Basic Information

Insect: Drosophila melanosoma
Gene Symbol: -
Assembly: GCA_035042045.1
Location: JAWNLY010000205.1:1644019-1648010[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.41 28 5.4 5.6 2 23 336 358 335 358 0.96

2 18 4 2.7e+02 2.2 0.0 1 23 365 390 365 390 0.93

3 18 0.045 3.1 8.4 1.8 2 23 401 422 401 422 0.93

4 18 5.4 3.7e+02 1.8 3.0 2 17 433 448 432 459 0.75

5 18 0.029 2 9.0 0.6 3 23 492 512 490 512 0.95

6 18 0.0013 0.09 13.2 0.2 1 23 520 543 520 543 0.98

7 18 5.9e-05 0.004 17.4 0.1 2 23 548 569 547 569 0.97

8 18 8.6 5.9e+02 1.2 0.0 1 19 577 595 577 597 0.76

9 18 0.00011 0.0078 16.5 0.4 1 22 617 638 617 641 0.91

10 18 0.66 45 4.7 3.5 3 21 648 666 648 667 0.93

11 18 0.0077 0.52 10.8 0.7 1 23 686 711 686 711 0.96

12 18 0.011 0.77 10.3 1.4 2 23 727 749 726 749 0.93

13 18 0.012 0.79 10.2 0.5 3 23 756 777 755 777 0.93

14 18 0.0034 0.23 11.9 0.1 2 23 781 803 780 803 0.96

15 18 1.3e-05 0.00086 19.5 2.2 1 23 809 831 809 831 0.98

16 18 0.0022 0.15 12.5 1.3 1 23 835 858 835 858 0.93

17 18 0.0013 0.086 13.3 3.8 1 23 864 887 864 887 0.95

18 18 0.0054 0.37 11.3 0.1 1 23 891 919 891 919 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.41	28	5.4	5.6	2	23	336	358	335	358	0.96
2	18	4	2.7e+02	2.2	0.0	1	23	365	390	365	390	0.93
3	18	0.045	3.1	8.4	1.8	2	23	401	422	401	422	0.93
4	18	5.4	3.7e+02	1.8	3.0	2	17	433	448	432	459	0.75
5	18	0.029	2	9.0	0.6	3	23	492	512	490	512	0.95
6	18	0.0013	0.09	13.2	0.2	1	23	520	543	520	543	0.98
7	18	5.9e-05	0.004	17.4	0.1	2	23	548	569	547	569	0.97
8	18	8.6	5.9e+02	1.2	0.0	1	19	577	595	577	597	0.76
9	18	0.00011	0.0078	16.5	0.4	1	22	617	638	617	641	0.91
10	18	0.66	45	4.7	3.5	3	21	648	666	648	667	0.93
11	18	0.0077	0.52	10.8	0.7	1	23	686	711	686	711	0.96
12	18	0.011	0.77	10.3	1.4	2	23	727	749	726	749	0.93
13	18	0.012	0.79	10.2	0.5	3	23	756	777	755	777	0.93
14	18	0.0034	0.23	11.9	0.1	2	23	781	803	780	803	0.96
15	18	1.3e-05	0.00086	19.5	2.2	1	23	809	831	809	831	0.98
16	18	0.0022	0.15	12.5	1.3	1	23	835	858	835	858	0.93
17	18	0.0013	0.086	13.3	3.8	1	23	864	887	864	887	0.95
18	18	0.0054	0.37	11.3	0.1	1	23	891	919	891	919	0.87

