Dmon014214.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila monieri
Gene Symbol
ftz-f1
Assembly
GCA_035047585.1
Location
JAWNPJ010000106.1:3268176-3279796[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2 1.9e+04 -16.0 28.7 40 158 25 162 4 182 0.43
2 3 4.5e-19 4.3e-15 56.1 0.4 1 76 351 426 351 453 0.71
3 3 9.1e-72 8.8e-68 229.7 0.6 150 408 561 806 532 808 0.90

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAGCAACAGGCGACCGTACAGTTCATATCGTCGCTGAATATATCGCCATTCAGCATGCaactggagcagcagcagcagcagccctcCAGTCCCGCCCTAGCtggtggcagcaacaacaacactacaaccaccaccaccacaagcagcagcagcagcagcagcaacaacaccagcagcaccaacaacaataataataacaataacaacaatgaGGCACATGTTATAACAAAATTTGAACATGAATACAATACCTATACGTTGCAGTTGGCAGGCGGTGGTGGGAGTGGCAACTcgcaccaccaacaacaccaaaaccaacaccagcagcagcagcaacagcagcaacagcaacaccagcaacagcaacaacagctacAAGATCAATACCTACAACAACAGAATATTGCCAACAACGCCGCCAACCAATTCAACTCCTCCTCCTACTCCTACATCTACAATTTCGACTCACAGTACATATTCCCGACAGGCTACCAGGACACCACCTCCTCCCACTCCCAGCACAGCgggggcggtggcggtggcggtggcactGGGGGCGGCAACGGCCTCCTCAACGGCAGCTCCGGCGGCAGCTCtgtcggcggcggcggcggtggcgggtATGTCCTCCTCCCCCAGGCGGCCAGTTCCAGTGGCAATAATAACGGCATTGGCGGCCACATGTCCTCCGGCTCCATCGGCAACAACTCCGGCCTCAATAGCGTCGGCACCGGCACCGGGCCGGTCAACTCGCTGGGCGGCACCAGCGCCGCTCCGGGACATGTCGGCGATGTGATCGACTTCAAGCATCTGTTCGAGGAGCTGTGCCCCGTGTGCGGGGACAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGTGTGGCGGAGCGGTCGTGCCACATCGACAAGACGCAGCGCAAACGGTGTCCCTACTGCCGCTTCCAGAAGTGCCTCGAGGTCGGCATGAAGTTGGAGGctgTCCGAGCGGATCGCATGCGGGGTGGACGCAACAAGTTCGGACCCATGTACAAGCGGGATCGGGCGCGGAAGTTGCAGGTGATGCGGCAGCGGCAGTTGGCGCTGCAGGCCCTGCGCAACTCCATGGGCCCGGACATCAAGCCAACGCCGATCTCGTCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCGCCGGACTCGTCGCCCAGCCCCATTGCGATTGCGTTGGGTCAGGTGAATGCCAGTACGGGCGGAGTGATAGCCACGCCCTTGAATGCCGGCAACGGCGGGAGTGGCAACGGCGGGGGCCTAAACGGTCCCAGTTCCTTGGGAAATGGCAATagcagcaacggcagcagcagcagcggcggcaacaacaacaacggcggCAGCACGGGCAACAGTGCGGCCGGTGTCGggggaggcggcggcggcggcaataATGcgggcggcggtggtggcggcaaTTCCGGTTCCGCCGATGGCCTGCATcgcaacggcaacagcaattGCCACGAGGCTGGAATAGGATCTCTGCAGAATACGGCCGACTCGAAACCGTGCTTCGATTCCGGCACCCATCCATCGAGCACAGCCGACGCGCTTATCGAGCCATTAAGAGTCTCACCGATGATTCGTGAATTTGTGCAATCGATCGACGATCgggagtggcagacgcaactgTTCGCGCTGCTGCAGAAGCAAACCTACAACCAGGTGGAGGTGGATCTCTTCGAGCTGATGTGCAAAGTGCTCGACCAGAACCTGTTCTCGCAGGTCGACTGGGCACGCAACACGGTCTTCTTCAAGGACCTGAAGGTCGATGACCAAATGAAGCTGCTGCAGCACTCTTGGTCGGATATGCTGGTCCTGGATCACCTGCACCATCGCATCCACAACGGCCTGCCGGATGAGACGCAGCTGAACAATGGCCAGGTCTTCAATCTGCTGAGCCTGGGCCTGCTGGGAGTTCCCCAGCTGGCCGATTACTTCAACGAGCTGCAGAACAAGCTGCAGGATCTGAAGTTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTCTTGAATCCAGATGTGCGGGGTATTGTTAACCGGAAGACCGTCTCCGATGGGCATGATAATGTGCAAGCTGCTATGCTGGATTACACCCTCACCTGTTATCCGTCAGTTACTGAAAAATTCCGTAGGCTAGTTAATATCCTACCAGAAATCCATGCCATGGCCGCCCGCGGCGAGGAGCACCTGTACACCAAGCACGTCGCCGGCAGTGCACCCACCCAGACCCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGTGTAG
Protein Sequence
MLLEMDQQQATVQFISSLNISPFSMQLEQQQQQPSSPALAGGSNNNTTTTTTTSSSSSSSNNTSSTNNNNNNNNNNEAHVITKFEHEYNTYTLQLAGGGGSGNSHHQQHQNQHQQQQQQQQQQHQQQQQQLQDQYLQQQNIANNAANQFNSSSYSYIYNFDSQYIFPTGYQDTTSSHSQHSGGGGGGGGTGGGNGLLNGSSGGSSVGGGGGGGYVLLPQAASSSGNNNGIGGHMSSGSIGNNSGLNSVGTGTGPVNSLGGTSAAPGHVGDVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISSGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPLNAGNGGSGNGGGLNGPSSLGNGNSSNGSSSSGGNNNNGGSTGNSAAGVGGGGGGGNNAGGGGGGNSGSADGLHRNGNSNCHEAGIGSLQNTADSKPCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLADYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNRKTVSDGHDNVQAAMLDYTLTCYPSVTEKFRRLVNILPEIHAMAARGEEHLYTKHVAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00581562;
90% Identity
iTF_00477365;
80% Identity
iTF_00550300;