Aash010749.1
Basic Information
- Insect
- Aphaenogaster ashmeadi
- Gene Symbol
- -
- Assembly
- GCA_003063805.1
- Location
- NJRQ01000635.1:5589-10302[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.093 11 7.2 3.1 1 23 396 418 396 418 0.97 2 19 0.016 1.8 9.6 0.5 2 23 455 476 454 476 0.96 3 19 0.022 2.5 9.2 3.2 1 23 539 561 539 561 0.98 4 19 0.013 1.5 9.9 1.2 1 23 564 586 564 586 0.98 5 19 3.9e-06 0.00044 21.0 0.7 2 23 635 657 635 657 0.97 6 19 0.0033 0.38 11.8 3.1 1 23 663 685 663 685 0.96 7 19 0.00063 0.071 14.0 0.7 1 20 691 710 691 715 0.94 8 19 8e-05 0.009 16.9 1.1 1 21 789 809 789 811 0.95 9 19 0.00021 0.024 15.6 4.8 1 23 866 888 866 888 0.97 10 19 0.00028 0.032 15.1 0.7 1 20 893 912 893 914 0.94 11 19 0.047 5.3 8.1 0.3 2 23 925 946 925 946 0.97 12 19 2.9e-05 0.0032 18.3 0.6 2 23 985 1006 984 1006 0.97 13 19 2.6e-05 0.0029 18.4 1.6 1 23 1011 1033 1011 1033 0.95 14 19 0.0011 0.13 13.3 1.7 1 20 1039 1058 1039 1061 0.93 15 19 4.6e-06 0.00052 20.8 0.4 1 23 1077 1099 1077 1099 0.95 16 19 3.7e-07 4.2e-05 24.2 0.6 1 23 1105 1127 1105 1127 0.99 17 19 4.1e-05 0.0046 17.8 0.2 1 23 1133 1155 1133 1155 0.97 18 19 0.024 2.7 9.1 6.9 1 23 1161 1183 1161 1183 0.96 19 19 0.0051 0.58 11.2 0.6 1 20 1189 1208 1189 1210 0.90
Sequence Information
- Coding Sequence
- ATGGACGCCGTGGAGATAAATACGTCGGGTCCGCCGCAAGGCGAGGACGCGATCGCGGCCGCGGTGAAGATATGCCGCGTCTGCCTGCTCGACAACCTGATGATGCGCGACCTCTTCGTGGAGAGCGAGGTCGCGTCCCTGTCTGCGAAGGCGATGAGCTTCGCCAACGTTAAGATGTTACCAGGCGACGGTCTACCAGCACAGGTGTGCTGCGTGTGCGCCGACAAACTGGAGTCGGCGTACGAGTTTAAATTACAAGTGGAGCAAGCCGACAGTGTTCTTCGAGAGAGGCTCGTTGGAGGAATAATAAAGGAGGAGTTGTTTCTTAATGAGGTTGAAATACACTTGGACACCGAGAGAAATGACGATATGGATGATATAAACGTCAGTACTGATTACGAATCTACCACCGAGGTGCTGCCAATGGAATCGGAAGCTGACAAGAACTTCCTGAAAGATCAGTTAATGATCTTGGAAGCTGAAAAATTGGCAGAAACAGAAGGAATGCAACAAGACCCGGAACAAGATAACTCGCAAGAAGTTAGTCAAGACATTGCGGAAGAGTTGCAGCAAGAATTAGCCAGCGCGGAAGACAATGATATGTCAGATGCTATCGAGGAATCTAGGGATGAAGAACCTTCTAGCGACGAGACTATCATTCGAAATTGCACAGAAGCAATTCCAACAGAGGAACATGATTATATTATGCAGCAACAGTGTATATTGCCTGCTGAGCAACTCTCATTACAGGAAGAAATGCAGGAGAGTGTACCAGAACTTGAACAAGACACAGTAGAATACCAAGAGACGCCATCTGAACAAAACCAAGAAATTCAGACTGATCAAAATCAAGAGATTCAAGCTCAGCAAATTTATGAGATTCAGGCTGAGCAAAACCAAGAGACTAAATTTCAGACTGAACTAAAGCAAGAAGATCAAGCCGAACAAGTTCAGGAGAATCAAGCTGAGCAAAATCAAAATGACAAGGAGGAAACGCCCAAAGCTGATACTAGTGAGCCAATAGTGGAACAAGAATCATCCCAGAATGAAACCAGAAGAAGTAAACGTAGATTAACTCGCCGGATATTCACCGAGCGGGATTCCGATGAGGAAAATTACTTCGAAAATCTGAATCTTAGTTCTCGATTGAAGAAAGCGCAGGCGGATAAGACGGAGAAGATCTTTTTCATGTGTTACTTGTGCGACAAGCAATTCCTTTCAAAGAACGTCCTGAAAGAGCATATGCATTCCCACGAAGAAGTGAGGAAGACGCTGTCCCTGAAGAAAACCCCGGAGAAACCGCAGAAGGTACAGACCAGTGTTTCCGTTGTGAAGACGCCGCCATCCGGAAAGAAAGCCAACAAGTGCCCTTATTGTGGTAAAGAGTATCTGTACATAATCTCGTTTACTAAACATATTAAGCAACATGAGCGAGAGGAAGCGAAGGAGGATCCGATGCCGCTCGAGATATCGTTCCATGAGGATGAGCATAGTTTAGACTTCGATAACGGCAACAAATTAGAAGGCAGAAAACGAAGAAGAGGAAGTACAGCCGATGACATCGCGAGCAATAGCGATCAggataaaagaagaaagcaTAATCCTGTTGAGGAGTTTACATGTGATAAATGTCCAGACAAATTCGATACAAAGCGAGGCTTGCATAAGCACTCTCTCACGCACGTTAGCTTCAAATGCAGCGTGTGCAACGACGAATACGACACTCTGGAACAATTGAGAAATCATCGAACGAAGCATGTGGTCGAGGGCGTGCTTACCGAGCAAGACTTGGAAGAGGACATAAAACAGATGATGACCAAGAGCGAAAATAACGATGAagacaacaaaaatattgaggATGAGGAGAACAACGGCGAATCCGCCGAAAACACGAAAGAACCCAAGTGTCCGACGTGTTCAATGACATTCTCACGCAAGAAAGCGCTGGCCAGACACATGGAGACAGCACACTCCAGCGCCCGCTCTTACGAATGCAAGATATGCTGTCAACAATTCACACGGAAGGATCTCCTGCGCAGGCATGCCGAGCAGCACGCACGAGTGAAGACCTACAAATGTACCCAATGCAACAAGACCTTCGGCAACGAGCTCACTCTGAGAAATCATCTGGTCGCTACAAATCACAAGACATTCATACATGGGCAGGAATACGATCCTAACAAGCGTATAAAGCGCGTGGCCGCGAGAGCGGCGCAGAAGATCATTGACAAGATCAAGACCGAGGATGGTCTCGAGGATTACGACGACGATAATGATGACAATACCGATTACGACGCCAAGTTGGACGGACATTATCGCCGTAAACGCGATGCTACACCAAAGAAGTACAATTATAAGAAGGAATTTGAGTGTGCGACCTGTAACAAGAAGTACAGCTCGAAGCAAGCATTGACGAAGCATATGCAGCCGCATGTGAAAGAGGAGAAAGCAGAGAAAGCGGCGGAGAAGGCGGCAGAGAAGCAGAAGAAAGCTGCTTTGGAGAAGAAGGAGCCGCAAAAGACGAGCAACACgggcgatgacgacgacgataacGACTCCGATTTTGAGAGTGGCCTCGACTGGCCGATGGACAGTCATGAATGCAGCACGTGCAAGAAGCGATACAGCACGAAGAAATCGCTGTTGCGTCACCAGCTATTGCACGAAGAGCCGAACTTTGAATGCGACATCTGCAACGTTAAATTCTATCGCAAAGATAAGCTGAAGGCGCACTATGACAAATGCTCGGAGAAAAATCCTGACCAAGTGAGAAAGTGCAACATCTGCGGCGATAGTTTCGAGAACAATGAGATCCTGCGCGAGCACAGGGCCAAGCACGTCGTCGAGGGTATCTTAACGGAGGAGGATCTAAGGGATATCGAGCCGAAATCCGAGGAGAAGAAGCCGGGCGAGAAGATCGGTCGAAAGAGGAGGACCGATATTGTGGGGCTCGAGTGTACCGAATGCAACAAACAGTACACCTCCAGGAAGGGCCTGCTGCGGCACATCCAGGTGCATGAGGGCAAGAAGTACCTATGCGACATATGCCCGAAGAAGTTCTACCGACGGGAACACTTGAAGATACACGTGGCCAAGCACAACATGATTAAACCATACAAGTGCACCCGCTGCACCAAGCGCTTTATCAAAGAAGAGCAGCTTAACAATCATCTGCCCAAGCACGATCGCACTTTTAAGAAGAGCAAGGAGACCGACAGCTCGAAGAGATTCCTCTGCGAGATCTGCAGCAAGAGCTTCACGCAATCGACGACGTTGATAGCGCATCTGCGCGCTCACAACGGTATCAAACCGTACGTGTGCGAGGTATGTTCCAGGCCGTTCACTACCAACGCCTACTTGAAGATGCATATGCGTACGCACACGCAGGAACGCCCGTACATCTGCCAATACTGTTCGCGAGCGTTCGCGCGTGCCGATACCTTGGCGAATCATCTGACATCGCATACTGGCGAAGCCAAGTATCATTGCAAGTGCTGTCCGAAGAACTTCCGACGATTAAAGTCGCTAAAGGAACACATGTTTATCCACACCGGTCAGCGACCTTACGAGTGTCCAACTTGCGACAGGAAGTTCAACAACAACGGCAGCCGCTATGCACACAGCAAGCGATGCAAACAGAATCTTTTGCAGAATCAGAACCGGGCGCAACAGATGATCCAACAGACGCAACAGCAGCATCAACAGCAGCACCAGCAGCAGCCGCAGCAAGTGCAGATACAGGTGCAGCAGTCGCAGCCGCATCCGGTCAGGCTGCATCAAACCACGATTGGCCAAGCGCAAATAGTCAAGGCGCAGAATATCAAGACGATCGCTATAGCGAGACAAGCTGAGCCTACCACGGTGGCAACGGCACAACAAGTCATGCAGCATCAGGAGATACTGATGCCTCTAATCCTGCCTCTTACCGTCACTCTCACCGACGTAGGCGAGGAGGTGATACTACCCGAGGGTACAAAGATATTCACCACCTCCTAA
- Protein Sequence
- MDAVEINTSGPPQGEDAIAAAVKICRVCLLDNLMMRDLFVESEVASLSAKAMSFANVKMLPGDGLPAQVCCVCADKLESAYEFKLQVEQADSVLRERLVGGIIKEELFLNEVEIHLDTERNDDMDDINVSTDYESTTEVLPMESEADKNFLKDQLMILEAEKLAETEGMQQDPEQDNSQEVSQDIAEELQQELASAEDNDMSDAIEESRDEEPSSDETIIRNCTEAIPTEEHDYIMQQQCILPAEQLSLQEEMQESVPELEQDTVEYQETPSEQNQEIQTDQNQEIQAQQIYEIQAEQNQETKFQTELKQEDQAEQVQENQAEQNQNDKEETPKADTSEPIVEQESSQNETRRSKRRLTRRIFTERDSDEENYFENLNLSSRLKKAQADKTEKIFFMCYLCDKQFLSKNVLKEHMHSHEEVRKTLSLKKTPEKPQKVQTSVSVVKTPPSGKKANKCPYCGKEYLYIISFTKHIKQHEREEAKEDPMPLEISFHEDEHSLDFDNGNKLEGRKRRRGSTADDIASNSDQDKRRKHNPVEEFTCDKCPDKFDTKRGLHKHSLTHVSFKCSVCNDEYDTLEQLRNHRTKHVVEGVLTEQDLEEDIKQMMTKSENNDEDNKNIEDEENNGESAENTKEPKCPTCSMTFSRKKALARHMETAHSSARSYECKICCQQFTRKDLLRRHAEQHARVKTYKCTQCNKTFGNELTLRNHLVATNHKTFIHGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDYDDDNDDNTDYDAKLDGHYRRKRDATPKKYNYKKEFECATCNKKYSSKQALTKHMQPHVKEEKAEKAAEKAAEKQKKAALEKKEPQKTSNTGDDDDDNDSDFESGLDWPMDSHECSTCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRAKHVVEGILTEEDLRDIEPKSEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLNNHLPKHDRTFKKSKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKCCPKNFRRLKSLKEHMFIHTGQRPYECPTCDRKFNNNGSRYAHSKRCKQNLLQNQNRAQQMIQQTQQQHQQQHQQQPQQVQIQVQQSQPHPVRLHQTTIGQAQIVKAQNIKTIAIARQAEPTTVATAQQVMQHQEILMPLILPLTVTLTDVGEEVILPEGTKIFTTS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00129923; iTF_00129173; iTF_00127671; iTF_00128413; iTF_00126903; iTF_01228516; iTF_01229183; iTF_01409382; iTF_01016008; iTF_01520456; iTF_00385772; iTF_01354771; iTF_01523542; iTF_01405943; iTF_01408464; iTF_01355609;
- 90% Identity
- iTF_00126903;
- 80% Identity
- -