCACAGCATGCTGCGTCACATGAAGAAGCACAGTGGCAGGGCCCATAATGGGGATACGCCCGGTTCCGATTGCTCGGACGATGAGCAGGCAATGAGCAGCAGTCCGCCGGGAACACCGGCTCCCTCGCCCATGCCGATGCcctccaacaacaacagctgccagaataataataataacaatacaaacaataataataataataataacaataataataataacaacaataagcTGGGATTGAAGCTACCCAAGCTGCACGAGCTGCTGGACAAGGCGAATGAGTGGCGAGCAAGTCGGCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCAACGCCATcgggagcagcggcagccggtTCGGATCTGATTGGTAACCTGCTGGGTATCAGCGATCAGGGCATACTCAACAAGCTGCTGTCCTCCGCCGATGAGGCAGCCAAGCTTCTGGGCGTGGACAACAAGTGA
Protein Sequence
MLATQQQQQQQQPGSSNNNNVAAAATHTMMNSSSNNNNTDLVEMERKRRESTTSESSLEHLDLGRTPKKLSGSAGAAQSTSTPHEVATATSRKRKLRQLQQQHHHQQSRSDLLSDEDEDEEEEARPLNRHKQRRGAQGSSSASASASIVVDYSAGDASSLRKKFRLNRSTAGSLSESGFVDASSTGHSGYLGNNSSSSASTSLVPAVPSVATTVGAAGVAAAPPSSSSNSTSSSHSSSGGSSPQGGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAQSQSQSQSQAQTQLQRRQQQQQHQQQQQQQQQQQNHPAQQPQQTLASSLPVRAESYESDASCSTDVSSANSRSRSSSFLHNNNNNSHKATNNNKQELEEQQEKHELELEESKHLLQRRLKTTINNNVIENHAEEELEDADADVAMLTSTPDVATLLAGASASGAASRSPSPSPPGSPGLLLSCPACGASDFDNLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGGSGLGVGLPPMLGASSSPLHANEDEEEEENEEADHEDDEEMEQKRDDFFHKLYLKGNAGGAGAAGISSHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCAAVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADMSFRSISPTPPPPPPPAMGESSSSTSSSSQLKHMLLGEQQQHHHSHHHHPHPHSVTPAQPPLKIQVKSLDQLVDKKPAAAQQPEKNSSSAAAASSAAALDFSMDVLDLSKKPTGAGTTPTPTHTPSLTPAPPLGAVAPAADLAAALEQQHLLLAQQQLFGSAGDAASQYMQQLFRSLVFQSQTPGFSFFPFMAPPPPPPPPQEVNSEKSPLVSPPSRMNPLPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAAAAAGMGPAAGSSSASHHHHHHHHHGHSHNNHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLHFGYPLGAATGAPGHVSSQGNGQAGALVLDDDEPKLVIDEDENDHDHEAEPEDVDDYEDEEDEEEDEPEDEPEVILDEPQIVVEKEAKALEKEEQQEEEVDDEEEELELPKPLEQLSAMSKSSPGHNEAAQKMAETILEQAIKAGIKQPSATTPASVSSNQEEQPPAAVTPPAAMQEPSSNPSSLKAMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERELERERELERERELERERELEKEKERERQQLIHKLAAQMSAAAAAAAAAAAACASPGNGSGVGAGPGGDLAAGGDLPYKCHLCEGSFAERLQCLEHIKQTHAHEFALLLAKGAIENESLHSNDSSNTQQQQQSHNQHSDDEATNGLGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDTPGSDCSDDEQAMSSSPPGTPAPSPMPMPSNNNSCQNNNNNNTNNNNNNNNNNNNNNNKLGLKLPKLHELLDKANEWRASRLGEHKENLGEATPSGAAAAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00491706;
90% Identity
-
80% Identity
-