Sequence Information

Coding Sequence: ATGTCGGAAAATAAGAAATCTGACGAAAATGTGCCTAGCTGCCTGCATTGCAGAGTGtacaattcaaatcaaaaatatcaTGAGATATTCGACGAAATCGGCATTGAAATTGAGCTCGCCAAACTGCTCGACAAGTATTTCGAGATAAAAGTTGAGCCCGATGCCCAAAAGCAGAAACAGCTGCTCTGCGAGGAGTGCGTTAATACGCTGATTCGTTTCTTTGACATTGACGAACTTCGAAGGGAACAAGatgctgcaaatgctgcaaagAAAAATCCCTCTAATGATACAAAGTCTTTTACAAAATCCGCCAAAGACGATGAAATTCCCGCCAAAAAGCAGACAGCTGCCGTCAAAAATGGCCATGGTTCCcgaataaaacaagaaaagccAACGGTAGCTGCAAGTGTTACAACTGCTAcgactactactactactgcaGCACATGATGTTATTGCAACAGGAGCGCCAGAAGCCGTCGGCAAGCGAAGTGAAACATCTAATGGCAATGCAGGCGTCAAACGGCGTCGGTCCAGAGAATCTGCTCAAGGATCAGGAGATCAGGAGCAGATTAGCGCACTCATTCGTGACATTCTAGAGGATGAGGAGTCCCCAGCCGATGAAAAGTTGgtagaagcagcagccacagtcTGTCAACTGGAGAAAGAATCAGCTGtagagcaactgcagctggatGAGGCGGTGGAGGTAGAGGAACAAGCGGTGTTCGACGACCaggataataataatgagctGGAGTTTTTGGTTGAGCGTGAAGATAGCTCCTCGGAATTGAGCGTGCGCCACTTCAAACTGGAGCGAGTTAAAGTTAAACGCACCATATCGCAGTCACAAAATGAGAGCCAAAGCGAAGACGAGGCATTCAAAGTGGAGCCCTTTAATTTTGTGCTAATCAAGGAATCTGATAACATTGGCGATCTATACGAGTATTTGGGAACCGTGGTGAAGACCTGTTTTGAGACTTTAACCTTTGACTGGGACACAGTGTGCCGCCACTGCTCGTTGAAGTGCAGCAAATATGAAAGTTTATTCGATCACATGCTGAAGCGTCACAAGGAGCCAGGCGAGATTTACAAGTGCCCGATTACTGAGTGTACCATAGAACTGCAGGGAGCCAAGGCCTTGGCCATGCACCTAATTGTGCTGCATGCGCCAGTAGCCGATATTCCCATTTATGGCAGCTGTCCCGAATGCAGCATGACCTTCTCAAATATATTGCAGTACAACAAACACTCCTGCGCGCATGTCATCAAAAAGCGTCGCGGCATACGCTTGTATTGTGAGATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGCTTTAATTTTCACAATCAATTTCATTTGGAGCGTCACAGGCCGCGCGCCTGTTTTGTGTGCAGCTACGCGGATACCAACATAGATGAGCTTTTCCATCATTTGCACTACTCTCACGAGCCAGAGGGCACGCTCTTCTGTGATCTCTGTGATCGCAATTTTCGTGATCCTACAGTCTTTTTGGAGCACAACAAATCACACTCAAATGTCAGCAGCACCACCTACAGCTGCACCGAATGCAGCGCCAATTTTGAGTCACGTGGTCGTCTCAATGGACATCTGCGCACCGCACATGGCAGCGTCATTAGCTGCGAAATGTGTGGCCGCGAGTTTGGCACGGAGGCCACCTACAACGTGCACATGAAGACACATCTGATTATTGAGCGCGAGGTTCATGTGTGCAACAATTGCGGACTGCTTAGCGAAAATAATGATAGGATGCTGGCTCATGTGGCCGATGAGGATTCGGCTTGCTTTGGCATGGATGTGGTAGCGGAACTGATGCGTGATGCATACGTTTGTGAATATTGCTCGGCCTACTTTAAGCAGAAAAGCGATTTAAGCGCCCATCGCAATTCGGGGGTCCATAAGGATGGCCACTTTTGGTGTCATCCTTGCTCCAAGAAATTTACCGATATGAAGCTCTACCGCCACCACCTGCGCAACTATCAACAATTGCGCACAGATTTTTCGCATCGCCGTCTGGAAATTTGTCTCTACTATATGTGCGATAATGAGAAATGCACTGAGGCGTATATTAATTGGAATTcgctatacacacacaaacggcGCACACACGACGCCGCCGAGAAGCAAGAGCCCAAGTTAAAAGATAACGAATGGATCTGTCAGTTCTGTCAGAAAGTATGCCGCTCCAAAATGTCGCTATCGGTTCACGTGGCGCGCAGTCACAACAACAATAATGTGGCTTGCTCGCTGTGCAAAGCATCGTATAAGGATGAGGAGGCGCTAAAAAAGCATCACGCCTATTGGCATGAGCGCATAGAGTGTCCGATGTGCTTGAAGGTGGTGAAAAATCGACGCAACTATGACACCCACATAAAGGTGGTGCACTCAAACAAGAAGCGTTATTCGTGCAGTGAATGCCAAAAAGGTTTCTATCACAAGAGCGAAATGGAGGCGCATCAGCGGCTGCATTCGCAATCGTTTAAATGCGAACAGTGCAACTTTACCACGAGGAACAAGAAATCGCTGTCGGTTCATGTGCTGGGTCAGCATTACAAGCGTTTTGCCTTCAAGTGTAAGTTCTGTGACAAGCGCTTTGGACGCCGCCAGGGACTATCCAATCATACTCTACATGTGCATGGCTCAAAATTTACATGTCGTGACTTCTTTGAAGGCGGTTGTGGCAAAGCATTTGCATCGATGGCACGGCTCAACGTGCATGTCCGAAAGGTGCATTACGGCACCCAGTTTCTGGCCGATGACCCAACCAAATTAGACGAAAAGGAGCaggcggaggaggaggcggaggaggaggcggaggaggaggcggaggaggaggaggagccgGAGGCAAGCGATGGTCCGTCCACATCGAAGAAACGTTTGATTCGCATTAGTGCAAACACTGAGATTGAATTCATTAGCAATGcagccgatgccgatgccgatgacGACAATGAAAGTCTGACTGATTCCGAAATCTTCGAAGAGTTTAAGGAGgtgaaagcagcagcaaagcagccaccaaaaaagaaaccaaaaccaaTGACAACGAGAGCCTGA
Protein Sequence: MSENKKSDENVPSCLHCRVYNSNQKYHEIFDEIGIEIELAKLLDKYFEIKVEPDAQKQKQLLCEECVNTLIRFFDIDELRREQDAANAAKKNPSNDTKSFTKSAKDDEIPAKKQTAAVKNGHGSRIKQEKPTVAASVTTATTTTTTAAHDVIATGAPEAVGKRSETSNGNAGVKRRRSRESAQGSGDQEQISALIRDILEDEESPADEKLVEAAATVCQLEKESAVEQLQLDEAVEVEEQAVFDDQDNNNELEFLVEREDSSSELSVRHFKLERVKVKRTISQSQNESQSEDEAFKVEPFNFVLIKESDNIGDLYEYLGTVVKTCFETLTFDWDTVCRHCSLKCSKYESLFDHMLKRHKEPGEIYKCPITECTIELQGAKALAMHLIVLHAPVADIPIYGSCPECSMTFSNILQYNKHSCAHVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCSYADTNIDELFHHLHYSHEPEGTLFCDLCDRNFRDPTVFLEHNKSHSNVSSTTYSCTECSANFESRGRLNGHLRTAHGSVISCEMCGREFGTEATYNVHMKTHLIIEREVHVCNNCGLLSENNDRMLAHVADEDSACFGMDVVAELMRDAYVCEYCSAYFKQKSDLSAHRNSGVHKDGHFWCHPCSKKFTDMKLYRHHLRNYQQLRTDFSHRRLEICLYYMCDNEKCTEAYINWNSLYTHKRRTHDAAEKQEPKLKDNEWICQFCQKVCRSKMSLSVHVARSHNNNNVACSLCKASYKDEEALKKHHAYWHERIECPMCLKVVKNRRNYDTHIKVVHSNKKRYSCSECQKGFYHKSEMEAHQRLHSQSFKCEQCNFTTRNKKSLSVHVLGQHYKRFAFKCKFCDKRFGRRQGLSNHTLHVHGSKFTCRDFFEGGCGKAFASMARLNVHVRKVHYGTQFLADDPTKLDEKEQAEEEAEEEAEEEAEEEEEPEASDGPSTSKKRLIRISANTEIEFISNAADADADDDNESLTDSEIFEEFKEVKAAAKQPPKKKPKPMTTRA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496807;
90% Identity: iTF_00511464; iTF_00500489; iTF_00552491; iTF_00499058; iTF_00535508;
80% Identity: -