Basic Information

Gene Symbol
-
Assembly
GCA_030770225.1
Location
JASTWK010000046.1:253354-258054[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.025 3.9 9.3 3.1 1 23 417 439 417 439 0.97
2 19 0.02 3.2 9.6 0.5 2 23 475 496 474 496 0.96
3 19 0.00054 0.086 14.5 1.1 1 23 563 585 563 585 0.96
4 19 0.0006 0.095 14.4 0.6 1 23 588 610 588 610 0.98
5 19 4.3e-05 0.0068 18.0 0.6 2 23 658 680 657 680 0.93
6 19 0.0043 0.68 11.7 3.1 1 23 686 708 686 708 0.96
7 19 0.00081 0.13 14.0 0.7 1 20 714 733 714 738 0.94
8 19 2.4e-05 0.0038 18.8 1.3 1 23 812 834 812 834 0.97
9 19 0.00025 0.04 15.6 5.0 1 23 894 916 894 916 0.97
10 19 0.00036 0.057 15.1 0.7 1 20 921 940 921 942 0.94
11 19 0.06 9.6 8.1 0.3 2 23 953 974 953 974 0.97
12 19 3.7e-05 0.0058 18.2 0.6 2 23 1013 1034 1012 1034 0.97
13 19 3.3e-05 0.0053 18.4 1.6 1 23 1039 1061 1039 1061 0.95
14 19 0.0014 0.23 13.2 1.7 1 20 1067 1086 1067 1089 0.93
15 19 5.9e-06 0.00094 20.7 0.4 1 23 1105 1127 1105 1127 0.95
16 19 4.8e-07 7.6e-05 24.2 0.6 1 23 1133 1155 1133 1155 0.99
17 19 5.2e-05 0.0083 17.7 0.2 1 23 1161 1183 1161 1183 0.97
18 19 0.031 4.9 9.0 6.9 1 23 1189 1211 1189 1211 0.96
19 19 0.0066 1 11.1 0.6 1 20 1217 1236 1217 1238 0.90

Sequence Information

Coding Sequence
ATGGACGCCGTGGAGATAAATACGTCGGGTCCGCCGCAGGGCGAGGACCCGATCGCGTCCGGCATGAAGATATGCCGCGTCTGCCTGCTCGGCAACCTGATGATGCGCGACCTCTTCCTGGAGAGCGAGGTCGCGTCCCTGTCGGCGAAGGCGATGAGCTTCGCCAACGTTAAGATGTTACCAGGCGACGGTCTACCGGCACAGGTGTGCTGCATGTGCGCCGCCAAGTTGGAGTCGGCGTACGAGTTCAAGTTACAAGTGGAGCAAGCCGACAATGTTCTTCGAGGAAAGCTCGTCGGTGGAATAATAAAGGAGGAGTTGTTTCTTAATGAAGTCGAAATACACTTGGATGCCGAGAGGAATGACAGTATGGAAGAGATTAGCGTCAGTGCTGATTATGAATCTACCACTACGGTATTGGCAGTGGAGTCAGCAGCTGACAAGAACTTTCTGAAAAATCAGTTAATGATTTTGGAAGCTGAGAAATTGTCAGAGACAGAGGAAATTCAACAGGATTCAGAACAAGATAACTCGCAAGAAAGCATTGTGGAAGAATTGCAGCAAGAATTGGCCGACGCGGAAGACAATGATACATCAGATGCTATCGATGAATCTAGGGCTGAAGAAGCTTCCAGCGACGAGAATATCATTCGAAGTTGCACAGATGCAATTCCAACAGAGGAACATGATTACATTATGCAGCAATGTAGTTTGCCTGCTGAACAACTCTCCTTGCAGGAAGAAATGCAGGAAAATGTACCAGAACTTGAACAAGACACAGTTGAATGCCATGAAGAAACATCGTCTGAACAAAACCAAGAGATTCAGGCTGAACAAAATCAAGAGATTCGAGCTGAGGAAGATCAAGAGATTCAAGCTGAGCAAATTCACGAAATTCAAGCTGAGCAAAACCAAGTGATTCCGGCTGAAATAAACCAAGAGATTCAGGCTGAAATAAATCGAGAGATTCAGACTGAATTAGATCAAGAAGCTCAAGCTGAGCAGGAGAATCAAGCTGAGCAAAATCAAAATGACACAGAGGTATTGTGCAAGGAGGAAACGCTCACAGCTAATACTAATGAGCCAGTGGAACAGGAATCATCCCAGAATGAAACTAGGAGAAGTAAACGTAGATTGGCTCGTCGGACATTTACCGAGCGGAATTCCGACGAGGagaattatttcgaaaatctgAATCTCAGTTCTCGATTGAAAAAAGCGCAGTCGGACAAGACGGAGAAGATCTTTTTCATGTGTTACTTGTGCGATAAGCAATTCCTTTCGAAGAGCGTCCTGAAAGAACATATGCATTCCCATGAAGAAGTGAGAAAAACACTATCTCTGAAGAAAACACCGGAGAAACCGCAGAAGGTGCAGGCCAGCGTTTCCGCGAAGACGCCGCCGTCCGGAAAGAAAGCCAACAAGTGCCCTTATTGTGGTAAAGAGTATCTGTACATAATCTCGTTTACCAAACACATTAAGCAACACGAGCGGGAGCGGGAGGAAGCGAAGGAGGATCCAATGCCACTCGAGATATCGTTCCATGAGGATGAGCACAGTCTGGACTTCGATAACGGCAACAGATCGGATGGCGAGTGCAAGAAGCGAAAGAGAGGAAATACAGCCGACGATGACGCGAGCGACAGCGATCAGGATAAGAGAAGGAAGCGCAGTCACGTTGAGGAGTTTGCGTGTGACAAATGTTCAGAAAAATTCGACACAAAGCGAGGCTTGCAGAAGCATTCGATCACGCATGTTAGCTTCGAGTGCAGCGTGTGTAACGAGGAGTACGACACTCTGGAACAACTGAGAAATCACCGAACGAGGCACGTGGTCGAAGGAGTGCTCACCGAACAGGATTTGGAAGAGGACATGAAGCAGCGGATGAAGAGCGAGAACAACGACGAAGACAACAAGAACATCGAGATTGAGGGGCACAACGGCGAACCCACCGAAAACACGAAGGAACTGAAGTGCCCGACGTGTTCGATGACGTTCTCGCGTAAGAAAGCGCTGTCCAGACACATTGAGGCGACGCACTCCAGCACCCGCTCTTACGAATGCAAGATATGCTGTCAACAATTCACACGGAAGGACCTCCTGCGCAGGCATGCCGAGCAGCACGCACGAGTGAAGACCTACAAGTGTACCCAGTGCAATAAGACCTTCGGCAACGAGCTCACGCTGAGAAATCACTTGGTTGCCACGAATCACAAGACATTCGTACACGGGCAGGAATACGATCCGAATAAGCGTATAAAGCGCGTGGCGGCGAGAGCGGCGCAGAAGATCATCGACAAGATCAAGACGGAGGACGGCCTCGAGGATTACGACGACGATAACGACGACAATACCGATTACGACGCCAAGTTGGACGGGCATTATCGCCGTAAGCGCGACGCTACACCAAAGAAGTACAGTTATAAGAAGGAGTTTGAGTGCGCGACCTGTAACAAGAGGTACAGCTCGAAGCAAGCGTTGACAAAGCACATGGAGCAGCATGTGAAGGAGGAGAAAGCGGAAAAGGCAGCGGAGAAGGCGGCGGAGAAGCTGAAGAAGGCGGCCGCTTTGGAGAGGAAGGAGGCGCAGAAGAAGGAGACGACTAGCAGCATAGGCgataacgatgacgacgataACGACTCCGACTTCGAGAGCGGCCTCGACTGGCCGATGGACAGTCACGAATGCACCACGTGCAAGAAACGATACAGCACGAAGAAGTCGCTGCTGCGCCACCAGCTGCTCCACGAGGAGCCCAACTTCGAGTGTGACATCTGCAACGTCAAGTTCTACCGCAAGGACAAGCTGAAGGCGCACTACGACAAGTGTTCCGAGAAGAATCCCGACCAGGTGAGGAAGTGCAATATCTGTGGCGACAGCTTCGAGAACAACGAGATCCTGCGCGAGCACAGAGCCAAGCACGTCACTGAAGGTATCTTAACGGAGGAGGATCTGAGGGACATCGAGCCGAAATCCGAAGAGAAGAAACCGGGCGAGAAGATCGGTCGGAAGAGGAGGACCGATATTGTGGGGCTCGAGTGTACCGAATGCAACAAACAGTACACCTCCAGAAAAGGTCTACTGCGGCACATTCAGGTGCACGAGGGCAAGAAGTATCTGTGCGACATATGCCCGAAGAAGTTCTACCGGCGGGAACATCTCAAGATCCACGTGGCCAAGCACAACATGATCAAGCCGTACAAATGCACCCGATGCACCAAGCGCTTCATCAAGGAGGAGCAGCTCAACAATCACCTGCCCAAGCACGATCGCACGTTCAAGAAGGCCAAGGAGACCGACAGCTCCAAGAGATTCCTCTGCGAGATCTGCAGCAAGAGCTTCACGCAATCGACGACGCTGATAGCGCATCTGCGCGCCCACAACGGTATCAAGCCGTACGTGTGCGAGGTATGCTCCAGGCCGTTCACCACCAACGCCTACTTGAAGATGCATatgcgcacgcacacgcaggAACGTCCGTACATCTGCCAGTACTGTTCGCGAGCGTTCGCGCGCGCCGACACATTGGCGAATCATCTGACGTCGCACACTGGCGAGGCCAAGTATCACTGCAAGTGCTGTCCGAAGAACTTCCGACGATTGAAATCGCTGAAGGAGCACATGTTTATTCATACGGGTCAGCGGCCTTACGAGTGTCCAACTTGCGACAGGAAGTTCAACAATAATGGCAGCCGCTATGCGCACAGCAAGCGGTGCAAGCAGAATCTTTTGCAGAATCAGAACCGGGCGCAGCAGATGATCCAGCAGACGACACAGCatcagcaacagcaacagcatcaacagcagcagcaacagcagcagccgcAGCCGCAGCAAGTGCAGATACAGGTGCAGCAGCAGCCGCATTCAGTCAGGTTGCATCAAACCATCGGCCAGGCGCAAGTAGTCAAGGCGCAGAACATCAAAACGATCGCTATAGCGAGACCGGCTGAGCCTACCACGGTAACCACGGCGCAACAAGTTATGCAGCATCAGGAGATACTAATGCCTCTAATCCTGCCGCTCACCGTCACTCTCACCGACGTAGGCGAGGAGGTGATACTACCCGAGGGTACGAAGATATACACCACCTCTTAA
Protein Sequence
MDAVEINTSGPPQGEDPIASGMKICRVCLLGNLMMRDLFLESEVASLSAKAMSFANVKMLPGDGLPAQVCCMCAAKLESAYEFKLQVEQADNVLRGKLVGGIIKEELFLNEVEIHLDAERNDSMEEISVSADYESTTTVLAVESAADKNFLKNQLMILEAEKLSETEEIQQDSEQDNSQESIVEELQQELADAEDNDTSDAIDESRAEEASSDENIIRSCTDAIPTEEHDYIMQQCSLPAEQLSLQEEMQENVPELEQDTVECHEETSSEQNQEIQAEQNQEIRAEEDQEIQAEQIHEIQAEQNQVIPAEINQEIQAEINREIQTELDQEAQAEQENQAEQNQNDTEVLCKEETLTANTNEPVEQESSQNETRRSKRRLARRTFTERNSDEENYFENLNLSSRLKKAQSDKTEKIFFMCYLCDKQFLSKSVLKEHMHSHEEVRKTLSLKKTPEKPQKVQASVSAKTPPSGKKANKCPYCGKEYLYIISFTKHIKQHEREREEAKEDPMPLEISFHEDEHSLDFDNGNRSDGECKKRKRGNTADDDASDSDQDKRRKRSHVEEFACDKCSEKFDTKRGLQKHSITHVSFECSVCNEEYDTLEQLRNHRTRHVVEGVLTEQDLEEDMKQRMKSENNDEDNKNIEIEGHNGEPTENTKELKCPTCSMTFSRKKALSRHIEATHSSTRSYECKICCQQFTRKDLLRRHAEQHARVKTYKCTQCNKTFGNELTLRNHLVATNHKTFVHGQEYDPNKRIKRVAARAAQKIIDKIKTEDGLEDYDDDNDDNTDYDAKLDGHYRRKRDATPKKYSYKKEFECATCNKRYSSKQALTKHMEQHVKEEKAEKAAEKAAEKLKKAAALERKEAQKKETTSSIGDNDDDDNDSDFESGLDWPMDSHECTTCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRAKHVTEGILTEEDLRDIEPKSEEKKPGEKIGRKRRTDIVGLECTECNKQYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLNNHLPKHDRTFKKAKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKCCPKNFRRLKSLKEHMFIHTGQRPYECPTCDRKFNNNGSRYAHSKRCKQNLLQNQNRAQQMIQQTTQHQQQQQHQQQQQQQQPQPQQVQIQVQQQPHSVRLHQTIGQAQVVKAQNIKTIAIARPAEPTTVTTAQQVMQHQEILMPLILPLTVTLTDVGEEVILPEGTKIYTTS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00126152;
90% Identity
iTF_01408464; iTF_01405943;
80% Identity
-