Dcon009397.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila conformis
Gene Symbol
-
Assembly
GCA_035041375.1
Location
JAWNLE010000862.1:7396215-7400394[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 2.9 1.9e+02 2.9 5.8 2 23 375 397 374 397 0.96
2 17 0.021 1.4 9.6 1.8 2 23 440 461 440 461 0.93
3 17 5.8 3.8e+02 1.9 2.9 2 17 472 487 471 498 0.75
4 17 0.029 1.9 9.2 0.4 3 23 531 551 529 551 0.95
5 17 0.001 0.065 13.8 0.3 1 23 559 582 559 582 0.98
6 17 3.8e-05 0.0025 18.2 0.2 2 23 587 608 586 608 0.97
7 17 7.2 4.7e+02 1.6 0.0 1 19 616 634 616 636 0.81
8 17 0.00034 0.022 15.2 0.3 1 22 656 677 656 680 0.90
9 17 1.3 82 4.0 3.7 3 21 687 705 687 706 0.93
10 17 0.015 0.96 10.1 0.6 1 23 725 750 725 750 0.96
11 17 0.013 0.87 10.2 1.4 2 23 766 788 765 788 0.93
12 17 0.0076 0.49 11.0 0.5 2 23 794 816 793 816 0.92
13 17 0.0027 0.18 12.4 0.2 2 23 820 842 819 842 0.96
14 17 0.00011 0.0071 16.8 4.4 1 23 848 870 848 870 0.98
15 17 0.0026 0.17 12.4 1.3 1 23 874 897 874 897 0.93
16 17 8.7e-05 0.0057 17.1 2.0 1 23 903 926 903 926 0.97
17 17 0.0044 0.28 11.7 0.2 1 23 930 958 930 958 0.89

Sequence Information

Coding Sequence
ATGtcggaaaatgaaaaaactgACGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGtacaattcaaaacaaaaatttcatgAGATATTCGACGAAGTCGGCATCGAAATAGAGCTCGCCAAACTGCTCGACAAGTATTTCGAGATAAAAGTTGAGCCCGTTGCcggaaaacaaaagcaactgctCTGCGAGGAGTGCGTTAATACGCTGATTCGTTTCTTCGACATCGACGAACTACAAAGGGAGCAAGATGCCGCAAATGCCGCCAATGCCGCAAATGCCGCAAATGCCGCCAATGCCGCGAATGTCGCAAATGTCGGAAAGAAAAAGCCCAGTAGTGATACAAAGTCTTCTGCAACCAAAAAGGATGAGAATCCCACCAAAAAGCAGACAGCTGCCATTAAAATTGGCCGAGGTTCACCAAACACCTCGGCGAATGCAGCCACGAAGCAAGAGAAGCCAACGCCGgatgctgctgcgactgttaCGTCTGATACTGCCACTGATGCCATTGCAAAAGGAGCGCCAGAAGCCGCTAACATACGGATCACCAGAGCCAGGAACGCTCCGCCAAAAAGATTACCCATAAATAGAATGAAAGCAGTCAACCGGAGTGGAACCCTTAATGCCAAAGCAGGCGTCAAACGGCGTAGATCCAGAGAAGCTGCTCAAGGATCAGGAGATCAGGAGCAAATTAGCGCACTCATACGTGACATTCTAGAGGACGTGGAGTCGCCAGCGGATGAAAAATTGGtggaagcagcagccacagtcCGTCAGCTAGAGAAACAATCAGCTGAAGAGCAACGGCAGCTGGAGGAGGCGGTGGAAAAGGAGCAAGCGGTGCTCGAGGACCAGGACAATAATGATGAGCTGGAGTTCCTGGTTGAGCGTGAAGATAGCTCTTCGGAATTGAGCGTGCGCCATTTCAAAGTGGAGCGAAAAATGAAACGCGCTCCTTCGCAGTCACAAAATGAGAGCCAAAGCGAGGATGAATCATTCAAAGTGGAGCCCTTCAATTTTGTGCTGATCAAGGAATCTGATAACATTGGCGATCTATACGAGTATTTGGGCAGCGTGGTGAAGACCTGTTTTGAGACATTGATGTTTGACTGGGACACTGTGTGCCGCCACTGCTCGCTGAAGTGCAGCAAATATCAAAGTTTATTCGGTCACATGCTGAGGCGCCACAAGGAGCCGGGTGTGATTTACAAGTGCCCGATTGCTGACTGCGCAACAGAGCTACAGGGAGCCAAATCTTTGGCCATGCACCTGGTTGTGCTGCATGCGCCGGTGGCCGATATACCCATTTATGGCAGTTGTCCCGAATGCAACATGACCTTCTCAAACATATTGCAGTACAACAAGCACTCATGCGCGCATGTCATCAAAAAGCGTCGCGGAATTCGCCTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAATTTTCacaatcaatttcatttggagcGTCACAGGCCACGCGCCTGTTTTGTGTGCAGCTACGCAGATACCAACATCGATGAGCTGTTCCATCATTTGCACTACGCTCATGAGCCAGAGGGCACGCTCTTCTGTGATCTCTGTGACCGCAATTTTCGTGATCCTGCCGTCTTTTCGGAGCACAACAAATCACACTCAAATGTCAGCAGTACCACCTACACCTGCACCGAATGCAGCGCCAATTTTGAGTCACGTGGTCGTCTCAATGGACACTTGCGCACCGCACATGGCAGCGTCATCAGCTGCGAAATGTGCGGCCGGGAGTTTGCCACGGAGGCCACCTACAACCTACACATGAAAACGCATTTGATCATTGAACGCGAGGTGCATGTGTGCAACAATTGCGGTCTGCTCAGCGAAAATAATGACAGGATGATGGCTCATGTGGCGGATGAGGACTTGGGTTGCTTTGGCATGGATGTGGCAGTGGAACTGATGCGTGATGCTTATGTTTGTGAGTACTGCTCCGCCTACTTTAAGCAGAAGAGTGATTTAAGCGCCCATCGCGATTCGGGGGTGCACAAGGATGGCCACTTCTGGTGTCATCCTTGCCGCAAGAAGTTTTCCGATATGAAGCTCTATCGCCACCACTTGCGCAACTATCAACAATTGCGCACAGATTTTTCGCATCGCCGGCTAGAAATTTGTCTCCACTATATGTGCGATTATGAGAATTGCAGTGAGGCCTATATTAATTGGAACTCGCTTTATACCCACAAGCGGCGTACACACGATGCTGCTGAGAAGCAGGAGCCCAAGATGAAAGATAACGAATGGATCTGTCAGTTCTGTCAGAAAGTGTGCCGCTCCAAAATGTCGCTCTCGGTTCACGTAGCgcgcagccacaacaacaATAATATGGTTTGCTCGCTGTGCAAAGCTTCGTATAAGGATGAGGAGGCGCTTAAAAAGCATCACGCCTATTGGCATGAGCGCATAGAGTGTCCGATGTGCTTGAAGGTGGTGAAGAATCGGCGCAACTTTGACACCCACATAAAGGTGGTGCACTCAAACAACAAGCGTTACACGTGCAGCGAATGCCAAAAAGGTTTCTATCACAAAAGCGAAATGGAGGCGCATCATCGGCTGCATTCGCAATCGTTTAAATGCGAACAGTGCAACTTCACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGCTGGGTCAGCACCAAAAGCGTTTTGCCTTCAAGTGTAAGTTCTGTGAAAAGCGCTTTGGACGCCGCCAGGGACTATCGAATCATATGCTACGTGTGCATGGTTCGAAGTACACATGTCGTGACTTCTTCGATGGCGGTTGTGGCAAATCATTTGGGTCAACGGCACGGCTCAACGTGCATGTGCGAAAGGCGCATAACAGCAGCCTCTTTCTGACCGACGACCCAGCCAAACCGGAGGATaacgaagaggaggaggaggaggaggtgccGGCTGTGGAGAATGCTGCACGCGAAGGTCCGTCCACATCGAAGAAACATTTAATTCGCATCAATGCGAACACTGAGATCGAATTCATTGGCGATGCAGCTGAGGCCAATGACGACAATGAGCATCTGACTGATTCGGAAGTCTTCGATGACTTGCAGGAGATCAAAGCACCAGCAAAGGCTCGGAAACGTTTGCGCAGTTTCGGCATATTaaaagcaccaacaacaaaaaaaagcgaataG
Protein Sequence
MSENEKTDENVPSCLHCRVYNSKQKFHEIFDEVGIEIELAKLLDKYFEIKVEPVAGKQKQLLCEECVNTLIRFFDIDELQREQDAANAANAANAANAANAANVANVGKKKPSSDTKSSATKKDENPTKKQTAAIKIGRGSPNTSANAATKQEKPTPDAAATVTSDTATDAIAKGAPEAANIRITRARNAPPKRLPINRMKAVNRSGTLNAKAGVKRRRSREAAQGSGDQEQISALIRDILEDVESPADEKLVEAAATVRQLEKQSAEEQRQLEEAVEKEQAVLEDQDNNDELEFLVEREDSSSELSVRHFKVERKMKRAPSQSQNESQSEDESFKVEPFNFVLIKESDNIGDLYEYLGSVVKTCFETLMFDWDTVCRHCSLKCSKYQSLFGHMLRRHKEPGVIYKCPIADCATELQGAKSLAMHLVVLHAPVADIPIYGSCPECNMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYAHEPEGTLFCDLCDRNFRDPAVFSEHNKSHSNVSSTTYTCTECSANFESRGRLNGHLRTAHGSVISCEMCGREFATEATYNLHMKTHLIIEREVHVCNNCGLLSENNDRMMAHVADEDLGCFGMDVAVELMRDAYVCEYCSAYFKQKSDLSAHRDSGVHKDGHFWCHPCRKKFSDMKLYRHHLRNYQQLRTDFSHRRLEICLHYMCDYENCSEAYINWNSLYTHKRRTHDAAEKQEPKMKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNMVCSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNFDTHIKVVHSNNKRYTCSECQKGFYHKSEMEAHHRLHSQSFKCEQCNFTTRNKKSLSVHVLGQHQKRFAFKCKFCEKRFGRRQGLSNHMLRVHGSKYTCRDFFDGGCGKSFGSTARLNVHVRKAHNSSLFLTDDPAKPEDNEEEEEEEVPAVENAAREGPSTSKKHLIRINANTEIEFIGDAAEANDDNEHLTDSEVFDDLQEIKAPAKARKRLRSFGILKAPTTKKSE