Apic013570.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Aphaenogaster picea
Gene Symbol
KRBA2
Assembly
GCA_003063865.1
Location
NJRM01000136.1:82363-85306[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00014 0.016 16.1 4.5 2 23 374 395 373 395 0.97
2 15 0.00023 0.026 15.4 2.6 2 23 402 424 401 424 0.95
3 15 3.5e-06 0.00039 21.2 1.5 2 23 514 535 513 535 0.97
4 15 1.5e-05 0.0017 19.1 3.6 1 23 541 563 541 564 0.96
5 15 0.00014 0.016 16.1 1.0 1 23 569 591 569 591 0.97
6 15 3.6e-06 0.0004 21.1 1.3 1 23 609 631 609 631 0.98
7 15 1.2e-06 0.00013 22.7 1.2 1 23 637 659 637 659 0.97
8 15 9.3e-06 0.001 19.8 2.4 1 23 665 687 665 687 0.98
9 15 0.0013 0.15 13.1 0.2 1 23 693 715 693 715 0.99
10 15 4.1e-05 0.0046 17.8 1.1 1 23 721 744 721 744 0.92
11 15 1.8e-05 0.0021 18.9 1.3 1 23 750 772 750 772 0.98
12 15 0.0004 0.045 14.7 4.7 1 23 778 800 778 800 0.98
13 15 5.1e-06 0.00058 20.6 0.4 1 23 806 829 806 829 0.97
14 15 3.7e-06 0.00041 21.1 0.9 1 23 835 857 835 857 0.96
15 15 8.9e-07 0.0001 23.0 4.8 1 23 863 885 863 885 0.99

Sequence Information

Coding Sequence
ATGACAATAACAAGAATGAATAAAGAAATGCCGTTAAGTGTGGAATGGATACCACAAAACGCATATATGCACAATTCTTTGGATCATTTGCTGCCGGGAGATAGAAATCAGGACTTCTTAATCATAAAGCAAGAAGCAGAGTTCTTTCAAAGCAACCTAAATTCGCAATCTGTGCAAAACAAAGTCGTACATCTGCAAGTCTCAACTAAAGAGAAGGATAAGGAAACCAGGCAACAGAGCAGCTATTCGGATGCATTGACAACACCCTGTCAAACGGATTCTCTAAATCGATCGCCCAAAAGATTGACTGATGTTTcggagaaattatataataaaggaCGCATTGACGTAATAGAGATGACAGTGGATTCAACAtccaattataaatattttttcgtttatgAAGATCAGTCTTCCAAGTTTGTTGTACTAAAGGCTCTCCGTAGCAATACAGCCAAAGAGGTTGCGACGAATCTGTTAGATGTATTGGGGATCATAGGGGCACCGCGAGTCTTACAGAGCGGCAATGGACGTAAGTTTGCTGAACAAGTTGTACATGAACTACGTTTGCTGTGGAATGATTTGTTCATACTACATGGGGACACATCTAAGTGTGAAGTTAGCTACAGGGATTTTAAGAGTTCACTCGAATCCTGGATGAGAAAAAATCCAACCAAAACCTGGTGCGAAGGACTAAACTTCATACAGATCGTTCACAATTCGACATATCGCTGTCAAAATGGCAAAGTTCCGTATGACATATTGTTTAGACGAAACGTACGTGAGAATTTCCAAGGTATAGAAAAAGATATGGAAAATCTAAGGGCAGAGGAAGAATGGATCAAACATTTGTCAGTTAAGAAGGATAGAGATGTAGCTGCAACGATGGAAGACACGCAGAGTACATCAAAtagtattaatCAGTGCGAAGAAAACGGAAACGTACGAGATACACAGAGTCAAAACGTACTTTTGAAAGCAGACGATGTAAATATGTTTAGTTACGTTAACGTGAAGAATGAATCTCTGGCGAATAATGTGCGCGCAATAGATTTAGCGTCTACAGATGAAATAGACATGAAGAATGAATTGAAAATCAACGAAGATACTCAATCCCTTAAATGCAAGTACTGTCAAAAGCAATACATGAAAATAGGGCATTTGAAGAATCATATGAGAACTCACAAAACGAAACAGGTTCTCCATTGTAAGCTGTGCAATAAAACATTTAGCGTTCCAAGATTGTACGCGAAGCATATGAAGCAGTCACATGGACAAGATAAATTAGCCGATGATGAAAGAGAGGTACCGGTCAGTAGAAATACGAGAAAAAACGCCGATGCATTGACGGCTATATCTAACAAGGAAAGATCTGTGATTCAAACAAAACACGAGACATCTGATCAAGAAACAATGAATGAAGATTGTGATTCGTCGCTCGACACGAAAGAATCTTCTGGCAAGACTAGGAAGAGCTCCAACCAAACTGGTAGACGAAAGGTACCTGCAGAGAGCCGTCTGTCGAAGATACAATCCTTACAGTGTACGTATTGCAAGCAAAAATTCAGCTTTCCGAGCGTGCTGGAAAGACATATGCGATCGCACACAAATGAACGGCCATACGTGTGCGAGGTGTGTAACAAAAGCTTCAAACAACTGGGCCACCTCAGCCAGCACTCGCTGACCCATCATGACTACCGTTCGTTCCAGTGCACAGTATGTGGCGTAAAGTTCGATTCACTGGATTTGCTGAAGCAACATGCGCACTCGCATAAAGGtgatacgacgacgacgacctcCAAGATCCGCGATGTCTATCGTCTGTTCGAGTGCGACAGCTGCAAAAAGGTGTTCACGACAAAGAGCGTGCTGGAGCGGCATATATTCACGCACACGCAGGAACGTCAATATGACTGTAAAGTATGCGGCAAGCGATTCAAGCAAGCCGGTCACGTCAAGTCACACATGCTGGTGCATACGGGCGAACGTCGCTTTCAGTGCACTGTATGTTCAAAACGTTTCAGTCTGTCAAACTCGCTGAAGAAGCACATGTATGTGCACAATGGCGAGAAGCCATACCAGTGCGATGTGTGTGGTGCACGTTTCCTCGAGAAGCGCAATCTCAACGGCCACTTGCTGACGCACACCAACGAGCGTCCGTACTGCTGCAAGATCTGCGGCAAACGATACACCCTGGCGGACACTCTGCGTCGGCACGTCAGTGCCGCGCACGAGGACGGTCGTACGTATCAATGTGAGATCTGTGCCAAGATGTTCAAGCAATTGGCACATTTGTCAGTGCATAAAAAGGTGCACAACGACGAACGACCGTTCCAGTGTCACTTGTGTGAGAAGAACTTCAAGCACAAGAACGTGCTCAAGTCACACCTGGCGATCCACGCGAACGTACGGCCGTTCGAATGCGACGTGTGCAAGGCGACATTCGTCAGGAAGACAAATCTGCAGACGCACATCTCATCCGCGCACATGAACGAGCGTCCGTATACCTGTACCATCTGCGGCAAGCGCTTCAAGCAGATCAGCCATCTGAACGGCCACGTGGTCGTGCACAGCAATCTGATGCCCTACAAGTGCGATTACTGCGACCGTCGGTGCAATCGACTCGACAATCTGAAGAAGCATATGCGGCTCCATACGAAGAATAAGGAGTGA
Protein Sequence
MTITRMNKEMPLSVEWIPQNAYMHNSLDHLLPGDRNQDFLIIKQEAEFFQSNLNSQSVQNKVVHLQVSTKEKDKETRQQSSYSDALTTPCQTDSLNRSPKRLTDVSEKLYNKGRIDVIEMTVDSTSNYKYFFVYEDQSSKFVVLKALRSNTAKEVATNLLDVLGIIGAPRVLQSGNGRKFAEQVVHELRLLWNDLFILHGDTSKCEVSYRDFKSSLESWMRKNPTKTWCEGLNFIQIVHNSTYRCQNGKVPYDILFRRNVRENFQGIEKDMENLRAEEEWIKHLSVKKDRDVAATMEDTQSTSNSINQCEENGNVRDTQSQNVLLKADDVNMFSYVNVKNESLANNVRAIDLASTDEIDMKNELKINEDTQSLKCKYCQKQYMKIGHLKNHMRTHKTKQVLHCKLCNKTFSVPRLYAKHMKQSHGQDKLADDEREVPVSRNTRKNADALTAISNKERSVIQTKHETSDQETMNEDCDSSLDTKESSGKTRKSSNQTGRRKVPAESRLSKIQSLQCTYCKQKFSFPSVLERHMRSHTNERPYVCEVCNKSFKQLGHLSQHSLTHHDYRSFQCTVCGVKFDSLDLLKQHAHSHKGDTTTTTSKIRDVYRLFECDSCKKVFTTKSVLERHIFTHTQERQYDCKVCGKRFKQAGHVKSHMLVHTGERRFQCTVCSKRFSLSNSLKKHMYVHNGEKPYQCDVCGARFLEKRNLNGHLLTHTNERPYCCKICGKRYTLADTLRRHVSAAHEDGRTYQCEICAKMFKQLAHLSVHKKVHNDERPFQCHLCEKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHISSAHMNERPYTCTICGKRFKQISHLNGHVVVHSNLMPYKCDYCDRRCNRLDNLKKHMRLHTKNKE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01406725;
90% Identity
iTF_00129921;
80% Identity
iTF_00128411;