Dpse014882.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila pseudotakahashii
Gene Symbol
ftz-f1
Assembly
GCA_035046095.1
Location
JAWNOE010000226.1:581148-593894[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2 2.2e+04 -14.0 24.2 97 158 84 168 4 188 0.45
2 3 2.6e-19 2.9e-15 56.9 0.4 1 76 353 428 353 459 0.74
3 3 1.1e-70 1.3e-66 226.1 1.5 157 408 558 802 539 804 0.92

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAGCAACAGGCGACCGTACAGTTTATATCGTCGCTGAATATATCGCCGTTCAGCATgcagctggagcagcagcagcagccctcCAGTCCCGCCTTGGCCGCCggtggcaacaacaacaacaacaatgccagcggtagcagcaacaacaacagcggcggcggcaccagcagcaacaacaacaccagcagcagcaacaacaacaacaataataataacgaCAATGATGCACATGCTCTAACCAAATTCGAGCATGAGTACAATGCCTATACGTTGCAATTGGCTGGAGGCGGTGGTGCTAGTGGCGGTGGCAACCAGCAACACCACAGCAGCcaccaccagcaacagcagcagcagcagcagcaacaacagcagcaacatcagcagcagcaacaagaacactaccagcagcagcaacaacagaatATTGCCAACAATGCCAATCAATTCAACTCCTCGTCCTACTCGTATATATACAATTTCGATTCACAGTATATATTTCCGACAGGCTATCAGGACACCACCTCCTCGCATTCGCAGCAAagcggaggaggcggtgggGGCGGCGGTGGCAACCTGCTCAATGGCAGCTCCGGCGGCAGTTCCGCCGGCGGTGGCTACATGCTCCTCCCCCAGGCGGCCACTTCCAGTGGCAATAATAACAACCAGAATGCCGGCCACATGTCCTCCGGTTCCGTGGGcaacggcagcggcggcggcaacaaTGGCGGATCGGGCGGCGGATCCGGTCCGGGAAATCCCATGGGCGGCACGAGCGCAACGCCGGGACACGGCGGCGAGGTGATCGACTTCAAGCACCTGTTCGAGGAGCTATGCCCCGTGTGCGGCGACAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGCTCGTGCCACATCGACAAGACGCAGCGCAAGCGGTGTCCATACTGCCGCTTCCAGAAGTGCCTCGAGGTCGGCATGAAGCTAGAGGctgTTCGAGCGGATCGAATGCGGGGTGGACGAAACAAATTTGGACCCATGTACAAACGGGATCGGGCGCGGAAGCTGCAGGTGATGCGGCAGCGGCAGTTGGCGCTGCAAGCGCTGCGCAACTCGATGGGTCCGGACATAAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATAAAGCAGGAAATTCAAATACCTCAGgTATCCTCACTCACCCAATCTCCGGATTCGTCGCCCAGCCCCATAGCCATTGCGTTGGGACAGGTGAACGCGAGCACGGGCGGTGTGATAGCCACGCCCATGAACGCCGGCAACGGCGGCAGTGGGGGCGGAGGTCTCAACGGGCCCAGTTCCGTGGGCAATGGCAATAGtagcaacggcagcagcagcggcaacaacaacagcagcacgGGCAACGGAGCgtccggcggaggaggaggtggcaacAGTGcgggcggcggaggaggaggaaccaATTCCGTGGACGGCCTGCATCGCAACGGCGGCAATGGCAACAGCAGTTGCCACGAGGCTGGAATAGGATCTCTGCAAAACACGGCCGACTCGAAATTGTGcttTGATTCTGGCACACATCCATCGAGCACAGCTGACGCGCTAATCGAGCCATTAAGAGTCTCGCCGATGATTCGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAACTCTTTGCCCTGCTGCAGAAGCAAACCTACAACCAGGTGGAGGTGGATCTCTTCGAGCTGATGTGCAAAGTGCTCGACCAGAACTTATTCTCGCAAGTGGACTGGGCACGAAACACCGTCTTCTTCAAGGATCTGAAGGTCGACGACCAAATGAAGCTGCTGCAGCATTCCTGGTCGGACATGCTGGTTCTGGATCACCTGCATCATCGAATCCACAACGGCCTGCCCGATGAGACGCAACTGAACAATGGCCAGGTCTTCAATCTAATGAGCCTGGGATTGTTGGGCGTGCCACAGCTGGGCGACTACTTCAACGAGCTGCAGAATAAGCTGCAAGATCTGAAATTCGATATGGGCGATTATGTCTGTATGAAATTCCTAATCCTGTTGAATCCAAatGTACGGGGTATTGTCAACCGGAAGACCGTCTCCGAGGGACATGATAATGTGCAAGCAGCTCTGCTGGACTACACCCTCACCTGCTATCCGTCAGTCAATGACAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCTCGCGGCGAGGAGCACCTGTACACCAAGCACTGTGCCGGCAGTGCGCCCACCCAAACGCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGTGTAG
Protein Sequence
MLLEMDQQQATVQFISSLNISPFSMQLEQQQQPSSPALAAGGNNNNNNASGSSNNNSGGGTSSNNNTSSSNNNNNNNNDNDAHALTKFEHEYNAYTLQLAGGGGASGGGNQQHHSSHHQQQQQQQQQQQQQHQQQQQEHYQQQQQQNIANNANQFNSSSYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGGGGGGNLLNGSSGGSSAGGGYMLLPQAATSSGNNNNQNAGHMSSGSVGNGSGGGNNGGSGGGSGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGNGGSGGGGLNGPSSVGNGNSSNGSSSGNNNSSTGNGASGGGGGGNSAGGGGGGTNSVDGLHRNGGNGNSSCHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYTKHCAGSAPTQTLLMEMLHAKRKV