Tlon006659.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Temnothorax longispinosus
Gene Symbol
KRBA2
Assembly
GCA_004794745.1
Location
QBLH01002732.1:567586-570524[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00011 0.0084 16.1 4.5 2 23 405 426 404 426 0.97
2 15 0.00018 0.014 15.4 2.6 2 23 433 455 432 455 0.95
3 15 2.7e-06 0.00021 21.1 1.5 2 23 543 564 542 564 0.97
4 15 1.2e-05 0.00093 19.1 3.6 1 23 570 592 570 593 0.96
5 15 8.1e-05 0.0063 16.5 0.4 1 23 598 620 598 620 0.97
6 15 0.00019 0.015 15.3 3.4 1 23 642 664 642 664 0.97
7 15 9.1e-07 7.1e-05 22.6 1.2 1 23 670 692 670 692 0.97
8 15 7.2e-06 0.00056 19.8 2.4 1 23 698 720 698 720 0.98
9 15 0.001 0.079 13.0 0.2 1 23 726 748 726 748 0.99
10 15 3.2e-05 0.0025 17.7 1.1 1 23 754 777 754 777 0.92
11 15 1.4e-05 0.0011 18.8 1.3 1 23 783 805 783 805 0.98
12 15 0.00031 0.025 14.6 4.7 1 23 811 833 811 833 0.98
13 15 4e-06 0.00031 20.6 0.4 1 23 839 862 839 862 0.97
14 15 4.4e-06 0.00034 20.5 0.8 1 23 868 890 868 890 0.96
15 15 2.4e-06 0.00018 21.3 4.8 1 23 896 918 896 918 0.99

Sequence Information

Coding Sequence
atgacaaaaataataatgaataaagaaaTGCCGTTGAGCGTGGAATGGATGCCACAAAACGCGTACATGCACAATTCTTTGGATCACTTGCTGCCGGGAGACAGAAATCAGGACTTCTTGATAATAAAGCAGGAAGcggaattttttcaaagtacCCTGAGCTCGCAATCTGCGCAAAACAAAGCGCATCTGCAAGTCTTATCTAAAGAGAAGGACAAGGAGATCAAGCAAGAGAACAGCTATTCAGATGTATTGGCGACAGTAAGTTTCAATCTTTTACTTTACTGTCTTTttaatgtatttgtatatgctaaaagtttaattaaaactatttcaTACATTTGTTTTCAGACCTGTCAAACGGACGCTTTAAATCGGTCGCCCAAAAGATTGACCGACGTTtcagagaaattatataataaaggtCGCATTGACGTAATAGAGATGACAATAGACccgacatttaattataaatatttcttcgtttATGAAGATCATTCGTCCAAGTTTGTCGTACTAAAGGCTCTCCGCAGCGATACGGCCAAAGAGGTTGCAGCGAATCTGTTAGACGTATTGGGGATCATAGGGGCACCACGAGTGCTGCAGAGCGGCAATGGGCGTAAGTTTGCCGAACAAGTTGTACGTGAACTACGTTCGCTGTGGAATGATTTGTTCATATTGCACGGGGACGCATCTAAGGGTGAAGTTAGCTACGGGGATTTTAAGACCTCGCTCGAATCCTGGATGAGAAAAAATCCAACTAGGACCTGGTGCGAAGGGCTGAACTTCGTACAGATCGTTCATAACTCGACGTATCGCTGTCAGAACGGCAAGGTCCCATACGACGTATTGTTCAGGCAAAACGTACGCGAGAATTTTCAAGGTATGGAAAAAGATGTGGAGGGTCTGAGGACGGAAGAGGAATGGCTCAAACATTTGTCGAATAAGAAGGACGGAGATGGGGCTGCAATGACGGGAGACACGCAGAATACATCAAAcagtattaatCAGTACGAAGAAAACGAAAATGTACGAGATACACGGAATCAAAACGCACTTTCGAAAGCCGACGATGTAAATATGTTCAGTTACGTGAACGTGAAGAATGAATCTCTGGcgaataacgcgcgcgcgatggatTCGATGTCTACGGATGAAACAGAAGACAAAGCGAAAAATGAATTGAAGGTCAACGAAGATACTCAATCCCTCAAATGCAAGTACTGTCAAAAGCAGTACATGAAGATAGGACATTTGAAGAACCACATGAGAACTCACAAAGCGAAGCAAGTTCTCCATTGTAAGCTGTGCAATAAAACATTTAGCGTTCCGAGATTGTACGCGAAGCATATGAAGCAATCACACGGACAGGATAAATTAGCTGATGAGGAAAGAGAGATACCGGTTAGCagaaatacgagaaacaaGGCCAATGCGTTAACGGCTACGCCTAACAAGGAAAGATCTGTGATTCGAACAACACACGAGACATCCGATCCCGGGAACAAAGATTGTGATTCGTCACTGGACACAAAAGAGTTTTCTGGCAAGGTCAGTAAGAGCTCAAACCAAACCGGCAGACGGAAGCTGCCTGCGGAGAGTCGCGTGTCGAAGGTACAATCTTTACAATGTACGTATTGCAAACAAAAGTTCAGCTTCCCGAGCGTGCTGGAGAGACACATGCGATCGCACACGAACGAACGGCCGTACGTGTGCGAGGTGTGTAACAAGAGCTTCAAACAATTAGGCCATCTTAGTCAGCACTCACTGACCCATCACGATTACCGTTCGTTCCAGTGCACGGTGTGCGACGTGAAGTTCGACTCGCTGGATTCGCTGAAGCAACACGCGTCCTCGCACAAAGGCgggacaacgacgacgacgacgacgacgacgtccaAGATACGCGACGTCTATCGCCTGTTCGAGTGCGACTGCTGCAAAAAAGTGTTCACGACGAAAAGCGTGCTGGAGCGGCACATATTCACGCACACGCAGGAACGCCAGTACGACTGCAAGGTATGCGGCAAGCGGTTCAAGCAGGCCGGTCACGTCAAGTCGCATATGCTGGTGCACACGGGCGAGCGTCGCTTCCAGTGCACAGTCTGCTCGAAACGCTTCAGCTTGTCGAACTCGCTGAAGAAACACATGTACGTGCACAACGGCGAGAAGCCGTATCAGTGCGACGTGTGCGGCGCGCGTTTCCTCGAGAAGCGCAACCTCAACGGCCACTTGCTGACGCACACCAACGAGCGTCCGTACTGCTGCAAGATCTGCGGTAAACGTTACACCTTGGCGGACACTCTGCGCCGTCACGTCAGCGCCGCGCATGAGGACGGTCGTACGTATCAGTGCGAGATCTGTGCCAAAATGTTCAAGCAATTGGCACATCTGTCGGTGCACAAGAAGGTGCACAACGACGAACGACCGTTCCAGTGTCACCTGTGCGAGAAGAACTTCAAGCACAAGAACGTGCTCAAGTCGCATCTGGCGATCCACGCGAACGTACGGCCGTTCGAGTGCGACGTGTGCAAGGCAACGTTCGTCAGGAAGACGAACCTGCAGACGCATATTTCGTCCGCGCACATGAACGAGCGTCCGTATTCCTGCACCATCTGCGGCAAGCGCTTCAAGCAGATCAGTCATCTGAACGGCCACGTGGTCGTGCACAGCAATCTGATGCCCTACAAGTGCGACTACTGCGAGCGCCGGTGCAATCGGCTTGACAATCTGAAGAAGCATATGCGCCTCCATATGAAGAACAAAGAGTGA
Protein Sequence
MTKIIMNKEMPLSVEWMPQNAYMHNSLDHLLPGDRNQDFLIIKQEAEFFQSTLSSQSAQNKAHLQVLSKEKDKEIKQENSYSDVLATVSFNLLLYCLFNVFVYAKSLIKTISYICFQTCQTDALNRSPKRLTDVSEKLYNKGRIDVIEMTIDPTFNYKYFFVYEDHSSKFVVLKALRSDTAKEVAANLLDVLGIIGAPRVLQSGNGRKFAEQVVRELRSLWNDLFILHGDASKGEVSYGDFKTSLESWMRKNPTRTWCEGLNFVQIVHNSTYRCQNGKVPYDVLFRQNVRENFQGMEKDVEGLRTEEEWLKHLSNKKDGDGAAMTGDTQNTSNSINQYEENENVRDTRNQNALSKADDVNMFSYVNVKNESLANNARAMDSMSTDETEDKAKNELKVNEDTQSLKCKYCQKQYMKIGHLKNHMRTHKAKQVLHCKLCNKTFSVPRLYAKHMKQSHGQDKLADEEREIPVSRNTRNKANALTATPNKERSVIRTTHETSDPGNKDCDSSLDTKEFSGKVSKSSNQTGRRKLPAESRVSKVQSLQCTYCKQKFSFPSVLERHMRSHTNERPYVCEVCNKSFKQLGHLSQHSLTHHDYRSFQCTVCDVKFDSLDSLKQHASSHKGGTTTTTTTTTSKIRDVYRLFECDCCKKVFTTKSVLERHIFTHTQERQYDCKVCGKRFKQAGHVKSHMLVHTGERRFQCTVCSKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLLTHTNERPYCCKICGKRYTLADTLRRHVSAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHISSAHMNERPYSCTICGKRFKQISHLNGHVVVHSNLMPYKCDYCERRCNRLDNLKKHMRLHMKNKE