g168.t1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Amphipyra tragopoginis
Gene Symbol
Znf296
Assembly
GCA_905220435.1
Location
HG991991.1:22103214-22128279[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.0033 0.21 11.1 0.1 1 21 159 179 159 180 0.95
2 14 0.00049 0.032 13.7 2.1 2 20 193 211 192 215 0.95
3 14 0.21 14 5.4 0.1 2 23 255 276 254 276 0.91
4 14 5.4 3.5e+02 1.0 2.4 2 19 283 300 282 303 0.87
5 14 3.2 2.1e+02 1.7 0.2 3 23 356 377 355 377 0.88
6 14 0.0084 0.54 9.8 0.1 2 20 383 401 382 403 0.91
7 14 2.1e-05 0.0013 18.0 0.8 1 23 411 434 411 434 0.98
8 14 9.8e-06 0.00063 19.1 2.2 1 23 455 477 455 477 0.98
9 14 4.6e-06 0.0003 20.1 4.2 1 23 484 506 484 506 0.98
10 14 4.8e-08 3.1e-06 26.3 2.3 3 23 520 540 518 540 0.96
11 14 1.1e-05 0.00071 18.9 3.2 1 23 546 568 546 568 0.99
12 14 9.6e-07 6.2e-05 22.2 2.6 2 23 575 596 574 596 0.96
13 14 5.7e-08 3.6e-06 26.1 1.4 1 23 602 624 602 624 0.99
14 14 0.0014 0.087 12.3 0.1 1 23 630 652 630 652 0.97

Sequence Information

Coding Sequence
ATGGCTTCGATGCagaaaacagaaataaaaattgaagaatTGTGTCGAACATGTTTGTCTAAAGATAATGAATTACATTCGATATTTGATGTACTTGTAGGCACAACTATCACGTTAGACTATATAGTGACTTCAACAACTGGGCTCAAGATAAGCAAAAATGATGGTTTACCTTCAACAATTTGCTGTGAGTGTCAAGAAAAGGCAACAAAGGCATTTGATTTCAAGAATAAATCTGAAGAAGCTAACATGTCCCTGAGAGGAATATTAAAAAGAGAAAAGAAAGAATGGTCAACactaacaaaaactttaatccAACCCAATGCATCAGGTGTGAAGACTGAAGATTTTTCATCACATGAGAATGATGACTATGCGGACAGTGATTTCAATATTTCTCTGGCTAGCGGGCCAGATTTACATGAACTTGaagCTATAAAAAATGAGCGCGATAGTCACGAAAGGAAGTCATGCTATATATGCAAGAGTTGTTTGGTTGTTTTTGATACACAAGATAAATTACAAGATCACCAAAAGATATGCATAAAAGttgaaTGTGATGAAACCAACCGCACTTACTGTCCACTTTGTGGTACTTGCTACAACGGCGCTGAGAATTTAACGAAACATATGTGGGAATGTCATGCCGACCTAATGGGCCCGAAAAAGAGAGGCAGACCTAAGAAGATGTTAACAAGTACAATCCTCAACAAATTATCAGAAAATGGATTTTGCATAACATCAATGCCGGCAAAAAAGATTGAATGTGCATTTTGCAAGCAGCTTTTCGAAACCAAAGAAGAATTAGGATCACACGCCATAGGTCATAAAGATACGAAACTGCTACGTTGTTCGctatgcaaaaaaatatatctagaTAGAAACAATTTTGATCATCATAACTGTATTGAAGAGAAAACTGGTGTACTAACAAATAATGTGGAAAATGATTCATCTAATATAGAACCCATTGAAAAAAAGCCACAACATTTTCCGTCAGAAATTACACTGCGAGAAGTTTTACTCCCGAATATGGATATGgataatattaatttacttcAAATATGTAGTGCTTGTAACTGCGTATTACAATCTGAAGCCGATCTCATTAATCATCGCGATGCTGAGCACCCGGAACTTTCCCTTCGATGCAACCTCTGTACTAAGGTATTTGCTTCATTGCGGTCAGCGGCGCGCCATAGAAGCATTTGTAAGCAAattgaaagaaaatataaatgCAGCACATGTGGACTCAAATTCGCAtatgaaatatctttgaataagcATATTTTAAGATATCATGAGGGACAAAGTGTGTCAGTTAAATTTATTGATTCTAAAACTAAACGAGATGAGAGACAGTTTCAGTGTGATACATGCAACAGAAGTTTCTACAAgagAGACTTACTTGTTAAGCATACTAAAATACACATGCCAATCGAAAATTATTTCGAATGTGATGTTTGTCAAAAGAAGTTTCATAGAAGAGACAATTTACGGTCTCACAAACGAGTTCATGAGTTGCAGCGCGATAAGAGTTCATCTAGTAATTGCTTGTGCCTTTACTGTGGCCGCAGTTTCTCTAACTCATCGAACTTAATCGTGCACATGCGGCGCCATACCGGAGAGAAGCCCTACAAGTGTGACTTTTGTGGCAAAGGATTCCCAAGATCTTCTGATCTTCAGTGTCACAGACGATCTCACACCGGAGAAAAACCTTGCATCTGTCGTGTTTGTGGTAAAGgtttttcgCGCAGCAACAAGTTGTCCCGTCACATGCGCGTGCACACTGGTCAGAGGCCGTACAAATGCACGTACTGCGAGAAGGCGTTTTCTCAGAGCAACGATCTCAACCTGCACATACGTCGACACACTGGCGACCGGCCCTACATCTGCGAAGTGTGCGGCGATAGATTCATTCAGGGTACAGCATTACAGAATCATAGAAGAGCTCATGGTCACTTTCCTACTCCTGCTGAGGCACCTGCCGAAGTGCAAGCACTCACTTATACAGTCCAGAGTATAAGTCATAATAATAGTCACTAA
Protein Sequence
MASMQKTEIKIEELCRTCLSKDNELHSIFDVLVGTTITLDYIVTSTTGLKISKNDGLPSTICCECQEKATKAFDFKNKSEEANMSLRGILKREKKEWSTLTKTLIQPNASGVKTEDFSSHENDDYADSDFNISLASGPDLHELEAIKNERDSHERKSCYICKSCLVVFDTQDKLQDHQKICIKVECDETNRTYCPLCGTCYNGAENLTKHMWECHADLMGPKKRGRPKKMLTSTILNKLSENGFCITSMPAKKIECAFCKQLFETKEELGSHAIGHKDTKLLRCSLCKKIYLDRNNFDHHNCIEEKTGVLTNNVENDSSNIEPIEKKPQHFPSEITLREVLLPNMDMDNINLLQICSACNCVLQSEADLINHRDAEHPELSLRCNLCTKVFASLRSAARHRSICKQIERKYKCSTCGLKFAYEISLNKHILRYHEGQSVSVKFIDSKTKRDERQFQCDTCNRSFYKRDLLVKHTKIHMPIENYFECDVCQKKFHRRDNLRSHKRVHELQRDKSSSSNCLCLYCGRSFSNSSNLIVHMRRHTGEKPYKCDFCGKGFPRSSDLQCHRRSHTGEKPCICRVCGKGFSRSNKLSRHMRVHTGQRPYKCTYCEKAFSQSNDLNLHIRRHTGDRPYICEVCGDRFIQGTALQNHRRAHGHFPTPAEAPAEVQALTYTVQSISHNNSH*