Basic Information

Insect: Drosophila mimetica
Gene Symbol: ftz-f1
Assembly: GCA_037075245.1
Location: JBAMCH010000004.1:5629033-5642537[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 2e+04 -10.7 21.1 38 158 21 159 4 177 0.47

2 3 2.6e-19 2.6e-15 56.9 0.4 1 76 344 419 344 450 0.74

3 3 1.1e-70 1.1e-66 226.1 1.5 157 408 549 793 529 795 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	2e+04	-10.7	21.1	38	158	21	159	4	177	0.47
2	3	2.6e-19	2.6e-15	56.9	0.4	1	76	344	419	344	450	0.74
3	3	1.1e-70	1.1e-66	226.1	1.5	157	408	549	793	529	795	0.92

Sequence Information

Coding Sequence: ATGTTATTAGAAATGGATCAGCAACAGGCGACCGTACAGTTTATATCGTCGCTGAATATATCGCCGTTCAGCAtgcagctggagcagcagcagcagccctcCAGTCCCGCCTTGGCCGCcggtggcaacaacaacaatgccagcggtagcaacaacaacagcggcagcagcagcaacaacaccagcagcagcaacaacaacaacaacaataacgacAATGATGCACATGCTCTAACCAAGTTCGAGCATGAGTACAATGCCTACACGTTGCAATTGgccggtggcggtggtgggagtggcagtggcaaccagcagcaccacaacagccaccaccagcagcagcagcaacaacagcagcagcagcaacatcagcagcagcagcaagaacactaccagcagcaacaacaacagaataTTGCCAACAATGCCAACCAATTCAACTCCTCGTCCTACTCGTATATATACAATTTCGATTCACAGTATATATTTCCGACAGGCTACCAGGACACCACCTCCTCGCACTCGCAGCAGagtggaggaggcggtggcggcggcgggggcAACCTGCTCAACGGCAGCTCCGGCGGCAGTTCCGCCGGCGGTGGCTACATGCTGCTCCCCCAGGCGGCCAGTTCCAGTGGCAATAATAACAGCCAGAACGCCGGCCACATGTCCTCCGGTTCCGTGGGCAACGGCAGCGGCGGGGGCAACAACGGCGGATCGGGCGGCGGATCCGGTCCGGGAAACCCCATGGGCGGCACGAGCGCCACGCCGGGACACGGCGGCGAGGTGATCGACTTCAAGCACCTGTTCGAGGAGCTCTGCCCCGTGTGCGGCGACAAGGTGAGCGGCTACCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACCGTGCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGCTCGTGCCACATCGATAAGACGCAGCGCAAGCGGTGTCCCTACTGCCGATTCCAGAAGTGCCTCGAGGTCGGCATGAAGCTAGAGGctgTTCGAGCGGATAGGATGCGGGGTGGACGCAACAAATTTGGACCCATGTACAAACGGGATCGGGCGCGGAAGCTGCAGGTGATGCGGCAGCGGCAGTTGGCGCTGCAAGCGCTGCGCAACTCGATGGGTCCGGACATAAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCTCCGGATTCGTCGCCCAGCCCCATAGCCATTGCGTTGGGACAGGTGAACGCGAGCACGGGCGGTGTGATAGCCACGCCCATGAACGCCGGCAACGGCGGCAGTGGGGGCGGAGGTCTCAACGGGCCCAGTTCCGTGGGCAATGGCAAtagcagcaacggcagcagcagcggcaacaacaacagcagcacgGGCAACGGAGCgtccggcggaggaggaggtggcaaCAATGCGGGCGGCGGGGGAGGAGGCACCAATTCCGCTGACGGCCTGCATCGCAACGGCGGCAATGGCAACAGCAGTTGCCACGAGGCTGGAATAGGATCTCTGCAAAACACGGCCGACTCGAAATTGTGcTTCGATTCTGGCACACATCCTTCGAGCACAGCTGACGCGCTAATCGAGCCATTAAGAGTCTCACCGATGATTCGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAACTCTTTGCCCTGCTGCAGAAGCAAACCTACAACCAAGTGGAGGTAGATCTCTTCGAGCTGATGTGCAAAGTGCTTGACCAGAACTTATTCTCGCAAGTGGACTGGGCACGAAACACCGTCTTCTTCAAGGATCTGAAGgTCGACGACCAAATGAAGCTGCTGCAGCATTCCTGGTCGGACATGCTGGTTCTAGATCACCTGCATCATCGAATCCACAACGGCCTGCCCGATGAGACGCAACTGAACAATGGCCAGGTCTTTAATCTGATGAGCCTGGGATTGTTGGGTGTGCCACAGCTGGGCGACTACTTCAACGAGCTGCAGAATAAGCTGCAAGATCTGAAATTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTGTTGAATCCAAATGTACGGGGTATTGTCAACCGGAAGACCGTCTCCGAGGGACATGATAATGTGCAAGCAGCTCTGCTGGACTACACGCTCACCTGCTATCCGTCAGTCAATGACAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCTCGCGGCGAGGAGCACCTGTACACCAAGCACTGTGCCGGCAGTGCGCCCACCCAAACGCTGCTCATGGAGATGCTGCACGCCAAGCGCAAGGTGTAG
Protein Sequence: MLLEMDQQQATVQFISSLNISPFSMQLEQQQQPSSPALAAGGNNNNASGSNNNSGSSSNNTSSSNNNNNNNDNDAHALTKFEHEYNAYTLQLAGGGGGSGSGNQQHHNSHHQQQQQQQQQQQHQQQQQEHYQQQQQQNIANNANQFNSSSYSYIYNFDSQYIFPTGYQDTTSSHSQQSGGGGGGGGGNLLNGSSGGSSAGGGYMLLPQAASSSGNNNSQNAGHMSSGSVGNGSGGGNNGGSGGGSGPGNPMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVIATPMNAGNGGSGGGGLNGPSSVGNGNSSNGSSSGNNNSSTGNGASGGGGGGNNAGGGGGGTNSADGLHRNGGNGNSSCHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYTKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00581562;
90% Identity: iTF_00536798;
80% Identity: iTF_00548120;