Datr002528.1
Basic Information
- Insect
- Drosophila atripex
- Gene Symbol
- ftz-f1
- Assembly
- GCA_035045925.1
- Location
- JAWNOP010000012.1:9619799-9630953[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.24 2.1e+03 -2.2 7.2 39 162 22 73 4 101 0.37 2 4 2 1.8e+04 -7.9 19.8 40 108 116 179 104 193 0.34 3 4 4.4e-19 4e-15 56.2 0.5 1 76 351 426 351 455 0.70 4 4 1.4e-71 1.2e-67 229.1 1.0 157 408 556 800 528 802 0.91
Sequence Information
- Coding Sequence
- ATGTTATTAGAAATGGATCAGCAACAGGCGACCGTACAGTTTATATCGTCGCTGAATCTATCGCCATTCAGCATgcagctggagcagcagcagcagcagccctcCAGTCCTGCCCTGGCtggtggcagcaacaacaacaacaacaacacaaccaccaccagcagtaacaacagcaacaacaacaacagcagcagcaacaccagcagcagcaacaacaacaataataacgaTAATGAGGCACATGTTAATGTTATAACAAAATTCGAACACGAATACAATGCCTATACGCTGCAGTTGAcgggcggtggtggtgggagTGGCAACTCgcaccaccagcaacaacaacaacaccagcagcagcaacagcagcagcaacaacaccagcaacaccagcaacaacaacagcaacaccagcaacagcagcaacaacaagatcactaccaacagcaacagattATTGCCAACAACGCCAACCAATTCAACTCCTCGTCCTACTCTTACATATACAATTTCGACTCACAGTACATATTCCCGACAGGCTACCAGGACACCACCTCCTCGCACTCGCAGCAGAGCGGGGGCGGTGGCGTTGGGGGCGGCAACCTCCTCAACGGCAGCTCCGGCGGCAGCTCTGTCGGCGGCGGCTATATCCTGCTCCCCCAGGCGGCCACCTCCAGTGGCAATAATAACGGCAATGTCGGCCACATGTCCGCGGGCTCCGTGGGCAACAACTCCGGCGTCAATAATGGAGGCGGCTCCGTGCCGGGCAACTCGATGGCCGGCACTAGCGCCGTTCCAGGACATGGCGATGTGATCGATTTTAAGCATCTGTTCGAGGAACTGTGTCCCGTGTGCGGGGACAAGGTGAGCGGCTACCACTATGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGGTCGTGCCACATCGACAAGACGCAGCGCAAAAGGTGTCCCTACTGCCGTTTCCAGAAGTGCCTCGAAGTCGGCATGAAGTTGGAAGcTGTCCGAGCGGATCGCATGCGGGGTGGACGCAACAAGTTCGGACCCATGTACAAGCGGGATCGGGCGCGGAAGCTGCAGGTGATGCGGCAGCGGCAGTTGGCGCTGCAGGCGCTACGGAACTCCATGGGCCCGGACATCAAGCCAACGCCGATCTCATCGGGCTACCAACAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCGCCGGACTCGTCGCCCAGCCCCATTGCGATTGCGTTGGGTCAGGTTCATGCCAGCACGGGCGGAGTGATAGCCACGCCCATGACCGCCGGCAACGGCGGTAGTGGCGGCGGCGGGGGCCTGAACGGTCCCAGTTCCTTGGGAAATGGCaatagcagcaacagcagcaccggcaacaacaacggcgGCAGCACGGGCAACAGTGCGGCCGGCGTCGGGGGAGGCGGCGGCAATAATGcgggcggcggtggtggcggcaaCTCGGGTTCCGTCGATGGCCTGCAtcgcaacggcaacagcaattgCCACGAGGCTGGAATAGGATCTCTGCAGAATACGGCCGACACGAAACCGTGCTTTGATTCCGGCACCCATCCATCGAGCACAGCCGACGCGCTTATCGAGCCATTAAGAGTCTCACCGATGATTCGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAACTGTTCGCCCTGCTGCAGAAGCAAACCTACAACCAGGTGGAGGTGGATCTCTTCGAGCTGATGTGCAAAGTGCTCGACCAGAACCTGTTCTCGCAGGTCGACTGGGCACGCAACACAGTCTTCTTCAAGGACCTGAAGGTCGATGACCAAATGAAGCTGCTTCAACACTCATGGTCGGATATGCTGGTCCTGGATCACCTGCACCATCGCATCCACAACGGCCTGCCGGATGAGACGCAGCTGAATAATGGCCAGGTCTTCAATCTGCTGAGCCTGGGACTGTTGGGAGTTCCCCAGCTGGCCGATTACTTCAACGAGCTGCAGAACAAGCTGCAAGATCTGAAGTTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTGTTGAATCCAGATGTGCGGGGTATTGTAAACCGGAAGACCGTCTCCGATGGGCATGATAATGTGCAAGCTGCTATGCTGGATTACACCCTCACGTGTTATCCGTCAGTTACtgaaaaattCCGTAGGCTAGTTAATATCCTACCAGAAATCCATGCCATGGCAGCCCGCGGCGAGGAGCACCTGTACACCAAGCACGTAGCGGGCAGTGCACCCACCCAGACCCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGTGTAG
- Protein Sequence
- MLLEMDQQQATVQFISSLNLSPFSMQLEQQQQQPSSPALAGGSNNNNNNTTTTSSNNSNNNNSSSNTSSSNNNNNNDNEAHVNVITKFEHEYNAYTLQLTGGGGGSGNSHHQQQQQHQQQQQQQQQHQQHQQQQQQHQQQQQQQDHYQQQQIIANNANQFNSSSYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGVGGGNLLNGSSGGSSVGGGYILLPQAATSSGNNNGNVGHMSAGSVGNNSGVNNGGGSVPGNSMAGTSAVPGHGDVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISSGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVHASTGGVIATPMTAGNGGSGGGGGLNGPSSLGNGNSSNSSTGNNNGGSTGNSAAGVGGGGGNNAGGGGGGNSGSVDGLHRNGNSNCHEAGIGSLQNTADTKPCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLADYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNRKTVSDGHDNVQAAMLDYTLTCYPSVTEKFRRLVNILPEIHAMAARGEEHLYTKHVAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581562;
- 90% Identity
- iTF_00477365;
- 80% Identity
- iTF_00481591;