Basic Information

Insect: Drosophila algonquin
Gene Symbol: ftz-f1
Assembly: GCA_035041765.1
Location: JAWNKY010000238.1:1480079-1491731[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.016 1.6e+02 1.6 9.9 40 153 25 184 5 195 0.59

2 3 8.2e-20 8.3e-16 58.6 0.8 1 79 350 427 350 448 0.76

3 3 2e-70 2e-66 225.3 1.7 157 409 561 806 545 807 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.016	1.6e+02	1.6	9.9	40	153	25	184	5	195	0.59
2	3	8.2e-20	8.3e-16	58.6	0.8	1	79	350	427	350	448	0.76
3	3	2e-70	2e-66	225.3	1.7	157	409	561	806	545	807	0.92

Sequence Information

Coding Sequence: ATGTTATTAGAAATGGATCAGCAACAGGCGACCGTACAGTTTATATCGTCGCTGAATATATCGCCGTTCAGCATGCagctcgagcagcagcagcagcagcagccctcgAGTCCGGCTCTGGCCGCCAATCAGCAGCCCCAAACGggctccaacaacaacaacaacaacaacagcagcagcagcggcggcggcaacaacaataacaacaacaacaacaacaacaacgataatGACGGAAATGGTCTTTCAAAATTCGAACATGAATACAACGCGTATACGCTTCAGCTAGCGGGTGGtgcaggaggggcaggaggcgGCACTGtcagtggcagccagcagcagcagcaccacagcacgcaccaccagcagcagtccgACCCGCAGGGCCActaccaacagcagcagcagcagcagcagcagcaacagaatatTGCCAACAACGCCAACAACCAATTCAACTCCTCGTCCTACTCGTATATATACAACTTCGATACAACACAGTATATATTCCCGACAGGCTACCAGGACACCACCTCCTCCCACTCGCAGCAGAGCGGCGgtgggggcggcggcggcggcggcggagctGGCGGCAACATCCTCAACGGCAGCTCGGGCAGCAGCTCTGGCTacatgctgctgccacaggcggccagctccagcggcaacaacaatgccgCTCACATGTCCTCGGCCAGCGGATCCGTTGGCAATGCCGGCGGCCCCaacggtggcggcggcggcggcggttcCGGTCCTGGCAATGCCATGGGCGGCACGAGCGCCACCCCAGGACACGGCGGCGAAGTGATCGACTTCAAGCATCTCTTCGAGGAACTGTGCCCCGTGTGCGGCGACAAGGTCAGTGGCTACCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGGACGGTCCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGGTCGTGCCACATCGACAAGACGCAGCGGAAACGGTGTCCCTACTGCCGCTTCCAGAAGTGCCTGGAGGTGGGCATGAAGCTGGAGGCTGTTCGAGCGGATCGGATGCGGGGTGGCAGGAACAAGTTCGGGCCCATGTACAAGCGGGATCGGGCGCGAAAGCTGCAGGTGATGCGTCAGCGGCAGATCGCCCTCCAGGCGCTGCGCAACTCGATGGGGCCGGACATCAAGCCGACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATCCAAATACCTCAGGTATCCTCACTCACCCAGTCGCCGGACTCGTCGCCcagtcccattgccattgctttGGGCCAGGTGAATGCCAGCGCGGGAGGAGTGATAGCCACGCCCATTAATGCCGGAAACGgaggcagtggcggcggcggcggcggtggcggcctGAACGGCCCCAGTTCCGTGGGCAATGGCAatagcagcaacggcagcagcagcaacaacaacaccggCAGCAGCACAGGCAACGGGGCAGGTGGCgccggcggaggcggcggtggcaacaatgcgggcggcggcggcggcaataACAGCTCCACCGATGGCCTGCATCGCAACGGCGGCGGCAATGGCAACTGCCACGAAGCTGGAATAGGATCTCTGCAGAACTCGGCCGACTCGAAACTGTGcttcGATTCCGGCACTCATCCATCGAGCACGGCCGATGCGCTTATCGAGCCACTAAGAGTCTCGCCGATGATACGAGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAGCTGTTCGCGCTGCTGCAGAAGCAGACCTACAACCAGGTGGAGGTGGATCTCTTTGAGCTGATGTGCAAGGTGCTCGATCAGAATCTGTTCTCGCAGGTGGACTGGGCAAGGAACACGGTCTTCTTTAAGGATCTGAAGGTCGATGATCAAATGAAGCTGCTGCAACACTCCTGGTCGGACATGCTGGTCCTCGACCATCTGCACCATCGCATCCACAACGGGCTGCCCGATGAGACGCAGCTGAACAACGGACAGGTCTTCAATCTGCTCAGCCTGGGCCTGTTGGGCGTGCCGCAGTTGTCCGACTACTTCAACGAGCTGCAGAATAAGCTGCAGGATCTGAAATTTGACATGGGCGACTATGTCTGCATGAAATTCCTAATACTTTTGAATCCAACTGTACGCGGTATTGTCAACAGGAAGACCGTGTCGGAGGGACATGATAATGTGCAGGCAGCCCTGCTGGACTACACCCTCACCTGTTATCCTTCAGTCCATGAAAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCACGCGGCGAGGACCACCTCTACACCAAGCACGTTGCCGGCAGTGCACCCACCCAGACGCTGCTCATGGAGATGCTGCACGCCAAACGGAAGGGATAG
Protein Sequence: MLLEMDQQQATVQFISSLNISPFSMQLEQQQQQQPSSPALAANQQPQTGSNNNNNNNSSSSGGGNNNNNNNNNNNDNDGNGLSKFEHEYNAYTLQLAGGAGGAGGGTVSGSQQQQHHSTHHQQQSDPQGHYQQQQQQQQQQQNIANNANNQFNSSSYSYIYNFDTTQYIFPTGYQDTTSSHSQQSGGGGGGGGGGAGGNILNGSSGSSSGYMLLPQAASSSGNNNAAHMSSASGSVGNAGGPNGGGGGGGSGPGNAMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQIALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASAGGVIATPINAGNGGSGGGGGGGGLNGPSSVGNGNSSNGSSSNNNTGSSTGNGAGGAGGGGGGNNAGGGGGNNSSTDGLHRNGGGNGNCHEAGIGSLQNSADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLSDYFNELQNKLQDLKFDMGDYVCMKFLILLNPTVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVHEKFSRLVNILPEIHAMAARGEDHLYTKHVAGSAPTQTLLMEMLHAKRKG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581562;
90% Identity: iTF_00471643;
80% Identity: iTF_00473834;